抗体

Signal Transducer and Activator of Transcription 3 Phospho-Ser727 (STAT3 pS727) Antibody

abx031919

80微升

多克隆

domestic rabbit

未共轭

人类, 小鼠

免疫印迹, 酶联免疫吸附测定, 免疫细胞化学

Signal Transducer and Activator of Transcription 3 Phospho-Ser727 (STAT3 pS727)

Signal Transducer and Activator of Transcription 3 Phospho-Ser727 (STAT3 pS727) Antibody

STAT3 pS727

Signal Transducer and Activator of Transcription 3 Phospho-Ser727

一抗

兔

多克隆

Ser727

未共轭

IgG

80微升

400微升

STAT3 is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated through phosphorylation in response to various cytokines and growth factors including IFNs, EGF, IL5, IL6, HGF, LIF and BMP2. It mediates the expression of a variety of genes in response to cell stimuli, and thus plays a key role in many cellular processes such as cell growth and apoptosis. The small GTPase Rac1 has been shown to bind and regulate the activity of this protein. PIAS3 protein is a specific inhibitor of this protein.

P40763

STAT3_HUMAN

hsa:6774

9606.ENSP00000264657

Purified by protein G affinity chromatography. Then, the antibody fraction was peptide affinity purified in a 2-step procedure with control and phosphorylated peptides. The phospho-specific antibody was eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

PBS含0.09% 叠氮化钠

酶联免疫吸附测定, 免疫印迹, IF/免疫细胞化学

分成小份儿保存在-20°C。 避免反复冻融

液体

12352203

Shipped within 5-10 working days.

No