产品简要
公司名称 :
艾博抗(上海)贸易有限公司
其他品牌 :
Epitomics, Ascent Scientific, MitoSciences
产品类型 :
抗体
产品名称 :
抗XRCC1抗体[33-2-5]
目录 :
ab1838
规格 :
250微升
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
33-2-5
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 免疫细胞化学, 免疫沉淀, 流式细胞仪, 免疫组化-石蜡切片, 免疫组化-冰冻切片
文章摘录数: 35
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 人类; 1:200
Galanos P, Pappas G, Polyzos A, Kotsinas A, Svolaki I, Giakoumakis N, et al. Mutational signatures reveal the role of RAD52 in p53-independent p21-driven genomic instability. Genome Biol. 2018;19:37 pubmed 出版商
  • 免疫细胞化学; 人类; 图 2
  • 免疫印迹; 人类; 图 1
Bj Rås K, Sousa M, Sharma A, Fonseca D, S Gaard C, Bj Rås M, et al. Monitoring of the spatial and temporal dynamics of BER/SSBR pathway proteins, including MYH, UNG2, MPG, NTH1 and NEIL1-3, during DNA replication. Nucleic Acids Res. 2017;45:8291-8301 pubmed 出版商
  • 免疫细胞化学; 小鼠; 1:50
Horton J, Gassman N, Dunigan B, Stefanick D, Wilson S. DNA polymerase β-dependent cell survival independent of XRCC1 expression. DNA Repair (Amst). 2015;26:23-9 pubmed 出版商
  • 免疫细胞化学; 人类; 图 5
  • 免疫印迹; 人类; 图 s1
Abdou I, Poirier G, Hendzel M, Weinfeld M. DNA ligase III acts as a DNA strand break sensor in the cellular orchestration of DNA strand break repair. Nucleic Acids Res. 2015;43:875-92 pubmed 出版商
  • 免疫印迹; 人类; 1:500; 图 s1d
Fang Q, Inanç B, Schamus S, Wang X, Wei L, Brown A, et al. HSP90 regulates DNA repair via the interaction between XRCC1 and DNA polymerase β. Nat Commun. 2014;5:5513 pubmed 出版商
  • 免疫印迹; 人类
Prensner J, Chen W, Iyer M, Cao Q, Ma T, Han S, et al. PCAT-1, a long noncoding RNA, regulates BRCA2 and controls homologous recombination in cancer. Cancer Res. 2014;74:1651-60 pubmed 出版商
  • 免疫细胞化学; 小鼠; 1:50
Horton J, Stefanick D, Gassman N, Williams J, Gabel S, Cuneo M, et al. Preventing oxidation of cellular XRCC1 affects PARP-mediated DNA damage responses. DNA Repair (Amst). 2013;12:774-85 pubmed 出版商
  • 免疫印迹; 人类; 图 4
Ebert F, Weiss A, Bültemeyer M, Hamann I, Hartwig A, Schwerdtle T. Arsenicals affect base excision repair by several mechanisms. Mutat Res. 2011;715:32-41 pubmed 出版商
Wu Y, Li H, Ren Y, Zou D, Zhang K, Xiao X. The association of XRCC1 polymorphism with osteosarcoma risk, clinicopathologic features, and prognosis in a Chinese Han population. Cancer Manag Res. 2018;10:4959-4967 pubmed 出版商
Saha L, Kim S, Kang H, Akter S, Choi K, Sakuma T, et al. Differential micronucleus frequency in isogenic human cells deficient in DNA repair pathways is a valuable indicator for evaluating genotoxic agents and their genotoxic mechanisms. Environ Mol Mutagen. 2018;59:529-538 pubmed 出版商
Rehman I, Basu S, Das S, Bhattacharjee S, Ghosh A, Pommier Y, et al. PRMT5-mediated arginine methylation of TDP1 for the repair of topoisomerase I covalent complexes. Nucleic Acids Res. 2018;46:5601-5617 pubmed 出版商
Wilhelm T, Ragu S, Magdalou I, Machon C, Dardillac E, Técher H, et al. Slow Replication Fork Velocity of Homologous Recombination-Defective Cells Results from Endogenous Oxidative Stress. PLoS Genet. 2016;12:e1006007 pubmed 出版商
Ávila Arroyo S, Nuñez G, García Fernández L, Galmarini C. Synergistic Effect of Trabectedin and Olaparib Combination Regimen in Breast Cancer Cell Lines. J Breast Cancer. 2015;18:329-38 pubmed 出版商
Xu Z, Zhang L, Zhang W, Meng D, Zhang H, Jiang Y, et al. SIRT6 rescues the age related decline in base excision repair in a PARP1-dependent manner. Cell Cycle. 2015;14:269-76 pubmed 出版商
Weber A, Schuermann D, Schär P. Versatile recombinant SUMOylation system for the production of SUMO-modified protein. PLoS ONE. 2014;9:e102157 pubmed 出版商
Das B, Huang S, Murai J, Rehman I, Ame J, Sengupta S, et al. PARP1-TDP1 coupling for the repair of topoisomerase I-induced DNA damage. Nucleic Acids Res. 2014;42:4435-49 pubmed 出版商
Kristensen D, Nielsen J, Jørgensen A, Skakkebæk N, Rajpert De Meyts E, Almstrup K. Evidence that active demethylation mechanisms maintain the genome of carcinoma in situ cells hypomethylated in the adult testis. Br J Cancer. 2014;110:668-78 pubmed 出版商
Masaoka A, Gassman N, Kedar P, Prasad R, Hou E, Horton J, et al. HMGN1 protein regulates poly(ADP-ribose) polymerase-1 (PARP-1) self-PARylation in mouse fibroblasts. J Biol Chem. 2012;287:27648-58 pubmed 出版商
Han L, Mao W, Yu K. X-ray repair cross-complementing protein 1 (XRCC1) deficiency enhances class switch recombination and is permissive for alternative end joining. Proc Natl Acad Sci U S A. 2012;109:4604-8 pubmed 出版商
Mohni K, Mastrocola A, Bai P, Weller S, Heinen C. DNA mismatch repair proteins are required for efficient herpes simplex virus 1 replication. J Virol. 2011;85:12241-53 pubmed 出版商
Fisher L, Bessho M, Wakasugi M, Matsunaga T, Bessho T. Role of interaction of XPF with RPA in nucleotide excision repair. J Mol Biol. 2011;413:337-46 pubmed 出版商
Paul C, Nagano M, Robaire B. Aging results in differential regulation of DNA repair pathways in pachytene spermatocytes in the Brown Norway rat. Biol Reprod. 2011;85:1269-78 pubmed 出版商
Hanssen Bauer A, Solvang Garten K, Sundheim O, Pena Diaz J, Andersen S, Slupphaug G, et al. XRCC1 coordinates disparate responses and multiprotein repair complexes depending on the nature and context of the DNA damage. Environ Mol Mutagen. 2011;52:623-35 pubmed 出版商
Akbari M, Solvang Garten K, Hanssen Bauer A, Lieske N, Pettersen H, Pettersen G, et al. Direct interaction between XRCC1 and UNG2 facilitates rapid repair of uracil in DNA by XRCC1 complexes. DNA Repair (Amst). 2010;9:785-95 pubmed 出版商
Peddi P, Loftin C, Dickey J, Hair J, Burns K, Aziz K, et al. DNA-PKcs deficiency leads to persistence of oxidatively induced clustered DNA lesions in human tumor cells. Free Radic Biol Med. 2010;48:1435-43 pubmed 出版商
Dieriks B, De Vos W, Derradji H, Baatout S, Van Oostveldt P. Medium-mediated DNA repair response after ionizing radiation is correlated with the increase of specific cytokines in human fibroblasts. Mutat Res. 2010;687:40-8 pubmed 出版商
Byrne S, Cunniffe S, O Neill P, Lomax M. 5,6-Dihydrothymine impairs the base excision repair pathway of a closely opposed AP site or single-strand break. Radiat Res. 2009;172:537-49 pubmed 出版商
Das B, Antony S, Gupta S, Dexheimer T, Redon C, Garfield S, et al. Optimal function of the DNA repair enzyme TDP1 requires its phosphorylation by ATM and/or DNA-PK. EMBO J. 2009;28:3667-80 pubmed 出版商
Zarebski M, Wiernasz E, Dobrucki J. Recruitment of heterochromatin protein 1 to DNA repair sites. Cytometry A. 2009;75:619-25 pubmed 出版商
Akbari M, Pena Diaz J, Andersen S, Liabakk N, Otterlei M, Krokan H. Extracts of proliferating and non-proliferating human cells display different base excision pathways and repair fidelity. DNA Repair (Amst). 2009;8:834-43 pubmed 出版商
Sato S, Itamochi H, Kigawa J, Oishi T, Shimada M, Sato S, et al. Combination chemotherapy of oxaliplatin and 5-fluorouracil may be an effective regimen for mucinous adenocarcinoma of the ovary: a potential treatment strategy. Cancer Sci. 2009;100:546-51 pubmed 出版商
Hong Z, Jiang J, Hashiguchi K, Hoshi M, Lan L, Yasui A. Recruitment of mismatch repair proteins to the site of DNA damage in human cells. J Cell Sci. 2008;121:3146-54 pubmed 出版商
Visnes T, Akbari M, Hagen L, Slupphaug G, Krokan H. The rate of base excision repair of uracil is controlled by the initiating glycosylase. DNA Repair (Amst). 2008;7:1869-81 pubmed 出版商
Mourgues S, Lomax M, O Neill P. Base excision repair processing of abasic site/single-strand break lesions within clustered damage sites associated with XRCC1 deficiency. Nucleic Acids Res. 2007;35:7676-87 pubmed
Mortusewicz O, Rothbauer U, Cardoso M, Leonhardt H. Differential recruitment of DNA Ligase I and III to DNA repair sites. Nucleic Acids Res. 2006;34:3523-32 pubmed
产品信息
目录号 :
ab1838
ItemName :
抗XRCC1抗体[33-2-5]
产品类型 :
抗体
宿主物种 :
小鼠
克隆性 :
单克隆
共轭标签 :
未共轭
克隆名称 :
33-2-5
规格 :
250微升
物种摘要 :
ChHm, Hu, Rat
纯度 :
蛋白质A纯化
应用摘要 :
Flow Cyt, ICC/IF, IHC-Fr, IHC-P, IP, WB
公司信息
艾博抗(上海)贸易有限公司
上海市浦东新区伽利略路338号5幢4层5401室
cn.technical@abcam.com
http://www.abcam.cn
400-628-6880 86-21-5110 5938
公司总部: 英国
Abcam是全球知名的生命科学研究领域产品提供商,产品涵盖一抗、二抗、蛋白、多肽及ELISA kit。