产品简要
公司名称 :
艾博抗(上海)贸易有限公司
其他品牌 :
Epitomics, Ascent Scientific, MitoSciences
产品类型 :
抗体
产品名称 :
抗VCP抗体[5]
目录 :
ab11433
规格 :
50微升
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
5
反应物种 :
人类, 小鼠, 大鼠, ,
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学, 免疫沉淀, 流式细胞仪, 免疫组化-石蜡切片, 免疫组化-冰冻切片
文章摘录数: 25
出版应用/物种/样本/稀释参考文献
  • 免疫细胞化学; 人类; 图 4a
Yasuda S, Tsuchiya H, Kaiho A, Guo Q, Ikeuchi K, Endo A, et al. Stress- and ubiquitylation-dependent phase separation of the proteasome. Nature. 2020;578:296-300 pubmed 出版商
  • 免疫印迹; 小鼠; 1:2000; 图 6c
Bayindir Buchhalter I, Wolff G, Lerch S, Sijmonsma T, Schuster M, Gronych J, et al. Cited4 is a sex-biased mediator of the antidiabetic glitazone response in adipocyte progenitors. EMBO Mol Med. 2018;10: pubmed 出版商
  • 免疫沉淀; 人类; 图 7a
Glaeser K, Urban M, Fenech E, Voloshanenko O, Kranz D, Lari F, et al. ERAD-dependent control of the Wnt secretory factor Evi. EMBO J. 2018;37: pubmed 出版商
  • 免疫沉淀; 人类; 图 s2a
Nguyen T, Li J, Lu C, Mamrosh J, Lu G, Cathers B, et al. p97/VCP promotes degradation of CRBN substrate glutamine synthetase and neosubstrates. Proc Natl Acad Sci U S A. 2017;114:3565-3571 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 6
Franz A, Pirson P, Pilger D, Halder S, Achuthankutty D, Kashkar H, et al. Chromatin-associated degradation is defined by UBXN-3/FAF1 to safeguard DNA replication fork progression. Nat Commun. 2016;7:10612 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:250; 图 3
  • 免疫印迹; 小鼠; 1:2000; 图 2
  • 免疫印迹; 人类; 1:2000; 图 4
Fusser M, Kernstock S, Aileni V, Egge Jacobsen W, Falnes P, Klungland A. Lysine Methylation of the Valosin-Containing Protein (VCP) Is Dispensable for Development and Survival of Mice. PLoS ONE. 2015;10:e0141472 pubmed 出版商
  • 免疫组化; 人类; 图 3c
Berry G, Asokan A. Chemical Modulation of Endocytic Sorting Augments Adeno-associated Viral Transduction. J Biol Chem. 2016;291:939-47 pubmed 出版商
  • 免疫印迹; 小鼠; 图 s3
Okun J, Conway S, Schmidt K, Schumacher J, Wang X, de Guia R, et al. Molecular regulation of urea cycle function by the liver glucocorticoid receptor. Mol Metab. 2015;4:732-40 pubmed 出版商
  • 免疫组化-石蜡切片; 犬; 1:4000; 图 1
  • 免疫印迹; 犬; 图 1
Nadeau M, Rico C, Tsoi M, Vivancos M, Filimon S, Paquet M, et al. Pharmacological targeting of valosin containing protein (VCP) induces DNA damage and selectively kills canine lymphoma cells. BMC Cancer. 2015;15:479 pubmed 出版商
  • 免疫印迹; 小鼠; 图 3
Stoy C, Sundaram A, Rios Garcia M, Wang X, Seibert O, Zota A, et al. Transcriptional co-factor Transducin beta-like (TBL) 1 acts as a checkpoint in pancreatic cancer malignancy. EMBO Mol Med. 2015;7:1048-62 pubmed 出版商
  • 免疫印迹; 小鼠
Mössenböck K, Vegiopoulos A, Rose A, Sijmonsma T, Herzig S, Schafmeier T. Browning of white adipose tissue uncouples glucose uptake from insulin signaling. PLoS ONE. 2014;9:e110428 pubmed 出版商
Parzych K, Saavedra García P, Valbuena G, Al Sadah H, Robinson M, Penfold L, et al. The coordinated action of VCP/p97 and GCN2 regulates cancer cell metabolism and proteostasis during nutrient limitation. Oncogene. 2019;38:3216-3231 pubmed 出版商
McLelland G, Goiran T, Yi W, Dorval G, Chen C, Lauinger N, et al. Mfn2 ubiquitination by PINK1/parkin gates the p97-dependent release of ER from mitochondria to drive mitophagy. elife. 2018;7: pubmed 出版商
Thinon E, Fernandez J, Molina H, Hang H. Selective Enrichment and Direct Analysis of Protein S-Palmitoylation Sites. J Proteome Res. 2018;17:1907-1922 pubmed 出版商
Baranes Bachar K, Levy Barda A, Oehler J, Reid D, Soria Bretones I, Voss T, et al. The Ubiquitin E3/E4 Ligase UBE4A Adjusts Protein Ubiquitylation and Accumulation at Sites of DNA Damage, Facilitating Double-Strand Break Repair. Mol Cell. 2018;69:866-878.e7 pubmed 出版商
Skrott Z, Mistrik M, Andersen K, Friis S, Majera D, Gursky J, et al. Alcohol-abuse drug disulfiram targets cancer via p97 segregase adaptor NPL4. Nature. 2017;552:194-199 pubmed 出版商
van den Berg D, Azzarelli R, Oishi K, Martynoga B, Urbán N, Dekkers D, et al. Nipbl Interacts with Zfp609 and the Integrator Complex to Regulate Cortical Neuron Migration. Neuron. 2017;93:348-361 pubmed 出版商
Xue L, Blythe E, Freiberger E, Mamrosh J, Hebert A, Reitsma J, et al. Valosin-containing protein (VCP)-Adaptor Interactions are Exceptionally Dynamic and Subject to Differential Modulation by a VCP Inhibitor. Mol Cell Proteomics. 2016;15:2970-86 pubmed 出版商
Fuhrmeister J, Zota A, Sijmonsma T, Seibert O, Cıngır Å, Schmidt K, et al. Fasting-induced liver GADD45β restrains hepatic fatty acid uptake and improves metabolic health. EMBO Mol Med. 2016;8:654-69 pubmed 出版商
Parrish R, Buckingham S, Mascia K, Johnson J, Matyjasik M, Lockhart R, et al. Methionine increases BDNF DNA methylation and improves memory in epilepsy. Ann Clin Transl Neurol. 2015;2:401-16 pubmed 出版商
Wöltje K, Jabs M, Fischer A. Serum induces transcription of Hey1 and Hey2 genes by Alk1 but not Notch signaling in endothelial cells. PLoS ONE. 2015;10:e0120547 pubmed 出版商
Ayaki T, Ito H, Fukushima H, Inoue T, Kondo T, Ikemoto A, et al. Immunoreactivity of valosin-containing protein in sporadic amyotrophic lateral sclerosis and in a case of its novel mutant. Acta Neuropathol Commun. 2014;2:172 pubmed 出版商
Penno C, Morgan S, Rose A, Herzig S, Lavery G, Odermatt A. 11?-Hydroxysteroid dehydrogenase-1 is involved in bile acid homeostasis by modulating fatty acid transport protein-5 in the liver of mice. Mol Metab. 2014;3:554-64 pubmed 出版商
Laguë M, Romieu Mourez R, Bonneil E, Boyer A, Pouletty N, Mes Masson A, et al. Proteomic profiling of a mouse model for ovarian granulosa cell tumor identifies VCP as a highly sensitive serum tumor marker in several human cancers. PLoS ONE. 2012;7:e42470 pubmed 出版商
Sahab Z, Hall M, Zhang L, Cheema A, Byers S. Tumor Suppressor RARRES1 Regulates DLG2, PP2A, VCP, EB1, and Ankrd26. J Cancer. 2010;1:14-22 pubmed
产品信息
目录号 :
ab11433
ItemName :
抗VCP抗体[5]
产品类型 :
抗体
宿主物种 :
小鼠
克隆性 :
单克隆
共轭标签 :
未共轭
克隆名称 :
5
规格 :
50微升
物种摘要 :
Cow, Hu, Ms, Rat, Shp
纯度 :
腹水
应用摘要 :
ELISA, Flow Cyt, ICC, ICC/IF, IHC-Fr, IHC-P, IP, WB
公司信息
艾博抗(上海)贸易有限公司
上海市浦东新区伽利略路338号5幢4层5401室
cn.technical@abcam.com
http://www.abcam.cn
400-628-6880 86-21-5110 5938
公司总部: 英国
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