出版应用/物种/样本/稀释 | 参考文献 |
---|
| Leon K, Buj R, Lesko E, Dahl E, Chen C, Tangudu N, et al. DOT1L modulates the senescence-associated secretory phenotype through epigenetic regulation of IL1A. J Cell Biol. 2021;220: pubmed 出版商
|
| Buj R, Leon K, Anguelov M, Aird K. Suppression of p16 alleviates the senescence-associated secretory phenotype. Aging (Albany NY). 2021;13:3290-3312 pubmed 出版商
|
| Karnan S, Ota A, Murakami H, Rahman M, Hasan M, Wahiduzzaman M, et al. Identification of CD24 as a potential diagnostic and therapeutic target for malignant pleural mesothelioma. Cell Death Discov. 2020;6:127 pubmed 出版商
|
| Varela Eirin M, Carpintero Fernández P, Sánchez Temprano A, Varela Vazquez A, Paíno C, Casado Diaz A, et al. Senolytic activity of small molecular polyphenols from olive restores chondrocyte redifferentiation and promotes a pro-regenerative environment in osteoarthritis. Aging (Albany NY). 2020;12:15882-15905 pubmed 出版商
|
| Shao Q, Esseltine J, Huang T, Novielli Kuntz N, Ching J, SAMPSON J, et al. Connexin43 is Dispensable for Early Stage Human Mesenchymal Stem Cell Adipogenic Differentiation But is Protective against Cell Senescence. Biomolecules. 2019;9: pubmed 出版商
|
- 免疫组化-石蜡切片; 人类; 1:200; 图 1d
- 免疫印迹; 人类; 1:1000; 图 1g
| Gal H, Lysenko M, Stroganov S, Vadai E, Youssef S, Tzadikevitch Geffen K, et al. Molecular pathways of senescence regulate placental structure and function. EMBO J. 2019;38:e100849 pubmed 出版商
|
| Wang J, Liu Y, Liu Y, Zheng S, Wang X, Zhao J, et al. Time-resolved protein activation by proximal decaging in living systems. Nature. 2019;569:509-513 pubmed 出版商
|
| He M, Chaurushiya M, Webster J, Kummerfeld S, Reja R, Chaudhuri S, et al. Intrinsic apoptosis shapes the tumor spectrum linked to inactivation of the deubiquitinase BAP1. Science. 2019;364:283-285 pubmed 出版商
|
| Liang C, Ma Y, Yong L, Yang C, Wang P, Liu X, et al. Y-box binding protein-1 promotes tumorigenesis and progression via the epidermal growth factor receptor/AKT pathway in spinal chordoma. Cancer Sci. 2019;110:166-179 pubmed 出版商
|
| Zhang Y, Wang J, Huang W, Cai J, Ba J, Wang Y, et al. Nuclear Nestin deficiency drives tumor senescence via lamin A/C-dependent nuclear deformation. Nat Commun. 2018;9:3613 pubmed 出版商
|
| Laporte A, Barrott J, Yao R, Poulin N, Brodin B, Jones K, et al. HDAC and Proteasome Inhibitors Synergize to Activate Pro-Apoptotic Factors in Synovial Sarcoma. PLoS ONE. 2017;12:e0169407 pubmed 出版商
|
| Lee J, Yu K, Kim H, Kang I, Kim J, Lee B, et al. BMI1 inhibits senescence and enhances the immunomodulatory properties of human mesenchymal stem cells via the direct suppression of MKP-1/DUSP1. Aging (Albany NY). 2016;8:1670-89 pubmed 出版商
|
| Fafián Labora J, O Loghlen A. NF-κB/IKK activation by small extracellular vesicles within the SASP. Aging Cell. 2021;20:e13426 pubmed 出版商
|
| Zhang C, Zhang X, Huang L, Guan Y, Huang X, Tian X, et al. ATF3 drives senescence by reconstructing accessible chromatin profiles. Aging Cell. 2021;20:e13315 pubmed 出版商
|
| Wu J, Cheng I, Saovieng S, Jean W, Kao C, Liu Y, et al. Aerobic exercise induces tumor suppressor p16INK4a expression of endothelial progenitor cells in human skeletal muscle. Aging (Albany NY). 2020;12:20226-20234 pubmed 出版商
|
| Coryell P, Goraya S, Griffin K, Redick M, Sisk S, Purvis J. Autophagy regulates the localization and degradation of p16INK4a. Aging Cell. 2020;19:e13171 pubmed 出版商
|
| Wei F, Wang A, Wang Q, Han W, Rong R, Wang L, et al. Plasma endothelial cells-derived extracellular vesicles promote wound healing in diabetes through YAP and the PI3K/Akt/mTOR pathway. Aging (Albany NY). 2020;12:12002-12018 pubmed 出版商
|
| Xie J, Lin J, Wei M, Teng Y, He Q, Yang G, et al. Sustained Akt signaling in articular chondrocytes causes osteoarthritis via oxidative stress-induced senescence in mice. Bone Res. 2019;7:23 pubmed 出版商
|
| Lionarons D, Hancock D, Rana S, East P, Moore C, Murillo M, et al. RAC1P29S Induces a Mesenchymal Phenotypic Switch via Serum Response Factor to Promote Melanoma Development and Therapy Resistance. Cancer Cell. 2019;: pubmed 出版商
|
| Borghesan M, Fafián Labora J, Eleftheriadou O, Carpintero Fernández P, Pàez Ribes M, Vizcay Barrena G, et al. Small Extracellular Vesicles Are Key Regulators of Non-cell Autonomous Intercellular Communication in Senescence via the Interferon Protein IFITM3. Cell Rep. 2019;27:3956-3971.e6 pubmed 出版商
|
| Gong C, Pan W, Hu W, Chen L. Bone morphogenetic protein-7 retards cell subculture-induced senescence of human nucleus pulposus cells through activating the PI3K/Akt pathway. Biosci Rep. 2019;39: pubmed 出版商
|
| Varela Eirin M, Varela Vazquez A, Guitián Caamaño A, Paíno C, Mato V, Largo R, et al. Targeting of chondrocyte plasticity via connexin43 modulation attenuates cellular senescence and fosters a pro-regenerative environment in osteoarthritis. Cell Death Dis. 2018;9:1166 pubmed 出版商
|
| Li Z, Liu T, Ma J, Guo Q, Ma L, Lv Q, et al. TGF-β induces corneal endothelial senescence via increase of mitochondrial reactive oxygen species in chronic corneal allograft failure. Aging (Albany NY). 2018;10:3474-3485 pubmed 出版商
|
| Gao X, Lu A, Tang Y, Schneppendahl J, Liebowitz A, Scibetta A, et al. Influences of donor and host age on human muscle-derived stem cell-mediated bone regeneration. Stem Cell Res Ther. 2018;9:316 pubmed 出版商
|
| Kumar B, Prasad M, Bhat Nakshatri P, Anjanappa M, Kalra M, Marino N, et al. Normal Breast-Derived Epithelial Cells with Luminal and Intrinsic Subtype-Enriched Gene Expression Document Interindividual Differences in Their Differentiation Cascade. Cancer Res. 2018;78:5107-5123 pubmed 出版商
|
| Yang C, Jiao Y, Wei B, Yang Z, Wu J, Jensen J, et al. Aged cells in human skeletal muscle after resistance exercise. Aging (Albany NY). 2018;10:1356-1365 pubmed 出版商
|
| Rahman T, Ullah K, Guo M, Pan H, Liu J, Ren J, et al. Androgen-induced alterations in endometrial proteins crucial in recurrent miscarriages. Oncotarget. 2018;9:24627-24641 pubmed 出版商
|
| Lee J, Yu K, Lee B, Kang I, Kim J, Jung E, et al. GATA4-dependent regulation of the secretory phenotype via MCP-1 underlies lamin A-mediated human mesenchymal stem cell aging. Exp Mol Med. 2018;50:63 pubmed 出版商
|
| Li X, Zhang Z, Zhang Y, Cao Y, Wei H, Wu Z. Upregulation of lactate-inducible snail protein suppresses oncogene-mediated senescence through p16INK4a inactivation. J Exp Clin Cancer Res. 2018;37:39 pubmed 出版商
|
| Al Khalaf H, Amir M, Al Mohanna F, Tulbah A, Al Sayed A, Aboussekhra A. Obesity and p16INK4A Downregulation Activate Breast Adipocytes and Promote Their Protumorigenicity. Mol Cell Biol. 2017;37: pubmed 出版商
|
| Yosef R, Pilpel N, Papismadov N, Gal H, Ovadya Y, Vadai E, et al. p21 maintains senescent cell viability under persistent DNA damage response by restraining JNK and caspase signaling. EMBO J. 2017;36:2280-2295 pubmed 出版商
|
| Bellio M, Rodrigues C, Landin A, Hatzistergos K, Kuznetsov J, Florea V, et al. Physiological and hypoxic oxygen concentration differentially regulates human c-Kit+ cardiac stem cell proliferation and migration. Am J Physiol Heart Circ Physiol. 2016;311:H1509-H1519 pubmed 出版商
|