产品简要
公司名称 :
艾博抗(上海)贸易有限公司
其他品牌 :
Epitomics, Ascent Scientific, MitoSciences
产品类型 :
抗体
产品名称 :
抗组蛋白H2A.X抗体-ChIP级
目录 :
ab11175
规格 :
50微克
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀, 染色质免疫沉淀 , 免疫组化-石蜡切片, 免疫组化-冰冻切片, reverse phase protein lysate microarray
文章摘录数: 27
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 人类; 图 4c
Zhu B, Ren C, Du K, Zhu H, Ai Y, Kang F, et al. Olean-28,13b-olide 2 plays a role in cisplatin-mediated apoptosis and reverses cisplatin resistance in human lung cancer through multiple signaling pathways. Biochem Pharmacol. 2019;170:113642 pubmed 出版商
  • 免疫印迹; 人类
Gao R, Chakraborty A, Geater C, Pradhan S, Gordon K, Snowden J, et al. Mutant huntingtin impairs PNKP and ATXN3, disrupting DNA repair and transcription. elife. 2019;8: pubmed 出版商
  • 免疫细胞化学; 人类; 图 s1c
Kostyushev D, Kostyusheva A, Brezgin S, Zarifyan D, Utkina A, Goptar I, et al. Suppressing the NHEJ pathway by DNA-PKcs inhibitor NU7026 prevents degradation of HBV cccDNA cleaved by CRISPR/Cas9. Sci Rep. 2019;9:1847 pubmed 出版商
  • 免疫印迹; 人类; 图 3b
Paul A, Wang B. RNF8- and Ube2S-Dependent Ubiquitin Lysine 11-Linkage Modification in Response to DNA Damage. Mol Cell. 2017;66:458-472.e5 pubmed 出版商
  • 免疫细胞化学; 小鼠; 图 1b
  • 免疫印迹; 小鼠; 图 1c
Ohno S, Ikeda J, Naito Y, Okuzaki D, Sasakura T, Fukushima K, et al. Comprehensive phenotypic analysis of knockout mice deficient in cyclin G1 and cyclin G2. Sci Rep. 2016;6:39091 pubmed 出版商
  • 免疫印迹; 人类; 1:2000; 图 6
Li L, Shi L, Yang S, Yan R, Zhang D, Yang J, et al. SIRT7 is a histone desuccinylase that functionally links to chromatin compaction and genome stability. Nat Commun. 2016;7:12235 pubmed 出版商
  • 免疫印迹; 小鼠; 1:5000; 图 5b
Adriaens C, Standaert L, Barra J, Latil M, Verfaillie A, Kalev P, et al. p53 induces formation of NEAT1 lncRNA-containing paraspeckles that modulate replication stress response and chemosensitivity. Nat Med. 2016;22:861-8 pubmed 出版商
  • 免疫印迹; 小鼠; 1:5000; 图 2
Baleriola J, Álvarez Lindo N, de la Villa P, Bernad A, Blanco L, Suárez T, et al. Increased neuronal death and disturbed axonal growth in the Polμ-deficient mouse embryonic retina. Sci Rep. 2016;6:25928 pubmed 出版商
  • 免疫细胞化学; 人类; 图 3
  • 免疫印迹; 人类; 图 7
Chiang T, le Sage C, Larrieu D, Demir M, Jackson S. CRISPR-Cas9(D10A) nickase-based genotypic and phenotypic screening to enhance genome editing. Sci Rep. 2016;6:24356 pubmed 出版商
  • reverse phase protein lysate microarray; 小鼠; 图 s1.b,c
  • 免疫印迹; 小鼠; 图 1a
  • 免疫组化; 人类; 1:100; 图 4b
Gruosso T, Mieulet V, Cardon M, Bourachot B, Kieffer Y, Devun F, et al. Chronic oxidative stress promotes H2AX protein degradation and enhances chemosensitivity in breast cancer patients. EMBO Mol Med. 2016;8:527-49 pubmed 出版商
  • 免疫细胞化学; 人类; 图 s1
Jacobs K, Zambelli F, Mertzanidou A, Smolders I, Geens M, Nguyen H, et al. Higher-Density Culture in Human Embryonic Stem Cells Results in DNA Damage and Genome Instability. Stem Cell Reports. 2016;6:330-41 pubmed 出版商
  • 免疫印迹; 人类; 图 s3
Nagy Z, Kalousi A, Furst A, Koch M, Fischer B, Soutoglou E. Tankyrases Promote Homologous Recombination and Check Point Activation in Response to DSBs. PLoS Genet. 2016;12:e1005791 pubmed 出版商
  • 免疫细胞化学; 人类; 图 s2
  • 免疫印迹; 人类; 1:1000; 图 s2
Pan H, Guan D, Liu X, Li J, Wang L, Wu J, et al. SIRT6 safeguards human mesenchymal stem cells from oxidative stress by coactivating NRF2. Cell Res. 2016;26:190-205 pubmed 出版商
  • 免疫印迹; 人类; 图 7
Cristini A, Park J, Capranico G, Legube G, Favre G, Sordet O. DNA-PK triggers histone ubiquitination and signaling in response to DNA double-strand breaks produced during the repair of transcription-blocking topoisomerase I lesions. Nucleic Acids Res. 2016;44:1161-78 pubmed 出版商
  • 免疫印迹; 大鼠; 图 3
  • 免疫印迹; 小鼠; 图 6
Sabirzhanov B, Stoica B, Zhao Z, Loane D, Wu J, Dorsey S, et al. miR-711 upregulation induces neuronal cell death after traumatic brain injury. Cell Death Differ. 2016;23:654-68 pubmed 出版商
Zhai B, Li Y, Kotapalli S, Bacha J, Brown D, Steinø A, et al. Dianhydrogalactitol synergizes with topoisomerase poisons to overcome DNA repair activity in tumor cells. Cell Death Dis. 2020;11:577 pubmed 出版商
Wei F, Wang A, Wang Q, Han W, Rong R, Wang L, et al. Plasma endothelial cells-derived extracellular vesicles promote wound healing in diabetes through YAP and the PI3K/Akt/mTOR pathway. Aging (Albany NY). 2020;12:12002-12018 pubmed 出版商
Di Tano M, Raucci F, Vernieri C, Caffa I, Buono R, Fanti M, et al. Synergistic effect of fasting-mimicking diet and vitamin C against KRAS mutated cancers. Nat Commun. 2020;11:2332 pubmed 出版商
Munnur D, Somers J, Skalka G, Weston R, Jukes Jones R, Bhogadia M, et al. NR4A Nuclear Receptors Target Poly-ADP-Ribosylated DNA-PKcs Protein to Promote DNA Repair. Cell Rep. 2019;26:2028-2036.e6 pubmed 出版商
Piquet S, Le Parc F, Bai S, Chevallier O, Adam S, Polo S. The Histone Chaperone FACT Coordinates H2A.X-Dependent Signaling and Repair of DNA Damage. Mol Cell. 2018;72:888-901.e7 pubmed 出版商
Leung J, Emery L, Miller K. CRISPR/Cas9 Gene Editing of Human Histone H2A Variant H2AX and MacroH2A. Methods Mol Biol. 2018;1832:255-269 pubmed 出版商
Balmus G, Larrieu D, Barros A, Collins C, Abrudan M, Demir M, et al. Targeting of NAT10 enhances healthspan in a mouse model of human accelerated aging syndrome. Nat Commun. 2018;9:1700 pubmed 出版商
Zhou J, Li J, Serafim R, Ketchum S, Ferreira C, Liu J, et al. Human CHD1 is required for early DNA-damage signaling and is uniquely regulated by its N terminus. Nucleic Acids Res. 2018;46:3891-3905 pubmed 出版商
Hodroj D, Recolin B, Serhal K, Martinez S, Tsanov N, Abou Merhi R, et al. An ATR-dependent function for the Ddx19 RNA helicase in nuclear R-loop metabolism. EMBO J. 2017;36:1182-1198 pubmed 出版商
Xiong H, Nie X, Zou Y, Gong C, Li Y, Wu H, et al. Twist1 Enhances Hypoxia Induced Radioresistance in Cervical Cancer Cells by Promoting Nuclear EGFR Localization. J Cancer. 2017;8:345-353 pubmed 出版商
Li X, Eberhardt A, Hansen J, Bohmann D, Li H, Schor N. Methylation of the phosphatase-transcription activator EYA1 by protein arginine methyltransferase 1: mechanistic, functional, and structural studies. FASEB J. 2017;31:2327-2339 pubmed 出版商
Xu C, Zhang L, Duan L, Lu C. MicroRNA-3196 is inhibited by H2AX phosphorylation and attenuates lung cancer cell apoptosis by downregulating PUMA. Oncotarget. 2016;7:77764-77776 pubmed 出版商
产品信息
目录号 :
ab11175
ItemName :
抗组蛋白H2A.X抗体-ChIP级
产品类型 :
一抗
宿主物种 :
克隆性 :
多克隆
共轭标签 :
Not Conjugated
抗原修饰 :
No Modifications
规格 :
50微克
物种摘要 :
Hu, Mk, Ms, Rat
用途 :
ChIP, ICC/IF, IHC-Fr, IHC-P, IP, WB
公司信息
艾博抗(上海)贸易有限公司
上海市浦东新区伽利略路338号5幢4层5401室
cn.technical@abcam.com
http://www.abcam.cn
400-628-6880 86-21-5110 5938
公司总部: 英国
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