产品简要
公司名称 :
艾博抗(上海)贸易有限公司
其他品牌 :
Epitomics, Ascent Scientific, MitoSciences
产品类型 :
抗体
产品名称 :
抗γ-微管抗体[GTU-88]
目录 :
ab11316
规格 :
100微升
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
GTU-88
反应物种 :
人类, 小鼠, 大鼠,
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学, 免疫组化-石蜡切片, 免疫组化-冰冻切片
文章摘录数: 84
出版应用/物种/样本/稀释参考文献
  • 免疫细胞化学; 人类; 1:500; 图 5a
Schilpp C, Lochbaum R, Braubach P, Jonigk D, Frick M, Dietl P, et al. TGF-β1 increases permeability of ciliated airway epithelia via redistribution of claudin 3 from tight junction into cell nuclei. Pflugers Arch. 2021;473:287-311 pubmed 出版商
  • 免疫细胞化学; 人类; 图 3b
Peta C, Tsirimonaki E, Samouil D, Georgiadou K, Mangoura D. Nuclear Isoforms of Neurofibromin Are Required for Proper Spindle Organization and Chromosome Segregation. Cells. 2020;9: pubmed 出版商
  • 免疫细胞化学; 人类; 1:500; 图 1b
Magupalli V, Negro R, Tian Y, Hauenstein A, Di Caprio G, Skillern W, et al. HDAC6 mediates an aggresome-like mechanism for NLRP3 and pyrin inflammasome activation. Science. 2020;369: pubmed 出版商
  • 免疫细胞化学; 人类; 图 s3f
  • 免疫印迹; 人类; 1:1000; 图 5b
Song K, Gras C, Capin G, Gimber N, Lehmann M, Mohd S, et al. A SEPT1-based scaffold is required for Golgi integrity and function. J Cell Sci. 2019;132: pubmed 出版商
  • 免疫细胞化学; 人类; 1:400; 图 3c
  • 免疫印迹; 人类; 1:1000; 图 4a
Full F, van Gent M, Sparrer K, Chiang C, Zurenski M, Scherer M, et al. Centrosomal protein TRIM43 restricts herpesvirus infection by regulating nuclear lamina integrity. Nat Microbiol. 2019;4:164-176 pubmed 出版商
  • 免疫细胞化学; 人类; 1:200; 图 2d
  • 免疫印迹; 人类; 1:1000; 图 5d
Morris E, Kawamura E, Gillespie J, Balgi A, Kannan N, Muller W, et al. Stat3 regulates centrosome clustering in cancer cells via Stathmin/PLK1. Nat Commun. 2017;8:15289 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 s5
Feringa F, Krenning L, Koch A, van den Berg J, van den Broek B, Jalink K, et al. Hypersensitivity to DNA damage in antephase as a safeguard for genome stability. Nat Commun. 2016;7:12618 pubmed 出版商
  • 免疫印迹; 小鼠; 图 2
Myers S, Peddada S, Chatterjee N, Friedrich T, Tomoda K, Krings G, et al. SOX2 O-GlcNAcylation alters its protein-protein interactions and genomic occupancy to modulate gene expression in pluripotent cells. elife. 2016;5:e10647 pubmed 出版商
  • 免疫细胞化学; 人类; 图 s9
Munkley J, Oltean S, Vodák D, Wilson B, Livermore K, Zhou Y, et al. The androgen receptor controls expression of the cancer-associated sTn antigen and cell adhesion through induction of ST6GalNAc1 in prostate cancer. Oncotarget. 2015;6:34358-74 pubmed 出版商
  • 免疫细胞化学; 人类; 1:250; 图 3f
Meissner C, Lorenz H, Hehn B, Lemberg M. Intramembrane protease PARL defines a negative regulator of PINK1- and PARK2/Parkin-dependent mitophagy. Autophagy. 2015;11:1484-98 pubmed 出版商
  • 免疫细胞化学; 人类; 1:250; 图 3f
Moyer T, Clutario K, Lambrus B, Daggubati V, Holland A. Binding of STIL to Plk4 activates kinase activity to promote centriole assembly. J Cell Biol. 2015;209:863-78 pubmed 出版商
  • 免疫细胞化学; 人类; 1:5000; 图 7
Whalley H, Porter A, Diamantopoulou Z, White G, Castañeda Saucedo E, Malliri A. Cdk1 phosphorylates the Rac activator Tiam1 to activate centrosomal Pak and promote mitotic spindle formation. Nat Commun. 2015;6:7437 pubmed 出版商
  • 免疫印迹; 人类; 图 7
Taylor S, Dantas T, Durán I, Wu S, Lachman R, Nelson S, et al. Mutations in DYNC2LI1 disrupt cilia function and cause short rib polydactyly syndrome. Nat Commun. 2015;6:7092 pubmed 出版商
  • 免疫细胞化学; 小鼠; 1:500; 图 s7a,b
Yang N, Li L, Eguether T, Sundberg J, Pazour G, Chen J. Intraflagellar transport 27 is essential for hedgehog signaling but dispensable for ciliogenesis during hair follicle morphogenesis. Development. 2015;142:2194-202 pubmed 出版商
  • 免疫印迹; 人类; 1:10,000; 图 2
Morchoisne Bolhy S, Geoffroy M, Bouhlel I, Alves A, Audugé N, Baudin X, et al. Intranuclear dynamics of the Nup107-160 complex. Mol Biol Cell. 2015;26:2343-56 pubmed 出版商
  • 免疫印迹; 小鼠; 1:5000; 图 6
Liu C, Yu Y, Liu F, Wei X, Wrobel J, Gunawardena H, et al. A chromatin activity-based chemoproteomic approach reveals a transcriptional repressome for gene-specific silencing. Nat Commun. 2014;5:5733 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 图 3
  • 免疫印迹; 人类; 图 9
Gegg M, Böttcher A, Burtscher I, Hasenoeder S, Van Campenhout C, Aichler M, et al. Flattop regulates basal body docking and positioning in mono- and multiciliated cells. elife. 2014;3: pubmed 出版商
  • 免疫细胞化学; 人类
Mannino M, Gomez Roman N, Hochegger H, Chalmers A. Differential sensitivity of Glioma stem cells to Aurora kinase A inhibitors: implications for stem cell mitosis and centrosome dynamics. Stem Cell Res. 2014;13:135-43 pubmed 出版商
  • 免疫细胞化学; 人类
Mäki Jouppila J, Laine L, Rehnberg J, Narvi E, Tiikkainen P, Hukasova E, et al. Centmitor-1, a novel acridinyl-acetohydrazide, possesses similar molecular interaction field and antimitotic cellular phenotype as rigosertib, on 01910.Na. Mol Cancer Ther. 2014;13:1054-66 pubmed 出版商
  • 免疫细胞化学; 人类
Li L, Yang G, Ren C, Tanimoto R, Hirayama T, Wang J, et al. Glioma pathogenesis-related protein 1 induces prostate cancer cell death through Hsc70-mediated suppression of AURKA and TPX2. Mol Oncol. 2013;7:484-96 pubmed 出版商
  • 免疫组化; 大鼠; 1:500
Garcia Ovejero D, Arevalo Martin A, Paniagua Torija B, Sierra Palomares Y, Molina Holgado E. A cell population that strongly expresses the CB1 cannabinoid receptor in the ependyma of the rat spinal cord. J Comp Neurol. 2013;521:233-51 pubmed 出版商
Charruyer A, Weisenberger T, Li H, Khalifa A, Schroeder A, Belzer A, et al. Decreased p53 is associated with a decline in asymmetric stem cell self-renewal in aged human epidermis. Aging Cell. 2021;20:e13310 pubmed 出版商
Ordóñez A, Fernández B, Fdez E, Romo Lozano M, Madero Pérez J, Lobbestael E, et al. RAB8, RAB10 and RILPL1 contribute to both LRRK2 kinase-mediated centrosomal cohesion and ciliogenesis deficits. Hum Mol Genet. 2019;: pubmed 出版商
Kunova Bosakova M, Nita A, Gregor T, Varecha M, Gudernová I, Fafilek B, et al. Fibroblast growth factor receptor influences primary cilium length through an interaction with intestinal cell kinase. Proc Natl Acad Sci U S A. 2019;: pubmed 出版商
Choi Y, Halbritter J, Braun D, Schueler M, Schapiro D, Rim J, et al. Mutations of ADAMTS9 Cause Nephronophthisis-Related Ciliopathy. Am J Hum Genet. 2019;104:45-54 pubmed 出版商
Chin A, Worley K, Ray P, Kaur G, Fan J, Wan L. Epithelial Cell Chirality Revealed by Three-Dimensional Spontaneous Rotation. Proc Natl Acad Sci U S A. 2018;115:12188-12193 pubmed 出版商
Revinski D, Zaragosi L, Boutin C, Ruiz García S, Deprez M, Thomé V, et al. CDC20B is required for deuterosome-mediated centriole production in multiciliated cells. Nat Commun. 2018;9:4668 pubmed 出版商
Mehsen H, Boudreau V, Garrido D, Bourouh M, Larouche M, Maddox P, et al. PP2A-B55 promotes nuclear envelope reformation after mitosis in Drosophila. J Cell Biol. 2018;217:4106-4123 pubmed 出版商
Zhang F, Wang Y, Wang T, Yao L, Lam S, Huang X, et al. cTAGE5/MEA6 plays a critical role in neuronal cellular components trafficking and brain development. Proc Natl Acad Sci U S A. 2018;115:E9449-E9458 pubmed 出版商
Kratz K, de Lange T. Protection of telomeres 1 proteins POT1a and POT1b can repress ATR signaling by RPA exclusion, but binding to CST limits ATR repression by POT1b. J Biol Chem. 2018;293:14384-14392 pubmed 出版商
Wang L, Wrobel J, Xie L, Li D, Zurlo G, Shen H, et al. Novel RNA-Affinity Proteogenomics Dissects Tumor Heterogeneity for Revealing Personalized Markers in Precision Prognosis of Cancer. Cell Chem Biol. 2018;25:619-633.e5 pubmed 出版商
Madero Pérez J, Fdez E, Fernández B, Lara Ordóñez A, Blanca Ramírez M, Gomez Suaga P, et al. Parkinson disease-associated mutations in LRRK2 cause centrosomal defects via Rab8a phosphorylation. Mol Neurodegener. 2018;13:3 pubmed 出版商
Lewis T, Zareba M, Link B, Besharse J. Cone myoid elongation involves unidirectional microtubule movement mediated by dynein-1. Mol Biol Cell. 2018;29:180-190 pubmed 出版商
Machado C, Nagai M, Lyra C, Reis Silva T, Xavier A, Glezer I, et al. Conditional Deletion of Ric-8b in Olfactory Sensory Neurons Leads to Olfactory Impairment. J Neurosci. 2017;37:12202-12213 pubmed 出版商
Yang Z, Maciejowski J, de Lange T. Nuclear Envelope Rupture Is Enhanced by Loss of p53 or Rb. Mol Cancer Res. 2017;15:1579-1586 pubmed 出版商
Carvalhal S, Stevense M, Koehler K, Naumann R, Huebner A, Jessberger R, et al. ALADIN is required for the production of fertile mouse oocytes. Mol Biol Cell. 2017;28:2470-2478 pubmed 出版商
Bestul A, Yu Z, Unruh J, Jaspersen S. Molecular model of fission yeast centrosome assembly determined by superresolution imaging. J Cell Biol. 2017;216:2409-2424 pubmed 出版商
Lewis T, Kundinger S, Pavlovich A, Bostrom J, Link B, Besharse J. Cos2/Kif7 and Osm-3/Kif17 regulate onset of outer segment development in zebrafish photoreceptors through distinct mechanisms. Dev Biol. 2017;425:176-190 pubmed 出版商
Meitinger F, Anzola J, Kaulich M, Richardson A, Stender J, Benner C, et al. 53BP1 and USP28 mediate p53 activation and G1 arrest after centrosome loss or extended mitotic duration. J Cell Biol. 2016;214:155-66 pubmed 出版商
Brown J, Petersen A, Zhong L, Himelright M, Murphy J, Walikonis R, et al. Bidirectional regulation of synaptic transmission by BRAG1/IQSEC2 and its requirement in long-term depression. Nat Commun. 2016;7:11080 pubmed 出版商
Xiao T, Wongtrakoongate P, TRAINOR C, Felsenfeld G. CTCF Recruits Centromeric Protein CENP-E to the Pericentromeric/Centromeric Regions of Chromosomes through Unusual CTCF-Binding Sites. Cell Rep. 2015;12:1704-14 pubmed 出版商
Zahnleiter D, Hauer N, Kessler K, Uebe S, Sugano Y, Neuhauss S, et al. MAP4-dependent regulation of microtubule formation affects centrosome, cilia, and Golgi architecture as a central mechanism in growth regulation. Hum Mutat. 2015;36:87-97 pubmed 出版商
Skene P, Hernandez A, Groudine M, Henikoff S. The nucleosomal barrier to promoter escape by RNA polymerase II is overcome by the chromatin remodeler Chd1. elife. 2014;3:e02042 pubmed 出版商
Hell M, Duda M, Weber T, Moch H, Krek W. Tumor suppressor VHL functions in the control of mitotic fidelity. Cancer Res. 2014;74:2422-31 pubmed 出版商
Kotoshiba S, Gopinathan L, Pfeiffenberger E, Rahim A, Vardy L, Nakayama K, et al. p27 is regulated independently of Skp2 in the absence of Cdk2. Biochim Biophys Acta. 2014;1843:436-45 pubmed 出版商
Peng C, Wikramanayake A. Differential regulation of disheveled in a novel vegetal cortical domain in sea urchin eggs and embryos: implications for the localized activation of canonical Wnt signaling. PLoS ONE. 2013;8:e80693 pubmed 出版商
Hashizume C, Moyori A, Kobayashi A, Yamakoshi N, Endo A, Wong R. Nucleoporin Nup62 maintains centrosome homeostasis. Cell Cycle. 2013;12:3804-16 pubmed 出版商
Kajitani N, Satsuka A, Yoshida S, Sakai H. HPV18 E1^E4 is assembled into aggresome-like compartment and involved in sequestration of viral oncoproteins. Front Microbiol. 2013;4:251 pubmed 出版商
Telkoparan P, Erkek S, Yaman E, Alotaibi H, Bayık D, Tazebay U. Coiled-coil domain containing protein 124 is a novel centrosome and midbody protein that interacts with the Ras-guanine nucleotide exchange factor 1B and is involved in cytokinesis. PLoS ONE. 2013;8:e69289 pubmed 出版商
Blanchette P, Wimmer P, Dallaire F, Cheng C, Branton P. Aggresome formation by the adenoviral protein E1B55K is not conserved among adenovirus species and is not required for efficient degradation of nuclear substrates. J Virol. 2013;87:4872-81 pubmed 出版商
Valdés Sánchez L, De la Cerda B, Diaz Corrales F, Massalini S, Chakarova C, Wright A, et al. ATR localizes to the photoreceptor connecting cilium and deficiency leads to severe photoreceptor degeneration in mice. Hum Mol Genet. 2013;22:1507-15 pubmed 出版商
Gavvovidis I, Rost I, Trimborn M, Kaiser F, Purps J, Wiek C, et al. A novel MCPH1 isoform complements the defective chromosome condensation of human MCPH1-deficient cells. PLoS ONE. 2012;7:e40387 pubmed 出版商
Jo S, Kallo I, Bardóczi Z, Arrojo e Drigo R, Zeöld A, Liposits Z, et al. Neuronal hypoxia induces Hsp40-mediated nuclear import of type 3 deiodinase as an adaptive mechanism to reduce cellular metabolism. J Neurosci. 2012;32:8491-500 pubmed 出版商
Mok M, Henderson B. The in vivo dynamic interplay of MDC1 and 53BP1 at DNA damage-induced nuclear foci. Int J Biochem Cell Biol. 2012;44:1398-409 pubmed 出版商
Jaglarz M, Bazile F, Laskowska K, Polanski Z, Chesnel F, Borsuk E, et al. Association of TCTP with centrosome and microtubules. Biochem Res Int. 2012;2012:541906 pubmed 出版商
Liapis E, Sandiford S, Wang Q, Gaidosh G, Motti D, Levay K, et al. Subcellular localization of regulator of G protein signaling RGS7 complex in neurons and transfected cells. J Neurochem. 2012;122:568-81 pubmed 出版商
Ribas V, Gonçalves B, Linden R, Chiarini L. Activation of c-Jun N-terminal kinase (JNK) during mitosis in retinal progenitor cells. PLoS ONE. 2012;7:e34483 pubmed 出版商
Alfaro Cervello C, Soriano Navarro M, Mirzadeh Z, Alvarez Buylla A, Garcia Verdugo J. Biciliated ependymal cell proliferation contributes to spinal cord growth. J Comp Neurol. 2012;520:3528-52 pubmed 出版商
Roundhill E, Burchill S. Detection and characterisation of multi-drug resistance protein 1 (MRP-1) in human mitochondria. Br J Cancer. 2012;106:1224-33 pubmed 出版商
Shi Y, Kirwan P, Smith J, Robinson H, Livesey F. Human cerebral cortex development from pluripotent stem cells to functional excitatory synapses. Nat Neurosci. 2012;15:477-86, S1 pubmed 出版商
Kim W, Kim R, Park G, Park J, Kim J. Deficiency of H3K79 histone methyltransferase Dot1-like protein (DOT1L) inhibits cell proliferation. J Biol Chem. 2012;287:5588-99 pubmed 出版商
Castiel A, Visochek L, Mittelman L, Dantzer F, Izraeli S, Cohen Armon M. A phenanthrene derived PARP inhibitor is an extra-centrosomes de-clustering agent exclusively eradicating human cancer cells. BMC Cancer. 2011;11:412 pubmed 出版商
Heldens L, Hensen S, Onnekink C, van Genesen S, Dirks R, Lubsen N. An atypical unfolded protein response in heat shocked cells. PLoS ONE. 2011;6:e23512 pubmed 出版商
Harris R, Weiss J, Jameson J. Male hypogonadism and germ cell loss caused by a mutation in Polo-like kinase 4. Endocrinology. 2011;152:3975-85 pubmed 出版商
Bakircioglu M, Carvalho O, Khurshid M, Cox J, Tuysuz B, Barak T, et al. The essential role of centrosomal NDE1 in human cerebral cortex neurogenesis. Am J Hum Genet. 2011;88:523-35 pubmed 出版商
Amorim M, Bruce E, Read E, Foeglein A, Mahen R, Stuart A, et al. A Rab11- and microtubule-dependent mechanism for cytoplasmic transport of influenza A virus viral RNA. J Virol. 2011;85:4143-56 pubmed 出版商
Castiel A, Danieli M, David A, Moshkovitz S, Aplan P, Kirsch I, et al. The Stil protein regulates centrosome integrity and mitosis through suppression of Chfr. J Cell Sci. 2011;124:532-9 pubmed 出版商
Nicholas A, Khurshid M, Desir J, Carvalho O, Cox J, Thornton G, et al. WDR62 is associated with the spindle pole and is mutated in human microcephaly. Nat Genet. 2010;42:1010-4 pubmed 出版商
Staals R, Bronkhorst A, Schilders G, Slomovic S, Schuster G, Heck A, et al. Dis3-like 1: a novel exoribonuclease associated with the human exosome. EMBO J. 2010;29:2358-67 pubmed 出版商
Shang Z, Huang B, Xu Q, Zhang S, Fan R, Liu X, et al. Inactivation of DNA-dependent protein kinase leads to spindle disruption and mitotic catastrophe with attenuated checkpoint protein 2 Phosphorylation in response to DNA damage. Cancer Res. 2010;70:3657-66 pubmed 出版商
Singla V, Romaguera Ros M, Garcia Verdugo J, Reiter J. Ofd1, a human disease gene, regulates the length and distal structure of centrioles. Dev Cell. 2010;18:410-24 pubmed 出版商
Holland A, Lan W, Niessen S, Hoover H, Cleveland D. Polo-like kinase 4 kinase activity limits centrosome overduplication by autoregulating its own stability. J Cell Biol. 2010;188:191-8 pubmed 出版商
Gilmartin A, Bleam M, Richter M, Erskine S, Kruger R, Madden L, et al. Distinct concentration-dependent effects of the polo-like kinase 1-specific inhibitor GSK461364A, including differential effect on apoptosis. Cancer Res. 2009;69:6969-77 pubmed 出版商
Mielgo A, Torres V, Clair K, Barbero S, Stupack D. Paclitaxel promotes a caspase 8-mediated apoptosis through death effector domain association with microtubules. Oncogene. 2009;28:3551-62 pubmed 出版商
Zheng P, Dean J. Role of Filia, a maternal effect gene, in maintaining euploidy during cleavage-stage mouse embryogenesis. Proc Natl Acad Sci U S A. 2009;106:7473-8 pubmed 出版商
Marion V, Stoetzel C, Schlicht D, Messaddeq N, Koch M, Flori E, et al. Transient ciliogenesis involving Bardet-Biedl syndrome proteins is a fundamental characteristic of adipogenic differentiation. Proc Natl Acad Sci U S A. 2009;106:1820-5 pubmed 出版商
Mirzadeh Z, Merkle F, Soriano Navarro M, Garcia Verdugo J, Alvarez Buylla A. Neural stem cells confer unique pinwheel architecture to the ventricular surface in neurogenic regions of the adult brain. Cell Stem Cell. 2008;3:265-78 pubmed 出版商
Xu B, Hao Z, Jha K, Zhang Z, Urekar C, Digilio L, et al. TSKS concentrates in spermatid centrioles during flagellogenesis. Dev Biol. 2008;319:201-10 pubmed 出版商
Warby S, Doty C, Graham R, Carroll J, Yang Y, Singaraja R, et al. Activated caspase-6 and caspase-6-cleaved fragments of huntingtin specifically colocalize in the nucleus. Hum Mol Genet. 2008;17:2390-404 pubmed 出版商
de Boer L, Oakes V, Beamish H, Giles N, Stevens F, Somodevilla Torres M, et al. Cyclin A/cdk2 coordinates centrosomal and nuclear mitotic events. Oncogene. 2008;27:4261-8 pubmed 出版商
Yoneda Kato N, Kato J. Shuttling imbalance of MLF1 results in p53 instability and increases susceptibility to oncogenic transformation. Mol Cell Biol. 2008;28:422-34 pubmed
Caldwell C, Green R, Kaplan K. APC mutations lead to cytokinetic failures in vitro and tetraploid genotypes in Min mice. J Cell Biol. 2007;178:1109-20 pubmed
Yu S, Eastman S, Linial M. Foamy virus capsid assembly occurs at a pericentriolar region through a cytoplasmic targeting/retention signal in Gag. Traffic. 2006;7:966-77 pubmed
Ferrer I, Carmona M, Blanco R, Moreno D, Torrejón Escribano B, Olive M. Involvement of clusterin and the aggresome in abnormal protein deposits in myofibrillar myopathies and inclusion body myositis. Brain Pathol. 2005;15:101-8 pubmed
产品信息
目录号 :
ab11316
ItemName :
抗γ-微管抗体[GTU-88]
产品类型 :
抗体
宿主物种 :
小鼠
克隆性 :
单克隆
共轭标签 :
未共轭
克隆名称 :
GTU-88
规格 :
100微升
物种摘要 :
Chk, Cow, Dog, Hm, Hu, InMtj, Ms, Rat, Xl
纯度 :
Proprietary Purification
应用摘要 :
ELISA, ICC, ICC/IF, IHC-FoFr, IHC-FrFl, IHC-P, WB
公司信息
艾博抗(上海)贸易有限公司
上海市浦东新区伽利略路338号5幢4层5401室
cn.technical@abcam.com
http://www.abcam.cn
400-628-6880 86-21-5110 5938
公司总部: 英国
Abcam是全球知名的生命科学研究领域产品提供商,产品涵盖一抗、二抗、蛋白、多肽及ELISA kit。