产品简要
公司名称 :
艾博抗(上海)贸易有限公司
其他品牌 :
Epitomics, Ascent Scientific, MitoSciences
产品类型 :
抗体
产品名称 :
抗p21抗体[EPR3993]
目录 :
ab109199
规格 :
10微升, 100微升
克隆性 :
单克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
克隆名称 :
EPR3993
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 流式细胞仪, 免疫组化-石蜡切片, 免疫组化-冰冻切片
文章摘录数: 46
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 大鼠; 图 s4b
Song L, Tian X, Schekman R. Extracellular vesicles from neurons promote neural induction of stem cells through cyclin D1. J Cell Biol. 2021;220: pubmed 出版商
  • 免疫印迹; 小鼠; 图 4b
Lee H, Donati A, Feliers D, Sun Y, Ding Y, Madesh M, et al. Chloride channel accessory 1 integrates chloride channel activity and mTORC1 in aging-related kidney injury. Aging Cell. 2021;20:e13407 pubmed 出版商
  • 免疫印迹; 小鼠; 图 1j
Kim C, Jin J, Ye Z, Jadhav R, Gustafson C, Hu B, et al. Histone deficiency and accelerated replication stress in T cell aging. J Clin Invest. 2021;131: pubmed 出版商
  • 免疫印迹; 大鼠; 1:1000; 图 2g
  • 免疫组化-石蜡切片; 小鼠; 1:50; 图 1c
  • 免疫印迹; 小鼠; 1:1000; 图 1e
Huang P, Bai L, Liu L, Fu J, Wu K, Liu H, et al. Redd1 knockdown prevents doxorubicin-induced cardiac senescence. Aging (Albany NY). 2021;13:13788-13806 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 3f
Morimune T, Tano A, Tanaka Y, Yukiue H, Yamamoto T, Tooyama I, et al. Gm14230 controls Tbc1d24 cytoophidia and neuronal cellular juvenescence. PLoS ONE. 2021;16:e0248517 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 3a
Li W, Zheng J, Zhao G, Lyu C, Lu W. Overexpression of DSCR1 prevents proliferation and predicts favorable prognosis in colorectal cancer patients. World J Surg Oncol. 2021;19:100 pubmed 出版商
  • 免疫印迹; 人类; 1:1000
Buj R, Leon K, Anguelov M, Aird K. Suppression of p16 alleviates the senescence-associated secretory phenotype. Aging (Albany NY). 2021;13:3290-3312 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 2c
Wueest S, Lucchini F, Haim Y, Rudich A, Konrad D. Depletion of ASK1 blunts stress-induced senescence in adipocytes. Adipocyte. 2020;9:535-541 pubmed 出版商
  • 流式细胞仪; 人类; 1:200; 图 s5c
  • 免疫印迹; 人类; 1:1000; 图 s2b
Zatulovskiy E, Zhang S, Berenson D, Topacio B, Skotheim J. Cell growth dilutes the cell cycle inhibitor Rb to trigger cell division. Science. 2020;369:466-471 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 3c
Xie X, Wang Y, Xia Y, Mao Y. Overexpressed vascular endothelial growth factor in adipose derived stem cells attenuates fibroblasts and skin injuries by ultraviolet radiation. Biosci Rep. 2019;39: pubmed 出版商
  • 免疫印迹; 大鼠; 1:1000; 图 5b
Luo X, Jiang X, Li J, Bai Y, Li Z, Wei P, et al. Insulin-like growth factor-1 attenuates oxidative stress-induced hepatocyte premature senescence in liver fibrogenesis via regulating nuclear p53-progerin interaction. Cell Death Dis. 2019;10:451 pubmed 出版商
  • 免疫印迹; 人类; 1:1500; 图 2b
  • 免疫印迹; 大鼠; 图 2b
Liu X, Zhao P, Wang X, Wang L, Zhu Y, Song Y, et al. Celastrol mediates autophagy and apoptosis via the ROS/JNK and Akt/mTOR signaling pathways in glioma cells. J Exp Clin Cancer Res. 2019;38:184 pubmed 出版商
  • 免疫印迹; 大鼠; 图 1b
Zhang X, Qin Q, Dai H, Cai S, Zhou C, Guan J. Emodin protects H9c2 cells from hypoxia-induced injury by up-regulating miR-138 expression. Braz J Med Biol Res. 2019;52:e7994 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1:200; 图 2a
  • 免疫细胞化学; 小鼠; 1:200; 图 3c
  • 免疫印迹; 小鼠; 图 3a
Feng F, Wang Z, Li R, Wu Q, Gu C, Xu Y, et al. Citrus alkaline extracts prevent fibroblast senescence to ameliorate pulmonary fibrosis via activation of COX-2. Biomed Pharmacother. 2019;112:108669 pubmed 出版商
  • 免疫印迹; 大鼠; 1:1000; 图 6c
Jin L, Lu J, Gao J. Silencing SUMO2 promotes protection against degradation and apoptosis of nucleus pulposus cells through p53 signaling pathway in intervertebral disc degeneration. Biosci Rep. 2018;38: pubmed 出版商
  • 免疫印迹; 小鼠; 图 6c
Lee C, Hsieh T. Wuho/WDR4 deficiency inhibits cell proliferation and induces apoptosis via DNA damage in mouse embryonic fibroblasts. Cell Signal. 2018;47:16-26 pubmed 出版商
  • 免疫组化; 小鼠; 1:500; 图 8f
Chen K, Dai H, Yuan J, Chen J, Lin L, Zhang W, et al. Optineurin-mediated mitophagy protects renal tubular epithelial cells against accelerated senescence in diabetic nephropathy. Cell Death Dis. 2018;9:105 pubmed 出版商
  • 免疫印迹; 人类; 图 3g
Chavali P, Stojic L, Meredith L, Joseph N, Nahorski M, Sanford T, et al. Neurodevelopmental protein Musashi-1 interacts with the Zika genome and promotes viral replication. Science. 2017;357:83-88 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 4f
Song X, Narzt M, Nagelreiter I, Hohensinner P, Terlecki Zaniewicz L, Tschachler E, et al. Autophagy deficient keratinocytes display increased DNA damage, senescence and aberrant lipid composition after oxidative stress in vitro and in vivo. Redox Biol. 2017;11:219-230 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 s1
Chen P, Qin L, Li G, Tellides G, Simons M. Fibroblast growth factor (FGF) signaling regulates transforming growth factor beta (TGF?)-dependent smooth muscle cell phenotype modulation. Sci Rep. 2016;6:33407 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 3b
Anderson K, Russell A, Foletta V. NDRG2 promotes myoblast proliferation and caspase 3/7 activities during differentiation, and attenuates hydrogen peroxide - But not palmitate-induced toxicity. FEBS Open Bio. 2015;5:668-81 pubmed 出版商
  • 免疫印迹; 人类; 1:2000; 图 1b
Deben C, Wouters A, Op de Beeck K, Van den Bossche J, Jacobs J, Zwaenepoel K, et al. The MDM2-inhibitor Nutlin-3 synergizes with cisplatin to induce p53 dependent tumor cell apoptosis in non-small cell lung cancer. Oncotarget. 2015;6:22666-79 pubmed
  • 免疫印迹; 小鼠
Beier J, Jokinen J, Holz G, Whang P, Martin A, Warner N, et al. Novel mechanism of arenavirus-induced liver pathology. PLoS ONE. 2015;10:e0122839 pubmed 出版商
Chen Z, Xiong L, Jin H, Yu J, Li X, Fu H, et al. Advanced maternal age causes premature placental senescence and malformation via dysregulated α-Klotho expression in trophoblasts. Aging Cell. 2021;20:e13417 pubmed 出版商
Liu X, Chen A, Liang Q, Yang X, Dong Q, Fu M, et al. Spermidine inhibits vascular calcification in chronic kidney disease through modulation of SIRT1 signaling pathway. Aging Cell. 2021;20:e13377 pubmed 出版商
Thangaraj A, Chivero E, Tripathi A, Singh S, Niu F, Guo M, et al. HIV TAT-mediated microglial senescence: Role of SIRT3-dependent mitochondrial oxidative stress. Redox Biol. 2021;40:101843 pubmed 出版商
Chen Y, Zhang L, Ren J, Zhang Y, Wu N, Jia M, et al. Intermedin1-53 attenuates aging-associated vascular calcification in rats by upregulating sirtuin 1. Aging (Albany NY). 2020;12:5651-5674 pubmed 出版商
Hong Y, He H, Jiang G, Zhang H, Tao W, Ding Y, et al. miR-155-5p inhibition rejuvenates aged mesenchymal stem cells and enhances cardioprotection following infarction. Aging Cell. 2020;19:e13128 pubmed 出版商
Zhang Y, Zhu W, He H, Fan B, Deng R, Hong Y, et al. Macrophage migration inhibitory factor rejuvenates aged human mesenchymal stem cells and improves myocardial repair. Aging (Albany NY). 2019;11:12641-12660 pubmed 出版商
He L, Fan X, Li Y, Chen M, Cui B, Chen G, et al. Overexpression of zinc finger protein 384 (ZNF 384), a poor prognostic predictor, promotes cell growth by upregulating the expression of Cyclin D1 in Hepatocellular carcinoma. Cell Death Dis. 2019;10:444 pubmed 出版商
You W, Hong Y, He H, Huang X, Tao W, Liang X, et al. TGF-β mediates aortic smooth muscle cell senescence in Marfan syndrome. Aging (Albany NY). 2019;11:3574-3584 pubmed 出版商
Fan Z, Li L, Li X, Zhang M, Dou M, Zhao J, et al. Anti-senescence role of heterozygous fumarate hydratase gene knockout in rat lung fibroblasts in vitro. Aging (Albany NY). 2019;11:573-589 pubmed 出版商
Ranoa D, Widau R, Mallon S, Parekh A, Nicolae C, Huang X, et al. STING Promotes Homeostasis via Regulation of Cell Proliferation and Chromosomal Stability. Cancer Res. 2019;79:1465-1479 pubmed 出版商
Zhang W, Liang Y, Li L, Wang X, Yan Z, Dong C, et al. The Nedd8-activating enzyme inhibitor MLN4924 (TAK-924/Pevonedistat) induces apoptosis via c-Myc-Noxa axis in head and neck squamous cell carcinoma. Cell Prolif. 2019;52:e12536 pubmed 出版商
Chu Y, Fang Y, Chi J, Li J, Zhang D, Zou Y, et al. Astragalus polysaccharides decrease proliferation, migration, and invasion but increase apoptosis of human osteosarcoma cells by up-regulation of microRNA-133a. Braz J Med Biol Res. 2018;51:e7665 pubmed 出版商
Dökümcü K, Simonian M, Farahani R. miR4673 improves fitness profile of neoplastic cells by induction of autophagy. Cell Death Dis. 2018;9:1068 pubmed 出版商
Huang D, Bi C, Zhao Q, Ding X, Bian C, Wang H, et al. Knockdown long non-coding RNA ANRIL inhibits proliferation, migration and invasion of HepG2 cells by down-regulation of miR-191. BMC Cancer. 2018;18:919 pubmed 出版商
Biernacki M, Łuczaj W, Jarocka Karpowicz I, Ambrożewicz E, Toczek M, Skrzydlewska E. The Effect of Long-Term Administration of Fatty Acid Amide Hydrolase Inhibitor URB597 on Oxidative Metabolism in the Heart of Rats with Primary and Secondary Hypertension. Molecules. 2018;23: pubmed 出版商
Zhou Y, Chu L, Wang Q, Dai W, Zhang X, Chen J, et al. CD59 is a potential biomarker of esophageal squamous cell carcinoma radioresistance by affecting DNA repair. Cell Death Dis. 2018;9:887 pubmed 出版商
Pathak G, Shah R, Kennedy B, Murphy J, Clements D, Konda P, et al. RTN4 Knockdown Dysregulates the AKT Pathway, Destabilizes the Cytoskeleton, and Enhances Paclitaxel-Induced Cytotoxicity in Cancers. Mol Ther. 2018;26:2019-2033 pubmed 出版商
Nayak G, Odaka Y, Prasad V, Solano A, Yeo E, Vemaraju S, et al. Developmental vascular regression is regulated by a Wnt/β-catenin, MYC and CDKN1A pathway that controls cell proliferation and cell death. Development. 2018;145: pubmed 出版商
Huang Y, Chen M, Guo Q, Chen Y, Zhang L, Chen Z, et al. Interleukin‑10 promotes primary rat hepatic stellate cell senescence by upregulating the expression levels of p53 and p21. Mol Med Rep. 2018;17:5700-5707 pubmed 出版商
Seth B, Yadav A, Agarwal S, Tiwari S, Chaturvedi R. Inhibition of the transforming growth factor-β/SMAD cascade mitigates the anti-neurogenic effects of the carbamate pesticide carbofuran. J Biol Chem. 2017;292:19423-19440 pubmed 出版商
Li X, Kang Y, Roife D, Lee Y, Pratt M, Perez M, et al. Prolonged exposure to extracellular lumican restrains pancreatic adenocarcinoma growth. Oncogene. 2017;36:5432-5438 pubmed 出版商
Ebata T, Mitsui Y, Sugimoto W, Maeda M, Araki K, Machiyama H, et al. Substrate Stiffness Influences Doxorubicin-Induced p53 Activation via ROCK2 Expression. Biomed Res Int. 2017;2017:5158961 pubmed 出版商
Piccinato C, Sertie A, Torres N, Ferretti M, Antonioli E. High OCT4 and Low p16(INK4A) Expressions Determine In Vitro Lifespan of Mesenchymal Stem Cells. Stem Cells Int. 2015;2015:369828 pubmed 出版商
产品信息
目录号 :
ab109199
ItemName :
抗p21抗体[EPR3993]
类别 :
抗体
宿主 :
克隆性 :
单克隆
共轭标签 :
未共轭
克隆名称 :
EPR3993
规格 :
10微升, 100微升
物种摘要 :
AGMk, Hu, Ms, Rat
应用摘要 :
免疫细胞化学/IF, 免疫印迹
公司信息
艾博抗(上海)贸易有限公司
上海市浦东新区伽利略路338号5幢4层5401室
cn.technical@abcam.com
http://www.abcam.cn
400-628-6880 86-21-5110 5938
公司总部: 英国
Abcam是全球知名的生命科学研究领域产品提供商,产品涵盖一抗、二抗、蛋白、多肽及ELISA kit。