产品简要
公司名称 :
艾博抗(上海)贸易有限公司
其他品牌 :
Epitomics, Ascent Scientific, MitoSciences
产品类型 :
抗体
产品名称 :
抗Mre11抗体[12D7]
目录 :
ab214
规格 :
100微升
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
12D7
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 免疫细胞化学, 免疫沉淀, 流式细胞仪, 免疫组化-石蜡切片, 免疫组化-冰冻切片
文章摘录数: 25
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 人类; 1:1000; 图 1s1d
Onn L, Portillo M, Ilic S, Cleitman G, Stein D, Kaluski S, et al. SIRT6 is a DNA double-strand break sensor. elife. 2020;9: pubmed 出版商
  • 免疫印迹; 小鼠; 图 4a
  • 免疫印迹; 人类; 图 s9a
Lei L, Chen H, Xue W, Yang B, Hu B, Wei J, et al. APOBEC3 induces mutations during repair of CRISPR-Cas9-generated DNA breaks. Nat Struct Mol Biol. 2018;25:45-52 pubmed 出版商
  • 免疫沉淀; 人类; 图 5a
Clynes D, Jelinska C, Xella B, Ayyub H, Scott C, Mitson M, et al. Suppression of the alternative lengthening of telomere pathway by the chromatin remodelling factor ATRX. Nat Commun. 2015;6:7538 pubmed 出版商
  • 免疫印迹; 小鼠; 图 5a
  • 免疫印迹; 人类; 图 s1c
Petroni M, Sardina F, Heil C, Sahún Roncero M, Colicchia V, Veschi V, et al. The MRN complex is transcriptionally regulated by MYCN during neural cell proliferation to control replication stress. Cell Death Differ. 2016;23:197-206 pubmed 出版商
  • 免疫印迹; 人类; 1:500; 图 s2
Larsen D, Hari F, Clapperton J, Gwerder M, Gutsche K, Altmeyer M, et al. The NBS1-Treacle complex controls ribosomal RNA transcription in response to DNA damage. Nat Cell Biol. 2014;16:792-803 pubmed 出版商
  • 免疫细胞化学; 小鼠
Clynes D, Jelinska C, Xella B, Ayyub H, Taylor S, Mitson M, et al. ATRX dysfunction induces replication defects in primary mouse cells. PLoS ONE. 2014;9:e92915 pubmed 出版商
  • 免疫细胞化学; 人类; 1:200 and 1:750
  • 免疫印迹; 人类
Becker A, Durante M, Taucher Scholz G, Jakob B. ATM alters the otherwise robust chromatin mobility at sites of DNA double-strand breaks (DSBs) in human cells. PLoS ONE. 2014;9:e92640 pubmed 出版商
  • 免疫印迹; 人类
Martin R, Kerr M, Teo M, Jevons S, Koritzinsky M, Wouters B, et al. Post-transcriptional regulation of MRE11 expression in muscle-invasive bladder tumours. Oncotarget. 2014;5:993-1003 pubmed
  • 免疫细胞化学; 人类; 1:1000
  • 免疫印迹; 人类; 1:500-1:1000
Birkenkamp Demtroder K, Hahn S, Mansilla F, Thorsen K, Maghnouj A, Christensen R, et al. Keratin23 (KRT23) knockdown decreases proliferation and affects the DNA damage response of colon cancer cells. PLoS ONE. 2013;8:e73593 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:200
Zhang Z, Liu Y, Yin X, Zhan P, Gu Y, Ni X. Loss of BRCA1 expression leads to worse survival in patients with gastric carcinoma. World J Gastroenterol. 2013;19:1968-74 pubmed 出版商
Ye Z, Xu S, Shi Y, Bacolla A, Syed A, Moiani D, et al. GRB2 enforces homology-directed repair initiation by MRE11. Sci Adv. 2021;7: pubmed 出版商
Na J, Newman J, Then C, Syed J, Vendrell I, Torrecilla I, et al. SPRTN protease-cleaved MRE11 decreases DNA repair and radiosensitises cancer cells. Cell Death Dis. 2021;12:165 pubmed 出版商
Thuault S, Mamelonet C, Salameh J, Ostacolo K, Chanez B, Salaün D, et al. A proximity-labeling proteomic approach to investigate invadopodia molecular landscape in breast cancer cells. Sci Rep. 2020;10:6787 pubmed 出版商
Cowman S, Fan Y, Pizer B, See V. Decrease of Nibrin expression in chronic hypoxia is associated with hypoxia-induced chemoresistance in some brain tumour cells. BMC Cancer. 2019;19:300 pubmed 出版商
Ho V, Chung L, Singh A, Lea V, Abubakar A, Lim S, et al. Overexpression of the MRE11-RAD50-NBS1 (MRN) complex in rectal cancer correlates with poor response to neoadjuvant radiotherapy and prognosis. BMC Cancer. 2018;18:869 pubmed 出版商
Walker A, Kartsonaki C, Collantes E, Nicholson J, Gilbert D, Kiltie A. No additional prognostic value for MRE11 in squamous cell carcinomas of the anus treated with chemo-radiotherapy. Br J Cancer. 2017;117:322-325 pubmed 出版商
Qu J, Sun W, Zhong J, Lv H, Zhu M, Xu J, et al. Phosphoglycerate mutase 1 regulates dNTP pool and promotes homologous recombination repair in cancer cells. J Cell Biol. 2017;216:409-424 pubmed 出版商
Chen W, Ebelt N, Stracker T, Xhemalce B, Van Den Berg C, Miller K. ATM regulation of IL-8 links oxidative stress to cancer cell migration and invasion. elife. 2015;4: pubmed 出版商
Jarboui M, Bidoia C, Woods E, Roe B, Wynne K, Elia G, et al. Nucleolar protein trafficking in response to HIV-1 Tat: rewiring the nucleolus. PLoS ONE. 2012;7:e48702 pubmed 出版商
Quennet V, Beucher A, Barton O, Takeda S, Lobrich M. CtIP and MRN promote non-homologous end-joining of etoposide-induced DNA double-strand breaks in G1. Nucleic Acids Res. 2011;39:2144-52 pubmed 出版商
Choudhury A, Nelson L, Teo M, Chilka S, Bhattarai S, Johnston C, et al. MRE11 expression is predictive of cause-specific survival following radical radiotherapy for muscle-invasive bladder cancer. Cancer Res. 2010;70:7017-26 pubmed 出版商
Ali Fehmi R, Chatterjee M, Ionan A, Levin N, Arabi H, Bandyopadhyay S, et al. Analysis of the expression of human tumor antigens in ovarian cancer tissues. Cancer Biomark. 2010;6:33-48 pubmed 出版商
Kadaja M, Isok Paas H, Laos T, Ustav E, Ustav M. Mechanism of genomic instability in cells infected with the high-risk human papillomaviruses. PLoS Pathog. 2009;5:e1000397 pubmed 出版商
Stagno d Alcontres M, Mendez Bermudez A, Foxon J, Royle N, Salomoni P. Lack of TRF2 in ALT cells causes PML-dependent p53 activation and loss of telomeric DNA. J Cell Biol. 2007;179:855-67 pubmed
Buck D, Malivert L, de Chasseval R, Barraud A, Fondaneche M, Sanal O, et al. Cernunnos, a novel nonhomologous end-joining factor, is mutated in human immunodeficiency with microcephaly. Cell. 2006;124:287-99 pubmed
产品信息
目录号 :
ab214
ItemName :
抗Mre11抗体[12D7]
产品类型 :
抗体
宿主物种 :
小鼠
克隆性 :
单克隆
共轭标签 :
未共轭
克隆名称 :
12D7
规格 :
100微升
物种摘要 :
Hu, Ms, Rat
纯度 :
蛋白质G纯化
应用摘要 :
Flow Cyt, ICC/IF, IHC-Fr, IHC-P, IP, WB
公司信息
艾博抗(上海)贸易有限公司
上海市浦东新区伽利略路338号5幢4层5401室
cn.technical@abcam.com
http://www.abcam.cn
400-628-6880 86-21-5110 5938
公司总部: 英国
Abcam是全球知名的生命科学研究领域产品提供商,产品涵盖一抗、二抗、蛋白、多肽及ELISA kit。