产品简要
公司名称 :
艾博抗(上海)贸易有限公司
其他品牌 :
Epitomics, Ascent Scientific, MitoSciences
产品类型 :
抗体
产品名称 :
抗FOXP3抗体[236A/E7]
目录 :
ab20034
规格 :
100微克
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
236a/E7
反应物种 :
人类, 小鼠
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫组化-石蜡切片, 免疫组化-冰冻切片
文章摘录数: 165
出版应用/物种/样本/稀释参考文献
  • 免疫组化; 人类; 1:50; 图 1f
Kuroda H, Jamiyan T, Yamaguchi R, Kakumoto A, Abe A, Harada O, et al. Tumor-infiltrating B cells and T cells correlate with postoperative prognosis in triple-negative carcinoma of the breast. BMC Cancer. 2021;21:286 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:100; 图 1c
Kim M, Chung Y, Kim H, Woo J, Ahn S, Park S. Immune microenvironment in ductal carcinoma in situ: a comparison with invasive carcinoma of the breast. Breast Cancer Res. 2020;22:32 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:400; 图 3a
Shima T, Shimoda M, Shigenobu T, Ohtsuka T, Nishimura T, Emoto K, et al. Infiltration of tumor-associated macrophages is involved in tumor programmed death-ligand 1 expression in early lung adenocarcinoma. Cancer Sci. 2020;111:727-738 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:50; 图 3c
Bell L, Lenhart A, Rosenwald A, Monoranu C, Berberich Siebelt F. Lymphoid Aggregates in the CNS of Progressive Multiple Sclerosis Patients Lack Regulatory T Cells. Front Immunol. 2019;10:3090 pubmed 出版商
  • 免疫组化-冰冻切片; 人类; 1:100; 图 1f
Del Duca E, Pavel A, Dubin C, Song T, Wallace E, Peng X, et al. Major Differences in Expression of Inflammatory Pathways in Skin from Different Body Sites of Healthy Individuals. J Invest Dermatol. 2019;139:2228-2232.e10 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 图 1a
Blom S, Paavolainen L, Bychkov D, Turkki R, Mäki Teeri P, Hemmes A, et al. Systems pathology by multiplexed immunohistochemistry and whole-slide digital image analysis. Sci Rep. 2017;7:15580 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:100; 图 2k
Matsuyama K, Mizutani Y, Takahashi T, Shu E, Kanoh H, Miyazaki T, et al. Enhanced dendritic cells and regulatory T cells in the dermis of porokeratosis. Arch Dermatol Res. 2017;309:749-756 pubmed 出版商
  • 免疫组化; 小鼠; 图 s3b
Funken D, Ishikawa Ankerhold H, Uhl B, Lerchenberger M, Rentsch M, Mayr D, et al. In situ targeting of dendritic cells sets tolerogenic environment and ameliorates CD4+ T-cell response in the postischemic liver. FASEB J. 2017;31:4796-4808 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 图 2c
Chew V, Lai L, Pan L, Lim C, Li J, Ong R, et al. Delineation of an immunosuppressive gradient in hepatocellular carcinoma using high-dimensional proteomic and transcriptomic analyses. Proc Natl Acad Sci U S A. 2017;114:E5900-E5909 pubmed 出版商
  • 免疫组化; 人类; 1:50; 图 2c
Su S, Liao J, Liu J, Huang D, He C, Chen F, et al. Blocking the recruitment of naive CD4+ T cells reverses immunosuppression in breast cancer. Cell Res. 2017;27:461-482 pubmed 出版商
  • 免疫印迹; 人类; 图 3D
Kempińska Podhorodecka A, Milkiewicz M, Wasik U, Ligocka J, Zawadzki M, Krawczyk M, et al. Decreased Expression of Vitamin D Receptor Affects an Immune Response in Primary Biliary Cholangitis via the VDR-miRNA155-SOCS1 Pathway. Int J Mol Sci. 2017;18: pubmed 出版商
  • 免疫组化-冰冻切片; 人类; 图 4b
Boardman D, Philippeos C, Fruhwirth G, Ibrahim M, Hannen R, Cooper D, et al. Expression of a Chimeric Antigen Receptor Specific for Donor HLA Class I Enhances the Potency of Human Regulatory T Cells in Preventing Human Skin Transplant Rejection. Am J Transplant. 2017;17:931-943 pubmed 出版商
  • 免疫组化; 人类; 图 1c
Senbabaoglu Y, Gejman R, Winer A, Liu M, Van Allen E, de Velasco G, et al. Tumor immune microenvironment characterization in clear cell renal cell carcinoma identifies prognostic and immunotherapeutically relevant messenger RNA signatures. Genome Biol. 2016;17:231 pubmed
  • 免疫组化-石蜡切片; 人类; 1:100; 图 2c
Sundara Y, Kostine M, Cleven A, Bovee J, Schilham M, Cleton Jansen A. Increased PD-L1 and T-cell infiltration in the presence of HLA class I expression in metastatic high-grade osteosarcoma: a rationale for T-cell-based immunotherapy. Cancer Immunol Immunother. 2017;66:119-128 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 20 ug/ml; 图 3a
Kaewkangsadan V, Verma C, Eremin J, Cowley G, Ilyas M, Eremin O. Crucial Contributions by T Lymphocytes (Effector, Regulatory, and Checkpoint Inhibitor) and Cytokines (TH1, TH2, and TH17) to a Pathological Complete Response Induced by Neoadjuvant Chemotherapy in Women with Breast Cancer. J Immunol Res. 2016;2016:4757405 pubmed
  • 免疫组化-石蜡切片; 人类; 图 1
Ogiya R, Niikura N, Kumaki N, Bianchini G, Kitano S, Iwamoto T, et al. Comparison of tumor-infiltrating lymphocytes between primary and metastatic tumors in breast cancer patients. Cancer Sci. 2016;107:1730-1735 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 表 3
Torrelo A, Noguera Morel L, Hernandez Martin A, Clemente D, Barja J, Buzon L, et al. Recurrent lipoatrophic panniculitis of children. J Eur Acad Dermatol Venereol. 2017;31:536-543 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 图 2b
Chen H, Händel N, Ngeow J, Muller J, Huhn M, Yang H, et al. Immune dysregulation in patients with PTEN hamartoma tumor syndrome: Analysis of FOXP3 regulatory T cells. J Allergy Clin Immunol. 2017;139:607-620.e15 pubmed 出版商
  • 免疫组化; 小鼠; 图 6b
Ashizawa T, Iizuka A, Nonomura C, Kondou R, Maeda C, Miyata H, et al. Antitumor Effect of Programmed Death-1 (PD-1) Blockade in Humanized the NOG-MHC Double Knockout Mouse. Clin Cancer Res. 2017;23:149-158 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:500; 图 3
Gu L, Deng W, Sun X, Zhou H, Xu Q. Rapamycin ameliorates CCl4-induced liver fibrosis in mice through reciprocal regulation of the Th17/Treg cell balance. Mol Med Rep. 2016;14:1153-61 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 图 1
Chen C, Liu Y, Hua M, Li X, Ji C, Ma D. Neuropathy correlated with imbalanced Foxp3/IL-17 in bone marrow microenvironment of patients with acute myeloid leukemia. Oncotarget. 2016;7:24455-65 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:100; 图 3
Friedman K, Brodsky A, Lu S, Wood S, Gill A, Lombardo K, et al. Medullary carcinoma of the colon: a distinct morphology reveals a distinctive immunoregulatory microenvironment. Mod Pathol. 2016;29:528-41 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 图 1
Nguyen N, Bellile E, Thomas D, McHugh J, Rozek L, Virani S, et al. Tumor infiltrating lymphocytes and survival in patients with head and neck squamous cell carcinoma. Head Neck. 2016;38:1074-84 pubmed 出版商
  • 免疫组化; 人类; 1:50; 表 2
Menter T, Dickenmann M, Juskevicius D, Steiger J, Dirnhofer S, Tzankov A. Comprehensive phenotypic characterization of PTLD reveals potential reliance on EBV or NF-κB signalling instead of B-cell receptor signalling. Hematol Oncol. 2017;35:187-197 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:100
Kim K, Wen X, Yang H, Kim W, Kang G. Prognostic Implication of M2 Macrophages Are Determined by the Proportional Balance of Tumor Associated Macrophages and Tumor Infiltrating Lymphocytes in Microsatellite-Unstable Gastric Carcinoma. PLoS ONE. 2015;10:e0144192 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 图 2
Feng Z, Puri S, Moudgil T, Wood W, Hoyt C, Wang C, et al. Multispectral imaging of formalin-fixed tissue predicts ability to generate tumor-infiltrating lymphocytes from melanoma. J Immunother Cancer. 2015;3:47 pubmed 出版商
  • 免疫组化-石蜡切片; 人类
Zhao L, Li C, Jin P, Ng C, Lin Z, Li Y, et al. Histopathological features of sinonasal inverted papillomas in chinese patients. Laryngoscope. 2016;126:E141-7 pubmed 出版商
  • 免疫组化; 人类; 图 5
Jasinski Bergner S, Stoehr C, Bukur J, Massa C, Braun J, Hüttelmaier S, et al. Clinical relevance of miR-mediated HLA-G regulation and the associated immune cell infiltration in renal cell carcinoma. Oncoimmunology. 2015;4:e1008805 pubmed
  • 免疫组化-石蜡切片; 人类
Punt S, van Vliet M, Spaans V, de Kroon C, Fleuren G, Gorter A, et al. FoxP3(+) and IL-17(+) cells are correlated with improved prognosis in cervical adenocarcinoma. Cancer Immunol Immunother. 2015;64:745-53 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:800
Torres Cabala C, Curry J, Li Ning Tapia E, Ramos C, Tetzlaff M, Prieto V, et al. HTLV-1-associated infective dermatitis demonstrates low frequency of FOXP3-positive T-regulatory lymphocytes. J Dermatol Sci. 2015;77:150-5 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 图 St1A
Engels C, Charehbili A, van de Velde C, Bastiaannet E, Sajet A, Putter H, et al. The prognostic and predictive value of Tregs and tumor immune subtypes in postmenopausal, hormone receptor-positive breast cancer patients treated with adjuvant endocrine therapy: a Dutch TEAM study analysis. Breast Cancer Res Treat. 2015;149:587-96 pubmed 出版商
  • 免疫组化; 人类
Däster S, Eppenberger Castori S, Hirt C, Zlobec I, Delko T, Nebiker C, et al. High frequency of CD8 positive lymphocyte infiltration correlates with lack of lymph node involvement in early rectal cancer. Dis Markers. 2014;2014:792183 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:60
Vorobjova T, Uibo O, Heilman K, Uibo R. Increased density of tolerogenic dendritic cells in the small bowel mucosa of celiac patients. World J Gastroenterol. 2015;21:439-52 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:180; 图 4
Hermans C, Anz D, Engel J, Kirchner T, Endres S, Mayr D. Analysis of FoxP3+ T-regulatory cells and CD8+ T-cells in ovarian carcinoma: location and tumor infiltration patterns are key prognostic markers. PLoS ONE. 2014;9:e111757 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 图 1
Llosa N, Cruise M, Tam A, Wicks E, Hechenbleikner E, Taube J, et al. The vigorous immune microenvironment of microsatellite instable colon cancer is balanced by multiple counter-inhibitory checkpoints. Cancer Discov. 2015;5:43-51 pubmed 出版商
  • 免疫组化; 人类; 图 1c
Zhang X, Gao L, Liang X, Guo M, Wang R, Pan Y, et al. HBV preS2 transactivates FOXP3 expression in malignant hepatocytes. Liver Int. 2015;35:1087-94 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:100
Azzimonti B, Zavattaro E, Provasi M, Vidali M, Conca A, Catalano E, et al. Intense Foxp3+ CD25+ regulatory T-cell infiltration is associated with high-grade cutaneous squamous cell carcinoma and counterbalanced by CD8+/Foxp3+ CD25+ ratio. Br J Dermatol. 2015;172:64-73 pubmed 出版商
  • 免疫组化; 人类; 1:100
Sereti I, Estes J, Thompson W, Morcock D, Fischl M, Croughs T, et al. Decreases in colonic and systemic inflammation in chronic HIV infection after IL-7 administration. PLoS Pathog. 2014;10:e1003890 pubmed 出版商
  • 免疫组化-石蜡切片; 人类
Gadiot J, Hooijkaas A, Kaiser A, Van Tinteren H, van Boven H, Blank C. Overall survival and PD-L1 expression in metastasized malignant melanoma. Cancer. 2011;117:2192-201 pubmed 出版商
Sun L, Yang K, Zhang L, Qi L, Chen J, Li P, et al. Programmed death-1 expression and regulatory T cells increase in the Intestinal mucosa of cytomegalovirus colitis in patients with HIV/AIDS. AIDS Res Ther. 2020;17:54 pubmed 出版商
Al Rajhi N, Soudy H, Ahmed S, Elhassan T, Mohammed S, Khoja H, et al. CD3+T-lymphocyte infiltration is an independent prognostic factor for advanced nasopharyngeal carcinoma. BMC Cancer. 2020;20:240 pubmed 出版商
Forstnerič V, Oven I, Ogorevc J, Lainšček D, Praznik A, Lebar T, et al. CRISPRa-mediated FOXP3 gene upregulation in mammalian cells. Cell Biosci. 2019;9:93 pubmed 出版商
Ottaiano A, Scala S, Normanno N, Napolitano M, Capozzi M, Rachiglio A, et al. Cetuximab, irinotecan and fluorouracile in fiRst-line treatment of immunologically-selected advanced colorectal cancer patients: the CIFRA study protocol. BMC Cancer. 2019;19:899 pubmed 出版商
Kuwahara T, Hazama S, Suzuki N, Yoshida S, Tomochika S, Nakagami Y, et al. Intratumoural-infiltrating CD4 + and FOXP3 + T cells as strong positive predictive markers for the prognosis of resectable colorectal cancer. Br J Cancer. 2019;121:659-665 pubmed 出版商
Klimczak A, Suchnicki K, Sedzimirska M, Lange A. Diverse Activity of IL-17+ Cells in Chronic Skin and Mucosa Graft-Versus-Host Disease. Arch Immunol Ther Exp (Warsz). 2019;: pubmed 出版商
de Groot A, Blok E, Charehbili A, Engels C, Smit V, Dekker Ensink N, et al. Strong CD8+ lymphocyte infiltration in combination with expression of HLA class I is associated with better tumor control in breast cancer patients treated with neoadjuvant chemotherapy. Breast Cancer Res Treat. 2019;175:605-615 pubmed 出版商
Lee K, Kim E, Yun J, Park Y, Do S, Chae S, et al. The prognostic and predictive value of tumor-infiltrating lymphocytes and hematologic parameters in patients with breast cancer. BMC Cancer. 2018;18:938 pubmed 出版商
Ogawara D, Soda H, Tomono H, Iwasaki K, Hara T, Jinnai S, et al. Presence of few PD-1-expressing tumor-infiltrating immune cells is a potential predictor of improved response to salvage chemotherapy following nivolumab for non-small cell lung cancer: An exploratory case series. Thorac Cancer. 2018;9:1305-1311 pubmed 出版商
Merrick D, Edwards M, Franklin W, Sugita M, Keith R, Miller Y, et al. Altered Cell-Cycle Control, Inflammation, and Adhesion in High-Risk Persistent Bronchial Dysplasia. Cancer Res. 2018;78:4971-4983 pubmed 出版商
Ruscito I, Cacsire Castillo Tong D, Vergote I, Ignat I, Stanske M, Vanderstichele A, et al. Characterisation of tumour microvessel density during progression of high-grade serous ovarian cancer: clinico-pathological impact (an OCTIPS Consortium study). Br J Cancer. 2018;119:330-338 pubmed 出版商
Dieci M, Tsvetkova V, Orvieto E, Piacentini F, Ficarra G, Griguolo G, et al. Immune characterization of breast cancer metastases: prognostic implications. Breast Cancer Res. 2018;20:62 pubmed 出版商
Xi J, Feng J, Zeng S, Huang P. Long noncoding RNA UFC1 is activated by E2F1 and exerts oncogenic properties by functioning as a ceRNA of FOXP3. Cancer Med. 2018;: pubmed 出版商
Fluxá P, Rojas Sepúlveda D, Gleisner M, Tittarelli A, Villegas P, Tapia L, et al. High CD8+ and absence of Foxp3+ T lymphocytes infiltration in gallbladder tumors correlate with prolonged patients survival. BMC Cancer. 2018;18:243 pubmed 出版商
Kaewkangsadan V, Verma C, Eremin J, Cowley G, Ilyas M, Eremin O. Tumour-draining axillary lymph nodes in patients with large and locally advanced breast cancers undergoing neoadjuvant chemotherapy (NAC): the crucial contribution of immune cells (effector, regulatory) and cytokines (Th1, Th2) to immune-mediated tum. BMC Cancer. 2018;18:123 pubmed 出版商
Riaz N, Havel J, Makarov V, Desrichard A, Urba W, Sims J, et al. Tumor and Microenvironment Evolution during Immunotherapy with Nivolumab. Cell. 2017;171:934-949.e16 pubmed 出版商
Jiménez Sánchez A, Memon D, Pourpe S, Veeraraghavan H, Li Y, Vargas H, et al. Heterogeneous Tumor-Immune Microenvironments among Differentially Growing Metastases in an Ovarian Cancer Patient. Cell. 2017;170:927-938.e20 pubmed 出版商
Taylor N, Vick S, Iglesia M, Brickey W, Midkiff B, McKinnon K, et al. Treg depletion potentiates checkpoint inhibition in claudin-low breast cancer. J Clin Invest. 2017;127:3472-3483 pubmed 出版商
Chee S, Lopez M, Mellows T, Gankande S, Moutasim K, Harris S, et al. Evaluating the effect of immune cells on the outcome of patients with mesothelioma. Br J Cancer. 2017;117:1341-1348 pubmed 出版商
Szentpetery A, Heffernan E, Gogarty M, Mellerick L, McCormack J, Haroon M, et al. Abatacept reduces synovial regulatory T-cell expression in patients with psoriatic arthritis. Arthritis Res Ther. 2017;19:158 pubmed 出版商
Saito H, Fushida S, Miyashita T, Oyama K, Yamaguchi T, Tsukada T, et al. Potential of extravasated platelet aggregation as a surrogate marker for overall survival in patients with advanced gastric cancer treated with preoperative docetaxel, cisplatin and S-1: a retrospective observational study. BMC Cancer. 2017;17:294 pubmed 出版商
Hwang H, Kim H, Kim S, Choi J, Kang C, Kim K, et al. Prognostic impact of the tumor-infiltrating regulatory T-cell (Foxp3+)/activated cytotoxic T lymphocyte (granzyme B+) ratio on resected left-sided pancreatic cancer. Oncol Lett. 2016;12:4477-4484 pubmed 出版商
Ren L, Yu Y, Wang L, Zhu Z, Lu R, Yao Z. Hypoxia-induced CCL28 promotes recruitment of regulatory T cells and tumor growth in liver cancer. Oncotarget. 2016;7:75763-75773 pubmed 出版商
Hirayama Y, Gi M, Yamano S, Tachibana H, Okuno T, Tamada S, et al. Anti-PD-L1 treatment enhances antitumor effect of everolimus in a mouse model of renal cell carcinoma. Cancer Sci. 2016;107:1736-1744 pubmed 出版商
Zhu Y, Li M, Mu D, Kong L, Zhang J, Zhao F, et al. CD8+/FOXP3+ ratio and PD-L1 expression associated with survival in pT3N0M0 stage esophageal squamous cell cancer. Oncotarget. 2016;7:71455-71465 pubmed 出版商
Tian W, Wang L, Yuan L, Duan W, Zhao W, Wang S, et al. A prognostic risk model for patients with triple negative breast cancer based on stromal natural killer cells, tumor-associated macrophages and growth-arrest specific protein 6. Cancer Sci. 2016;107:882-9 pubmed 出版商
Punt S, Dronkers E, Welters M, Goedemans R, Koljenović S, Bloemena E, et al. A beneficial tumor microenvironment in oropharyngeal squamous cell carcinoma is characterized by a high T cell and low IL-17(+) cell frequency. Cancer Immunol Immunother. 2016;65:393-403 pubmed 出版商
Muto S, Owada Y, Inoue T, Watanabe Y, Yamaura T, Fukuhara M, et al. Clinical significance of expanded Foxp3⁺ Helios⁻ regulatory T cells in patients with non-small cell lung cancer. Int J Oncol. 2015;47:2082-90 pubmed 出版商
Heeren A, de Boer E, Bleeker M, Musters R, Buist M, Kenter G, et al. Nodal metastasis in cervical cancer occurs in clearly delineated fields of immune suppression in the pelvic lymph catchment area. Oncotarget. 2015;6:32484-93 pubmed 出版商
Baine M, Turcu G, Zito C, Adeniran A, Camp R, Chen L, et al. Characterization of tumor infiltrating lymphocytes in paired primary and metastatic renal cell carcinoma specimens. Oncotarget. 2015;6:24990-5002 pubmed 出版商
Kluger H, Zito C, Barr M, Baine M, Chiang V, Sznol M, et al. Characterization of PD-L1 Expression and Associated T-cell Infiltrates in Metastatic Melanoma Samples from Variable Anatomic Sites. Clin Cancer Res. 2015;21:3052-60 pubmed 出版商
Yang Y, Chuang C, Yang H, Lu C, Sheu B. Susceptibility to pediatric Helicobacter pylori infection correlates with the host responses of regulatory and effector T cells. Pediatr Infect Dis J. 2014;33:1277-82 pubmed 出版商
Wolf G, Chepeha D, Bellile E, Nguyen A, Thomas D, McHugh J. Tumor infiltrating lymphocytes (TIL) and prognosis in oral cavity squamous carcinoma: a preliminary study. Oral Oncol. 2015;51:90-5 pubmed 出版商
Reimers M, Engels C, Putter H, Morreau H, Liefers G, Van De Velde C, et al. Prognostic value of HLA class I, HLA-E, HLA-G and Tregs in rectal cancer: a retrospective cohort study. BMC Cancer. 2014;14:486 pubmed 出版商
Engels C, Fontein D, Kuppen P, de Kruijf E, Smit V, Nortier J, et al. Immunological subtypes in breast cancer are prognostic for invasive ductal but not for invasive lobular breast carcinoma. Br J Cancer. 2014;111:532-8 pubmed 出版商
Lopes L, Guembarovski R, Guembarovski A, Kishima M, Campos C, Oda J, et al. FOXP3 transcription factor: a candidate marker for susceptibility and prognosis in triple negative breast cancer. Biomed Res Int. 2014;2014:341654 pubmed 出版商
Sjödahl G, Lövgren K, Lauss M, Chebil G, Patschan O, Gudjonsson S, et al. Infiltration of CD3? and CD68? cells in bladder cancer is subtype specific and affects the outcome of patients with muscle-invasive tumors. Urol Oncol. 2014;32:791-7 pubmed 出版商
Maeda N, Yoshimura K, Yamamoto S, Kuramasu A, Inoue M, Suzuki N, et al. Expression of B7-H3, a potential factor of tumor immune evasion in combination with the number of regulatory T cells, affects against recurrence-free survival in breast cancer patients. Ann Surg Oncol. 2014;21 Suppl 4:S546-54 pubmed 出版商
Ma G, Miao Q, Liu Y, Gao H, Lian J, Wang Y, et al. High FoxP3 expression in tumour cells predicts better survival in gastric cancer and its role in tumour microenvironment. Br J Cancer. 2014;110:1552-60 pubmed 出版商
Sun S, Fei X, Mao Y, Wang X, Garfield D, Huang O, et al. PD-1(+) immune cell infiltration inversely correlates with survival of operable breast cancer patients. Cancer Immunol Immunother. 2014;63:395-406 pubmed 出版商
Tan B, Anaka M, Deb S, Freyer C, Ebert L, Chueh A, et al. FOXP3 over-expression inhibits melanoma tumorigenesis via effects on proliferation and apoptosis. Oncotarget. 2014;5:264-76 pubmed
de Kruijf E, Engels C, van de Water W, Bastiaannet E, Smit V, Van De Velde C, et al. Tumor immune subtypes distinguish tumor subclasses with clinical implications in breast cancer patients. Breast Cancer Res Treat. 2013;142:355-64 pubmed 出版商
Zeestraten E, Reimers M, Saadatmand S, Goossens Beumer I, Dekker J, Liefers G, et al. Combined analysis of HLA class I, HLA-E and HLA-G predicts prognosis in colon cancer patients. Br J Cancer. 2014;110:459-68 pubmed 出版商
Yang Y, Liu Y, Tang S, Yang L, Yang J, Cao G, et al. Elevated Th17 cells accompanied by decreased regulatory T cells and cytokine environment in infants with biliary atresia. Pediatr Surg Int. 2013;29:1249-60 pubmed
Weed D, Walker G, De La Fuente A, Nazarian R, Vella J, Gomez Fernandez C, et al. FOXP3 subcellular localization predicts recurrence in oral squamous cell carcinoma. PLoS ONE. 2013;8:e71908 pubmed 出版商
Demir L, Yigit S, Ellidokuz H, Erten C, Somali I, Kucukzeybek Y, et al. Predictive and prognostic factors in locally advanced breast cancer: effect of intratumoral FOXP3+ Tregs. Clin Exp Metastasis. 2013;30:1047-62 pubmed 出版商
Droeser R, Obermann E, Wolf A, Wallner S, Wolf D, Tzankov A. Negligible nuclear FOXP3 expression in breast cancer epithelial cells compared with FOXP3-positive T cells. Clin Breast Cancer. 2013;13:264-70 pubmed 出版商
Andoh Y, Makino N, Yamakawa M. Dendritic cells fused with different pancreatic carcinoma cells induce different T-cell responses. Onco Targets Ther. 2013;6:29-40 pubmed 出版商
Ye J, Liu H, Hu Y, Wan G, Li J, Wang Z, et al. The clinical implication of tumoral Gal-1 expression in laryngeal squamous cell carcinomas. Clin Transl Oncol. 2013;15:608-18 pubmed 出版商
Svensson M, Andersson S, Erlandsson M, Jonsson I, Ekwall A, Andersson K, et al. Fms-like tyrosine kinase 3 ligand controls formation of regulatory T cells in autoimmune arthritis. PLoS ONE. 2013;8:e54884 pubmed 出版商
Kinoshita T, Ishii G, Hiraoka N, Hirayama S, Yamauchi C, Aokage K, et al. Forkhead box P3 regulatory T cells coexisting with cancer associated fibroblasts are correlated with a poor outcome in lung adenocarcinoma. Cancer Sci. 2013;104:409-15 pubmed 出版商
Yu H, Huang X, Liu X, Jin H, Zhang G, Zhang Q, et al. Regulatory T cells and plasmacytoid dendritic cells contribute to the immune escape of papillary thyroid cancer coexisting with multinodular non-toxic goiter. Endocrine. 2013;44:172-81 pubmed 出版商
Ye J, Liu H, Hu Y, Li P, Zhang G, Li Y. Tumoral indoleamine 2,3-dioxygenase expression predicts poor outcome in laryngeal squamous cell carcinoma. Virchows Arch. 2013;462:73-81 pubmed 出版商
Oh H, Sin J, Choi J, Park S, Lee T, Choi Y. Overexpression of CD73 in epithelial ovarian carcinoma is associated with better prognosis, lower stage, better differentiation and lower regulatory T cell infiltration. J Gynecol Oncol. 2012;23:274-81 pubmed 出版商
Gibson H, Mishra A, Chan D, Hake T, Porcu P, Wong H. Impaired proteasome function activates GATA3 in T cells and upregulates CTLA-4: relevance for Sézary syndrome. J Invest Dermatol. 2013;133:249-57 pubmed 出版商
Yoon H, Orrock J, Foster N, Sargent D, Smyrk T, Sinicrope F. Prognostic impact of FoxP3+ regulatory T cells in relation to CD8+ T lymphocyte density in human colon carcinomas. PLoS ONE. 2012;7:e42274 pubmed 出版商
Liu F, Li Y, Ren M, Zhang X, Guo X, Lang R, et al. Peritumoral FOXP3? regulatory T cell is sensitive to chemotherapy while intratumoral FOXP3? regulatory T cell is prognostic predictor of breast cancer patients. Breast Cancer Res Treat. 2012;135:459-67 pubmed 出版商
Wahlin B, Sander B, Christensson B, Ostenstad B, Holte H, Brown P, et al. Entourage: the immune microenvironment following follicular lymphoma. Blood Cancer J. 2012;2:e52 pubmed 出版商
Liu H, Zhang T, Ye J, Li H, Huang J, Li X, et al. TNF receptor-associated factor 6 in advanced non-small cell lung cancer: clinical and prognostic implications. J Cancer Res Clin Oncol. 2012;138:1853-63 pubmed 出版商
Nicodemo A, Amato V, Miranda A, Floeter Winter L, Zampieri R, Fernades E, et al. Are the severe injuries of cutaneous leishmaniasis caused by an exacerbated Th1 response?. Parasite Immunol. 2012;34:440-3 pubmed 出版商
Liu H, Zhang T, Ye J, Li H, Huang J, Li X, et al. Tumor-infiltrating lymphocytes predict response to chemotherapy in patients with advance non-small cell lung cancer. Cancer Immunol Immunother. 2012;61:1849-56 pubmed
Kuo C, Lo C, Chung F, Lee K, Lin S, Wang C, et al. Concomitant active tuberculosis prolongs survival in non-small cell lung cancer: a study in a tuberculosis-endemic country. PLoS ONE. 2012;7:e33226 pubmed 出版商
Ladoire S, Mignot G, Dalban C, Chevriaux A, Arnould L, Rébé C, et al. FOXP3 expression in cancer cells and anthracyclines efficacy in patients with primary breast cancer treated with adjuvant chemotherapy in the phase III UNICANCER-PACS 01 trial. Ann Oncol. 2012;23:2552-61 pubmed
Salama P, Stewart C, Forrest C, Platell C, Iacopetta B. FOXP3+ cell density in lymphoid follicles from histologically normal mucosa is a strong prognostic factor in early stage colon cancer. Cancer Immunol Immunother. 2012;61:1183-90 pubmed 出版商
Wansom D, Light E, Thomas D, Worden F, Prince M, Urba S, et al. Infiltrating lymphocytes and human papillomavirus-16--associated oropharyngeal cancer. Laryngoscope. 2012;122:121-7 pubmed 出版商
Wang F, Jing X, Li G, Wang T, Yang B, Zhu Z, et al. Foxp3+ regulatory T cells are associated with the natural history of chronic hepatitis B and poor prognosis of hepatocellular carcinoma. Liver Int. 2012;32:644-55 pubmed 出版商
Endo H, Saito T, Kenjo A, Hoshino M, Terashima M, Sato T, et al. Phase I trial of preoperative intratumoral injection of immature dendritic cells and OK-432 for resectable pancreatic cancer patients. J Hepatobiliary Pancreat Sci. 2012;19:465-75 pubmed 出版商
Audia S, Samson M, Guy J, Janikashvili N, Fraszczak J, Trad M, et al. Immunologic effects of rituximab on the human spleen in immune thrombocytopenia. Blood. 2011;118:4394-400 pubmed 出版商
Kim H, Kim H, Cho H, Kim S, Song K, Hyung W, et al. The ratio of intra-tumoral regulatory T cells (Foxp3+)/helper T cells (CD4+) is a prognostic factor and associated with recurrence pattern in gastric cardia cancer. J Surg Oncol. 2011;104:728-33 pubmed 出版商
Zeestraten E, van Hoesel A, Speetjens F, Menon A, Putter H, Van De Velde C, et al. FoxP3- and CD8-positive Infiltrating Immune Cells Together Determine Clinical Outcome in Colorectal Cancer. Cancer Microenviron. 2013;6:31-9 pubmed 出版商
Tao H, Mimura Y, Aoe K, Kobayashi S, Yamamoto H, Matsuda E, et al. Prognostic potential of FOXP3 expression in non-small cell lung cancer cells combined with tumor-infiltrating regulatory T cells. Lung Cancer. 2012;75:95-101 pubmed 出版商
Liu F, Lang R, Zhao J, Zhang X, Pringle G, Fan Y, et al. CD8? cytotoxic T cell and FOXP3? regulatory T cell infiltration in relation to breast cancer survival and molecular subtypes. Breast Cancer Res Treat. 2011;130:645-55 pubmed 出版商
Dimitrakopoulos F, Papadaki H, Antonacopoulou A, Kottorou A, Gotsis A, Scopa C, et al. Association of FOXP3 expression with non-small cell lung cancer. Anticancer Res. 2011;31:1677-83 pubmed
Sznurkowski J, Zawrocki A, Emerich J, Sznurkowska K, Biernat W. Expression of indoleamine 2,3-dioxygenase predicts shorter survival in patients with vulvar squamous cell carcinoma (vSCC) not influencing on the recruitment of FOXP3-expressing regulatory T cells in cancer nests. Gynecol Oncol. 2011;122:307-12 pubmed 出版商
de Boer O, Teeling P, Jansen M, Ploegmakers H, van der Loos C, Kummer J, et al. Spatial differences in the presence of FOXP3+ and GranzymeB+ T cells between the intra- and extravascular compartments in renal allograft vasculopathy. PLoS ONE. 2011;6:e18656 pubmed 出版商
Tosolini M, Kirilovsky A, Mlecnik B, Fredriksen T, Mauger S, Bindea G, et al. Clinical impact of different classes of infiltrating T cytotoxic and helper cells (Th1, th2, treg, th17) in patients with colorectal cancer. Cancer Res. 2011;71:1263-71 pubmed 出版商
Edinger J, Kant J, Swerdlow S. Cutaneous marginal zone lymphomas have distinctive features and include 2 subsets. Am J Surg Pathol. 2010;34:1830-41 pubmed 出版商
Rahman M, Midtling E, Svingen P, Xiong Y, Bell M, Tung J, et al. The pathogen recognition receptor NOD2 regulates human FOXP3+ T cell survival. J Immunol. 2010;184:7247-56 pubmed 出版商
Blatner N, Bonertz A, Beckhove P, Cheon E, Krantz S, Strouch M, et al. In colorectal cancer mast cells contribute to systemic regulatory T-cell dysfunction. Proc Natl Acad Sci U S A. 2010;107:6430-5 pubmed 出版商
Ladoire S, Arnould L, Mignot G, Coudert B, Rébé C, Chalmin F, et al. Presence of Foxp3 expression in tumor cells predicts better survival in HER2-overexpressing breast cancer patients treated with neoadjuvant chemotherapy. Breast Cancer Res Treat. 2011;125:65-72 pubmed 出版商
Oo Y, Weston C, Lalor P, Curbishley S, Withers D, Reynolds G, et al. Distinct roles for CCR4 and CXCR3 in the recruitment and positioning of regulatory T cells in the inflamed human liver. J Immunol. 2010;184:2886-98 pubmed 出版商
Battistella M, Fraitag S, Teillac D, Brousse N, De Prost Y, Bodemer C. Neonatal and early infantile cutaneous langerhans cell histiocytosis: comparison of self-regressive and non-self-regressive forms. Arch Dermatol. 2010;146:149-56 pubmed 出版商
de Kruijf E, van Nes J, Sajet A, Tummers Q, Putter H, Osanto S, et al. The predictive value of HLA class I tumor cell expression and presence of intratumoral Tregs for chemotherapy in patients with early breast cancer. Clin Cancer Res. 2010;16:1272-80 pubmed 出版商
Wahlin B, Aggarwal M, Montes Moreno S, Gonzalez L, Roncador G, Sanchez Verde L, et al. A unifying microenvironment model in follicular lymphoma: outcome is predicted by programmed death-1--positive, regulatory, cytotoxic, and helper T cells and macrophages. Clin Cancer Res. 2010;16:637-50 pubmed 出版商
Suzuki H, Chikazawa N, Tasaka T, Wada J, Yamasaki A, Kitaura Y, et al. Intratumoral CD8(+) T/FOXP3 (+) cell ratio is a predictive marker for survival in patients with colorectal cancer. Cancer Immunol Immunother. 2010;59:653-61 pubmed 出版商
Farinha P, Al Tourah A, Gill K, Klasa R, Connors J, Gascoyne R. The architectural pattern of FOXP3-positive T cells in follicular lymphoma is an independent predictor of survival and histologic transformation. Blood. 2010;115:289-95 pubmed 出版商
Karim R, Jordanova E, Piersma S, Kenter G, Chen L, Boer J, et al. Tumor-expressed B7-H1 and B7-DC in relation to PD-1+ T-cell infiltration and survival of patients with cervical carcinoma. Clin Cancer Res. 2009;15:6341-7 pubmed 出版商
Wang L, Liu R, Li W, Chen C, Katoh H, Chen G, et al. Somatic single hits inactivate the X-linked tumor suppressor FOXP3 in the prostate. Cancer Cell. 2009;16:336-46 pubmed 出版商
Katsifis G, Rekka S, Moutsopoulos N, Pillemer S, Wahl S. Systemic and local interleukin-17 and linked cytokines associated with Sjögren's syndrome immunopathogenesis. Am J Pathol. 2009;175:1167-77 pubmed 出版商
Fujishima S, Takeda H, Kawata S, Yamakawa M. The relationship between the expression of the glucocorticoid receptor in biopsied colonic mucosa and the glucocorticoid responsiveness of ulcerative colitis patients. Clin Immunol. 2009;133:208-17 pubmed 出版商
Sinicrope F, Rego R, Ansell S, Knutson K, Foster N, Sargent D. Intraepithelial effector (CD3+)/regulatory (FoxP3+) T-cell ratio predicts a clinical outcome of human colon carcinoma. Gastroenterology. 2009;137:1270-9 pubmed 出版商
Tantibhaedhyangkul U, Tatevian N, Gilger M, Major A, Davis C. Increased esophageal regulatory T cells and eosinophil characteristics in children with eosinophilic esophagitis and gastroesophageal reflux disease. Ann Clin Lab Sci. 2009;39:99-107 pubmed
Homs S, Mansour H, Desvaux D, Diet C, Hazan M, Buchler M, et al. Predominant Th1 and cytotoxic phenotype in biopsies from renal transplant recipients with transplant glomerulopathy. Am J Transplant. 2009;9:1230-6 pubmed 出版商
Camus M, Tosolini M, Mlecnik B, Pages F, Kirilovsky A, Berger A, et al. Coordination of intratumoral immune reaction and human colorectal cancer recurrence. Cancer Res. 2009;69:2685-93 pubmed 出版商
Eisenberger U, Seifried A, Patey N, Kappeler A, Noel L, Frey F, et al. FoxP3 positive T cells in graft biopsies from living donor kidney transplants after donor-specific transfusions. Transplantation. 2009;87:138-42 pubmed 出版商
Ribas A, Comin Anduix B, Economou J, Donahue T, De la Rocha P, Morris L, et al. Intratumoral immune cell infiltrates, FoxP3, and indoleamine 2,3-dioxygenase in patients with melanoma undergoing CTLA4 blockade. Clin Cancer Res. 2009;15:390-9 pubmed 出版商
Vorobjova T, Uibo O, Heilman K, Rägo T, Honkanen J, Vaarala O, et al. Increased FOXP3 expression in small-bowel mucosa of children with coeliac disease and type I diabetes mellitus. Scand J Gastroenterol. 2009;44:422-30 pubmed 出版商
Salama P, Phillips M, Grieu F, Morris M, Zeps N, Joseph D, et al. Tumor-infiltrating FOXP3+ T regulatory cells show strong prognostic significance in colorectal cancer. J Clin Oncol. 2009;27:186-92 pubmed 出版商
Estes J, Gordon S, Zeng M, Chahroudi A, Dunham R, Staprans S, et al. Early resolution of acute immune activation and induction of PD-1 in SIV-infected sooty mangabeys distinguishes nonpathogenic from pathogenic infection in rhesus macaques. J Immunol. 2008;180:6798-807 pubmed
Dainichi T, Moroi Y, Urabe K, Hashimoto T, Furue M. Vitiligo onset removes congenital nevocellular nevus cells. J Dermatol Sci. 2008;51:66-9 pubmed 出版商
Woo Y, Sterling J, Crawford R, van der Burg S, Coleman N, Stanley M. FOXP3 immunohistochemistry on formalin-fixed paraffin-embedded tissue: poor correlation between different antibodies. J Clin Pathol. 2008;61:969-71 pubmed 出版商
Tilburgs T, Roelen D, van der Mast B, de Groot Swings G, Kleijburg C, Scherjon S, et al. Evidence for a selective migration of fetus-specific CD4+CD25bright regulatory T cells from the peripheral blood to the decidua in human pregnancy. J Immunol. 2008;180:5737-45 pubmed
Qin S, Sui Y, Soloff A, Junecko B, Kirschner D, Murphey Corb M, et al. Chemokine and cytokine mediated loss of regulatory T cells in lymph nodes during pathogenic simian immunodeficiency virus infection. J Immunol. 2008;180:5530-6 pubmed
Jordanova E, Gorter A, Ayachi O, Prins F, Durrant L, Kenter G, et al. Human leukocyte antigen class I, MHC class I chain-related molecule A, and CD8+/regulatory T-cell ratio: which variable determines survival of cervical cancer patients?. Clin Cancer Res. 2008;14:2028-35 pubmed 出版商
Fox B, Bignone P, Brown P, Banham A. Defense of the clone: antibody 259D effectively labels human FOXP3 in a variety of applications. Blood. 2008;111:3897-9 pubmed 出版商
Popmihajlov Z, Smith K. Negative feedback regulation of T cells via interleukin-2 and FOXP3 reciprocity. PLoS ONE. 2008;3:e1581 pubmed 出版商
Tuovinen H, Kekäläinen E, Rossi L, Puntila J, Arstila T. Cutting edge: human CD4-CD8- thymocytes express FOXP3 in the absence of a TCR. J Immunol. 2008;180:3651-4 pubmed
Takegawa S, Jin Z, Nakayama T, Oyama T, Hieshima K, Nagakubo D, et al. Expression of CCL17 and CCL22 by latent membrane protein 1-positive tumor cells in age-related Epstein-Barr virus-associated B-cell lymphoproliferative disorder. Cancer Sci. 2008;99:296-302 pubmed 出版商
Li Y, Paczesny S, Lauret E, Poirault S, Bordigoni P, Mekhloufi F, et al. Human mesenchymal stem cells license adult CD34+ hemopoietic progenitor cells to differentiate into regulatory dendritic cells through activation of the Notch pathway. J Immunol. 2008;180:1598-608 pubmed
van der Loos C. Multiple immunoenzyme staining: methods and visualizations for the observation with spectral imaging. J Histochem Cytochem. 2008;56:313-28 pubmed
Pillai V, Karandikar N. Attack on the clones? Human FOXP3 detection by PCH101, 236A/E7, 206D, and 259D reveals 259D as the outlier with lower sensitivity. Blood. 2008;111:463-4; author reply 464-6 pubmed
Kang S, Lim H, Andrisani O, Broxmeyer H, Kim C. Vitamin A metabolites induce gut-homing FoxP3+ regulatory T cells. J Immunol. 2007;179:3724-33 pubmed
de Boer O, van der Meer J, Teeling P, van der Loos C, van der Wal A. Low numbers of FOXP3 positive regulatory T cells are present in all developmental stages of human atherosclerotic lesions. PLoS ONE. 2007;2:e779 pubmed
Senechal B, Elain G, Jeziorski E, Grondin V, Patey Mariaud de Serre N, Jaubert F, et al. Expansion of regulatory T cells in patients with Langerhans cell histiocytosis. PLoS Med. 2007;4:e253 pubmed
Malmhall C, Bossios A, Pullerits T, Lotvall J. Effects of pollen and nasal glucocorticoid on FOXP3+, GATA-3+ and T-bet+ cells in allergic rhinitis. Allergy. 2007;62:1007-13 pubmed
Orihara K, Narita M, Tobe T, Akasawa A, Ohya Y, Matsumoto K, et al. Circulating Foxp3+CD4+ cell numbers in atopic patients and healthy control subjects. J Allergy Clin Immunol. 2007;120:960-2 pubmed
Zen Y, Fujii T, Harada K, Kawano M, Yamada K, Takahira M, et al. Th2 and regulatory immune reactions are increased in immunoglobin G4-related sclerosing pancreatitis and cholangitis. Hepatology. 2007;45:1538-46 pubmed
de Boer O, van der Loos C, Teeling P, van der Wal A, Teunissen M. Immunohistochemical analysis of regulatory T cell markers FOXP3 and GITR on CD4+CD25+ T cells in normal skin and inflammatory dermatoses. J Histochem Cytochem. 2007;55:891-8 pubmed
Piersma S, Jordanova E, van Poelgeest M, Kwappenberg K, van der Hulst J, Drijfhout J, et al. High number of intraepithelial CD8+ tumor-infiltrating lymphocytes is associated with the absence of lymph node metastases in patients with large early-stage cervical cancer. Cancer Res. 2007;67:354-61 pubmed
Bates G, Fox S, Han C, Leek R, Garcia J, Harris A, et al. Quantification of regulatory T cells enables the identification of high-risk breast cancer patients and those at risk of late relapse. J Clin Oncol. 2006;24:5373-80 pubmed
Uhlig H, Coombes J, Mottet C, Izcue A, Thompson C, Fanger A, et al. Characterization of Foxp3+CD4+CD25+ and IL-10-secreting CD4+CD25+ T cells during cure of colitis. J Immunol. 2006;177:5852-60 pubmed
Rad R, Brenner L, Bauer S, Schwendy S, Layland L, da Costa C, et al. CD25+/Foxp3+ T cells regulate gastric inflammation and Helicobacter pylori colonization in vivo. Gastroenterology. 2006;131:525-37 pubmed
Grabenbauer G, Lahmer G, Distel L, Niedobitek G. Tumor-infiltrating cytotoxic T cells but not regulatory T cells predict outcome in anal squamous cell carcinoma. Clin Cancer Res. 2006;12:3355-60 pubmed
Zorn E, Nelson E, Mohseni M, Porcheray F, Kim H, Litsa D, et al. IL-2 regulates FOXP3 expression in human CD4+CD25+ regulatory T cells through a STAT-dependent mechanism and induces the expansion of these cells in vivo. Blood. 2006;108:1571-9 pubmed
Roncador G, Brown P, Maestre L, Hue S, Martinez Torrecuadrada J, Ling K, et al. Analysis of FOXP3 protein expression in human CD4+CD25+ regulatory T cells at the single-cell level. Eur J Immunol. 2005;35:1681-91 pubmed
Alvaro T, Lejeune M, Salvadó M, Bosch R, Garcia J, Jaén J, et al. Outcome in Hodgkin's lymphoma can be predicted from the presence of accompanying cytotoxic and regulatory T cells. Clin Cancer Res. 2005;11:1467-73 pubmed
产品信息
目录号 :
ab20034
ItemName :
抗FOXP3抗体[236A/E7]
产品类型 :
一抗
宿主物种 :
小鼠
克隆性 :
单克隆
共轭标签 :
Not Conjugated
抗原修饰 :
No Modifications
克隆名称 :
236A/E7
规格 :
100微克
物种摘要 :
CynMk, Hu, RMk
用途 :
ICC/IF, IHC-Fr, IHC-P, WB
规格说明 :
Other sizes available: 100 µl,250 µg
公司信息
艾博抗(上海)贸易有限公司
上海市浦东新区伽利略路338号5幢4层5401室
cn.technical@abcam.com
http://www.abcam.cn
400-628-6880 86-21-5110 5938
公司总部: 英国
Abcam是全球知名的生命科学研究领域产品提供商,产品涵盖一抗、二抗、蛋白、多肽及ELISA kit。