抗体

E2F转录因子1(E2F转录因子1)抗体

abx011766

100微升

单克隆

小鼠

未共轭

免疫印迹, 酶联免疫吸附测定, 免疫组化, 流式细胞仪

E2F转录因子1(E2F转录因子1)

E2F转录因子1(E2F转录因子1)抗体

E2F1

E2F转录因子1

一抗

小鼠

单克隆

未共轭

IgG1

100微升

The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein and another 2 members, E2F2 and E2F3, have an additional cyclin binding domain. This protein binds preferentially to retinoblastoma protein pRB in a cell-cycle dependent manner. It can mediate both cell proliferation and p53-dependent/independent apoptosis. [provided by RefSeq].

Q01094

E2F1_HUMAN

hsa:1869

9606.ENSP00000345571

Purified from ascites by Protein G chromatography.

PBS, 含0.05% 叠氮化钠

1毫克/毫升

酶联免疫吸附测定, 免疫印迹, 免疫组化, FCM

分成小份儿保存在-20°C。 避免反复冻融

液体

12352203

Shipped within 5-10 working days.

No