产品简要
公司名称 :
艾博抗(上海)贸易有限公司
其他品牌 :
Epitomics, Ascent Scientific, MitoSciences
产品类型 :
抗体
产品名称 :
抗细胞周期蛋白D1抗体[SP4]
目录 :
ab16663
规格 :
1毫升, 100微升, 500微升
克隆性 :
单克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
克隆名称 :
SP4
反应物种 :
人类, 小鼠
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫组化-石蜡切片, 免疫组化-冰冻切片, 免疫组化-自由浮动切片
文章摘录数: 74
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 小鼠; 1:50; 图 5f
Zou J, Pei X, Xing D, Wu X, Chen S. LINC00261 elevation inhibits angiogenesis and cell cycle progression of pancreatic cancer cells by upregulating SCP2 via targeting FOXP3. J Cell Mol Med. 2021;25:9826-9836 pubmed 出版商
  • 免疫印迹; 人类; 1:200; 图 4c
Huang J, Xiao R, Wang X, Khadka B, Fang Z, Yu M, et al. MicroRNA‑93 knockdown inhibits acute myeloid leukemia cell growth via inactivating the PI3K/AKT pathway by upregulating DAB2. Int J Oncol. 2021;59: pubmed 出版商
  • 免疫印迹; 人类; 图 1j
Mygland L, Brinch S, Strand M, Olsen P, Aizenshtadt A, Lund K, et al. Identification of response signatures for tankyrase inhibitor treatment in tumor cell lines. iScience. 2021;24:102807 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 3h
Nishad R, Mukhi D, Singh A, Motrapu M, Chintala K, Tammineni P, et al. Growth hormone induces mitotic catastrophe of glomerular podocytes and contributes to proteinuria. Cell Death Dis. 2021;12:342 pubmed 出版商
  • 免疫组化; 小鼠; 1:400
Liu X, Zhang H, Zhou P, Yu Y, Zhang H, Chen L, et al. CREB1 acts via the miR‑922/ARID2 axis to enhance malignant behavior of liver cancer cells. Oncol Rep. 2021;45: pubmed 出版商
  • 免疫印迹; 人类; 1:200; 图 2b
Liu W, Li J, Zhang D, Chen B, Wang X, Zhang X, et al. Trefoil factor 1 and gastrokine 2 inhibit Helicobacter pylori-induced proliferation and inflammation in gastric cardia and distal carcinogenesis. Oncol Lett. 2020;20:318 pubmed 出版商
  • 免疫印迹; 人类; 图 2c
Gu Y, Zhu Z, Pei H, Xu D, Jiang Y, Zhang L, et al. Long non-coding RNA NNT-AS1 promotes cholangiocarcinoma cells proliferation and epithelial-to-mesenchymal transition through down-regulating miR-203. Aging (Albany NY). 2020;12:2333-2346 pubmed 出版商
  • 免疫组化; 小鼠; 1:300; 图 1m
Wang L, Xie J, Zhang H, Tsang L, Tsang S, Braune E, et al. Notch signalling regulates epibranchial placode patterning and segregation. Development. 2020;147: pubmed 出版商
  • 免疫印迹; 人类; 1:100; 图 6c, 6d
Liao S, Chen H, Liu M, Gan L, Li C, Zhang W, et al. Aquaporin 9 inhibits growth and metastasis of hepatocellular carcinoma cells via Wnt/β-catenin pathway. Aging (Albany NY). 2020;12:1527-1544 pubmed 出版商
  • 免疫印迹; 人类; 1:150; 图 6b, 6d
Jiang K, Zhi X, Ma Y, Zhou L. Long non-coding RNA TOB1-AS1 modulates cell proliferation, apoptosis, migration and invasion through miR-23a/NEU1 axis via Wnt/b-catenin pathway in gastric cancer. Eur Rev Med Pharmacol Sci. 2019;23:9890-9899 pubmed 出版商
  • 免疫印迹; 人类; 图 2j
Liu J, Yao L, Zhang M, Jiang J, Yang M, Wang Y. Downregulation of LncRNA-XIST inhibited development of non-small cell lung cancer by activating miR-335/SOD2/ROS signal pathway mediated pyroptotic cell death. Aging (Albany NY). 2019;11:7830-7846 pubmed 出版商
  • 免疫印迹; 人类; 图 4a
Piao L, Yang Z, Feng Y, Zhang C, Cui C, Xuan Y. LETM1 is a potential biomarker of prognosis in lung non-small cell carcinoma. BMC Cancer. 2019;19:898 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 6a
Liu B, Zhang J, Yang D. miR-96-5p promotes the proliferation and migration of ovarian cancer cells by suppressing Caveolae1. J Ovarian Res. 2019;12:57 pubmed 出版商
  • 免疫印迹; 人类; 1:200; 图 4e
Harrod A, Fulton J, Nguyen V, Periyasamy M, Ramos Garcia L, Lai C, et al. Genomic modelling of the ESR1 Y537S mutation for evaluating function and new therapeutic approaches for metastatic breast cancer. Oncogene. 2017;36:2286-2296 pubmed 出版商
  • 免疫印迹; 人类; 1:200; 图 3a
Morris J, Moseley V, Cabang A, Coleman K, Wei W, Garrett Mayer E, et al. Reduction in promotor methylation utilizing EGCG (epigallocatechin-3-gallate) restores RXR? expression in human colon cancer cells. Oncotarget. 2016;7:35313-26 pubmed 出版商
  • 免疫印迹; 人类; 图 5a
Hong J, Lee J, Chung I. Telomerase activates transcription of cyclin D1 gene through an interaction with NOL1. J Cell Sci. 2016;129:1566-79 pubmed 出版商
  • 免疫组化; 小鼠; 1:100; 图 1
Lanza D, Dawson E, Rao P, Heaney J. Misexpression of cyclin D1 in embryonic germ cells promotes testicular teratoma initiation. Cell Cycle. 2016;15:919-30 pubmed 出版商
  • 免疫印迹; 人类; 图 3
Wu L, Guo L, Liang Y, Liu X, Jiang L, Wang L. Curcumin suppresses stem-like traits of lung cancer cells via inhibiting the JAK2/STAT3 signaling pathway. Oncol Rep. 2015;34:3311-7 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 5b
Zhuo W, Ge W, Meng G, Jia S, Zhou X, Liu J. MicroRNA‑20a promotes the proliferation and cell cycle of human osteosarcoma cells by suppressing early growth response 2 expression. Mol Med Rep. 2015;12:4989-94 pubmed 出版商
  • 免疫印迹; 人类; 图 s1c
Yan K, Li L, Wang X, Hong R, Zhang Y, Yang H, et al. The deubiquitinating enzyme complex BRISC is required for proper mitotic spindle assembly in mammalian cells. J Cell Biol. 2015;210:209-24 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 s2
Wilson C, Jurk D, Fullard N, Banks P, Page A, Luli S, et al. NFκB1 is a suppressor of neutrophil-driven hepatocellular carcinoma. Nat Commun. 2015;6:6818 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1:400; 图 3f
Yuan G, Yang G, Zheng Y, Zhu X, Chen Z, Zhang Z, et al. The non-canonical BMP and Wnt/β-catenin signaling pathways orchestrate early tooth development. Development. 2015;142:128-39 pubmed 出版商
  • 免疫组化-自由浮动切片; 小鼠; 1:250
Bhaskar K, Maphis N, Xu G, Varvel N, Kokiko Cochran O, Weick J, et al. Microglial derived tumor necrosis factor-? drives Alzheimer's disease-related neuronal cell cycle events. Neurobiol Dis. 2014;62:273-85 pubmed 出版商
Samson J, Derlipanska M, Zaheed O, Dean K. Molecular and cellular characterization of two patient-derived ductal carcinoma in situ (DCIS) cell lines, ETCC-006 and ETCC-010. BMC Cancer. 2021;21:790 pubmed 出版商
Zhang Y, Ding L, Ni Q, Tao R, Qin J. Transcription factor PAX4 facilitates gastric cancer progression through interacting with miR-27b-3p/Grb2 axis. Aging (Albany NY). 2021;13:16786-16803 pubmed 出版商
Xie M, Wu Z, Ying S, Liu L, Zhao C, Yao C, et al. Sublytic C5b-9 induces glomerular mesangial cell proliferation via ERK1/2-dependent SOX9 phosphorylation and acetylation by enhancing Cyclin D1 in rat Thy-1 nephritis. Exp Mol Med. 2021;53:572-590 pubmed 出版商
Yin X, Zhang Y, Wen Y, Yang Y, Chen H. Celecoxib alleviates zinc deficiency-promoted colon tumorigenesis through suppressing inflammation. Aging (Albany NY). 2021;13:8320-8334 pubmed 出版商
Cong J, Gong J, Yang C, Xia Z, Zhang H. MiR-200c/FUT4 axis prevents the proliferation of colon cancer cells by downregulating the Wnt/β-catenin pathway. BMC Cancer. 2021;21:2 pubmed 出版商
Diao W, Guo Q, Zhu C, Song Y, Feng H, Cao Y, et al. USP18 promotes cell proliferation and suppressed apoptosis in cervical cancer cells via activating AKT signaling pathway. BMC Cancer. 2020;20:741 pubmed 出版商
Jiang T, Chen Z, Chen Z, Tan D. SULF2 promotes tumorigenesis and inhibits apoptosis of cervical cancer cells through the ERK/AKT signaling pathway. Braz J Med Biol Res. 2020;53:e8901 pubmed 出版商
Hao L, Pang K, Pang H, Zhang J, Zhang Z, He H, et al. Knockdown of P3H4 inhibits proliferation and invasion of bladder cancer. Aging (Albany NY). 2020;12:2156-2168 pubmed 出版商
Wang H, Ma N, Li W, Wang Z. MicroRNA-96-5p promotes proliferation, invasion and EMT of oral carcinoma cells by directly targeting FOXF2. Biol Open. 2020;9: pubmed 出版商
Wang W, Guo P, Chen M, Chen D, Cheng Y, He L. FOXM1/LINC00152 feedback loop regulates proliferation and apoptosis in rheumatoid arthritis fibroblast-like synoviocytes via Wnt/β-catenin signaling pathway. Biosci Rep. 2020;40: pubmed 出版商
Yang J, Shi S, Xu W, Qiu Y, Zheng J, Yu K, et al. Screening, identification and validation of CCND1 and PECAM1/CD31 for predicting prognosis in renal cell carcinoma patients. Aging (Albany NY). 2019;11:12057-12079 pubmed 出版商
Liao D, Chen W, Tan C, Wong J, Chan P, Tan L, et al. Upregulation of Yy1 Suppresses Dilated Cardiomyopathy caused by Ttn insufficiency. Sci Rep. 2019;9:16330 pubmed 出版商
Tan C, Wong J, Chan P, Tan H, Liao D, Chen W, et al. Yin Yang 1 Suppresses Dilated Cardiomyopathy and Cardiac Fibrosis Through Regulation of Bmp7 and Ctgf. Circ Res. 2019;125:834-846 pubmed 出版商
Deng H, Huang C, Wang Y, Jiang H, Peng S, Zhao X. LINC00511 promotes the malignant phenotype of clear cell renal cell carcinoma by sponging microRNA-625 and thereby increasing cyclin D1 expression. Aging (Albany NY). 2019;11:5975-5991 pubmed 出版商
Li S, Lu D, Tang J, Min J, Hu M, Li Y, et al. Electrical Stimulation Activates Fibroblasts through the Elevation of Intracellular Free Ca2+: Potential Mechanism of Pelvic Electrical Stimulation Therapy. Biomed Res Int. 2019;2019:7387803 pubmed 出版商
Du J, Yang S, Liu J, Zhang K, Leng J. Silence of LncRNA GAS5 Protects Cardiomyocytes H9c2 against Hypoxic Injury via Sponging miR-142-5p. Mol Cells. 2019;42:397-405 pubmed 出版商
Yu X, Pang L, Yang T, Liu P. lncRNA LINC01296 regulates the proliferation, metastasis and cell cycle of osteosarcoma through cyclin D1. Oncol Rep. 2018;40:2507-2514 pubmed 出版商
Gu W, Mochizuki K, Otsuka K, Hamada R, Takehara A, Matsui Y. Dnd1-mediated epigenetic control of teratoma formation in mouse. Biol Open. 2018;7: pubmed 出版商
Huang B, Li X, Tu X, Zhao W, Zhu D, Feng Y, et al. OTX1 regulates cell cycle progression of neural progenitors in the developing cerebral cortex. J Biol Chem. 2018;293:2137-2148 pubmed 出版商
Mack J, Mosqueiro T, Archer B, Jones W, Sunshine H, Faas G, et al. NOTCH1 is a mechanosensor in adult arteries. Nat Commun. 2017;8:1620 pubmed 出版商
Read M, Fong J, Modasia B, Fletcher A, Imruetaicharoenchoke W, Thompson R, et al. Elevated PTTG and PBF predicts poor patient outcome and modulates DNA damage response genes in thyroid cancer. Oncogene. 2017;36:5296-5308 pubmed 出版商
Wen D, Peng Y, Lin F, Singh R, Mahato R. Micellar Delivery of miR-34a Modulator Rubone and Paclitaxel in Resistant Prostate Cancer. Cancer Res. 2017;77:3244-3254 pubmed 出版商
Mulligan W, Wegner K, Keil K, Mehta V, Taketo M, Vezina C. Beta-catenin and estrogen signaling collaborate to drive cyclin D1 expression in developing mouse prostate. Differentiation. 2017;93:66-71 pubmed 出版商
Wu J, Chen Z, Liu Q, Zeng W, Wu X, Lin B. Silencing of Kv1.5 Gene Inhibits Proliferation and Induces Apoptosis of Osteosarcoma Cells. Int J Mol Sci. 2015;16:26914-26 pubmed 出版商
Wang Y, Zhou X, Shan B, Han J, Wang F, Fan X, et al. Downregulation of microRNA‑33a promotes cyclin‑dependent kinase 6, cyclin D1 and PIM1 expression and gastric cancer cell proliferation. Mol Med Rep. 2015;12:6491-500 pubmed 出版商
Marthandan S, Priebe S, Hemmerich P, Klement K, Diekmann S. Long-term quiescent fibroblast cells transit into senescence. PLoS ONE. 2014;9:e115597 pubmed 出版商
Hendaoui I, Tucker R, Zingg D, Bichet S, Schittny J, Chiquet Ehrismann R. Tenascin-C is required for normal Wnt/β-catenin signaling in the whisker follicle stem cell niche. Matrix Biol. 2014;40:46-53 pubmed 出版商
Lin F, Lee Y, Goan Y, Tsai C, Yao Y, Cheng H, et al. Pin1 positively affects tumorigenesis of esophageal squamous cell carcinoma and correlates with poor survival of patients. J Biomed Sci. 2014;21:75 pubmed 出版商
Zheng L, Zhu K, Jiao H, Zhao Z, Zhang L, Liu M, et al. PTHrP expression in human MDA-MB-231 breast cancer cells is critical for tumor growth and survival and osteoblast inhibition. Int J Biol Sci. 2013;9:830-41 pubmed 出版商
Vasilopoulou E, Loubiere L, Heuer H, Trajkovic Arsic M, Darras V, Visser T, et al. Monocarboxylate transporter 8 modulates the viability and invasive capacity of human placental cells and fetoplacental growth in mice. PLoS ONE. 2013;8:e65402 pubmed 出版商
Ikeda Y, Oda K, Hiraike Wada O, Koso T, Miyasaka A, Kashiyama T, et al. Cyclin D1 harboring the T286I mutation promotes oncogenic activation in endometrial cancer. Oncol Rep. 2013;30:584-8 pubmed 出版商
Upadhya D, Ogata M, Reneker L. MAPK1 is required for establishing the pattern of cell proliferation and for cell survival during lens development. Development. 2013;140:1573-82 pubmed 出版商
Fristrup N, Birkenkamp Demtroder K, Reinert T, Sanchez Carbayo M, Segersten U, Malmstrom P, et al. Multicenter validation of cyclin D1, MCM7, TRIM29, and UBE2C as prognostic protein markers in non-muscle-invasive bladder cancer. Am J Pathol. 2013;182:339-49 pubmed 出版商
Booher K, Lin D, Borrego S, Kaiser P. Downregulation of Cdc6 and pre-replication complexes in response to methionine stress in breast cancer cells. Cell Cycle. 2012;11:4414-23 pubmed 出版商
Toledano Y, Zonis S, Ren S, Wawrowsky K, Chesnokova V, Melmed S. Estradiol partially recapitulates murine pituitary cell cycle response to pregnancy. Endocrinology. 2012;153:5011-22 pubmed
McIver S, Stanger S, Santarelli D, Roman S, Nixon B, McLaughlin E. A unique combination of male germ cell miRNAs coordinates gonocyte differentiation. PLoS ONE. 2012;7:e35553 pubmed 出版商
Heaney J, Anderson E, Michelson M, Zechel J, Conrad P, Page D, et al. Germ cell pluripotency, premature differentiation and susceptibility to testicular teratomas in mice. Development. 2012;139:1577-86 pubmed 出版商
Patel V, Feng L, Lee D, Massenburg D, Pattabiraman G, Antoni A, et al. Recognition-dependent signaling events in response to apoptotic targets inhibit epithelial cell viability by multiple mechanisms: implications for non-immune tissue homeostasis. J Biol Chem. 2012;287:13761-77 pubmed 出版商
He Z, Campolmi N, Ha Thi B, Dumollard J, Peoc h M, Garraud O, et al. Optimization of immunolocalization of cell cycle proteins in human corneal endothelial cells. Mol Vis. 2011;17:3494-511 pubmed
Terradas M, Martin M, Hernández L, Tusell L, Genesca A. Nuclear envelope defects impede a proper response to micronuclear DNA lesions. Mutat Res. 2012;729:35-40 pubmed 出版商
Read M, Lewy G, Fong J, Sharma N, Seed R, Smith V, et al. Proto-oncogene PBF/PTTG1IP regulates thyroid cell growth and represses radioiodide treatment. Cancer Res. 2011;71:6153-64 pubmed 出版商
Galatioto J, Mascareno E, Siddiqui M. CLP-1 associates with MyoD and HDAC to restore skeletal muscle cell regeneration. J Cell Sci. 2010;123:3789-95 pubmed 出版商
Almeida M, Muchow M, Boikos S, Bauer A, Griffin K, Tsang K, et al. Mouse Prkar1a haploinsufficiency leads to an increase in tumors in the Trp53+/- or Rb1+/- backgrounds and chemically induced skin papillomas by dysregulation of the cell cycle and Wnt signaling. Hum Mol Genet. 2010;19:1387-98 pubmed 出版商
Genander M, Halford M, Xu N, Eriksson M, Yu Z, Qiu Z, et al. Dissociation of EphB2 signaling pathways mediating progenitor cell proliferation and tumor suppression. Cell. 2009;139:679-92 pubmed 出版商
Ivanova M, Mazhawidza W, Dougherty S, Klinge C. Sex differences in estrogen receptor subcellular location and activity in lung adenocarcinoma cells. Am J Respir Cell Mol Biol. 2010;42:320-30 pubmed 出版商
Ogino S, Nosho K, Irahara N, Kure S, Shima K, Baba Y, et al. A cohort study of cyclin D1 expression and prognosis in 602 colon cancer cases. Clin Cancer Res. 2009;15:4431-8 pubmed 出版商
Nosho K, Kawasaki T, Chan A, Ohnishi M, Suemoto Y, Kirkner G, et al. Cyclin D1 is frequently overexpressed in microsatellite unstable colorectal cancer, independent of CpG island methylator phenotype. Histopathology. 2008;53:588-98 pubmed 出版商
Fleming I, Hogben M, Frame S, McClue S, Green S. Synergistic inhibition of ErbB signaling by combined treatment with seliciclib and ErbB-targeting agents. Clin Cancer Res. 2008;14:4326-35 pubmed 出版商
Dance Barnes S, Kock N, Floyd H, Moore J, Mosley L, D Agostino R, et al. Effects of mutant human Ki-ras(G12C) gene dosage on murine lung tumorigenesis and signaling to its downstream effectors. Toxicol Appl Pharmacol. 2008;231:77-84 pubmed 出版商
Gibcus J, Mastik M, Menkema L, de Bock G, Kluin P, Schuuring E, et al. Cortactin expression predicts poor survival in laryngeal carcinoma. Br J Cancer. 2008;98:950-5 pubmed 出版商
Henderson J, Al Waheeb S, Weins A, Dandapani S, Pollak M. Mice with altered alpha-actinin-4 expression have distinct morphologic patterns of glomerular disease. Kidney Int. 2008;73:741-50 pubmed 出版商
产品信息
目录号 :
ab16663
ItemName :
抗细胞周期蛋白D1抗体[SP4]
类别 :
抗体
宿主 :
克隆性 :
单克隆
共轭标签 :
未共轭
克隆名称 :
SP4
规格 :
1毫升, 100微升, 500微升
物种摘要 :
Hu, Ms
应用摘要 :
免疫细胞化学, 免疫细胞化学/IF, 免疫组化-P, 免疫组化-P, 免疫印迹
公司信息
艾博抗(上海)贸易有限公司
上海市浦东新区伽利略路338号5幢4层5401室
cn.technical@abcam.com
http://www.abcam.cn
400-628-6880 86-21-5110 5938
公司总部: 英国
Abcam是全球知名的生命科学研究领域产品提供商,产品涵盖一抗、二抗、蛋白、多肽及ELISA kit。