This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
产品简要
公司名称 :
Abbiotec
产品类型 :
抗体
产品名称 :
胱氨酸-天冬氨酸蛋白酶3抗体
目录 :
250573
规格 :
0.1毫克
价格 :
251美元
克隆性 :
多克隆
宿主 :
兔
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫沉淀, immunohistochemistry - free floating section
文章摘录数: 3
已发表的文献中的应用方法／种属／稀释度参考文献
  • immunohistochemistry - free floating section; 大鼠; 1:200; 图 6
Szczepanski S, Hussain M, Sur I, Altmuller J, Thiele H, Abdullah U, et al. A novel homozygous splicing mutation of CASC5 causes primary microcephaly in a large Pakistani family. Hum Genet. 2016;135:157-70 pubmed 出版商
  • immunohistochemistry - free floating section; 大鼠; 1:200; 图 6
AbdEl-Moniem M, Mustafa H, Megahed H, Agaibyi M, Hegazy G, El-Dabaa M. The ameliorative potential of Hyphaene thebaica on streptozotocin-induced diabetic nephropathy. Folia Morphol (Warsz). 2015;74:447-57 pubmed 出版商
Çiftçi Z, Kirzioglu Z, Naziroglu M, Ozmen O. Effects of prenatal and postnatal exposure of Wi-Fi on development of teeth and changes in teeth element concentration in rats. [corrected]. Biol Trace Elem Res. 2015;163:193-201 pubmed 出版商
产品信息
产品名称 :
胱氨酸-天冬氨酸蛋白酶3抗体
产品子类型 :
兔多克隆抗体
目录号 :
250573
单位 :
0.1毫克
价格 :
251美元
产品种类 :
抗体
蛋白家族 :
Peptidases, Enzymes
通路和疾病 :
Signal Transduction, Cell Growth and Death, Immune System, Cancers, Neurodegenerative Disorders, Infectious Diseases
描述 :
Caspase-3 is involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis, Caspase-3 proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a 216-Asp- -Gly-217 bond as well as cleaving and activating the sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. In addition Caspase-3 cleaves and activates caspase-6, -7, -9.
格式 :
Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
应用 :
E, 免疫印迹, 免疫组化, 免疫沉淀
产品传票 :
Haligur M et al. 2012. Expriemental Diabetes Research. 2012:120645. PMID# 22844268.
又名 :
Caspase-3; CASP-3; Apopain; Cysteine protease CPP32; CPP-32; Yana protein; SREBP cleavage activity 1; SCA-1; CASP3; CPP32
登录号 :
P42574
抗体亚型 :
兔IgE
抗原 :
KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human Caspase-3.
物种活性 :
H, M, R
应用注释 :
E: 1:500-1:1, 000;WB: 1:100-1:500;IHC: 1:200-1:500
储存 :
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
公司信息
Abbiotec
7985 Dunbrook Road, Suite A
San Diego, CA 92126
info@abbiotec.com
www.abbiotec.com
858-586-0500 800-854-7453
公司总部: 美国
Abbiotec致力于开发细胞生物学研究用产品，帮助研究人员探索人类蛋白组中功能、作用及调控机制。