产品简要
公司名称 :
Abbexa
产品类型 :
抗体
产品名称 :
成纤维细胞生长因子受体2(纤维母细胞生长因子受体2)抗体
目录 :
abx033560
规格 :
80微升
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
反应物种 :
人类
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫细胞化学, 流式细胞仪
更多信息或购买 :
产品信息
目录代码 :
abx033560
靶标 :
成纤维细胞生长因子受体2(纤维母细胞生长因子受体2)
产品名称 :
成纤维细胞生长因子受体2(纤维母细胞生长因子受体2)抗体
简称 :
纤维母细胞生长因子受体2
Long Name :
成纤维细胞生长因子受体2
类别 :
一抗
宿主 :
克隆性 :
多克隆
共轭 :
未共轭
抗体亚型 :
IgG
规格1 :
80微升
规格2 :
400微升
产品描述 :
FGFR2 is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member is a high-affinity receptor for acidic, basic and/or keratinocyte growth factor, depending on the isoform. Mutations in the gene for FGFR2 are associated with many craniosynostotic syndromes and bone malformations. The genomic organization of the gene encompasses 20 exons. Alternative splicing in multiple exons, including those encoding the Ig-like domains, the transmembrane region and the carboxyl terminus, results in varied isoforms which differ in structure and specificity. Isoform 1 has equal affinity for aFGF and bFGF but does not bind KGF.
UniProt Primary AC :
P21802
UniProt数据库进入名 :
FGFR2_HUMAN
NCBI登录号 :
NP_000132.3, NP_001138385.1, NP_001138386.1, NP_001138387.1, NP_001138388.1, NP_001138389.1, NP_001138390.1, NP_001138391.1, NP_075259.4, NP_075418.1
KEGG :
hsa:2263
String :
9606.ENSP00000410294
纯化 :
纯化兔多克隆抗体
缓冲液 :
PBS含0.09% 叠氮化钠
检测过的应用 :
酶联免疫吸附测定, 免疫印迹, IF/免疫细胞化学, FCM
储存 :
分成小份儿保存在-20°C。 避免反复冻融
形式 :
液体
UNSPSC编码 :
12352203
Availability :
Shipped within 5-10 working days.
DryIce :
No
更多信息或购买 :
公司信息
Abbexa
Abbexa LTD, Cambridge, UK
Abbexa LLC, Houston, USA
info@abbexa.com
https://www.abbexa.com
44 (0)1223 75595
1 832 327 7413
公司总部: 英国
Abbexa is a biotechnology company based in Cambridge, UK, specializing in high quality, reliable research reagents for scientific research. We work in partnership with academic institutions, hospitals and laboratories across the world to bring an integrated source of antibodies, proteins, ELISA kits and other biological reagents. We are dedicated to providing excellent customer service, quality and affordable products to enable scientists to do better science. For more information, please visit http://www.abbexa.com/.