产品简要
公司名称 :
Abbexa
产品类型 :
抗体
产品名称 :
Mothers Against Decapentaplegic Homolog 2 (SMAD2) Antibody
目录 :
abx015993
规格 :
100微升
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
反应物种 :
人类, 小鼠, 大鼠,
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学, 流式细胞仪
更多信息或购买 :
产品信息
目录代码 :
abx015993
靶标 :
Mothers Against Decapentaplegic Homolog 2 (SMAD2)
产品名称 :
Mothers Against Decapentaplegic Homolog 2 (SMAD2) Antibody
简称 :
SMAD家族成员2
Long Name :
Mothers Against Decapentaplegic Homolog 2
类别 :
一抗
宿主 :
小鼠
克隆性 :
单克隆
共轭 :
未共轭
抗体亚型 :
IgG1
规格1 :
100微升
产品描述 :
The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C.elegans gene Sma.SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways.This protein mediates the signal of the transforming growth factor (TGF)-beta, and thus regulates multiple cellular processes, such as cell proliferation, apoptosis, and differentiation.This protein is recruited to the TGF-beta receptors through its interaction with the SMAD anchor for receptor activation (SARA) protein.In response to TGF-beta signal, this protein is phosphorylated by the TGF-beta receptors.The phosphorylation induces the dissociation of this protein with SARA and the association with the family member SMAD4.The association with SMAD4 is important for the translocation of this protein into the nucleus, where it binds to target promoters and forms a transcription repressor complex with other cofactors.This protein can also be phosphorylated by activin type 1 receptor kinase, and mediates the signal from the activin.Alternatively spliced transcript variants encoding the same protein have been observed.
纯化 :
Unpurified ascites.
缓冲液 :
腹水含0.03% 叠氮化钠
检测过的应用 :
酶联免疫吸附测定, 免疫印迹, 免疫组化, IF/免疫细胞化学, FCM
储存 :
分成小份儿保存在-20°C。 避免反复冻融
形式 :
液体
UNSPSC编码 :
12352203
Availability :
Shipped within 5-10 working days.
DryIce :
No
更多信息或购买 :
公司信息
Abbexa
Abbexa LTD, Cambridge, UK
Abbexa LLC, Houston, USA
info@abbexa.com
https://www.abbexa.com
44 (0)1223 75595
1 832 327 7413
公司总部: 英国
Abbexa is a biotechnology company based in Cambridge, UK, specializing in high quality, reliable research reagents for scientific research. We work in partnership with academic institutions, hospitals and laboratories across the world to bring an integrated source of antibodies, proteins, ELISA kits and other biological reagents. We are dedicated to providing excellent customer service, quality and affordable products to enable scientists to do better science. For more information, please visit http://www.abbexa.com/.