抗体

鼠双微基因2 p53结合蛋白同系物磷酸化Ser395(鼠双微基因2 pS395)抗体

abx032037

80微升

多克隆

domestic rabbit

未共轭

鼠双微基因2 p53结合蛋白同系物磷酸化Ser395(鼠双微基因2 pS395)

鼠双微基因2 p53结合蛋白同系物磷酸化Ser395(鼠双微基因2 pS395)抗体

鼠双微基因2 pS395

鼠双微基因2 p53结合蛋白同系物磷酸化Ser395

一抗

兔

多克隆

Ser395

未共轭

IgG

80微升

400微升

MDM2 is a target of the transcription factor tumor protein p53. This protein is a nuclear phosphoprotein that binds and inhibits transactivation by tumor protein p53, as part of an autoregulatory negative feedback loop. Overexpression of MDM2 can result in excessive inactivation of tumor protein p53, diminishing its tumor suppressor function. This protein has E3 ubiquitin ligase activity, which targets tumor protein p53 for proteasomal degradation. MDM2 also affects the cell cycle, apoptosis, and tumorigenesis through interactions with other proteins, including retinoblastoma 1 and ribosomal protein L5.

Q00987

Purified through a protein A column, followed by two-step phosphospecific peptide affinity purification.

PBS含0.09% 叠氮化钠

酶联免疫吸附测定, DB

分成小份儿保存在-20°C。 避免反复冻融

液体

12352203

Shipped within 5-10 working days.

No