产品简要
公司名称 :
艾博抗(上海)贸易有限公司
其他品牌 :
Epitomics, Ascent Scientific, MitoSciences
产品类型 :
抗体
产品名称 :
Anti-SQSTM1 / p62 antibody [EPR4844] - Autophagosome Marker
目录 :
ab109012
规格 :
10微升, 100微升
克隆性 :
单克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
克隆名称 :
EPR4844
反应物种 :
人类, 小鼠, 大鼠, 斑马鱼
应用 :
免疫印迹, 免疫细胞化学, 流式细胞仪, 其他, 免疫印迹基因敲除验证
文章摘录数: 43
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 小鼠; 图 4a
Cao Y, Li Q, Yang Y, Ke Z, Chen S, Li M, et al. Cardioprotective Effect of Stem-Leaf Saponins From Panax notoginseng on Mice With Sleep Derivation by Inhibiting Abnormal Autophagy Through PI3K/Akt/mTOR Pathway. Front Cardiovasc Med. 2021;8:694219 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 5g
Kremer D, Nelson B, Lin L, Yarosz E, Halbrook C, Kerk S, et al. GOT1 inhibition promotes pancreatic cancer cell death by ferroptosis. Nat Commun. 2021;12:4860 pubmed 出版商
  • 免疫印迹; 小鼠; 1:2000; 图 6a
Xiao J, Tu B, Zhou X, Jiang X, Xu G, Zhang J, et al. Autophagy deficiency exacerbates acute lung injury induced by copper oxide nanoparticles. J Nanobiotechnology. 2021;19:162 pubmed 出版商
  • 免疫印迹基因敲除验证; 人类; 1:20,000; 图 4d
  • 免疫印迹; 人类; 1:20,000; 图 1d
Yu F, Ma R, Liu C, Zhang L, Feng K, Wang M, et al. SQSTM1/p62 Promotes Cell Growth and Triggers Autophagy in Papillary Thyroid Cancer by Regulating the AKT/AMPK/mTOR Signaling Pathway. Front Oncol. 2021;11:638701 pubmed 出版商
  • 免疫印迹; 人类; 图 4b
Hua Y, Zhang K, Sheng J, Ning Z, Li Y, Shi W, et al. NUCB1 Suppresses Growth and Shows Additive Effects With Gemcitabine in Pancreatic Ductal Adenocarcinoma via the Unfolded Protein Response. Front Cell Dev Biol. 2021;9:641836 pubmed 出版商
  • 免疫细胞化学; 人类; 1:200; 图 1k
  • 免疫印迹; 人类; 1:2000; 图 1l
Yoon M, Choi B, Kim E, Ohk J, Yang C, Choi Y, et al. UXT chaperone prevents proteotoxicity by acting as an autophagy adaptor for p62-dependent aggrephagy. Nat Commun. 2021;12:1955 pubmed 出版商
  • 其他; 小鼠; 图 5
Budzik J, Swaney D, Jimenez Morales D, Johnson J, Garelis N, Repasy T, et al. Dynamic post-translational modification profiling of Mycobacterium tuberculosis-infected primary macrophages. elife. 2020;9: pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 6e
Zhang S, Hu L, Jiang J, Li H, Wu Q, Ooi K, et al. HMGB1/RAGE axis mediates stress-induced RVLM neuroinflammation in mice via impairing mitophagy flux in microglia. J Neuroinflammation. 2020;17:15 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 4d
Wang X, Zhao L, Ajay A, Jiao B, Zhang X, Wang C, et al. QiDiTangShen Granules Activate Renal Nutrient-Sensing Associated Autophagy in db/db Mice. Front Physiol. 2019;10:1224 pubmed 出版商
  • 免疫细胞化学; 人类; 图 1f
  • 免疫印迹; 人类; 图 1g
Pan H, Alamri A, Valapala M. Nutrient deprivation and lysosomal stress induce activation of TFEB in retinal pigment epithelial cells. Cell Mol Biol Lett. 2019;24:33 pubmed 出版商
  • 免疫印迹; 人类; 图 7k
Jeppesen D, Fenix A, Franklin J, Higginbotham J, Zhang Q, Zimmerman L, et al. Reassessment of Exosome Composition. Cell. 2019;177:428-445.e18 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 1b, e5b
  • 免疫印迹; 大鼠; 1:1000; 图 2b
Ranek M, Kokkonen Simon K, Chen A, Dunkerly Eyring B, Vera M, Oeing C, et al. PKG1-modified TSC2 regulates mTORC1 activity to counter adverse cardiac stress. Nature. 2019;566:264-269 pubmed 出版商
  • 免疫印迹; 小鼠; 1:10,000; 图 2a
Mu Y, Yan W, Yin T, Zhang Y, Li J, Yang J. Diet-induced obesity impairs spermatogenesis: a potential role for autophagy. Sci Rep. 2017;7:43475 pubmed 出版商
  • 免疫印迹; 小鼠; 图 7b
Liu J, Wang H, Gu J, Deng T, Yuan Z, Hu B, et al. BECN1-dependent CASP2 incomplete autophagy induction by binding to rabies virus phosphoprotein. Autophagy. 2017;13:739-753 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 6b
Nalbandian A, Khan A, Srivastava R, Llewellyn K, Tan B, Shukr N, et al. Activation of the NLRP3 Inflammasome Is Associated with Valosin-Containing Protein Myopathy. Inflammation. 2017;40:21-41 pubmed 出版商
  • 免疫印迹; 斑马鱼; 1:2000; 图 5
Bühler A, Kustermann M, Bummer T, Rottbauer W, Sandri M, Just S. Atrogin-1 Deficiency Leads to Myopathy and Heart Failure in Zebrafish. Int J Mol Sci. 2016;17: pubmed 出版商
  • 免疫印迹; 人类; 图 3
Gentry E, Henderson B, Arrant A, Gearing M, Feng Y, Riddle N, et al. Rho Kinase Inhibition as a Therapeutic for Progressive Supranuclear Palsy and Corticobasal Degeneration. J Neurosci. 2016;36:1316-23 pubmed 出版商
  • 免疫印迹; 大鼠
  • 免疫细胞化学; 人类
Zhang L, Wang H, Ding K, Xu J. FTY720 induces autophagy-related apoptosis and necroptosis in human glioblastoma cells. Toxicol Lett. 2015;236:43-59 pubmed 出版商
  • 免疫印迹; 人类; 图 1c
Ulasov I, Shah N, Kaverina N, Lee H, Lin B, Lieber A, et al. Tamoxifen improves cytopathic effect of oncolytic adenovirus in primary glioblastoma cells mediated through autophagy. Oncotarget. 2015;6:3977-87 pubmed
  • 免疫印迹; 人类; 1:3000
Meng G, Xia M, Wang D, Chen A, Wang Y, Wang H, et al. Mitophagy promotes replication of oncolytic Newcastle disease virus by blocking intrinsic apoptosis in lung cancer cells. Oncotarget. 2014;5:6365-74 pubmed
  • 免疫印迹; 人类; 1:5,000
Xia M, Gonzalez P, Li C, Meng G, Jiang A, Wang H, et al. Mitophagy enhances oncolytic measles virus replication by mitigating DDX58/RIG-I-like receptor signaling. J Virol. 2014;88:5152-64 pubmed 出版商
Wang J, Liu B, Xu Y, Yang M, Wang C, Song M, et al. Activation of CREB-mediated autophagy by thioperamide ameliorates β-amyloid pathology and cognition in Alzheimer's disease. Aging Cell. 2021;20:e13333 pubmed 出版商
Qian F, Guo Y, Zu J, Zhang J, Zheng Y, Abdoulaye I, et al. A novel recessive mutation affecting DNAJB6a causes myofibrillar myopathy. Acta Neuropathol Commun. 2021;9:23 pubmed 出版商
Su Q, Li T, He P, Lu X, Yu Q, Gao Q, et al. Trichostatin A ameliorates Alzheimer's disease-related pathology and cognitive deficits by increasing albumin expression and Aβ clearance in APP/PS1 mice. Alzheimers Res Ther. 2021;13:7 pubmed 出版商
Long C, Cen S, Zhong Z, Zhou C, Zhong G. FOXO3 is targeted by miR-223-3p and promotes osteogenic differentiation of bone marrow mesenchymal stem cells by enhancing autophagy. Hum Cell. 2021;34:14-27 pubmed 出版商
Goljanek Whysall K, Soriano Arroquia A, McCormick R, Chinda C, McDonagh B. miR-181a regulates p62/SQSTM1, parkin, and protein DJ-1 promoting mitochondrial dynamics in skeletal muscle aging. Aging Cell. 2020;19:e13140 pubmed 出版商
Zou L, Lei H, Shen J, Liu X, Zhang X, Wu L, et al. HO-1 induced autophagy protects against IL-1 β-mediated apoptosis in human nucleus pulposus cells by inhibiting NF-κB. Aging (Albany NY). 2020;12:2440-2452 pubmed 出版商
Dannheisig D, Beck E, Calzia E, Walther P, Behrends C, Pfister A. Loss of Peter Pan (PPAN) Affects Mitochondrial Homeostasis and Autophagic Flux. Cells. 2019;8: pubmed 出版商
Zhang X, Kumstel S, Jiang K, Meng S, Gong P, Vollmar B, et al. LW6 enhances chemosensitivity to gemcitabine and inhibits autophagic flux in pancreatic cancer. J Adv Res. 2019;20:9-21 pubmed 出版商
Zhuang H, Wu F, Wei W, Dang Y, Yang B, Ma X, et al. Glycine decarboxylase induces autophagy and is downregulated by miRNA-30d-5p in hepatocellular carcinoma. Cell Death Dis. 2019;10:192 pubmed 出版商
Zhang P, Guan Y, Chen J, Li X, McConnell B, Zhou W, et al. Contribution of p62/SQSTM1 to PDGF-BB-induced myofibroblast-like phenotypic transition in vascular smooth muscle cells lacking Smpd1 gene. Cell Death Dis. 2018;9:1145 pubmed 出版商
Peng S, Xu L, Che X, Xiao Q, Pu J, Shao Q, et al. Atorvastatin Inhibits Inflammatory Response, Attenuates Lipid Deposition, and Improves the Stability of Vulnerable Atherosclerotic Plaques by Modulating Autophagy. Front Pharmacol. 2018;9:438 pubmed 出版商
Sinkevicius K, Morrison T, Kulkarni P, Caffrey Cagliostro M, Iriah S, Malmberg S, et al. RNaseT2 knockout rats exhibit hippocampal neuropathology and deficits in memory. Dis Model Mech. 2018;11: pubmed 出版商
Sun Y, Liu M, Lei X, YU X. SFTS phlebovirus promotes LC3-II accumulation and nonstructural protein of SFTS phlebovirus co-localizes with autophagy proteins. Sci Rep. 2018;8:5287 pubmed 出版商
Flores Costa R, Alcaraz Quiles J, Titos E, López Vicario C, Casulleras M, Duran Güell M, et al. The soluble guanylate cyclase stimulator IW-1973 prevents inflammation and fibrosis in experimental non-alcoholic steatohepatitis. Br J Pharmacol. 2018;175:953-967 pubmed 出版商
Tang F, Hu P, Yang Z, Xue C, Gong J, Sun S, et al. SBI0206965, a novel inhibitor of Ulk1, suppresses non-small cell lung cancer cell growth by modulating both autophagy and apoptosis pathways. Oncol Rep. 2017;37:3449-3458 pubmed 出版商
Lu K, Alcivar A, Ma J, Foo T, Zywea S, Mahdi A, et al. NRF2 Induction Supporting Breast Cancer Cell Survival Is Enabled by Oxidative Stress-Induced DPP3-KEAP1 Interaction. Cancer Res. 2017;77:2881-2892 pubmed 出版商
Matos L, Gouveia A, Almeida H. Resveratrol Attenuates Copper-Induced Senescence by Improving Cellular Proteostasis. Oxid Med Cell Longev. 2017;2017:3793817 pubmed 出版商
Perez M, Peinado Serrano J, García Heredia J, Felipe Abrio I, Tous C, Ferrer I, et al. Efficacy of bortezomib in sarcomas with high levels of MAP17 (PDZK1IP1). Oncotarget. 2016;7:67033-67046 pubmed 出版商
Hu B, Zhang Y, Jia L, Wu H, Fan C, Sun Y, et al. Binding of the pathogen receptor HSP90AA1 to avibirnavirus VP2 induces autophagy by inactivating the AKT-MTOR pathway. Autophagy. 2015;11:503-15 pubmed 出版商
Xiong Y, Yepuri G, Forbiteh M, Yu Y, Montani J, Yang Z, et al. ARG2 impairs endothelial autophagy through regulation of MTOR and PRKAA/AMPK signaling in advanced atherosclerosis. Autophagy. 2014;10:2223-38 pubmed 出版商
Xia M, Meng G, Jiang A, Chen A, Dahlhaus M, Gonzalez P, et al. Mitophagy switches cell death from apoptosis to necrosis in NSCLC cells treated with oncolytic measles virus. Oncotarget. 2014;5:3907-18 pubmed
Meng G, Xia M, Xu C, Yuan D, Schnurr M, Wei J. Multifunctional antitumor molecule 5'-triphosphate siRNA combining glutaminase silencing and RIG-I activation. Int J Cancer. 2014;134:1958-71 pubmed 出版商
产品信息
目录号 :
ab109012
ItemName :
Anti-SQSTM1 / p62 antibody [EPR4844] - Autophagosome Marker
类别 :
抗体
宿主 :
克隆性 :
单克隆
共轭标签 :
未共轭
克隆名称 :
EPR4844
规格 :
10微升, 100微升
物种摘要 :
Hu, Ms, Rat
应用摘要 :
Flow Cyt, ICC/IF, WB
公司信息
艾博抗(上海)贸易有限公司
上海市浦东新区伽利略路338号5幢4层5401室
cn.technical@abcam.com
http://www.abcam.cn
400-628-6880 86-21-5110 5938
公司总部: 英国
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