产品简要
公司名称 :
Abbexa
产品类型 :
抗体
产品名称 :
纤维母细胞生长因子受体2抗体
目录 :
abx033560
规格 :
5微升
价格 :
29美元
克隆性 :
多克隆
宿主 :
共轭标签 :
未共轭
反应物种 :
人类
应用 :
免疫印迹, 免疫细胞化学, 流式细胞仪
更多信息或购买 :
产品信息
Model :
abx033560
类别 :
一抗
靶标 :
纤维母细胞生长因子受体2
名称 :
纤维母细胞生长因子受体2抗体
简称 :
纤维母细胞生长因子受体2
Long Name :
成纤维细胞生长因子受体2
描述 :
FGFR2 is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member is a high-affinity receptor for acidic, basic and/or keratinocyte growth factor, depending on the isoform. Mutations in the gene for FGFR2 are associated with many craniosynostotic syndromes and bone malformations. The genomic organization of the gene encompasses 20 exons. Alternative splicing in multiple exons, including those encoding the Ig-like domains, the transmembrane region and the carboxyl terminus, results in varied isoforms which differ in structure and specificity. Isoform 1 has equal affinity for aFGF and bFGF but does not bind KGF.
同义词 :
bacteria-expressed kinase; BEK; BEK fibroblast growth factor receptor; BFR-1; CD332; CEK3; CFD1; ECT1; FGF receptor; FGFR-2; FGFR2; Fibroblast growth factor receptor 2; FLJ98662; hydroxyaryl-protein kinase; JWS; K-sam; Keratinocyte growth factor receptor; KGFR; KSAM; protein tyrosine kinase; receptor like 14; soluble FGFR4 variant 4; TK14; TK25; keratinocyte grow; Keratinocyte growth factor receptor 2
规格1 :
5微升
规格2 :
80微升
规格3 :
400微升
价格1(美元) :
29美元
价格2(美元) :
326.25
价格3(美元) :
551
克隆性 :
多克隆
反应物种 :
人类
检测过的应用 :
免疫印迹, IF/免疫细胞化学, FCM
宿主 :
共轭 :
未共轭
抗体亚型 :
IgG
纯化 :
纯化兔多克隆抗体
储存 :
分成小份儿保存在-20°C。 避免反复冻融
UNSPSC编码 :
12352203
Swiss Prot数据库 :
P21802
基因符号 :
纤维母细胞生长因子受体2
OMIM :
101200
NCBI登录号 :
NP_000132.3, NP_001138385.1, NP_001138386.1, NP_001138387.1, NP_001138388.1, NP_001138389.1, NP_001138390.1, NP_001138391.1, NP_075259.4, NP_075418.1
HGNC :
3689
Ensembl :
ENSG00000066468
Availability :
Shipped within 5-10 working days.
提示 :
This product is for research use only.
更多信息或购买 :
公司信息
Abbexa
181 Cambridge Science Park
Cambridge, CB4 0GJ
info@abbexa.com
https://www.abbexa.com
1 832 327 7413
44 (0)1223 75595
公司总部: 英国
Abbexa is a biotechnology company based in Cambridge, UK, specializing in high quality, reliable research reagents for scientific research. We work in partnership with academic institutions, hospitals and laboratories across the world to bring an integrated source of antibodies, proteins, ELISA kits and other biological reagents. We are dedicated to providing excellent customer service, quality and affordable products to enable scientists to do better science. For more information, please visit http://www.abbexa.com/.