产品简要
公司名称 :
艾博抗(上海)贸易有限公司
其他品牌 :
Epitomics, Ascent Scientific, MitoSciences
产品类型 :
抗体
产品名称 :
Anti-Nucleophosmin antibody [FC82291]
目录 :
ab10530
规格 :
100微升
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
FC82291
反应物种 :
人类, 小鼠, 大鼠, ,
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫细胞化学, 免疫沉淀, 免疫组化-石蜡切片, 免疫组化-冰冻切片, 其他, 免疫印迹基因敲除验证
文章摘录数: 39
出版应用/物种/样本/稀释参考文献
  • 免疫细胞化学; 人类; 图 2d
Kanellis D, Espinoza J, Zisi A, Sakkas E, Bartkova J, Katsori A, et al. The exon-junction complex helicase eIF4A3 controls cell fate via coordinated regulation of ribosome biogenesis and translational output. Sci Adv. 2021;7: pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 2d
Höllmüller E, Geigges S, Niedermeier M, Kammer K, Kienle S, Rösner D, et al. Site-specific ubiquitylation acts as a regulator of linker histone H1. Nat Commun. 2021;12:3497 pubmed 出版商
  • 免疫细胞化学; 人类; 图 3a
  • 免疫印迹; 人类; 图 3d
Repenning A, Happel D, Bouchard C, Meixner M, Verel Yilmaz Y, Raifer H, et al. PRMT1 promotes the tumor suppressor function of p14ARF and is indicative for pancreatic cancer prognosis. EMBO J. 2021;40:e106777 pubmed 出版商
  • 免疫印迹基因敲除验证; 人类; 1:1000; 图 4j
Shi L, Magee P, Fassan M, Sahoo S, Leong H, LEE D, et al. A KRAS-responsive long non-coding RNA controls microRNA processing. Nat Commun. 2021;12:2038 pubmed 出版商
  • 免疫组化-冰冻切片; 人类; 图 1b, 1c
Klein I, Boija A, Afeyan L, Hawken S, Fan M, Dall Agnese A, et al. Partitioning of cancer therapeutics in nuclear condensates. Science. 2020;368:1386-1392 pubmed 出版商
  • 免疫细胞化学; 人类; 1:50; 图 6a
Gil L, Niño S, Chi Ahumada E, Rodríguez Leyva I, Guerrero C, Rebolledo A, et al. Perinuclear Lamin A and Nucleoplasmic Lamin B2 Characterize Two Types of Hippocampal Neurons through Alzheimer's Disease Progression. Int J Mol Sci. 2020;21: pubmed 出版商
  • 免疫印迹; 人类; 图 3e
Saini N, Sarin A. Nucleolar localization of the Notch4 intracellular domain underpins its regulation of the cellular response to genotoxic stressors. Cell Death Discov. 2020;6:7 pubmed 出版商
  • 免疫印迹; 小鼠; 1:500; 图 7d
Brody M, Vanhoutte D, Bakshi C, Liu R, Correll R, Sargent M, et al. Disruption of valosin-containing protein activity causes cardiomyopathy and reveals pleiotropic functions in cardiac homeostasis. J Biol Chem. 2019;294:8918-8929 pubmed 出版商
  • 免疫细胞化学; 人类; 1:100; 图 1f
Douet J, Corujo D, Malinverni R, Renauld J, Sansoni V, Posavec Marjanović M, et al. MacroH2A histone variants maintain nuclear organization and heterochromatin architecture. J Cell Sci. 2017;130:1570-1582 pubmed 出版商
  • 免疫印迹; 人类; 图 1a
Huang M, Garcia J, Thomas D, Zhu L, Nguyen L, Chan S, et al. Autophagy mediates proteolysis of NPM1 and HEXIM1 and sensitivity to BET inhibition in AML cells. Oncotarget. 2016;7:74917-74930 pubmed 出版商
  • 免疫印迹; 人类; 图 s1
Vickers T, Crooke S. Development of a Quantitative BRET Affinity Assay for Nucleic Acid-Protein Interactions. PLoS ONE. 2016;11:e0161930 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:5000; 图 6a
  • 免疫细胞化学; 人类; 1:500; 图 1a
  • 免疫印迹; 人类; 图 1c
Destouches D, Sader M, Terry S, Marchand C, Maillé P, Soyeux P, et al. Implication of NPM1 phosphorylation and preclinical evaluation of the nucleoprotein antagonist N6L in prostate cancer. Oncotarget. 2016;7:69397-69411 pubmed 出版商
  • 免疫印迹; 小鼠; 图 4
  • 免疫细胞化学; 人类; 1:200; 图 s2
  • 免疫印迹; 人类; 图 5
Ponti D, Bastianelli D, Rosa P, Pacini L, Ibrahim M, Rendina E, et al. The expression of B23 and EGR1 proteins is functionally linked in tumor cells under stress conditions. BMC Cell Biol. 2015;16:27 pubmed 出版商
  • 免疫印迹; 小鼠
Tancioni I, Miller N, Uryu S, Lawson C, Jean C, Chen X, et al. FAK activity protects nucleostemin in facilitating breast cancer spheroid and tumor growth. Breast Cancer Res. 2015;17:47 pubmed 出版商
  • 其他; 人类; 图 2
Jørgensen M, Bæk R, Varming K. Potentials and capabilities of the Extracellular Vesicle (EV) Array. J Extracell Vesicles. 2015;4:26048 pubmed 出版商
  • 免疫沉淀; 人类; 图 1a
  • 免疫细胞化学; 人类; 图 s1
  • 免疫印迹; 人类; 图 6a
Arnoldo L, Sgarra R, Chiefari E, Iiritano S, Arcidiacono B, Pegoraro S, et al. A novel mechanism of post-translational modulation of HMGA functions by the histone chaperone nucleophosmin. Sci Rep. 2015;5:8552 pubmed 出版商
  • 免疫沉淀; 人类; 图 6c
  • 免疫印迹; 人类; 1:3000; 图 7g
Wang L, Liu R, Ye P, Wong C, Chen G, Zhou P, et al. Intracellular CD24 disrupts the ARF-NPM interaction and enables mutational and viral oncogene-mediated p53 inactivation. Nat Commun. 2015;6:5909 pubmed 出版商
  • 免疫细胞化学; 人类
Khalouei S, Chow A, Brown I. Localization of heat shock protein HSPA6 (HSP70B') to sites of transcription in cultured differentiated human neuronal cells following thermal stress. J Neurochem. 2014;131:743-54 pubmed 出版商
  • 免疫印迹; 人类; 图 2
Hamilton G, Abraham A, Morton J, Sampson O, Pefani D, Khoronenkova S, et al. AKT regulates NPM dependent ARF localization and p53mut stability in tumors. Oncotarget. 2014;5:6142-67 pubmed
  • 免疫细胞化学; 小鼠
Lührig S, Siamishi I, Tesmer Wolf M, Zechner U, Engel W, Nolte J. Lrrc34, a novel nucleolar protein, interacts with npm1 and ncl and has an impact on pluripotent stem cells. Stem Cells Dev. 2014;23:2862-74 pubmed 出版商
Fang H, Bonora G, Lewandowski J, Thakur J, Filippova G, Henikoff S, et al. Trans- and cis-acting effects of Firre on epigenetic features of the inactive X chromosome. Nat Commun. 2020;11:6053 pubmed 出版商
Zhang W, Cheng W, Parlato R, Guo X, Cui X, Dai C, et al. Nucleolar stress induces a senescence-like phenotype in smooth muscle cells and promotes development of vascular degeneration. Aging (Albany NY). 2020;12:22174-22198 pubmed 出版商
Mun K, Punga T. Cellular Zinc Finger Protein 622 Hinders Human Adenovirus Lytic Growth and Limits Binding of the Viral pVII Protein to Virus DNA. J Virol. 2019;93: pubmed 出版商
Zhang J, Zhang Y, Zhao L, Guo J, Yu J, Ji S, et al. Mammalian nucleolar protein DCAF13 is essential for ovarian follicle maintenance and oocyte growth by mediating rRNA processing. Cell Death Differ. 2019;26:1251-1266 pubmed 出版商
Mata Garrido J, Tapia O, Casafont I, Berciano M, Cuadrado A, Lafarga M. Persistent accumulation of unrepaired DNA damage in rat cortical neurons: nuclear organization and ChIP-seq analysis of damaged DNA. Acta Neuropathol Commun. 2018;6:68 pubmed 出版商
Dumbovic G, Biayna J, Banús J, Samuelsson J, Roth A, Diederichs S, et al. A novel long non-coding RNA from NBL2 pericentromeric macrosatellite forms a perinucleolar aggregate structure in colon cancer. Nucleic Acids Res. 2018;46:5504-5524 pubmed 出版商
Mizielinska S, Ridler C, Balendra R, Thoeng A, Woodling N, Grässer F, et al. Bidirectional nucleolar dysfunction in C9orf72 frontotemporal lobar degeneration. Acta Neuropathol Commun. 2017;5:29 pubmed 出版商
Cheung D, Ho S, Lau K, Jin R, Wang Y, Kung H, et al. Nucleophosmin Interacts with PIN2/TERF1-interacting Telomerase Inhibitor 1 (PinX1) and Attenuates the PinX1 Inhibition on Telomerase Activity. Sci Rep. 2017;7:43650 pubmed 出版商
Ponti D, Bellenchi G, Puca R, Bastianelli D, Maroder M, Ragona G, et al. The transcription factor EGR1 localizes to the nucleolus and is linked to suppression of ribosomal precursor synthesis. PLoS ONE. 2014;9:e96037 pubmed 出版商
Kind J, van Steensel B. Stochastic genome-nuclear lamina interactions: modulating roles of Lamin A and BAF. Nucleus. 2014;5:124-30 pubmed 出版商
Ding A, Zhao W, Shi X, Yao R, Zhou F, Yue L, et al. Impact of NPM, TFF3 and TACC1 on the prognosis of patients with primary gastric cancer. PLoS ONE. 2013;8:e82136 pubmed 出版商
Cong R, Das S, Douet J, Wong J, Buschbeck M, Mongelard F, et al. macroH2A1 histone variant represses rDNA transcription. Nucleic Acids Res. 2014;42:181-92 pubmed 出版商
Lam L, Aktary Z, Bishay M, Werkman C, Kuo C, Heacock M, et al. Regulation of subcellular distribution and oncogenic potential of nucleophosmin by plakoglobin. Oncogenesis. 2012;1:e4 pubmed 出版商
Cong R, Das S, Ugrinova I, Kumar S, Mongelard F, Wong J, et al. Interaction of nucleolin with ribosomal RNA genes and its role in RNA polymerase I transcription. Nucleic Acids Res. 2012;40:9441-54 pubmed 出版商
Kalt I, Levy A, Borodianskiy Shteinberg T, Sarid R. Nucleolar localization of GLTSCR2/PICT-1 is mediated by multiple unique nucleolar localization sequences. PLoS ONE. 2012;7:e30825 pubmed 出版商
Johansson H, Simonsson S. Core transcription factors, Oct4, Sox2 and Nanog, individually form complexes with nucleophosmin (Npm1) to control embryonic stem (ES) cell fate determination. Aging (Albany NY). 2010;2:815-22 pubmed
Borg J, Papadopoulos P, Georgitsi M, Gutierrez L, Grech G, Fanis P, et al. Haploinsufficiency for the erythroid transcription factor KLF1 causes hereditary persistence of fetal hemoglobin. Nat Genet. 2010;42:801-5 pubmed 出版商
Herkert B, Dwertmann A, Herold S, Abed M, Naud J, Finkernagel F, et al. The Arf tumor suppressor protein inhibits Miz1 to suppress cell adhesion and induce apoptosis. J Cell Biol. 2010;188:905-18 pubmed 出版商
Song B, Lee S, Kim S, Kim J, Park J, Kim C, et al. Nucleologenesis and embryonic genome activation are defective in interspecies cloned embryos between bovine ooplasm and rhesus monkey somatic cells. BMC Dev Biol. 2009;9:44 pubmed 出版商
产品信息
目录号 :
ab10530
ItemName :
Anti-Nucleophosmin antibody [FC82291]
产品类型 :
一抗
宿主物种 :
小鼠
克隆性 :
单克隆
共轭标签 :
Not Conjugated
抗原修饰 :
No Modifications
克隆名称 :
FC82291
规格 :
100微升
物种摘要 :
AGMk, Cow, Dnk, Dog, Hm, Hu, Ms, Rat
用途 :
酶联免疫吸附测定, 免疫细胞化学/IF, 免疫组化-P, 免疫沉淀, 免疫印迹
公司信息
艾博抗(上海)贸易有限公司
上海市浦东新区伽利略路338号5幢4层5401室
cn.technical@abcam.com
http://www.abcam.cn
400-628-6880 86-21-5110 5938
公司总部: 英国
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