产品简要
公司名称 :
艾博抗(上海)贸易有限公司
其他品牌 :
Epitomics, Ascent Scientific, MitoSciences
产品类型 :
抗体
产品名称 :
抗p53抗体[DO-1]-ChIP级
目录 :
ab1101
规格 :
10微克
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
DO-1
反应物种 :
人类, 小鼠
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学, 免疫沉淀, 流式细胞仪, 染色质免疫沉淀 , 免疫组化-石蜡切片, 免疫组化-冰冻切片, ChIP-Seq, 免疫印迹基因敲除验证
文章摘录数: 36
出版应用/物种/样本/稀释参考文献
  • ChIP-Seq; 人类; 图 2a, s6c
Boettcher S, Miller P, Sharma R, McConkey M, Leventhal M, Krivtsov A, et al. A dominant-negative effect drives selection of TP53 missense mutations in myeloid malignancies. Science. 2019;365:599-604 pubmed 出版商
  • 免疫印迹; 人类; 图 2d
Fu L, Hu Y, Song M, Liu Z, Zhang W, Yu F, et al. Up-regulation of FOXD1 by YAP alleviates senescence and osteoarthritis. PLoS Biol. 2019;17:e3000201 pubmed 出版商
  • 免疫印迹; 人类; 图 7a
Yang Y, Peng X. The silencing of long non-coding RNA ANRIL suppresses invasion, and promotes apoptosis of retinoblastoma cells through the ATM-E2F1 signaling pathway. Biosci Rep. 2018;38: pubmed 出版商
  • 免疫印迹; 人类; 图 7a
Zhang W, Kang M, Zhang T, Li B, Liao X, Wang R. Triptolide Combined with Radiotherapy for the Treatment of Nasopharyngeal Carcinoma via NF-κB-Related Mechanism. Int J Mol Sci. 2016;17: pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 s6
Yu Z, Mouillesseaux K, Kushner E, Bautch V. Tumor-Derived Factors and Reduced p53 Promote Endothelial Cell Centrosome Over-Duplication. PLoS ONE. 2016;11:e0168334 pubmed 出版商
  • 免疫沉淀; 人类; 图 4c
  • 免疫印迹; 人类; 图 4c
Tu S, Lin Y, Huang C, Yang P, Chang H, Chang C, et al. Protein phosphatase Mg2+/Mn2+ dependent 1F promotes smoking-induced breast cancer by inactivating phosphorylated-p53-induced signals. Oncotarget. 2016;7:77516-77531 pubmed 出版商
  • 免疫印迹基因敲除验证; 人类; 图 s1
Hong X, Liu W, Song R, Shah J, Feng X, Tsang C, et al. SOX9 is targeted for proteasomal degradation by the E3 ligase FBW7 in response to DNA damage. Nucleic Acids Res. 2016;44:8855-8869 pubmed
  • 免疫细胞化学; 人类; 图 2a
Garcia C, Videla Richardson G, Dimopoulos N, Fernandez Espinosa D, Miriuka S, Sevlever G, et al. Human Pluripotent Stem Cells and Derived Neuroprogenitors Display Differential Degrees of Susceptibility to BH3 Mimetics ABT-263, WEHI-539 and ABT-199. PLoS ONE. 2016;11:e0152607 pubmed 出版商
  • 免疫印迹; 人类; 图 2
Polettini J, Behnia F, Taylor B, Saade G, Taylor R, Menon R. Telomere Fragment Induced Amnion Cell Senescence: A Contributor to Parturition?. PLoS ONE. 2015;10:e0137188 pubmed 出版商
  • 免疫印迹; 人类
Li M, Pehar M, Liu Y, Bhattacharyya A, Zhang S, O Riordan K, et al. The amyloid precursor protein (APP) intracellular domain regulates translation of p44, a short isoform of p53, through an IRES-dependent mechanism. Neurobiol Aging. 2015;36:2725-36 pubmed 出版商
  • 免疫组化; 人类; 1:500; 图 1
Zhang P, Wu S, Wang Y, Fan Z, Li C, Feng M, et al. p53, MDM2, eIF4E and EGFR expression in nasopharyngeal carcinoma and their correlation with clinicopathological characteristics and prognosis: A retrospective study. Oncol Lett. 2015;9:113-118 pubmed
  • 免疫印迹; 人类
Micklem D, Blø M, Bergström P, Hodneland E, Tiron C, Høiby T, et al. Flow cytometry-based functional selection of RNA interference triggers for efficient epi-allelic analysis of therapeutic targets. BMC Biotechnol. 2014;14:57 pubmed 出版商
Lou J, Hao Y, Lin K, Lyu Y, Chen M, Wang H, et al. Circular RNA CDR1as disrupts the p53/MDM2 complex to inhibit Gliomagenesis. Mol Cancer. 2020;19:138 pubmed 出版商
Videla Richardson G, Furmento V, Garcia C, Morris Hanon O, Sevlever G, Romorini L, et al. Human embryonic stem cells display a pronounced sensitivity to the cyclin dependent kinase inhibitor Roscovitine. BMC Mol Cell Biol. 2019;20:40 pubmed 出版商
Guo W, Gao R, Zhang W, Ge W, Ren M, Li B, et al. IgE Aggravates the Senescence of Smooth Muscle Cells in Abdominal Aortic Aneurysm by Upregulating LincRNA-p21. Aging Dis. 2019;10:699-710 pubmed 出版商
Shao L, Zuo X, Yang Y, Zhang Y, Yang N, Shen B, et al. The inherited variations of a p53-responsive enhancer in 13q12.12 confer lung cancer risk by attenuating TNFRSF19 expression. Genome Biol. 2019;20:103 pubmed 出版商
Bulatov E, Sayarova R, Mingaleeva R, Miftakhova R, Gomzikova M, Ignatyev Y, et al. Isatin-Schiff base-copper (II) complex induces cell death in p53-positive tumors. Cell Death Discov. 2018;4:103 pubmed 出版商
Chen C, Zhao Z, Tang S, Zhang C. Rab-like protein 1 A is upregulated by cisplatin treatment and partially inhibits chemoresistance by regulating p53 activity. Oncol Lett. 2018;16:4593-4599 pubmed 出版商
Waldherr M, Mišík M, Ferk F, Tomc J, Zegura B, Filipic M, et al. Use of HuH6 and other human-derived hepatoma lines for the detection of genotoxins: a new hope for laboratory animals?. Arch Toxicol. 2018;92:921-934 pubmed 出版商
Liao P, Zeng S, Zhou X, Chen T, Zhou F, Cao B, et al. Mutant p53 Gains Its Function via c-Myc Activation upon CDK4 Phosphorylation at Serine 249 and Consequent PIN1 Binding. Mol Cell. 2017;68:1134-1146.e6 pubmed 出版商
Han S, Meng L, Jiang Y, Cheng W, Tie X, Xia J, et al. Lithium enhances the antitumour effect of temozolomide against TP53 wild-type glioblastoma cells via NFAT1/FasL signalling. Br J Cancer. 2017;116:1302-1311 pubmed 出版商
Liu T, Xiong J, Yi S, Zhang H, Zhou S, Gu L, et al. FKBP12 enhances sensitivity to chemotherapy-induced cancer cell apoptosis by inhibiting MDM2. Oncogene. 2017;36:1678-1686 pubmed 出版商
Yang K, Yan J, Peng L, Zou Y, He F, Gan H, et al. Effect of PLC? gene silencing on inhibiting the cancerous transformation of ulcerative colitis. Exp Ther Med. 2016;12:422-426 pubmed
Song Y, Hu B, Qu H, Wang L, Zhang Y, Tao J, et al. Novel 1, 3-N, O-Spiroheterocyclic compounds inhibit heparanase activity and enhance nedaplatin-induced cytotoxicity in cervical cancer cells. Oncotarget. 2016;7:36154-36167 pubmed 出版商
Nguyen H, Allali Hassani A, Antonysamy S, Chang S, Chen L, Curtis C, et al. LLY-507, a Cell-active, Potent, and Selective Inhibitor of Protein-lysine Methyltransferase SMYD2. J Biol Chem. 2015;290:13641-53 pubmed 出版商
Menon R, Boldogh I, Hawkins H, Woodson M, Polettini J, Syed T, et al. Histological evidence of oxidative stress and premature senescence in preterm premature rupture of the human fetal membranes recapitulated in vitro. Am J Pathol. 2014;184:1740-51 pubmed 出版商
Garcia C, Videla Richardson G, Romorini L, Miriuka S, Sevlever G, Scassa M. Topoisomerase I inhibitor, camptothecin, induces apoptogenic signaling in human embryonic stem cells. Stem Cell Res. 2014;12:400-14 pubmed 出版商
Pezdirc M, Zegura B, Filipic M. Genotoxicity and induction of DNA damage responsive genes by food-borne heterocyclic aromatic amines in human hepatoma HepG2 cells. Food Chem Toxicol. 2013;59:386-94 pubmed 出版商
Thompson C, Fedorov Y, Brown D, Suh M, Proctor D, Kuriakose L, et al. Assessment of Cr(VI)-induced cytotoxicity and genotoxicity using high content analysis. PLoS ONE. 2012;7:e42720 pubmed 出版商
Hanks T, Gauss K. Pleomorphic adenoma gene-like 2 regulates expression of the p53 family member, p73, and induces cell cycle block and apoptosis in human promonocytic U937 cells. Apoptosis. 2012;17:236-47 pubmed 出版商
Vanderplanck C, Ansseau E, Charron S, Stricwant N, Tassin A, Laoudj Chenivesse D, et al. The FSHD atrophic myotube phenotype is caused by DUX4 expression. PLoS ONE. 2011;6:e26820 pubmed 出版商
Nieva J, Song B, Rogel J, Kujawara D, Altobel L, Izharrudin A, et al. Cholesterol secosterol aldehydes induce amyloidogenesis and dysfunction of wild-type tumor protein p53. Chem Biol. 2011;18:920-7 pubmed 出版商
Kenig S, Frangez R, Pucer A, Lah T. Inhibition of cathepsin L lowers the apoptotic threshold of glioblastoma cells by up-regulating p53 and transcription of caspases 3 and 7. Apoptosis. 2011;16:671-82 pubmed 出版商
Slack J, Jones L, Bhatia M, Thompson P. Autodeimination of protein arginine deiminase 4 alters protein-protein interactions but not activity. Biochemistry. 2011;50:3997-4010 pubmed 出版商
Ghavami S, Mutawe M, Hauff K, Stelmack G, Schaafsma D, Sharma P, et al. Statin-triggered cell death in primary human lung mesenchymal cells involves p53-PUMA and release of Smac and Omi but not cytochrome c. Biochim Biophys Acta. 2010;1803:452-67 pubmed 出版商
Ottewell P, Woodward J, Lefley D, Evans C, Coleman R, Holen I. Anticancer mechanisms of doxorubicin and zoledronic acid in breast cancer tumor growth in bone. Mol Cancer Ther. 2009;8:2821-32 pubmed 出版商
产品信息
目录号 :
ab1101
ItemName :
抗p53抗体[DO-1]-ChIP级
产品类型 :
一抗
宿主物种 :
小鼠
克隆性 :
单克隆
共轭标签 :
Not Conjugated
抗原修饰 :
No Modifications
克隆名称 :
DO-1
规格 :
10微克
物种摘要 :
Hu
用途 :
ChIP, ELISA, Flow Cyt, ICC/IF, IHC-Fr, IHC-P, IP, WB
规格说明 :
Other sizes available: 50 µg,100 µg,100 µl
公司信息
艾博抗(上海)贸易有限公司
上海市浦东新区伽利略路338号5幢4层5401室
cn.technical@abcam.com
http://www.abcam.cn
400-628-6880 86-21-5110 5938
公司总部: 英国
Abcam是全球知名的生命科学研究领域产品提供商,产品涵盖一抗、二抗、蛋白、多肽及ELISA kit。