产品简要
公司名称 :
艾博抗(上海)贸易有限公司
其他品牌 :
Epitomics, Ascent Scientific, MitoSciences
产品类型 :
抗体
产品名称 :
抗HIF-1甲抗体-ChIP级
目录 :
ab2185
规格 :
100微升
克隆性 :
多克隆
宿主 :
共轭标签 :
nonconjugated
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 免疫细胞化学, 免疫沉淀, 染色质免疫沉淀 , 免疫组化-石蜡切片, 免疫组化-冰冻切片, ChIP-Seq
文章摘录数: 52
出版应用/物种/样品/稀释参考文献
  • 免疫组化-石蜡切片; 人类; 1:8000; 图 9c
Juhasz A, Markel S, Gaur S, Liu H, Lu J, Jiang G, et al. NADPH oxidase 1 supports proliferation of colon cancer cells by modulating reactive oxygen species-dependent signal transduction. J Biol Chem. 2017;292:7866-7887 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 图 8a
Lajko M, Cardona H, Taylor J, Shah R, Farrow K, Fawzi A. Hyperoxia-Induced Proliferative Retinopathy: Early Interruption of Retinal Vascular Development with Severe and Irreversible Neurovascular Disruption. PLoS ONE. 2016;11:e0166886 pubmed 出版商
  • 免疫印迹; 人类; 图 s7
Kwak J, Lee N, Lee H, Hong I, Nam J. HIF2?/EFEMP1 cascade mediates hypoxic effects on breast cancer stem cell hierarchy. Oncotarget. 2016;7:43518-43533 pubmed 出版商
  • 染色质免疫沉淀 ; 人类; 1:150; 图 3b
  • 免疫细胞化学; 人类; 1:500; 图 6b
Brooks D, Schwab L, Krutilina R, Parke D, Sethuraman A, Hoogewijs D, et al. ITGA6 is directly regulated by hypoxia-inducible factors and enriches for cancer stem cell activity and invasion in metastatic breast cancer models. Mol Cancer. 2016;15:26 pubmed 出版商
  • ChIP-Seq; 人类; 图 2
de Bruin A, A Cornelissen P, Kirchmaier B, Mokry M, Iich E, Nirmala E, et al. Genome-wide analysis reveals NRP1 as a direct HIF1?-E2F7 target in the regulation of motorneuron guidance in vivo. Nucleic Acids Res. 2016;44:3549-66 pubmed 出版商
  • 免疫印迹; 小鼠; 图 6
David V, Martin A, Isakova T, Spaulding C, Qi L, Ramirez V, et al. Inflammation and functional iron deficiency regulate fibroblast growth factor 23 production. Kidney Int. 2016;89:135-46 pubmed 出版商
  • 染色质免疫沉淀 ; 人类; 图 2
Shen G, Ning N, Zhao X, Liu X, Wang G, Wang T, et al. Adipose differentiation-related protein is not involved in hypoxia inducible factor-1-induced lipid accumulation under hypoxia. Mol Med Rep. 2015;12:8055-61 pubmed 出版商
  • 染色质免疫沉淀 ; 人类; 图 5
  • 免疫沉淀; 人类
  • 免疫印迹; 人类
Kumar P, Gullberg U, Olsson I, Ajore R. Myeloid translocation gene-16 co-repressor promotes degradation of hypoxia-inducible factor 1. PLoS ONE. 2015;10:e0123725 pubmed 出版商
  • 免疫细胞化学; 人类; 1:1000; 图 s1c
  • 免疫印迹; 人类; 1:1000; 图 4a
Joseph J, Conroy S, Pavlov K, Sontakke P, Tomar T, Eggens Meijer E, et al. Hypoxia enhances migration and invasion in glioblastoma by promoting a mesenchymal shift mediated by the HIF1α-ZEB1 axis. Cancer Lett. 2015;359:107-16 pubmed 出版商
  • 免疫印迹; 人类; 1:500
Bakirtzi K, West G, Fiocchi C, Law I, Iliopoulos D, Pothoulakis C. The neurotensin-HIF-1α-VEGFα axis orchestrates hypoxia, colonic inflammation, and intestinal angiogenesis. Am J Pathol. 2014;184:3405-14 pubmed 出版商
  • 免疫印迹; 人类; 图 2
Paatero I, Seagroves T, Vaparanta K, Han W, Jones F, Johnson R, et al. Hypoxia-inducible factor-1? induces ErbB4 signaling in the differentiating mammary gland. J Biol Chem. 2014;289:22459-69 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:100
Cheverud J, Lawson H, Bouckaert K, Kossenkov A, Showe L, Cort L, et al. Fine-mapping quantitative trait loci affecting murine external ear tissue regeneration in the LG/J by SM/J advanced intercross line. Heredity (Edinb). 2014;112:508-18 pubmed 出版商
  • 染色质免疫沉淀 ; 小鼠
Ronkainen V, Tuomainen T, Huusko J, Laidinen S, Malinen M, Palvimo J, et al. Hypoxia-inducible factor 1-induced G protein-coupled receptor 35 expression is an early marker of progressive cardiac remodelling. Cardiovasc Res. 2014;101:69-77 pubmed 出版商
Shi Q, Liu X, Wang N, Zheng X, Fu J, Zheng J. Nitric oxide from brain microvascular endothelial cells may initiate the compensatory response to mild hypoxia of astrocytes in a hypoxia-inducible factor-1? dependent manner. Am J Transl Res. 2016;8:4735-4749 pubmed
Bayin N, Frenster J, Kane J, Rubenstein J, Modrek A, Baitalmal R, et al. GPR133 (ADGRD1), an adhesion G-protein-coupled receptor, is necessary for glioblastoma growth. Oncogenesis. 2016;5:e263 pubmed 出版商
Thuringer D, Boucher J, Jego G, Pernet N, Cronier L, Hammann A, et al. Transfer of functional microRNAs between glioblastoma and microvascular endothelial cells through gap junctions. Oncotarget. 2016;7:73925-73934 pubmed 出版商
Li C, Liu J, Yu B, Liu R, Dong C, Li S. Notch signaling represses hypoxia-inducible factor-1?-induced activation of Wnt/?-catenin signaling in osteoblasts under cobalt-mimicked hypoxia. Mol Med Rep. 2016;14:689-96 pubmed 出版商
Suyama K, Silagi E, Choi H, Sakabe K, Mochida J, Shapiro I, et al. Circadian factors BMAL1 and ROR? control HIF-1? transcriptional activity in nucleus pulposus cells: implications in maintenance of intervertebral disc health. Oncotarget. 2016;7:23056-71 pubmed 出版商
Lee J, Shin J, Shim H, Lee C, Kim D, Kim Y, et al. Autophagy contributes to the chemo-resistance of non-small cell lung cancer in hypoxic conditions. Respir Res. 2015;16:138 pubmed 出版商
Paolillo R, Spinello I, Quaranta M, Pasquini L, Pelosi E, Lo Coco F, et al. Human TM9SF4 Is a New Gene Down-Regulated by Hypoxia and Involved in Cell Adhesion of Leukemic Cells. PLoS ONE. 2015;10:e0126968 pubmed 出版商
Wang F, Zhang G, Xing T, Lu Z, Li J, Peng C, et al. Renalase contributes to the renal protection of delayed ischaemic preconditioning via the regulation of hypoxia-inducible factor-1α. J Cell Mol Med. 2015;19:1400-9 pubmed 出版商
Wong W, Richardson T, Seykora J, Cotsarelis G, Simon M. Hypoxia-inducible factors regulate filaggrin expression and epidermal barrier function. J Invest Dermatol. 2015;135:454-461 pubmed 出版商
Vavilala D, Ponnaluri V, Kanjilal D, Mukherji M. Evaluation of anti-HIF and anti-angiogenic properties of honokiol for the treatment of ocular neovascular diseases. PLoS ONE. 2014;9:e113717 pubmed 出版商
Zecchini V, Madhu B, Russell R, Pértega Gomes N, Warren A, Gaude E, et al. Nuclear ARRB1 induces pseudohypoxia and cellular metabolism reprogramming in prostate cancer. EMBO J. 2014;33:1365-82 pubmed 出版商
Chen X, Iliopoulos D, Zhang Q, Tang Q, Greenblatt M, Hatziapostolou M, et al. XBP1 promotes triple-negative breast cancer by controlling the HIF1? pathway. Nature. 2014;508:103-107 pubmed 出版商
Vorrink S, Severson P, Kulak M, Futscher B, Domann F. Hypoxia perturbs aryl hydrocarbon receptor signaling and CYP1A1 expression induced by PCB 126 in human skin and liver-derived cell lines. Toxicol Appl Pharmacol. 2014;274:408-16 pubmed 出版商
Rathnasamy G, Ling E, Kaur C. Hypoxia inducible factor-1? mediates iron uptake which induces inflammatory response in amoeboid microglial cells in developing periventricular white matter through MAP kinase pathway. Neuropharmacology. 2014;77:428-40 pubmed 出版商
Metheni M, Echebli N, Chaussepied M, Ransy C, Chereau C, Jensen K, et al. The level of H?O? type oxidative stress regulates virulence of Theileria-transformed leukocytes. Cell Microbiol. 2014;16:269-79 pubmed 出版商
Taniguchi C, Finger E, Krieg A, Wu C, Diep A, LaGory E, et al. Cross-talk between hypoxia and insulin signaling through Phd3 regulates hepatic glucose and lipid metabolism and ameliorates diabetes. Nat Med. 2013;19:1325-30 pubmed 出版商
Sundelin J, Lidberg U, Nik A, Carlsson P, Boren J. Hypoxia-induced regulation of the very low density lipoprotein receptor. Biochem Biophys Res Commun. 2013;437:274-9 pubmed 出版商
Yi T, Papadopoulos E, Hagner P, Wagner G. Hypoxia-inducible factor-1? (HIF-1?) promotes cap-dependent translation of selective mRNAs through up-regulating initiation factor eIF4E1 in breast cancer cells under hypoxia conditions. J Biol Chem. 2013;288:18732-42 pubmed 出版商
Rajendran R, Garva R, Ashour H, Leung T, Stratford I, Krstic Demonacos M, et al. Acetylation mediated by the p300/CBP-associated factor determines cellular energy metabolic pathways in cancer. Int J Oncol. 2013;42:1961-72 pubmed 出版商
Grimm M, Alexander D, Munz A, Hoffmann J, Reinert S. Increased LDH5 expression is associated with lymph node metastasis and outcome in oral squamous cell carcinoma. Clin Exp Metastasis. 2013;30:529-40 pubmed 出版商
Villar D, Ortiz Barahona A, Gómez Maldonado L, Pescador N, Sanchez Cabo F, Hackl H, et al. Cooperativity of stress-responsive transcription factors in core hypoxia-inducible factor binding regions. PLoS ONE. 2012;7:e45708 pubmed 出版商
Weijts B, Bakker W, Cornelissen P, Liang K, Schaftenaar F, Westendorp B, et al. E2F7 and E2F8 promote angiogenesis through transcriptional activation of VEGFA in cooperation with HIF1. EMBO J. 2012;31:3871-84 pubmed 出版商
Zhou W, Choi M, Margineantu D, Margaretha L, Hesson J, Cavanaugh C, et al. HIF1? induced switch from bivalent to exclusively glycolytic metabolism during ESC-to-EpiSC/hESC transition. EMBO J. 2012;31:2103-16 pubmed 出版商
Doublier S, Belisario D, Polimeni M, Annaratone L, Riganti C, Allia E, et al. HIF-1 activation induces doxorubicin resistance in MCF7 3-D spheroids via P-glycoprotein expression: a potential model of the chemo-resistance of invasive micropapillary carcinoma of the breast. BMC Cancer. 2012;12:4 pubmed 出版商
Wollenick K, Hu J, Kristiansen G, Schraml P, Rehrauer H, Berchner Pfannschmidt U, et al. Synthetic transactivation screening reveals ETV4 as broad coactivator of hypoxia-inducible factor signaling. Nucleic Acids Res. 2012;40:1928-43 pubmed 出版商
Hu J, Stiehl D, Setzer C, Wichmann D, Shinde D, Rehrauer H, et al. Interaction of HIF and USF signaling pathways in human genes flanked by hypoxia-response elements and E-box palindromes. Mol Cancer Res. 2011;9:1520-36 pubmed 出版商
Shen G, Zhao Y, Chen M, Zhang F, Liu X, Wang Y, et al. Hypoxia-inducible factor-1 (HIF-1) promotes LDL and VLDL uptake through inducing VLDLR under hypoxia. Biochem J. 2012;441:675-83 pubmed 出版商
Vanhorebeek I, Gunst J, Derde S, Derese I, Boussemaere M, Guiza F, et al. Insufficient activation of autophagy allows cellular damage to accumulate in critically ill patients. J Clin Endocrinol Metab. 2011;96:E633-45 pubmed 出版商
Gaber T, Schellmann S, Erekul K, Fangradt M, Tykwinska K, Hahne M, et al. Macrophage migration inhibitory factor counterregulates dexamethasone-mediated suppression of hypoxia-inducible factor-1 alpha function and differentially influences human CD4+ T cell proliferation under hypoxia. J Immunol. 2011;186:764-74 pubmed 出版商
Satoh M, Fujimoto S, Horike H, Ozeki M, Nagasu H, Tomita N, et al. Mitochondrial damage-induced impairment of angiogenesis in the aging rat kidney. Lab Invest. 2011;91:190-202 pubmed 出版商
Pescador N, Villar D, Cifuentes D, Garcia Rocha M, Ortiz Barahona A, Vazquez S, et al. Hypoxia promotes glycogen accumulation through hypoxia inducible factor (HIF)-mediated induction of glycogen synthase 1. PLoS ONE. 2010;5:e9644 pubmed 出版商
Ortiz Barahona A, Villar D, Pescador N, Amigo J, del Peso L. Genome-wide identification of hypoxia-inducible factor binding sites and target genes by a probabilistic model integrating transcription-profiling data and in silico binding site prediction. Nucleic Acids Res. 2010;38:2332-45 pubmed 出版商
Zhang Z, Sun H, Dai H, Walsh R, Imakura M, Schelter J, et al. MicroRNA miR-210 modulates cellular response to hypoxia through the MYC antagonist MNT. Cell Cycle. 2009;8:2756-68 pubmed
Pina Oviedo S, Khalili K, Del Valle L. Hypoxia inducible factor-1 alpha activation of the JCV promoter: role in the pathogenesis of progressive multifocal leukoencephalopathy. Acta Neuropathol. 2009;118:235-47 pubmed 出版商
Acosta Iborra B, Elorza A, Olazabal I, Martín Cófreces N, Martin Puig S, Miró M, et al. Macrophage oxygen sensing modulates antigen presentation and phagocytic functions involving IFN-gamma production through the HIF-1 alpha transcription factor. J Immunol. 2009;182:3155-64 pubmed 出版商
Beyer S, Kristensen M, Jensen K, Johansen J, Staller P. The histone demethylases JMJD1A and JMJD2B are transcriptional targets of hypoxia-inducible factor HIF. J Biol Chem. 2008;283:36542-52 pubmed 出版商
Sahlgren C, Gustafsson M, Jin S, Poellinger L, Lendahl U. Notch signaling mediates hypoxia-induced tumor cell migration and invasion. Proc Natl Acad Sci U S A. 2008;105:6392-7 pubmed 出版商
Zheng X, Linke S, Dias J, Zheng X, Gradin K, Wallis T, et al. Interaction with factor inhibiting HIF-1 defines an additional mode of cross-coupling between the Notch and hypoxia signaling pathways. Proc Natl Acad Sci U S A. 2008;105:3368-73 pubmed 出版商
Belaidi E, Beguin P, Levy P, Ribuot C, Godin Ribuot D. Prevention of HIF-1 activation and iNOS gene targeting by low-dose cadmium results in loss of myocardial hypoxic preconditioning in the rat. Am J Physiol Heart Circ Physiol. 2008;294:H901-8 pubmed
产品信息
目录号 :
ab2185
ItemName :
抗HIF-1甲抗体-ChIP级
产品类型 :
一抗
宿主物种 :
克隆性 :
多克隆
共轭标签 :
Not Conjugated
抗原修饰 :
No Modifications
规格 :
100微升
物种摘要 :
Gpig, Hu, Mk, Ms, Rat, Xl
用途 :
ChIP, GSA, ICC, ICC/IF, IHC-Fr, IHC-P, IP, WB
公司信息
艾博抗(上海)贸易有限公司
上海市浦东新区伽利略路338号5幢4层5401室
cn.technical@abcam.com
www.abcam.cn
400-628-6880 86-21-5110 5938
公司总部: 英国
Abcam是全球知名的生命科学研究领域产品提供商,产品涵盖一抗、二抗、蛋白、多肽及ELISA kit。