产品简要
公司名称 :
艾博抗(上海)贸易有限公司
其他品牌 :
Epitomics, Ascent Scientific, MitoSciences
产品类型 :
抗体
产品名称 :
抗alpha突触核蛋白抗体[MJFR1]
目录 :
ab138501
规格 :
100微升
克隆性 :
单克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
克隆名称 :
MJFR1
反应物种 :
人类, 小鼠, 猕猴
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫细胞化学, 免疫沉淀, 流式细胞仪, 免疫组化-石蜡切片
文章摘录数: 20
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 小鼠; 1:2000
Zhang C, Zhao M, Wang B, Su Z, Guo B, Qin L, et al. The Nrf2-NLRP3-caspase-1 axis mediates the neuroprotective effects of Celastrol in Parkinson's disease. Redox Biol. 2021;47:102134 pubmed 出版商
  • 免疫细胞化学; 人类; 1:1000; 图 e4a
  • 酶联免疫吸附测定; 人类; 1 ug/ml; 图 3b
  • 免疫印迹; 人类; 1:1000; 图 3e
Emmenegger M, De Cecco E, Hruska Plochan M, Eninger T, Schneider M, Barth M, et al. LAG3 is not expressed in human and murine neurons and does not modulate α-synucleinopathies. EMBO Mol Med. 2021;13:e14745 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 5h
Bengoa Vergniory N, Faggiani E, Ramos Gonzalez P, Kirkiz E, Connor Robson N, Brown L, et al. CLR01 protects dopaminergic neurons in vitro and in mouse models of Parkinson's disease. Nat Commun. 2020;11:4885 pubmed 出版商
  • 免疫组化-石蜡切片; 猕猴; 1:200; 图 s6a
Metzger J, Matsoff H, Zinnen A, Fleddermann R, Bondarenko V, Simmons H, et al. Post mortem evaluation of inflammation, oxidative stress, and PPARγ activation in a nonhuman primate model of cardiac sympathetic neurodegeneration. PLoS ONE. 2020;15:e0226999 pubmed 出版商
  • 免疫印迹; 人类; 图 e7a
Burmann B, Gerez J, Matečko Burmann I, Campioni S, Kumari P, Ghosh D, et al. Regulation of α-synuclein by chaperones in mammalian cells. Nature. 2020;577:127-132 pubmed 出版商
  • 免疫印迹; 人类; 1:4000; 图 6a
Angelova D, Brown D. Model Senescent Microglia Induce Disease Related Changes in α-Synuclein Expression and Activity. Biomolecules. 2018;8: pubmed 出版商
Ramalingam N, Dettmer U. Temperature is a key determinant of alpha- and beta-synuclein membrane interactions in neurons. J Biol Chem. 2021;:100271 pubmed 出版商
Sheng L, Stewart T, Yang D, Thorland E, Soltys D, Aro P, et al. Erythrocytic α-synuclein contained in microvesicles regulates astrocytic glutamate homeostasis: a new perspective on Parkinson's disease pathogenesis. Acta Neuropathol Commun. 2020;8:102 pubmed 出版商
Choi I, Zhang Y, Seegobin S, Pruvost M, Wang Q, Purtell K, et al. Microglia clear neuron-released α-synuclein via selective autophagy and prevent neurodegeneration. Nat Commun. 2020;11:1386 pubmed 出版商
Pérez Rodríguez D, Kalyva M, Leija Salazar M, Lashley T, Tarabichi M, Chelban V, et al. Investigation of somatic CNVs in brains of synucleinopathy cases using targeted SNCA analysis and single cell sequencing. Acta Neuropathol Commun. 2019;7:219 pubmed 出版商
Elfarrash S, Jensen N, Ferreira N, Betzer C, Thevathasan J, Diekmann R, et al. Organotypic slice culture model demonstrates inter-neuronal spreading of alpha-synuclein aggregates. Acta Neuropathol Commun. 2019;7:213 pubmed 出版商
Van Den Berge N, Ferreira N, Gram H, Mikkelsen T, Alstrup A, Casadei N, et al. Evidence for bidirectional and trans-synaptic parasympathetic and sympathetic propagation of alpha-synuclein in rats. Acta Neuropathol. 2019;: pubmed 出版商
McGlinchey R, Lacy S, Huffer K, Tayebi N, Sidransky E, Lee J. C-terminal α-synuclein truncations are linked to cysteine cathepsin activity in Parkinson's disease. J Biol Chem. 2019;294:9973-9984 pubmed 出版商
Pluvinage J, Haney M, Smith B, Sun J, Iram T, Bonanno L, et al. CD22 blockade restores homeostatic microglial phagocytosis in ageing brains. Nature. 2019;568:187-192 pubmed 出版商
Bieri G, Brahic M, Bousset L, Couthouis J, Kramer N, Ma R, et al. LRRK2 modifies α-syn pathology and spread in mouse models and human neurons. Acta Neuropathol. 2019;137:961-980 pubmed 出版商
Hu D, Sun X, Liao X, Zhang X, Zarabi S, Schimmer A, et al. Alpha-synuclein suppresses mitochondrial protease ClpP to trigger mitochondrial oxidative damage and neurotoxicity. Acta Neuropathol. 2019;137:939-960 pubmed 出版商
Cliffe R, Sang J, Kundel F, Finley D, Klenerman D, Ye Y. Filamentous Aggregates Are Fragmented by the Proteasome Holoenzyme. Cell Rep. 2019;26:2140-2149.e3 pubmed 出版商
Adams J, Feuerborn M, Molina J, Wilden A, Adhikari B, Budden T, et al. Autophagy-lysosome pathway alterations and alpha-synuclein up-regulation in the subtype of neuronal ceroid lipofuscinosis, CLN5 disease. Sci Rep. 2019;9:151 pubmed 出版商
Kantor B, Tagliafierro L, Gu J, Zamora M, Ilich E, Grenier C, et al. Downregulation of SNCA Expression by Targeted Editing of DNA Methylation: A Potential Strategy for Precision Therapy in PD. Mol Ther. 2018;26:2638-2649 pubmed 出版商
Turriani E, Lázaro D, Ryazanov S, Leonov A, Giese A, Schön M, et al. Treatment with diphenyl-pyrazole compound anle138b/c reveals that α-synuclein protects melanoma cells from autophagic cell death. Proc Natl Acad Sci U S A. 2017;114:E4971-E4977 pubmed 出版商
产品信息
目录号 :
ab138501
ItemName :
抗alpha突触核蛋白抗体[MJFR1]
类别 :
抗体
宿主 :
克隆性 :
单克隆
共轭标签 :
未共轭
克隆名称 :
MJFR1
规格 :
100微升
物种摘要 :
Dm, Hu
应用摘要 :
ELISA, Flow Cyt, ICC/IF, IHC-P, IP, WB
公司信息
艾博抗(上海)贸易有限公司
上海市浦东新区伽利略路338号5幢4层5401室
cn.technical@abcam.com
http://www.abcam.cn
400-628-6880 86-21-5110 5938
公司总部: 英国
Abcam是全球知名的生命科学研究领域产品提供商,产品涵盖一抗、二抗、蛋白、多肽及ELISA kit。