蛋白

CD55, 35-353aa, 人类, 多聚组氨酸标签, 杆状病毒

ATGP3730

250微克/50微克

960/240美元

CD55, 35-353aa, 人类, 多聚组氨酸标签, 杆状病毒

蛋白

960/240美元

CD55, also known as complement decay-accelerating factor isoform 1, is a membrane protein that attaches to cell membrane via a glycophosphatidylinositol (GPI) anchor. It contains four complement control protein repeats (CCPs) with a single N-linked glycan positioned between CCPs 1 and 2. It regulates the complement system on the cell surface. It is used as a receptor by some coxsackieviruses and other enteroviruses. It is broadly distributed among hematopoietic and non-hematopoietic cells. It is a determinant for the Cromer blood group system. It plays a role promotion of tumorigenesis, decrease of complement mediated tumor cell lysis, autocrine loops for cell rescue and evasion of apoptosis, neoangiogenesis, invasiveness, cell motility. Recombinant human CD55, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

人类

Complement decay-accelerating factor isoform 1, CD55, CHAPLE, CR, CROM, DAF, TC

> 95% by SDS - PAGE

Liquid. In Phosphate Buffered Saline (pH 7.4) containing 10% glycerol.

250微克/50微克

0.5mg/ml (determined by BCA assay)

可以储存在+4C短期(1-2周)。 为长期储存, 分成小份儿保存在-20C或-70C。 避免反复冻融

Ozen A., et al. (2017) N Engl J Med. 377:52-61.; Brodbeck WG., et al. (2000) Immunology. 101:104-111.

NP_000565

< 1.0 EU per 1ug of protein (determined by LAL method)