产品简要
公司名称 :
Abbexa
产品类型 :
抗体
产品名称 :
Receptor Tyrosine-Protein Kinase ErbB-2 (ERBB2) Antibody
目录 :
abx012006
规格 :
100微升
价格 :
420.5美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
反应物种 :
人类
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化
更多信息或购买 :
产品信息
目录代码 :
abx012006
靶标 :
v-erb-b2成红细胞白血病病毒致瘤基因2
产品名称 :
Receptor Tyrosine-Protein Kinase ErbB-2 (ERBB2) Antibody
简称 :
v-erb-b2成红细胞白血病病毒致瘤基因2
产品类型 :
一抗
宿主物种 :
小鼠
克隆性 :
单克隆
共轭 :
未共轭
抗体亚型 :
IgG1, IgG2b
规格1 :
100微升
价格1(美元) :
420.5美元
产品描述 :
This gene encodes a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases. This protein has no ligand binding domain of its own and therefore cannot bind growth factors. However, it does bind tightly to other ligand-bound EGF receptor family members to form a heterodimer, stabilizing ligand binding and enhancing kinase-mediated activation of downstream signalling pathways, such as those involving mitogen-activated protein kinase and phosphatidylinositol-3 kinase. Allelic variations at amino acid positions 654 and 655 of isoform a (positions 624 and 625 of isoform b) have been reported, with the most common allele, Ile654/Ile655, shown here. Amplification and/or overexpression of this gene has been reported in numerous cancers, including breast and ovarian tumors. Alternative splicing results in several additional transcript variants, some encoding different isoforms and others that have not been fully characterized.
UniProt Primary AC :
P04626
UniProt数据库进入名 :
ERBB2_HUMAN
基因符号 :
v-erb-b2成红细胞白血病病毒致瘤基因2
OMIM :
137800
HGNC :
3430
KEGG :
hsa:2064
Ensembl :
ENSG00000141736
String :
9606.ENSP00000269571
交叉活性 :
人类
免疫原 :
纯化重组片段对应于人v-erb-b2成红细胞白血病病毒致瘤基因2(aa750-987)在大肠杆菌中表达
纯化 :
Unpurified ascites.
缓冲液 :
腹水含0.03% 叠氮化钠
检测过的应用 :
酶联免疫吸附测定, 免疫印迹, 免疫组化
储存 :
分成小份儿保存在-20°C。 避免反复冻融
形式 :
液体
UNSPSC编码 :
12352203
分子量 :
180 kDa
Availability :
Shipped within 5-10 working days.
提示 :
This product is for research use only.
干冰 :
No
更多信息或购买 :
公司信息
Abbexa
Abbexa LTD, Cambridge, UK
Abbexa LLC, Houston, USA
info@abbexa.com
https://www.abbexa.com
44 (0)1223 75595
1 832 327 7413
公司总部: 英国
Abbexa is a biotechnology company based in Cambridge, UK, specializing in high quality, reliable research reagents for scientific research. We work in partnership with academic institutions, hospitals and laboratories across the world to bring an integrated source of antibodies, proteins, ELISA kits and other biological reagents. We are dedicated to providing excellent customer service, quality and affordable products to enable scientists to do better science. For more information, please visit http://www.abbexa.com/.