产品简要
公司名称 :
艾博抗(上海)贸易有限公司
其他品牌 :
Epitomics, Ascent Scientific, MitoSciences
产品类型 :
抗体
产品名称 :
抗Mus81抗体[MTA30 2G10/3]
目录 :
ab14387
规格 :
100微克
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
MTA30 2G10/3
反应物种 :
人类
应用 :
免疫印迹, 免疫细胞化学, 免疫沉淀, 流式细胞仪, 染色质免疫沉淀 , 免疫印迹基因敲除验证
文章摘录数: 20
出版应用/物种/样本/稀释参考文献
  • 免疫印迹基因敲除验证; 人类; 1:500; 图 8a
Baxley R, Leung W, Schmit M, Matson J, Yin L, Oram M, et al. Bi-allelic MCM10 variants associated with immune dysfunction and cardiomyopathy cause telomere shortening. Nat Commun. 2021;12:1626 pubmed 出版商
  • 免疫印迹; 人类; 图 5g
Xu M, Qin J, Wang L, Lee H, Kao C, Liu D, et al. Nuclear receptors regulate alternative lengthening of telomeres through a novel noncanonical FANCD2 pathway. Sci Adv. 2019;5:eaax6366 pubmed 出版商
  • 免疫印迹; 人类; 图 5f
Meisenberg C, Ashour M, El Shafie L, Liao C, Hodgson A, Pilborough A, et al. Epigenetic changes in histone acetylation underpin resistance to the topoisomerase I inhibitor irinotecan. Nucleic Acids Res. 2017;45:1159-1176 pubmed 出版商
  • 免疫印迹; 人类; 图 5c
Jo U, Cai W, Wang J, Kwon Y, D Andrea A, Kim H. PCNA-Dependent Cleavage and Degradation of SDE2 Regulates Response to Replication Stress. PLoS Genet. 2016;12:e1006465 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 2
Xing M, Wang X, Palmai Pallag T, Shen H, Helleday T, Hickson I, et al. Acute MUS81 depletion leads to replication fork slowing and a constitutive DNA damage response. Oncotarget. 2015;6:37638-46 pubmed 出版商
  • 免疫印迹基因敲除验证; 人类; 1:2000; 图 3
Fu H, Martin M, Regairaz M, Huang L, You Y, Lin C, et al. The DNA repair endonuclease Mus81 facilitates fast DNA replication in the absence of exogenous damage. Nat Commun. 2015;6:6746 pubmed 出版商
  • 染色质免疫沉淀 ; 人类; 1:1000; 图 4
Thangavel S, Berti M, Levikova M, Pinto C, Gomathinayagam S, Vujanovic M, et al. DNA2 drives processing and restart of reversed replication forks in human cells. J Cell Biol. 2015;208:545-62 pubmed 出版商
  • 免疫印迹; 人类; 1:200; 图 4a
Saint Léger A, Koelblen M, Civitelli L, Bah A, Djerbi N, Giraud Panis M, et al. The basic N-terminal domain of TRF2 limits recombination endonuclease action at human telomeres. Cell Cycle. 2014;13:2469-74 pubmed 出版商
  • 免疫印迹; 人类; 图 2
Laguette N, Brégnard C, Hue P, Basbous J, Yatim A, Larroque M, et al. Premature activation of the SLX4 complex by Vpr promotes G2/M arrest and escape from innate immune sensing. Cell. 2014;156:134-45 pubmed 出版商
  • 免疫沉淀; 人类
  • 免疫印迹; 人类
Stoepker C, Hain K, Schuster B, Hilhorst Hofstee Y, Rooimans M, Steltenpool J, et al. SLX4, a coordinator of structure-specific endonucleases, is mutated in a new Fanconi anemia subtype. Nat Genet. 2011;43:138-41 pubmed 出版商
Rickman K, Noonan R, Lach F, Sridhar S, Wang A, Abhyankar A, et al. Distinct roles of BRCA2 in replication fork protection in response to hydroxyurea and DNA interstrand cross-links. Genes Dev. 2020;34:832-846 pubmed 出版商
Panier S, Maric M, Hewitt G, Mason Osann E, Gali H, Dai A, et al. SLX4IP Antagonizes Promiscuous BLM Activity during ALT Maintenance. Mol Cell. 2019;76:27-43.e11 pubmed 出版商
MacGregor T, Carter R, Gillies R, Findlay J, Kartsonaki C, Castro Giner F, et al. Translational study identifies XPF and MUS81 as predictive biomarkers for oxaliplatin-based peri-operative chemotherapy in patients with esophageal adenocarcinoma. Sci Rep. 2018;8:7265 pubmed 出版商
Dungrawala H, Bhat K, Le Meur R, Chazin W, Ding X, Sharan S, et al. RADX Promotes Genome Stability and Modulates Chemosensitivity by Regulating RAD51 at Replication Forks. Mol Cell. 2017;67:374-386.e5 pubmed 出版商
Di Marco S, Hasanova Z, Kanagaraj R, Chappidi N, Altmannova V, Menon S, et al. RECQ5 Helicase Cooperates with MUS81 Endonuclease in Processing Stalled Replication Forks at Common Fragile Sites during Mitosis. Mol Cell. 2017;66:658-671.e8 pubmed 出版商
Wyatt H, Laister R, Martin S, Arrowsmith C, West S. The SMX DNA Repair Tri-nuclease. Mol Cell. 2017;65:848-860.e11 pubmed 出版商
Minocherhomji S, Ying S, Bjerregaard V, Bursomanno S, Aleliunaite A, Wu W, et al. Replication stress activates DNA repair synthesis in mitosis. Nature. 2015;528:286-90 pubmed 出版商
Pepe A, West S. Substrate specificity of the MUS81-EME2 structure selective endonuclease. Nucleic Acids Res. 2014;42:3833-45 pubmed 出版商
Duquette M, Zhu Q, Taylor E, Tsay A, Shi L, Berns M, et al. CtIP is required to initiate replication-dependent interstrand crosslink repair. PLoS Genet. 2012;8:e1003050 pubmed 出版商
Kim Y, Lach F, Desetty R, Hanenberg H, Auerbach A, Smogorzewska A. Mutations of the SLX4 gene in Fanconi anemia. Nat Genet. 2011;43:142-6 pubmed 出版商
产品信息
目录号 :
ab14387
ItemName :
抗Mus81抗体[MTA30 2G10/3]
类别 :
抗体
宿主 :
小鼠
克隆性 :
单克隆
共轭标签 :
未共轭
克隆名称 :
MTA30 2G10/3
规格 :
100微克
物种摘要 :
Hu
应用摘要 :
Flow Cyt, ICC/IF, IP, WB
公司信息
艾博抗(上海)贸易有限公司
上海市浦东新区伽利略路338号5幢4层5401室
cn.technical@abcam.com
http://www.abcam.cn
400-628-6880 86-21-5110 5938
公司总部: 英国
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