产品简要
公司名称 :
艾博抗(上海)贸易有限公司
其他品牌 :
Epitomics, Ascent Scientific, MitoSciences
产品类型 :
抗体
产品名称 :
抗p21抗体[EPR362]
目录 :
ab109520
规格 :
10微升, 100微升
克隆性 :
单克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
克隆名称 :
EPR362
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀, 流式细胞仪, 免疫组化-石蜡切片, 免疫印迹基因敲除验证
文章摘录数: 43
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 人类; 1:500; 图 4b
Lo Cascio C, McNamara J, Melendez E, Lewis E, Dufault M, Sanai N, et al. Nonredundant, isoform-specific roles of HDAC1 in glioma stem cells. JCI Insight. 2021;6: pubmed 出版商
  • 免疫组化; 大鼠; 1:100; 图 1b
Li T, Yang X, Xu D, Gao Z, Gao Y, Jin F, et al. OC-STAMP Overexpression Drives Lung Alveolar Epithelial Cell Type II Senescence in Silicosis. Oxid Med Cell Longev. 2021;2021:4158495 pubmed 出版商
  • 免疫印迹; 人类; 图 s4s
Fan Z, Turiel G, Ardicoglu R, Ghobrial M, Masschelein E, Kocijan T, et al. Exercise-induced angiogenesis is dependent on metabolically primed ATF3/4+ endothelial cells. Cell Metab. 2021;: pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 7a
Shi L, Magee P, Fassan M, Sahoo S, Leong H, LEE D, et al. A KRAS-responsive long non-coding RNA controls microRNA processing. Nat Commun. 2021;12:2038 pubmed 出版商
  • 免疫印迹; 小鼠; 图 3i
  • 免疫印迹; 人类; 1:1000; 图 3h
Nishad R, Mukhi D, Singh A, Motrapu M, Chintala K, Tammineni P, et al. Growth hormone induces mitotic catastrophe of glomerular podocytes and contributes to proteinuria. Cell Death Dis. 2021;12:342 pubmed 出版商
  • 免疫印迹; 人类; 图 6d
Zhao Z, Wang Y, Yun D, Huang Q, Meng D, Li Q, et al. TRIM21 overexpression promotes tumor progression by regulating cell proliferation, cell migration and cell senescence in human glioma. Am J Cancer Res. 2020;10:114-130 pubmed
  • 免疫印迹; 人类; 图 2d
Wang L, Wang J, Jin T, Zhou Y, Chen Q. FoxG1 facilitates proliferation and inhibits differentiation by downregulating FoxO/Smad signaling in glioblastoma. Biochem Biophys Res Commun. 2018;504:46-53 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 5a
Zhu X, Wang K, Zhang K, Zhang T, Yin Y, Xu F. Ziyuglycoside I Inhibits the Proliferation of MDA-MB-231 Breast Carcinoma Cells through Inducing p53-Mediated G2/M Cell Cycle Arrest and Intrinsic/Extrinsic Apoptosis. Int J Mol Sci. 2016;17: pubmed
  • 免疫印迹基因敲除验证; 人类; 1:2000; 图 4
  • 免疫细胞化学; 人类; 1:200; 图 4
Wang J, Hu K, Guo J, Cheng F, Lv J, Jiang W, et al. Suppression of KRas-mutant cancer through the combined inhibition of KRAS with PLK1 and ROCK. Nat Commun. 2016;7:11363 pubmed 出版商
  • 免疫印迹; 人类; 1:500; 图 5
Chen R, Liu H, Cheng Q, Jiang B, Peng R, Zou Q, et al. MicroRNA-93 promotes the malignant phenotypes of human glioma cells and induces their chemoresistance to temozolomide. Biol Open. 2016;5:669-77 pubmed 出版商
  • 免疫印迹; 人类; 图 5d
Zhu N, Wang H, Wang B, Wei J, Shan W, Feng J, et al. A Member of the Nuclear Receptor Superfamily, Designated as NR2F2, Supports the Self-Renewal Capacity and Pluripotency of Human Bone Marrow-Derived Mesenchymal Stem Cells. Stem Cells Int. 2016;2016:5687589 pubmed 出版商
  • 免疫印迹; 人类; 图 2
Dong L, Yu D, Wu N, Wang H, Niu J, Wang Y, et al. Echinacoside Induces Apoptosis in Human SW480 Colorectal Cancer Cells by Induction of Oxidative DNA Damages. Int J Mol Sci. 2015;16:14655-68 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 5
Shi Z, Shi F, Wang Y, Sheftel A, Nie G, Zhao Y, et al. Mitochondrial ferritin, a new target for inhibiting neuronal tumor cell proliferation. Cell Mol Life Sci. 2015;72:983-97 pubmed 出版商
Wang C, Rabadan Ros R, Martínez Redondo P, Ma Z, Shi L, Xue Y, et al. In vivo partial reprogramming of myofibers promotes muscle regeneration by remodeling the stem cell niche. Nat Commun. 2021;12:3094 pubmed 出版商
Obaya A, Mohammed A, Rashied H, Morsy A, Osman G, Allam A, et al. Evaluating the value of Amphiregulin, Phosphatase and Tensin Homologue (PTEN) and P21 Expression for Anti-EGFR Treatment in Metastatic Colorectal Carcinoma. Asian Pac J Cancer Prev. 2021;22:1025-1034 pubmed 出版商
Hu B, Yang X, Yang X, Sang X. LncRNA CYTOR affects the proliferation, cell cycle and apoptosis of hepatocellular carcinoma cells by regulating the miR-125b-5p/KIAA1522 axis. Aging (Albany NY). 2020;13:2626-2639 pubmed 出版商
Pu Q, Lv Y, Dong K, Geng W, Gao H. Tumor suppressor OTUD3 induces growth inhibition and apoptosis by directly deubiquitinating and stabilizing p53 in invasive breast carcinoma cells. BMC Cancer. 2020;20:583 pubmed 出版商
Sharma S, Munger K. KDM6A-Mediated Expression of the Long Noncoding RNA DINO Causes TP53 Tumor Suppressor Stabilization in Human Papillomavirus 16 E7-Expressing Cells. J Virol. 2020;94: pubmed 出版商
Rizzotto D, Zaccara S, Rossi A, Galbraith M, Andrysik Z, Pandey A, et al. Nutlin-Induced Apoptosis Is Specified by a Translation Program Regulated by PCBP2 and DHX30. Cell Rep. 2020;30:4355-4369.e6 pubmed 出版商
Yu A, Wang Z, Wu W, Chen K, Yan S, Mao Z. Circular RNA CircCCNB1 sponges micro RNA-449a to inhibit cellular senescence by targeting CCNE2. Aging (Albany NY). 2019;11:10220-10241 pubmed 出版商
Guo W, Gao R, Zhang W, Ge W, Ren M, Li B, et al. IgE Aggravates the Senescence of Smooth Muscle Cells in Abdominal Aortic Aneurysm by Upregulating LincRNA-p21. Aging Dis. 2019;10:699-710 pubmed 出版商
Borghesan M, Fafián Labora J, Eleftheriadou O, Carpintero Fernández P, Pàez Ribes M, Vizcay Barrena G, et al. Small Extracellular Vesicles Are Key Regulators of Non-cell Autonomous Intercellular Communication in Senescence via the Interferon Protein IFITM3. Cell Rep. 2019;27:3956-3971.e6 pubmed 出版商
Kido T, Li Y, Tanaka Y, Dahiya R, Chris Lau Y. The X-linked tumor suppressor TSPX downregulates cancer-drivers/oncogenes in prostate cancer in a C-terminal acidic domain dependent manner. Oncotarget. 2019;10:1491-1506 pubmed 出版商
Wang D, Dai J, Hou S, Qian Y. LncRNA SNHG20 predicts a poor prognosis and promotes cell progression in epithelial ovarian cancer. Biosci Rep. 2019;39: pubmed 出版商
Liu Y, Hu X, Shan X, Chen K, Tang H. Rosiglitazone metformin adduct inhibits hepatocellular carcinoma proliferation via activation of AMPK/p21 pathway. Cancer Cell Int. 2019;19:13 pubmed 出版商
Nordén E, Heiss E. Urolithin A gains in antiproliferative capacity by reducing the glycolytic potential via the p53/TIGAR axis in colon cancer cells. Carcinogenesis. 2019;40:93-101 pubmed 出版商
Li Z, Liu T, Ma J, Guo Q, Ma L, Lv Q, et al. TGF-β induces corneal endothelial senescence via increase of mitochondrial reactive oxygen species in chronic corneal allograft failure. Aging (Albany NY). 2018;10:3474-3485 pubmed 出版商
Majerská J, Feretzaki M, Glousker G, Lingner J. Transformation-induced stress at telomeres is counteracted through changes in the telomeric proteome including SAMHD1. Life Sci Alliance. 2018;1:e201800121 pubmed 出版商
Zeng F, Huang L, Cheng X, Yang X, Li T, Feng G, et al. Overexpression of LASS2 inhibits proliferation and causes G0/G1 cell cycle arrest in papillary thyroid cancer. Cancer Cell Int. 2018;18:151 pubmed 出版商
Chen C, Zhao Z, Tang S, Zhang C. Rab-like protein 1 A is upregulated by cisplatin treatment and partially inhibits chemoresistance by regulating p53 activity. Oncol Lett. 2018;16:4593-4599 pubmed 出版商
Tian M, Yang S, Yan X. Icariin reduces human colon carcinoma cell growth and metastasis by enhancing p53 activities. Braz J Med Biol Res. 2018;51:e7151 pubmed 出版商
Kawano K, Doucet A, Ueno M, Kariya R, An W, Marzetta F, et al. HIV-1 Vpr and p21 restrict LINE-1 mobility. Nucleic Acids Res. 2018;46:8454-8470 pubmed 出版商
Shao G, Wan X, Lai W, Wu C, Jin J, Liu X, et al. Inhibition of lysine-specific demethylase 1 prevents proliferation and mediates cisplatin sensitivity in ovarian cancer cells. Oncol Lett. 2018;15:9025-9032 pubmed 出版商
Ding L, Zhang S, Xu M, Zhang R, Sui P, Yang Q. MicroRNA-27a contributes to the malignant behavior of gastric cancer cells by directly targeting PH domain and leucine-rich repeat protein phosphatase 2. J Exp Clin Cancer Res. 2017;36:45 pubmed 出版商
Fan Y, Li H, Liang X, Xiang Z. CBX3 promotes colon cancer cell proliferation by CDK6 kinase-independent function during cell cycle. Oncotarget. 2017;8:19934-19946 pubmed 出版商
Li Z, Chen Z, Zhang T, Wei C, Shi W. TGF-? and NF-?B signaling pathway crosstalk potentiates corneal epithelial senescence through an RNA stress response. Aging (Albany NY). 2016;8:2337-2354 pubmed 出版商
Chung I, Liu H, Lin Y, Chi H, Huang Y, Yang C, et al. ChIP-on-chip analysis of thyroid hormone-regulated genes and their physiological significance. Oncotarget. 2016;7:22448-59 pubmed 出版商
Carter R, Westhorpe A, Romero M, Habtemariam A, Gallevo C, Bark Y, et al. Radiosensitisation of human colorectal cancer cells by ruthenium(II) arene anticancer complexes. Sci Rep. 2016;6:20596 pubmed 出版商
Wu J, Chen Z, Liu Q, Zeng W, Wu X, Lin B. Silencing of Kv1.5 Gene Inhibits Proliferation and Induces Apoptosis of Osteosarcoma Cells. Int J Mol Sci. 2015;16:26914-26 pubmed 出版商
Wang X, Gong Y, Jin B, Wu C, Yang J, Wang L, et al. Long non-coding RNA urothelial carcinoma associated 1 induces cell replication by inhibiting BRG1 in 5637 cells. Oncol Rep. 2014;32:1281-90 pubmed 出版商
Wang J, Feng J, Han J, Zhang B, Mao W. The molecular mechanisms of Tanshinone IIA on the apoptosis and arrest of human esophageal carcinoma cells. Biomed Res Int. 2014;2014:582730 pubmed 出版商
Frederick P, Green H, Huang J, Egger M, Frieboes H, Grizzle W, et al. Chemoresistance in ovarian cancer linked to expression of microRNAs. Biotech Histochem. 2013;88:403-9 pubmed 出版商
Yang M, Yuan F, Li P, Chen Z, Chen A, Li S, et al. Interferon regulatory factor 4 binding protein is a novel p53 target gene and suppresses cisplatin-induced apoptosis of breast cancer cells. Mol Cancer. 2012;11:54 pubmed
产品信息
目录号 :
ab109520
ItemName :
抗p21抗体[EPR362]
类别 :
抗体
宿主 :
克隆性 :
单克隆
共轭标签 :
未共轭
克隆名称 :
EPR362
规格 :
10微升, 100微升
物种摘要 :
Hu
应用摘要 :
Flow Cyt, ICC/IF, IHC-P, IP, WB
公司信息
艾博抗(上海)贸易有限公司
上海市浦东新区伽利略路338号5幢4层5401室
cn.technical@abcam.com
http://www.abcam.cn
400-628-6880 86-21-5110 5938
公司总部: 英国
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