蛋白

缺氧诱导因子1A, 1-85aa, 人类, 多聚组氨酸标签, 大肠杆菌

ATGP0730

50微克/10微克

720/240美元

缺氧诱导因子1A, 1-85aa, 人类, 多聚组氨酸标签, 大肠杆菌

蛋白

720/240美元

Hypoxia-inducible factor-1 (HIF-1), identified as one of the transcription factors, has been found to play an essential role in oxygen homeostasis. HIF-1 is a heterodimer composed of HIF-1 beta subunit and one of three subunits (Hif-1 alpha, Hif-2 alpha or Hif-3 alpha). The activation of Hif-1 alpha is closely associated with a variety of tumors and oncogenic pathways. Hif-1 alpha consists of DNA binding domain(DBD domain), dimerization domain and C-terminal regulatory domains, including two transactivation domains(TAD), an oxygen-dependent degradation(ODD) domain, and inhibitory domains. Recombinant human Hif-1 alpha (1-85) protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

人类

缺氧诱导因子甲, BHLHE78, MOP1, PASD8, 缺氧诱导因子甲

> 80 % by SDS - PAGE

Liquid. In 20mM Tris buffer(pH 8.0) containing 20% glycerol, 1mM DTT, 0.2M NaCl, 1mM EDTA.

50微克/10微克

0.25毫克/毫升(由布拉德福德Bradford检测确定)

可以储存在+4C短期(1-2周)。 为长期储存, 分成小份儿保存在-20C或-70C。 避免反复冻融

Okuyama H., et al. (2006) J Biol Chem. 281(22):15554-63.

NP_001521