产品简要
公司名称 :
艾博抗(上海)贸易有限公司
其他品牌 :
Epitomics, Ascent Scientific, MitoSciences
产品类型 :
抗体
产品名称 :
抗肿瘤坏死因子甲抗体[52B83]
目录 :
ab1793
规格 :
50微克
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
52B83
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学, 流式细胞仪, 免疫组化-石蜡切片, 免疫组化-冰冻切片, 免疫组化-自由浮动切片, 免疫印迹基因敲除验证
文章摘录数: 73
出版应用/物种/样本/稀释参考文献
  • 免疫组化; 大鼠; 图 5b
  • 免疫印迹; 大鼠; 1:1000; 图 1b
Yadav A, Huang T, Chen S, Ramasamy T, Hsueh Y, Lin S, et al. Sodium phenylbutyrate inhibits Schwann cell inflammation via HDAC and NFκB to promote axonal regeneration and remyelination. J Neuroinflammation. 2021;18:238 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:150; 图 5d
Tang Z, Xiong D, Song J, Ye M, Liu J, Wang Z, et al. Antitumor Drug Combretastatin-A4 Phosphate Aggravates the Symptoms of Dextran Sulfate Sodium-Induced Ulcerative Colitis in Mice. Front Pharmacol. 2020;11:339 pubmed 出版商
  • 免疫印迹基因敲除验证; 小鼠; 图 s7b
  • 免疫印迹; 小鼠; 图 1a, 1c
Fu X, Peng J, Wang A, Luo Z. Tumor necrosis factor alpha mediates neuromuscular synapse elimination. Cell Discov. 2020;6:9 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 图 6a
Tezera L, Bielecka M, Ogongo P, Walker N, Ellis M, Garay Baquero D, et al. Anti-PD-1 immunotherapy leads to tuberculosis reactivation via dysregulation of TNF-α. elife. 2020;9: pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1:200; 图 8a
  • 免疫印迹; 小鼠; 图 8c
Tang X, Yan K, Wang Y, Wang Y, Chen H, Xu J, et al. Activation of PPAR-β/δ Attenuates Brain Injury by Suppressing Inflammation and Apoptosis in a Collagenase-Induced Intracerebral Hemorrhage Mouse Model. Neurochem Res. 2020;45:837-850 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:500; 图 6a
Chen K, Gu H, Zhu L, Feng D. A New Model of Repetitive Traumatic Brain Injury in Mice. Front Neurosci. 2019;13:1417 pubmed 出版商
  • 免疫组化; 小鼠; 图 3c
Portillo J, Lopez Corcino Y, Miao Y, Tang J, Sheibani N, Kern T, et al. CD40 in Retinal Müller Cells Induces P2X7-Dependent Cytokine Expression in Macrophages/Microglia in Diabetic Mice and Development of Early Experimental Diabetic Retinopathy. Diabetes. 2017;66:483-493 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:500; 图 5
Dai Y, Miao Y, Wu W, Li Y, D Errico F, Su W, et al. Ablation of Liver X receptors ? and ? leads to spontaneous peripheral squamous cell lung cancer in mice. Proc Natl Acad Sci U S A. 2016;113:7614-9 pubmed 出版商
  • 流式细胞仪; 人类; 图 5a
Perotti V, Baldassari P, Molla A, Vegetti C, Bersani I, Maurichi A, et al. NFATc2 is an intrinsic regulator of melanoma dedifferentiation. Oncogene. 2016;35:2862-72 pubmed 出版商
  • 免疫印迹; 大鼠; 1:1000; 图 2
Lin Y, Chen L, Li W, Fang J. Role of high-mobility group box-1 in myocardial ischemia/reperfusion injury and the effect of ethyl pyruvate. Exp Ther Med. 2015;9:1537-1541 pubmed
  • 免疫组化-自由浮动切片; 人类; 1:10
López González I, Schlüter A, Aso E, Garcia Esparcia P, Ansoleaga B, Llorens F, et al. Neuroinflammatory signals in Alzheimer disease and APP/PS1 transgenic mice: correlations with plaques, tangles, and oligomeric species. J Neuropathol Exp Neurol. 2015;74:319-44 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:100; 图 2
Zhou L, Park S, Xu L, Xia X, Ye J, Su L, et al. Insulin resistance and white adipose tissue inflammation are uncoupled in energetically challenged Fsp27-deficient mice. Nat Commun. 2015;6:5949 pubmed 出版商
  • 免疫组化; 大鼠; 1:150; 图 3a
He D, Kou X, Luo Q, Yang R, Liu D, Wang X, et al. Enhanced M1/M2 macrophage ratio promotes orthodontic root resorption. J Dent Res. 2015;94:129-39 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000
Domitrovic R, Cvijanovic O, Susnić V, Katalinić N. Renoprotective mechanisms of chlorogenic acid in cisplatin-induced kidney injury. Toxicology. 2014;324:98-107 pubmed 出版商
  • 免疫组化; 人类; 1:20
Hagel C, Krasemann S, Löffler J, Puschel K, Magnus T, Glatzel M. Upregulation of Shiga toxin receptor CD77/Gb3 and interleukin-1? expression in the brain of EHEC patients with hemolytic uremic syndrome and neurologic symptoms. Brain Pathol. 2015;25:146-56 pubmed 出版商
  • 免疫组化; 人类; 1:100; 图 5c
Chen D, Mao M, Bellussi L, Passali D, Chen L. Increase of high mobility group box chromosomal protein 1 in eosinophilic chronic rhinosinusitis with nasal polyps. Int Forum Allergy Rhinol. 2014;4:453-62 pubmed 出版商
  • 免疫细胞化学; 小鼠; 2 ug/ml
  • 免疫印迹; 小鼠; 1:1000
Bhaskar K, Maphis N, Xu G, Varvel N, Kokiko Cochran O, Weick J, et al. Microglial derived tumor necrosis factor-? drives Alzheimer's disease-related neuronal cell cycle events. Neurobiol Dis. 2014;62:273-85 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000
Domitrovic R, Cvijanovic O, Pernjak Pugel E, Skoda M, Mikelić L, Crncevic Orlic Z. Berberine exerts nephroprotective effect against cisplatin-induced kidney damage through inhibition of oxidative/nitrosative stress, inflammation, autophagy and apoptosis. Food Chem Toxicol. 2013;62:397-406 pubmed 出版商
  • 免疫组化-冰冻切片; 大鼠
  • 免疫细胞化学; 大鼠
Ishikawa H, Tajiri N, Vasconcellos J, Kaneko Y, Mimura O, Dezawa M, et al. Ischemic stroke brain sends indirect cell death signals to the heart. Stroke. 2013;44:3175-82 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000
Domitrovic R, Cvijanovic O, Pugel E, Zagorac G, Mahmutefendić H, Skoda M. Luteolin ameliorates cisplatin-induced nephrotoxicity in mice through inhibition of platinum accumulation, inflammation and apoptosis in the kidney. Toxicology. 2013;310:115-23 pubmed 出版商
Orso G, Solovyev M, Facchiano S, Tyrikova E, Sateriale D, Kashinskaya E, et al. Chestnut Shell Tannins: Effects on Intestinal Inflammation and Dysbiosis in Zebrafish. Animals (Basel). 2021;11: pubmed 出版商
Huang S, Mo C, Zeng T, Lai Y, Zhou C, Xie S, et al. Lupeol ameliorates LPS/D-GalN induced acute hepatic damage by suppressing inflammation and oxidative stress through TGFβ1-Nrf2 signal pathway. Aging (Albany NY). 2021;13:6592-6605 pubmed 出版商
Imperatore R, Tunisi L, Mavaro I, D angelo L, Attanasio C, Safari O, et al. Immunohistochemical Analysis of Intestinal and Central Nervous System Morphology in an Obese Animal Model (Danio rerio) Treated with 3,5-T2: A Possible Farm Management Practice?. Animals (Basel). 2020;10: pubmed 出版商
Ibrahim S, Harris Kawano A, Haider I, Mirmira R, Sims E, Anderson R. A novel Cre-enabled tetracycline-inducible transgenic system for tissue-specific cytokine expression in the zebrafish: CETI-PIC3. Dis Model Mech. 2020;13: pubmed 出版商
Zhang R, Wang T, Yin Q, Zhang J, Li L, Guo R, et al. FcgRIII Deficiency and FcgRIIb Defeciency Promote Renal Injury in Diabetic Mice. Biomed Res Int. 2019;2019:3514574 pubmed 出版商
Ottaiano A, Scala S, Normanno N, Napolitano M, Capozzi M, Rachiglio A, et al. Cetuximab, irinotecan and fluorouracile in fiRst-line treatment of immunologically-selected advanced colorectal cancer patients: the CIFRA study protocol. BMC Cancer. 2019;19:899 pubmed 出版商
Ativie F, Komorowska J, Beins E, Albayram O, Zimmer T, Zimmer A, et al. Cannabinoid 1 Receptor Signaling on Hippocampal GABAergic Neurons Influences Microglial Activity. Front Mol Neurosci. 2018;11:295 pubmed 出版商
Farsky P, Hirata M, Arnoni R, Almeida A, Issa M, Lima P, et al. Persistent Inflammatory Activity in Blood Cells and Artery Tissue from Patients with Previous Bare Metal Stent. Arq Bras Cardiol. 2018;111:134-141 pubmed 出版商
Liu G, Zhang W. Long non-coding RNA HOTAIR promotes UVB-induced apoptosis and inflammatory injury by up-regulation of PKR in keratinocytes. Braz J Med Biol Res. 2018;51:e6896 pubmed 出版商
Wu N, Liao F, Cheng H, Sung S, Yang Y, Wang J. Intravenous superoxide dismutase as a protective agent to prevent impairment of lung function induced by high tidal volume ventilation. BMC Pulm Med. 2017;17:105 pubmed 出版商
Andrés Benito P, Moreno J, Aso E, Povedano M, Ferrer I. Amyotrophic lateral sclerosis, gene deregulation in the anterior horn of the spinal cord and frontal cortex area 8: implications in frontotemporal lobar degeneration. Aging (Albany NY). 2017;9:823-851 pubmed 出版商
Liu M, Verma N, Peng X, Srodulski S, Morris A, Chow M, et al. Hyperamylinemia Increases IL-1β Synthesis in the Heart via Peroxidative Sarcolemmal Injury. Diabetes. 2016;65:2772-83 pubmed 出版商
Akdogan R, Kalkan Y, Tumkaya L, Rakıcı H, Akdogan E. The Effects of Infliximab on Laminin, NF?B, and Anti-TNF Expression through Its Effect on Ischemic Liver Tissue. Gastroenterol Res Pract. 2016;2016:1738430 pubmed 出版商
Zhu Z, Cai W, Wang T, Ye H, Zhu Y, Chi L, et al. bFGF-Regulating MAPKs Are Involved in High Glucose-Mediated ROS Production and Delay of Vascular Endothelial Cell Migration. PLoS ONE. 2015;10:e0144495 pubmed 出版商
Bai Y, Hu L, Yu D, Peng S, Liu X, Zhang M, et al. Evolution of Coronary Flow in an Experimental Slow Flow Model in Swines: Angiographic and Pathological Insights. Biomed Res Int. 2015;2015:623986 pubmed 出版商
Zhang Z, Yang P, Yao P, Dai D, Yu Y, Zhou Y, et al. Identification of transcription factors and gene clusters in rabbit smooth muscle cells during high flow-induced vascular remodeling via microarray. Gene. 2016;575:407-414 pubmed 出版商
Berjaoui S, Povedano M, Garcia Esparcia P, Carmona M, Aso E, Ferrer I. Complex Inflammation mRNA-Related Response in ALS Is Region Dependent. Neural Plast. 2015;2015:573784 pubmed 出版商
Naqvi A, Fordham J, Nares S. miR-24, miR-30b, and miR-142-3p regulate phagocytosis in myeloid inflammatory cells. J Immunol. 2015;194:1916-27 pubmed 出版商
Rana T, Shinde V, Starr C, Kruglov A, Boitet E, Kotla P, et al. An activated unfolded protein response promotes retinal degeneration and triggers an inflammatory response in the mouse retina. Cell Death Dis. 2014;5:e1578 pubmed 出版商
Llorens F, Lopez Gonzalez I, Thune K, Carmona M, Zafar S, Andreoletti O, et al. Subtype and regional-specific neuroinflammation in sporadic creutzfeldt-jakob disease. Front Aging Neurosci. 2014;6:198 pubmed 出版商
Mendes L, Scarano W, Rochel Maia S, Fioruci Fontaneli B, Chuffa L, Martinez F. Testosterone therapy differently regulates the anti- and pro-inflammatory cytokines in the plasma and prostate of rats submitted to chronic ethanol consumption (UChB). Am J Reprod Immunol. 2014;72:317-25 pubmed 出版商
Jiménez A, Rodríguez Pérez L, Domínguez Pinos M, Gómez Roldán M, García Bonilla M, Ho Plagaro A, et al. Increased levels of tumour necrosis factor alpha (TNF?) but not transforming growth factor-beta 1 (TGF?1) are associated with the severity of congenital hydrocephalus in the hyh mouse. Neuropathol Appl Neurobiol. 2014;40:911-32 pubmed 出版商
Yuan S, Shi Y, Chen J, Zhou X, Li G, Gelman B, et al. Gp120 in the pathogenesis of human immunodeficiency virus-associated pain. Ann Neurol. 2014;75:837-50 pubmed 出版商
Cong W, Zhao T, Zhu Z, Huang B, Ma W, Wang Y, et al. Metallothionein prevents cardiac pathological changes in diabetes by modulating nitration and inactivation of cardiac ATP synthase. J Nutr Biochem. 2014;25:463-74 pubmed 出版商
Bhattacharjee J, Kumar J, Arindkar S, Das B, Pramod U, Juyal R, et al. Role of immunodeficient animal models in the development of fructose induced NAFLD. J Nutr Biochem. 2014;25:219-26 pubmed 出版商
Inoue H, Arai Y, Kishida T, Shin Ya M, Terauchi R, Nakagawa S, et al. Sonoporation-mediated transduction of siRNA ameliorated experimental arthritis using 3 MHz pulsed ultrasound. Ultrasonics. 2014;54:874-81 pubmed 出版商
Lu Z, Lv K, Zhang J, Dai C, Liu B, Ma X, et al. Establishment of a green fluorescent protein tracing murine model focused on the functions of host components in necrosis repair and the niche of subcutaneously implanted glioma. Oncol Rep. 2014;31:657-64 pubmed 出版商
Liesz A, Zhou W, Na S, Hämmerling G, Garbi N, Karcher S, et al. Boosting regulatory T cells limits neuroinflammation in permanent cortical stroke. J Neurosci. 2013;33:17350-62 pubmed 出版商
Hu S, Mei L, Chen J, Huang Z, Wu H. Effects of salicylate on the inflammatory genes expression and synaptic ultrastructure in the cochlear nucleus of rats. Inflammation. 2014;37:365-73 pubmed 出版商
Jang J, Lee J, Jeon Y, Kim C. Exosome derived from epigallocatechin gallate treated breast cancer cells suppresses tumor growth by inhibiting tumor-associated macrophage infiltration and M2 polarization. BMC Cancer. 2013;13:421 pubmed 出版商
Tian X, Hua F, Sandhu H, Chao D, Balboni G, Salvadori S, et al. Effect of ?-opioid receptor activation on BDNF-TrkB vs. TNF-? in the mouse cortex exposed to prolonged hypoxia. Int J Mol Sci. 2013;14:15959-76 pubmed 出版商
Domitrovic R, Jakovac H, Marchesi V, Blazeković B. Resolution of liver fibrosis by isoquinoline alkaloid berberine in CCl?-intoxicated mice is mediated by suppression of oxidative stress and upregulation of MMP-2 expression. J Med Food. 2013;16:518-28 pubmed 出版商
Cho A, Kim J, Lee D, Lee J, Jung U, Bak E, et al. The effect of orally administered epigallocatechin-3-gallate on ligature-induced periodontitis in rats. J Periodontal Res. 2013;48:781-9 pubmed 出版商
Shin S, Cho Y, Jun H, Park H, Hong H, Kwon T. Transglutaminase type 2 in human abdominal aortic aneurysm is a potential factor in the stabilization of extracellular matrix. J Vasc Surg. 2013;57:1362-70 pubmed 出版商
Bellussi L, Chen L, Chen D, Passali F, Passali D. The role of High Mobility Group Box 1 chromosomal protein in the pathogenesis of chronic sinusitis and nasal polyposis. Acta Otorhinolaryngol Ital. 2012;32:386-92 pubmed
Hsieh Y, Yang S, Yang C, Chou L. Dry needling at myofascial trigger spots of rabbit skeletal muscles modulates the biochemicals associated with pain, inflammation, and hypoxia. Evid Based Complement Alternat Med. 2012;2012:342165 pubmed 出版商
Klamer G, Shen S, Song E, Rice A, Knight R, Lindeman R, et al. GSK3 inhibition prevents lethal GVHD in mice. Exp Hematol. 2013;41:39-55.e10 pubmed 出版商
Gelderblom M, Weymar A, Bernreuther C, Velden J, Arunachalam P, Steinbach K, et al. Neutralization of the IL-17 axis diminishes neutrophil invasion and protects from ischemic stroke. Blood. 2012;120:3793-802 pubmed 出版商
Li J, Tang Y, Cai D. IKK?/NF-?B disrupts adult hypothalamic neural stem cells to mediate a neurodegenerative mechanism of dietary obesity and pre-diabetes. Nat Cell Biol. 2012;14:999-1012 pubmed 出版商
Shi Y, Gelman B, Lisinicchia J, Tang S. Chronic-pain-associated astrocytic reaction in the spinal cord dorsal horn of human immunodeficiency virus-infected patients. J Neurosci. 2012;32:10833-40 pubmed 出版商
Gupta G, Agrawal T, DelCore M, Mohiuddin S, Agrawal D. Vitamin D deficiency induces cardiac hypertrophy and inflammation in epicardial adipose tissue in hypercholesterolemic swine. Exp Mol Pathol. 2012;93:82-90 pubmed 出版商
Kosacka J, Nowicki M, Kloting N, Kern M, Stumvoll M, Bechmann I, et al. COMP-angiopoietin-1 recovers molecular biomarkers of neuropathy and improves vascularisation in sciatic nerve of ob/ob mice. PLoS ONE. 2012;7:e32881 pubmed 出版商
Koenders M, Marijnissen R, Joosten L, Abdollahi Roodsaz S, Di Padova F, van de Loo F, et al. T cell lessons from the rheumatoid arthritis synovium SCID mouse model: CD3-rich synovium lacks response to CTLA-4Ig but is successfully treated by interleukin-17 neutralization. Arthritis Rheum. 2012;64:1762-70 pubmed 出版商
Zhao L, Ma W, Fariss R, Wong W. Minocycline attenuates photoreceptor degeneration in a mouse model of subretinal hemorrhage microglial: inhibition as a potential therapeutic strategy. Am J Pathol. 2011;179:1265-77 pubmed 出版商
Verneuil L, Leboeuf C, Vidal J, Ratajczak P, Comoz F, Ameisen J, et al. Endothelial damage in all types of T-lymphocyte-mediated drug-induced eruptions. Arch Dermatol. 2011;147:579-84 pubmed 出版商
Portillo J, Okenka G, Reed E, Subauste A, Van Grol J, Gentil K, et al. The CD40-autophagy pathway is needed for host protection despite IFN-?-dependent immunity and CD40 induces autophagy via control of P21 levels. PLoS ONE. 2010;5:e14472 pubmed 出版商
Feng Y, Santoriello C, Mione M, Hurlstone A, Martin P. Live imaging of innate immune cell sensing of transformed cells in zebrafish larvae: parallels between tumor initiation and wound inflammation. PLoS Biol. 2010;8:e1000562 pubmed 出版商
Domitrovic R, Jakovac H, Blagojević G. Hepatoprotective activity of berberine is mediated by inhibition of TNF-?, COX-2, and iNOS expression in CCl(4)-intoxicated mice. Toxicology. 2011;280:33-43 pubmed 出版商
Cates J, Friedman D, Seeley E, Dupont W, Schwartz H, Holt G, et al. Proteomic analysis of osteogenic sarcoma: association of tumour necrosis factor with poor prognosis. Int J Exp Pathol. 2010;91:335-49 pubmed 出版商
Innamorato N, Rojo A, García Yagüe A, Yamamoto M, De Ceballos M, Cuadrado A. The transcription factor Nrf2 is a therapeutic target against brain inflammation. J Immunol. 2008;181:680-9 pubmed
Scamuffa N, Siegfried G, Bontemps Y, Ma L, Basak A, Cherel G, et al. Selective inhibition of proprotein convertases represses the metastatic potential of human colorectal tumor cells. J Clin Invest. 2008;118:352-63 pubmed
van der Heijden G, Derijck A, Pósfai E, Giele M, Pelczar P, Ramos L, et al. Chromosome-wide nucleosome replacement and H3.3 incorporation during mammalian meiotic sex chromosome inactivation. Nat Genet. 2007;39:251-8 pubmed
Mastronardi F, Wood D, Mei J, Raijmakers R, Tseveleki V, Dosch H, et al. Increased citrullination of histone H3 in multiple sclerosis brain and animal models of demyelination: a role for tumor necrosis factor-induced peptidylarginine deiminase 4 translocation. J Neurosci. 2006;26:11387-96 pubmed
产品信息
目录号 :
ab1793
ItemName :
抗肿瘤坏死因子甲抗体[52B83]
产品类型 :
一抗
宿主物种 :
小鼠
克隆性 :
单克隆
共轭标签 :
Not Conjugated
抗原修饰 :
No Modifications
克隆名称 :
52B83
规格 :
50微克
物种摘要 :
A lept, Chmp, CynMk, Gpig, Hu, Ms, RMk, Zfsh
用途 :
ELISA, Flow Cyt, ICC/IF, IHC-Fr, IHC-P, WB
规格说明 :
Other sizes available: 100 µg
公司信息
艾博抗(上海)贸易有限公司
上海市浦东新区伽利略路338号5幢4层5401室
cn.technical@abcam.com
http://www.abcam.cn
400-628-6880 86-21-5110 5938
公司总部: 英国
Abcam是全球知名的生命科学研究领域产品提供商,产品涵盖一抗、二抗、蛋白、多肽及ELISA kit。