蛋白

CD44, 21-220aa, Human, hIgG-His-tag, Baculovirus

ATGP3785

50微克/10微克

960/240美元

CD44, 21-220aa, Human, hIgG-His-tag, Baculovirus

蛋白

960/240美元

CD44, also known as CD44 antigen isoform 1, is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. The most extensively characterized ligand for CD44 is hyaluronan, a component of the extracellular matrix. It is expressed on the majority of immune cells. The binding of CD44 to hyaluronan is induced on T lymphocytes after activation by antigen and on monocytes after stimulation by inflammatory agents. It improves the prognostic efficacy of tumor differentiation. It might be determinant of differentiation characteristics, imparting properties of increased self-renewal, migration, and invasion. Also it involved in lymphocyte activation, recirculation and homing, and hematopoiesis. Recombinant human CD44, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

人类

CD44 antigen isoform 1, CD44, CDW44, CSPG8, ECMR-III, HCELL, HUTCH-I, IN, LHR, MC56, MDU2, MDU3, MIC4, Pgp1

> 95% by SDS - PAGE

Liquid. In Phosphate Buffered Saline (pH 7.4) containing 10% glycerol.

50微克/10微克

0.25mg/ml (determined by Absorbance at 280nm)

可以储存在+4C短期(1-2周)。 为长期储存, 分成小份儿保存在-20C或-70C。 避免反复冻融

Jackson DG., et al. (1992) Biol Chem. 267:4732-4739. Morine Y., et al. (2017) Anticancer Res. 37:5701-5705.

NP_000601

< 1.0 EU per 1ug of protein (determined by LAL method)