产品简要
公司名称 :
艾博抗(上海)贸易有限公司
其他品牌 :
Epitomics, Ascent Scientific, MitoSciences
产品类型 :
抗体
产品名称 :
Anti-NeuN antibody [1B7] - Neuronal Marker
目录 :
ab104224
规格 :
50微升
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
1B7
反应物种 :
人类, 小鼠, 大鼠, , , 猕猴
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫组化-石蜡切片, 免疫组化-冰冻切片, 免疫组化-自由浮动切片
文章摘录数: 68
出版应用/物种/样本/稀释参考文献
  • 免疫组化; 小鼠; 1:500
Zhang X, Liu Y, Hong X, Li X, Meshul C, Moore C, et al. NG2 glia-derived GABA release tunes inhibitory synapses and contributes to stress-induced anxiety. Nat Commun. 2021;12:5740 pubmed 出版商
  • 免疫组化; 小鼠; 1:100; 图 2d
He W, Lu Q, Sherchan P, Huang L, Hu X, Zhang J, et al. Activation of Frizzled-7 attenuates blood-brain barrier disruption through Dvl/β-catenin/WISP1 signaling pathway after intracerebral hemorrhage in mice. Fluids Barriers CNS. 2021;18:44 pubmed 出版商
  • 免疫组化; 小鼠; 1:500; 图 1c
Zeng H, Chen H, Li M, Zhuang J, Peng Y, Zhou H, et al. Autophagy protein NRBF2 attenuates endoplasmic reticulum stress-associated neuroinflammation and oxidative stress via promoting autophagosome maturation by interacting with Rab7 after SAH. J Neuroinflammation. 2021;18:210 pubmed 出版商
  • 免疫组化; 小鼠; 1:500; 图 s7a
Zhang D, Yamaguchi S, Zhang X, Yang B, Kurooka N, Sugawara R, et al. Upregulation of Mir342 in Diet-Induced Obesity Mouse and the Hypothalamic Appetite Control. Front Endocrinol (Lausanne). 2021;12:727915 pubmed 出版商
  • 免疫组化-自由浮动切片; 小鼠; 图 s2a
  • 免疫细胞化学; 小鼠; 1:200; 图 2c
Chen H, Teng Y, Chen X, Liu Z, Geng F, Liu Y, et al. Platelet-derived growth factor (PDGF)-BB protects dopaminergic neurons via activation of Akt/ERK/CREB pathways to upregulate tyrosine hydroxylase. CNS Neurosci Ther. 2021;27:1300-1312 pubmed 出版商
  • 免疫组化; 小鼠; 图 2d
Teng Y, Liu Z, Chen X, Liu Y, Geng F, Le W, et al. Conditional deficiency of m6A methyltransferase Mettl14 in substantia nigra alters dopaminergic neuron function. J Cell Mol Med. 2021;25:8567-8572 pubmed 出版商
  • 免疫细胞化学; 小鼠; 1:1000; 图 s4-1a
O Neil S, Racz B, Brown W, Gao Y, Soderblom E, Yasuda R, et al. Action potential-coupled Rho GTPase signaling drives presynaptic plasticity. elife. 2021;10: pubmed 出版商
  • 免疫组化; 大鼠; 1:1000; 图 4a, 5a
Liu L, Xu X, Qu Z, Zhao L, Zhang C, Li Z, et al. Determining 5HT7R's Involvement in Modifying the Antihyperalgesic Effects of Electroacupuncture on Rats With Recurrent Migraine. Front Neurosci. 2021;15:668616 pubmed 出版商
  • 免疫组化; 小鼠; 1:1000; 图 1g
Mu W, Li S, Xu J, Guo X, Wu H, Chen Z, et al. Hypothalamic Rax+ tanycytes contribute to tissue repair and tumorigenesis upon oncogene activation in mice. Nat Commun. 2021;12:2288 pubmed 出版商
  • 免疫组化; 小鼠; 1:1000; 图 6??s2b
Courtland J, Bradshaw T, Waitt G, Soderblom E, Ho T, Rajab A, et al. Genetic disruption of WASHC4 drives endo-lysosomal dysfunction and cognitive-movement impairments in mice and humans. elife. 2021;10: pubmed 出版商
  • 免疫组化; 小鼠; 图 s4
Zhang X, Gou Y, Zhang Y, Li J, Han K, Xu Y, et al. Hepcidin overexpression in astrocytes alters brain iron metabolism and protects against amyloid-β induced brain damage in mice. Cell Death Discov. 2020;6:113 pubmed 出版商
  • 免疫组化; 小鼠; 1:100; 图 2b
Liu D, Bai X, Ma W, Xin D, Chu X, Yuan H, et al. Purmorphamine Attenuates Neuro-Inflammation and Synaptic Impairments After Hypoxic-Ischemic Injury in Neonatal Mice via Shh Signaling. Front Pharmacol. 2020;11:204 pubmed 出版商
  • 免疫印迹; 大鼠; 1:200; 图 2, 3, 4
Ma X, Agas A, Siddiqui Z, Kim K, Iglesias Montoro P, Kalluru J, et al. Angiogenic peptide hydrogels for treatment of traumatic brain injury. Bioact Mater. 2020;5:124-132 pubmed 出版商
  • 免疫组化; 大鼠; 图 1a
Liu R, Ma J, Wang B, Tian T, Guo N, Liu S. No DCX-positive neurogenesis in the cerebral cortex of the adult primate. Neural Regen Res. 2020;15:1290-1299 pubmed 出版商
  • 免疫组化-石蜡切片; 大鼠; 1:300; 图 5a
Han C, Liu Y, Sui Y, Chen N, Du T, Jiang Y, et al. Integrated transcriptome expression profiling reveals a novel lncRNA associated with L-DOPA-induced dyskinesia in a rat model of Parkinson's disease. Aging (Albany NY). 2020;12:718-739 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 图 s4b
Smith H, Freeman O, Butcher A, Holmqvist S, Humoud I, Schätzl T, et al. Astrocyte Unfolded Protein Response Induces a Specific Reactivity State that Causes Non-Cell-Autonomous Neuronal Degeneration. Neuron. 2020;: pubmed 出版商
  • 免疫组化; 小鼠; 1:500; 图 10a
Anstötz M, Maccaferri G. A Toolbox of Criteria for Distinguishing Cajal-Retzius Cells from Other Neuronal Types in the Postnatal Mouse Hippocampus. Eneuro. 2020;7: pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:300; 图 2a
Schoof M, Launspach M, Holdhof D, Nguyen L, Engel V, Filser S, et al. The transcriptional coactivator and histone acetyltransferase CBP regulates neural precursor cell development and migration. Acta Neuropathol Commun. 2019;7:199 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 图 8a
Zhou C, Sun X, Hu Y, Song J, Dong S, Kong D, et al. Genomic deletion of TLR2 induces aggravated white matter damage and deteriorated neurobehavioral functions in mouse models of Alzheimer's disease. Aging (Albany NY). 2019;11:7257-7273 pubmed 出版商
  • 免疫细胞化学; 大鼠; 1:1000; 图 6g
Chao H, Lin C, Zuo Q, Liu Y, Xiao M, Xu X, et al. Cardiolipin-Dependent Mitophagy Guides Outcome after Traumatic Brain Injury. J Neurosci. 2019;39:1930-1943 pubmed 出版商
  • 免疫组化; 大鼠; 1:100; 图 6
Wang Y, Lin Y, Wu Y, Yao Z, Tang J, Shen L, et al. Expression and Cellular Localization of IFITM1 in Normal and Injured Rat Spinal Cords. J Histochem Cytochem. 2018;66:175-187 pubmed 出版商
  • 免疫组化-冰冻切片; 大鼠; 1:500; 图 7a
Rong H, Zhao Z, Feng J, Lei Y, Wu H, Sun R, et al. The effects of dexmedetomidine pretreatment on the pro- and anti-inflammation systems after spinal cord injury in rats. Brain Behav Immun. 2017;64:195-207 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:100; 图 4a
  • 免疫组化-石蜡切片; 小鼠; 1:100; 图 2b
Yamanishi E, Hasegawa K, Fujita K, Ichinose S, Yagishita S, Murata M, et al. A novel form of necrosis, TRIAD, occurs in human Huntington's disease. Acta Neuropathol Commun. 2017;5:19 pubmed 出版商
  • 免疫组化-石蜡切片; 猕猴; 1:200; 图 4
Schmidt A, Kannan P, Chougnet C, Danzer S, Miller L, Jobe A, et al. Intra-amniotic LPS causes acute neuroinflammation in preterm rhesus macaques. J Neuroinflammation. 2016;13:238 pubmed 出版商
  • 免疫组化-石蜡切片; 大鼠; 图 1
  • 免疫细胞化学; 大鼠; 图 1
Zhai W, Chen D, Shen H, Chen Z, Li H, Yu Z, et al. A1 adenosine receptor attenuates intracerebral hemorrhage-induced secondary brain injury in rats by activating the P38-MAPKAP2-Hsp27 pathway. Mol Brain. 2016;9:66 pubmed 出版商
  • 免疫组化-冰冻切片; 大鼠; 1:400; 图 2
Xu Y, Liu J, He M, Liu R, Belegu V, Dai P, et al. Mechanisms of PDGF siRNA-mediated inhibition of bone cancer pain in the spinal cord. Sci Rep. 2016;6:27512 pubmed 出版商
  • 免疫细胞化学; 大鼠; 1:500; 图 2
Gebremedhin D, Zhang D, Carver K, Rau N, Rarick K, Roman R, et al. Expression of CYP 4A ?-hydroxylase and formation of 20-hydroxyeicosatetreanoic acid (20-HETE) in cultured rat brain astrocytes. Prostaglandins Other Lipid Mediat. 2016;124:16-26 pubmed 出版商
  • 免疫组化; 大鼠; 1:500; 表 2
Vasilev D, Dubrovskaya N, Tumanova N, Zhuravin I. Prenatal Hypoxia in Different Periods of Embryogenesis Differentially Affects Cell Migration, Neuronal Plasticity, and Rat Behavior in Postnatal Ontogenesis. Front Neurosci. 2016;10:126 pubmed 出版商
  • 免疫印迹; 小鼠; 1:800
Jiang T, Zhang Y, Chen Q, Gao Q, Zhu X, Zhou J, et al. TREM2 modifies microglial phenotype and provides neuroprotection in P301S tau transgenic mice. Neuropharmacology. 2016;105:196-206 pubmed 出版商
  • 免疫细胞化学; 人类; 1:100; 图 6
García Castro I, Garcia Lopez G, Avila González D, Flores Herrera H, Molina Hernández A, Portillo W, et al. Markers of Pluripotency in Human Amniotic Epithelial Cells and Their Differentiation to Progenitor of Cortical Neurons. PLoS ONE. 2015;10:e0146082 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:100; 图 7
Kang J, Shen W, Zhou C, Xu D, Macdonald R. The human epilepsy mutation GABRG2(Q390X) causes chronic subunit accumulation and neurodegeneration. Nat Neurosci. 2015;18:988-96 pubmed 出版商
  • 免疫细胞化学; 大鼠
Li B, Li H, Wang Z, Wang Y, Gao A, Cui Y, et al. Evidence for the role of phosphatidylcholine-specific phospholipase in experimental subarachnoid hemorrhage in rats. Exp Neurol. 2015;272:145-51 pubmed 出版商
  • 免疫组化; 小鼠; 1:250
Taylor J, Minter M, Newman A, Zhang M, Adlard P, Crack P. Type-1 interferon signaling mediates neuro-inflammatory events in models of Alzheimer's disease. Neurobiol Aging. 2014;35:1012-23 pubmed 出版商
  • 免疫组化; 大鼠; 1:200
Chio C, Chang C, Wang C, Cheong C, Chao C, Cheng B, et al. Etanercept attenuates traumatic brain injury in rats by reducing early microglial expression of tumor necrosis factor-?. BMC Neurosci. 2013;14:33 pubmed 出版商
Greer C, Wright J, Weiss J, Lazarenko R, Moran S, Zhu J, et al. Tet1 Isoforms Differentially Regulate Gene Expression, Synaptic Transmission, and Memory in the Mammalian Brain. J Neurosci. 2021;41:578-593 pubmed 出版商
Ramesh N, Daley E, Gleixner A, Mann J, Kour S, Mawrie D, et al. RNA dependent suppression of C9orf72 ALS/FTD associated neurodegeneration by Matrin-3. Acta Neuropathol Commun. 2020;8:177 pubmed 出版商
Fielder E, Tweedy C, Wilson C, Oakley F, LeBeau F, Passos J, et al. Anti-inflammatory treatment rescues memory deficits during aging in nfkb1-/- mice. Aging Cell. 2020;19:e13188 pubmed 出版商
Tan Z, Chen L, Ren Y, Jiang X, Gao W. Neuroprotective effects of FK866 against traumatic brain injury: Involvement of p38/ERK pathway. Ann Clin Transl Neurol. 2020;7:742-756 pubmed 出版商
Zhang M, Du W, Acklin S, Jin S, Xia F. SIRT2 protects peripheral neurons from cisplatin-induced injury by enhancing nucleotide excision repair. J Clin Invest. 2020;130:2953-2965 pubmed 出版商
Huang Y, Gu C, Wang Q, Xu L, Chen J, Zhou W, et al. The protective effort of GPCR kinase 2-interacting protein-1 in neurons via promoting Beclin1-Parkin induced mitophagy at the early stage of spinal cord ischemia-reperfusion injury. FASEB J. 2020;34:2055-2074 pubmed 出版商
Pesini A, Iglesias E, Bayona Bafaluy M, Garrido Pérez N, Meade P, Gaudó P, et al. Brain pyrimidine nucleotide synthesis and Alzheimer disease. Aging (Albany NY). 2019;11:8433-8462 pubmed 出版商
Woodward N, Haghani A, Johnson R, Hsu T, Saffari A, Sioutas C, et al. Prenatal and early life exposure to air pollution induced hippocampal vascular leakage and impaired neurogenesis in association with behavioral deficits. Transl Psychiatry. 2018;8:261 pubmed 出版商
Abdullah A, Zhang M, Frugier T, Bedoui S, Taylor J, Crack P. STING-mediated type-I interferons contribute to the neuroinflammatory process and detrimental effects following traumatic brain injury. J Neuroinflammation. 2018;15:323 pubmed 出版商
Xu W, Lu X, Zheng J, Li T, Gao L, Lenahan C, et al. Melatonin Protects Against Neuronal Apoptosis via Suppression of the ATF6/CHOP Pathway in a Rat Model of Intracerebral Hemorrhage. Front Neurosci. 2018;12:638 pubmed 出版商
Liang B, Zhang L, Barbera G, Fang W, Zhang J, Chen X, et al. Distinct and Dynamic ON and OFF Neural Ensembles in the Prefrontal Cortex Code Social Exploration. Neuron. 2018;100:700-714.e9 pubmed 出版商
Nguyen T, Su C, Singh M. Let-7i inhibition enhances progesterone-induced functional recovery in a mouse model of ischemia. Proc Natl Acad Sci U S A. 2018;115:E9668-E9677 pubmed 出版商
Zhang F, Wang Y, Wang T, Yao L, Lam S, Huang X, et al. cTAGE5/MEA6 plays a critical role in neuronal cellular components trafficking and brain development. Proc Natl Acad Sci U S A. 2018;115:E9449-E9458 pubmed 出版商
Li X, Yu Q, Chen F, Tan W, Zhang Z, Ma H. Inhibiting aberrant p53-PUMA feedback loop activation attenuates ischaemia reperfusion-induced neuroapoptosis and neuroinflammation in rats by downregulating caspase 3 and the NF-κB cytokine pathway. J Neuroinflammation. 2018;15:250 pubmed 出版商
Luo F, Zhang J, Burke K, Romito Digiacomo R, Miller R, Yang Y. Oligodendrocyte-specific loss of Cdk5 disrupts the architecture of nodes of Ranvier as well as learning and memory. Exp Neurol. 2018;306:92-104 pubmed 出版商
Sun L, Zhang K, Zhai W, Li H, Shen H, Yu Z, et al. TAR DNA Binding Protein-43 Loss of Function Induced by Phosphorylation at S409/410 Blocks Autophagic Flux and Participates in Secondary Brain Injury After Intracerebral Hemorrhage. Front Cell Neurosci. 2018;12:79 pubmed 出版商
Kemp K, Hares K, Redondo J, Cook A, Haynes H, Burton B, et al. Bone marrow transplantation stimulates neural repair in Friedreich's ataxia mice. Ann Neurol. 2018;83:779-793 pubmed 出版商
Xie C, Gu A, Cai J, Wu Y, Chen R. Curcumin protects neural cells against ischemic injury in N2a cells and mouse brain with ischemic stroke. Brain Behav. 2018;8:e00921 pubmed 出版商
Torres L, Robinson S, Kim D, Yan A, Cleland T, Bynoe M. Toxoplasma gondii alters NMDAR signaling and induces signs of Alzheimer's disease in wild-type, C57BL/6 mice. J Neuroinflammation. 2018;15:57 pubmed 出版商
Chang L, Lin H, Huang S, Chen I, Chu K, Chih C, et al. Blockade of soluble epoxide hydrolase attenuates post-ischemic neuronal hyperexcitation and confers resilience against stroke with TrkB activation. Sci Rep. 2018;8:118 pubmed 出版商
Ebbers L, Weber M, Nothwang H. Activity-dependent formation of a vesicular inhibitory amino acid transporter gradient in the superior olivary complex of NMRI mice. BMC Neurosci. 2017;18:75 pubmed 出版商
Li Y, Zhang Y, Wang L, Wang P, Xue Y, Li X, et al. Autophagy impairment mediated by S-nitrosation of ATG4B leads to neurotoxicity in response to hyperglycemia. Autophagy. 2017;13:1145-1160 pubmed 出版商
Sharma A, Ansari A, Kumari R, Pandey R, Rehman R, Mehani B, et al. Human brain harbors single nucleotide somatic variations in functionally relevant genes possibly mediated by oxidative stress. F1000Res. 2016;5:2520 pubmed 出版商
Kemp K, Cerminara N, Hares K, Redondo J, Cook A, Haynes H, et al. Cytokine therapy-mediated neuroprotection in a Friedreich's ataxia mouse model. Ann Neurol. 2017;81:212-226 pubmed 出版商
Tang W, Hsu Y, Wang C, Hu C, Chio C, Kuo J. Early electroacupuncture treatment ameliorates neuroinflammation in rats with traumatic brain injury. BMC Complement Altern Med. 2016;16:470 pubmed
Ishikawa M, Yoshitomi T, Zorumski C, Izumi Y. 24(S)-Hydroxycholesterol protects the ex vivo rat retina from injury by elevated hydrostatic pressure. Sci Rep. 2016;6:33886 pubmed 出版商
Wang Z, Wang Y, Tian X, Shen H, Dou Y, Li H, et al. Transient receptor potential channel 1/4 reduces subarachnoid hemorrhage-induced early brain injury in rats via calcineurin-mediated NMDAR and NFAT dephosphorylation. Sci Rep. 2016;6:33577 pubmed 出版商
Waung M, Akerman S, Wakefield M, Keywood C, Goadsby P. Metabotropic glutamate receptor 5: a target for migraine therapy. Ann Clin Transl Neurol. 2016;3:560-71 pubmed 出版商
Zhu J, Li Y, Wang Z, Jia W, Xu R. Toll-Like Receptor 4 Deficiency Impairs Motor Coordination. Front Neurosci. 2016;10:33 pubmed 出版商
Zhang W, Zhang L, Liang B, Schroeder D, Zhang Z, Cox G, et al. Hyperactive somatostatin interneurons contribute to excitotoxicity in neurodegenerative disorders. Nat Neurosci. 2016;19:557-559 pubmed 出版商
Gilkes J, Bloom M, Heldermon C. Mucopolysaccharidosis IIIB confers enhanced neonatal intracranial transduction by AAV8 but not by 5, 9 or rh10. Gene Ther. 2016;23:263-71 pubmed 出版商
Frankowski J, Demars K, Ahmad A, Hawkins K, Yang C, Leclerc J, et al. Detrimental role of the EP1 prostanoid receptor in blood-brain barrier damage following experimental ischemic stroke. Sci Rep. 2015;5:17956 pubmed 出版商
Masson G, Nair A, Dange R, Silva Soares P, Michelini L, Francis J. Toll-like receptor 4 promotes autonomic dysfunction, inflammation and microglia activation in the hypothalamic paraventricular nucleus: role of endoplasmic reticulum stress. PLoS ONE. 2015;10:e0122850 pubmed 出版商
Huang J, Shang L, Zhang M, Wang H, Chen D, Tong J, et al. Differential neuronal expression of receptor interacting protein 3 in rat retina: involvement in ischemic stress response. BMC Neurosci. 2013;14:16 pubmed 出版商
产品信息
目录号 :
ab104224
ItemName :
Anti-NeuN antibody [1B7] - Neuronal Marker
产品类型 :
一抗
宿主物种 :
小鼠
克隆性 :
单克隆
共轭标签 :
Not Conjugated
抗原修饰 :
No Modifications
克隆名称 :
1B7
规格 :
50微升
物种摘要 :
Cat, Chk, Cow, Dog, Goat, Hu, Mmst, Ms, Pig, Rat, S urc
用途 :
ICC/IF, IHC-FoFr, IHC-Fr, IHC-P, WB
规格说明 :
Other sizes available: 100 µg,100 µl
公司信息
艾博抗(上海)贸易有限公司
上海市浦东新区伽利略路338号5幢4层5401室
cn.technical@abcam.com
http://www.abcam.cn
400-628-6880 86-21-5110 5938
公司总部: 英国
Abcam是全球知名的生命科学研究领域产品提供商,产品涵盖一抗、二抗、蛋白、多肽及ELISA kit。