抗体

Neuroendocrine Secretory Protein 55 (GNAS) Antibody

abx025004

100微升

单克隆

小鼠

未共轭

人类, 小鼠

免疫印迹, 酶联免疫吸附测定

Neuroendocrine Secretory Protein 55 (GNAS)

Neuroendocrine Secretory Protein 55 (GNAS) Antibody

GNAS

Neuroendocrine Secretory Protein 55

一抗

小鼠

单克隆

未共轭

IgM

100微升

Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The Gs protein is involved in hormonal regulation of adenylate cyclase: it activates the cyclase in response to beta-adrenergic stimuli. Alternative splicing of downstream exons of the GNAS gene is observed, which results in different forms of the stimulatory G protein alpha subunit, a key element of the classical signal transduction pathway linking receptor-ligand interactions with the activation of adenylyl cyclase and a variety of cellular reponses. Multiple transcript variants have been found for this gene, but the full-length nature and/or biological validity of some variants have not been determined. Mutations in this gene result in pseudohypoparathyroidism type 1a, pseudohypoparathyroidism type 1b, Albright hereditary osteodystrophy, pseudopseudohypoparathyroidism, McCune-Albright syndrome, progressive osseus heteroplasia, polyostotic fibrous dysplasia of bone, and some pituitary tumors. This antibody is supplied as crude ascites.

Q5FWY2

Unpurified crude ascites.

腹水含0.09% 叠氮化钠

酶联免疫吸附测定, 免疫印迹

分成小份儿保存在-20°C。 避免反复冻融

液体

12352203

Shipped within 5-10 working days.

No