产品简要
公司名称 :
艾博抗(上海)贸易有限公司
其他品牌 :
Epitomics, Ascent Scientific, MitoSciences
产品类型 :
抗体
产品名称 :
抗Toll样受体4抗体[76B357.1]
目录 :
ab22048
规格 :
100微克
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
76B357.1
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学, 流式细胞仪, 免疫组化-石蜡切片, 免疫组化-冰冻切片
文章摘录数: 56
出版应用/物种/样本/稀释参考文献
  • 免疫组化; 大鼠; 图 4a
  • 免疫印迹; 大鼠; 图 4b
Jiang T, Xu S, Shen Y, Xu Y, Li Y. Genistein Attenuates Isoflurane-Induced Neuroinflammation by Inhibiting TLR4-Mediated Microglial-Polarization in vivo and in vitro. J Inflamm Res. 2021;14:2587-2600 pubmed 出版商
  • 免疫印迹; 大鼠
Ye S, Su L, Shan P, Ye B, Wu S, Liang G, et al. LCZ696 Attenuated Doxorubicin-Induced Chronic Cardiomyopathy Through the TLR2-MyD88 Complex Formation. Front Cell Dev Biol. 2021;9:654051 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 图 3d
Petrovic I, Pejnovic N, Ljujic B, Pavlovic S, Miletic Kovacevic M, Jeftic I, et al. Overexpression of Galectin 3 in Pancreatic β Cells Amplifies β-Cell Apoptosis and Islet Inflammation in Type-2 Diabetes in Mice. Front Endocrinol (Lausanne). 2020;11:30 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 3b
Zhang S, Hu L, Jiang J, Li H, Wu Q, Ooi K, et al. HMGB1/RAGE axis mediates stress-induced RVLM neuroinflammation in mice via impairing mitophagy flux in microglia. J Neuroinflammation. 2020;17:15 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:200; 图 3b
Bergqvist F, Carr A, Wheway K, Watkins B, Oppermann U, Jakobsson P, et al. Divergent roles of prostacyclin and PGE2 in human tendinopathy. Arthritis Res Ther. 2019;21:74 pubmed 出版商
  • 免疫印迹; 大鼠; 图 2a
Gasparotto J, Girardi C, Somensi N, Ribeiro C, Moreira J, Michels M, et al. Receptor for advanced glycation end products mediates sepsis-triggered amyloid-β accumulation, Tau phosphorylation, and cognitive impairment. J Biol Chem. 2018;293:226-244 pubmed 出版商
  • 免疫组化; 大鼠; 图 6a
  • 免疫印迹; 大鼠; 图 6g
Shi Y, Zhang X, Chen C, Tang M, Wang Z, Liang X, et al. Schisantherin A attenuates ischemia/reperfusion-induced neuronal injury in rats via regulation of TLR4 and C5aR1 signaling pathways. Brain Behav Immun. 2017;66:244-256 pubmed 出版商
  • 免疫组化-冰冻切片; 大鼠; 1:100; 图 5a
  • 免疫印迹; 大鼠; 1:500; 图 1f
Rong H, Zhao Z, Feng J, Lei Y, Wu H, Sun R, et al. The effects of dexmedetomidine pretreatment on the pro- and anti-inflammation systems after spinal cord injury in rats. Brain Behav Immun. 2017;64:195-207 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:200; 图 1b
Dakin S, Buckley C, Al Mossawi M, Hedley R, Martinez F, Wheway K, et al. Persistent stromal fibroblast activation is present in chronic tendinopathy. Arthritis Res Ther. 2017;19:16 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 2a
Luo L, Bokil N, Wall A, Kapetanovic R, Lansdaal N, Marceline F, et al. SCIMP is a transmembrane non-TIR TLR adaptor that promotes proinflammatory cytokine production from macrophages. Nat Commun. 2017;8:14133 pubmed 出版商
  • 免疫印迹; 大鼠; 1:1000; 图 4b
Sominsky L, Ziko I, Soch A, Smith J, Spencer S. Neonatal overfeeding induces early decline of the ovarian reserve: Implications for the role of leptin. Mol Cell Endocrinol. 2016;431:24-35 pubmed 出版商
  • 免疫印迹; 小鼠; 图 2bb
Li G, Wu X, Yang L, He Y, Liu Y, Jin X, et al. TLR4-mediated NF-κB signaling pathway mediates HMGB1-induced pancreatic injury in mice with severe acute pancreatitis. Int J Mol Med. 2016;37:99-107 pubmed 出版商
  • 免疫组化-石蜡切片; 大鼠; 图 6
Nozako M, Koyama T, Nagano C, Sato M, Matsumoto S, Mitani K, et al. An Atherogenic Paigen-Diet Aggravates Nephropathy in Type 2 Diabetic OLETF Rats. PLoS ONE. 2015;10:e0143979 pubmed 出版商
  • 免疫组化-石蜡切片; 大鼠; 1:100
Wang X, Xiong M, Zeng Y, Sun X, Gong T, Zhang Z. Mechanistic studies of a novel mycophenolic acid-glucosamine conjugate that attenuates renal ischemia/reperfusion injury in rat. Mol Pharm. 2014;11:3503-14 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:200
Weng H, Liu H, Deng Y, Xie Y, Shen G. Effects of high mobility group protein box 1 and toll like receptor 4 pathway on warts caused by human papillomavirus. Mol Med Rep. 2014;10:1765-71 pubmed 出版商
Chen Y, Liu Q, Shan Z, Zhao Y, Li M, Wang B, et al. The protective effect and mechanism of catalpol on high glucose-induced podocyte injury. BMC Complement Altern Med. 2019;19:244 pubmed 出版商
Li N, Xu H, Ou Y, Feng Z, Zhang Q, Zhu Q, et al. LPS-induced CXCR7 expression promotes gastric Cancer proliferation and migration via the TLR4/MD-2 pathway. Diagn Pathol. 2019;14:3 pubmed 出版商
Li J, Moturi K, Wang L, Zhang K, Yu C. Gut derived-endotoxin contributes to inflammation in severe ischemic acute kidney injury. BMC Nephrol. 2019;20:16 pubmed 出版商
Chen Q, Wang M, Shao S, Liu H, Xia X, Tse G, et al. Mechanisms of Intravascular Linear Ablation Induced Restenosis in Rabbit Abdominal Aorta. Biomed Res Int. 2018;2018:7459276 pubmed 出版商
Vincent D, Klinke M, Eschenburg G, Trochimiuk M, Appl B, Tiemann B, et al. NEC is likely a NETs dependent process and markers of NETosis are predictive of NEC in mice and humans. Sci Rep. 2018;8:12612 pubmed 出版商
Krasovska V, Doering L. Regulation of IL-6 Secretion by Astrocytes via TLR4 in the Fragile X Mouse Model. Front Mol Neurosci. 2018;11:272 pubmed 出版商
Shen Y, Qin H, Chen J, Mou L, He Y, Yan Y, et al. Postnatal activation of TLR4 in astrocytes promotes excitatory synaptogenesis in hippocampal neurons. J Cell Biol. 2016;215:719-734 pubmed
Rienks M, Papageorgiou A, Wouters K, Verhesen W, Leeuwen R, Carai P, et al. A novel 72-kDa leukocyte-derived osteoglycin enhances the activation of toll-like receptor 4 and exacerbates cardiac inflammation during viral myocarditis. Cell Mol Life Sci. 2017;74:1511-1525 pubmed 出版商
Liu Y, Li T, Xu Y, Xu E, Zhou M, Wang B, et al. Effects of TLR4 gene silencing on the proliferation and apotosis of hepatocarcinoma HEPG2 cells. Oncol Lett. 2016;11:3054-3060 pubmed
Wu W, Wang F, Gao X, Niu T, Zhu X, Yan X, et al. Synergistic effect of ?-carrageenan on oxazolone-induced inflammation in BALB/c mice. BMC Gastroenterol. 2016;16:41 pubmed 出版商
Guo J, Chen L, Luo N, Li C, Chen R, Qu X, et al. LPS/TLR4-mediated stromal cells acquire an invasive phenotype and are implicated in the pathogenesis of adenomyosis. Sci Rep. 2016;6:21416 pubmed 出版商
Ta M, Liuwantara D, Rangan G. Effects of pyrrolidine dithiocarbamate on proliferation and nuclear factor-κB activity in autosomal dominant polycystic kidney disease cells. BMC Nephrol. 2015;16:212 pubmed 出版商
Chen Y, Huang X, Yu N, Xie Y, Zhang K, Wen F, et al. HMGB1 Contributes to the Expression of P-Glycoprotein in Mouse Epileptic Brain through Toll-Like Receptor 4 and Receptor for Advanced Glycation End Products. PLoS ONE. 2015;10:e0140918 pubmed 出版商
Wang X, Lei F, Du F, Chai Y, Jiang J, Wang Y, et al. Protection of Gastrointestinal Mucosa from Acute Heavy Alcohol Consumption: The Effect of Berberine and Its Correlation with TLR2, 4/IL1β-TNFα Signaling. PLoS ONE. 2015;10:e0134044 pubmed 出版商
Gargus M, Niu C, Vallone J, Binkley J, Rubin D, Shaker A. Human esophageal myofibroblasts secrete proinflammatory cytokines in response to acid and Toll-like receptor 4 ligands. Am J Physiol Gastrointest Liver Physiol. 2015;308:G904-23 pubmed
Dange R, Agarwal D, Teruyama R, Francis J. Toll-like receptor 4 inhibition within the paraventricular nucleus attenuates blood pressure and inflammatory response in a genetic model of hypertension. J Neuroinflammation. 2015;12:31 pubmed 出版商
Masson G, Nair A, Dange R, Silva Soares P, Michelini L, Francis J. Toll-like receptor 4 promotes autonomic dysfunction, inflammation and microglia activation in the hypothalamic paraventricular nucleus: role of endoplasmic reticulum stress. PLoS ONE. 2015;10:e0122850 pubmed 出版商
Stephen G, Lui S, Hamilton S, Tower C, Harris L, Stevens A, et al. Transcriptomic profiling of human choriodecidua during term labor: inflammation as a key driver of labor. Am J Reprod Immunol. 2015;73:36-55 pubmed 出版商
Liu Y, Gao Y, Zhan X, Cui L, Xu S, Ma D, et al. TLR4 activation by lipopolysaccharide and Streptococcus mutans induces differential regulation of proliferation and migration in human dental pulp stem cells. J Endod. 2014;40:1375-81 pubmed 出版商
Qi Y, Zhao M, Bai Y, Huang L, Yu W, Bian Z, et al. Retinal ischemia/reperfusion injury is mediated by Toll-like receptor 4 activation of NLRP3 inflammasomes. Invest Ophthalmol Vis Sci. 2014;55:5466-75 pubmed 出版商
Semba K, Namekata K, Guo X, Harada C, Harada T, Mitamura Y. Renin-angiotensin system regulates neurodegeneration in a mouse model of normal tension glaucoma. Cell Death Dis. 2014;5:e1333 pubmed 出版商
Luo L, Wall A, Yeo J, Condon N, Norwood S, Schoenwaelder S, et al. Rab8a interacts directly with PI3K? to modulate TLR4-driven PI3K and mTOR signalling. Nat Commun. 2014;5:4407 pubmed 出版商
Ingham V, Williams A, Bate C. Glimepiride reduces CD14 expression and cytokine secretion from macrophages. J Neuroinflammation. 2014;11:115 pubmed 出版商
Wang H, Gou S, Zhao M, Chen M. The expression of Toll-like receptors 2, 4 and 9 in kidneys of patients with anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis. Clin Exp Immunol. 2014;177:603-10 pubmed 出版商
Zhu H, Bian C, Yuan J, Chu W, Xiang X, Chen F, et al. Curcumin attenuates acute inflammatory injury by inhibiting the TLR4/MyD88/NF-?B signaling pathway in experimental traumatic brain injury. J Neuroinflammation. 2014;11:59 pubmed 出版商
Khan K, Fujishita A, Kitajima M, Hiraki K, Nakashima M, Masuzaki H. Occult microscopic endometriosis: undetectable by laparoscopy in normal peritoneum. Hum Reprod. 2014;29:462-72 pubmed 出版商
Asgari E, Le Friec G, Yamamoto H, Perucha E, Sacks S, Köhl J, et al. C3a modulates IL-1β secretion in human monocytes by regulating ATP efflux and subsequent NLRP3 inflammasome activation. Blood. 2013;122:3473-81 pubmed 出版商
Weng H, Deng Y, Xie Y, Liu H, Gong F. Expression and significance of HMGB1, TLR4 and NF-?B p65 in human epidermal tumors. BMC Cancer. 2013;13:311 pubmed 出版商
Ehsan N, Murad S, Ashiq T, Mansoor M, Gul S, Khalid S, et al. Significant correlation of TLR4 expression with the clinicopathological features of invasive ductal carcinoma of the breast. Tumour Biol. 2013;34:1053-9 pubmed 出版商
He Z, Wang X, Deng Y, Li W, Chen Y, Xing S, et al. Epigenetic regulation of Thy-1 gene expression by histone modification is involved in lipopolysaccharide-induced lung fibroblast proliferation. J Cell Mol Med. 2013;17:160-7 pubmed 出版商
Zhang Q, Wang C, Han D, Sy C, Huang Q, Sun Y, et al. Differential expression of Toll-like receptor pathway genes in chronic rhinosinusitis with or without nasal polyps. Acta Otolaryngol. 2013;133:165-73 pubmed 出版商
Scarpa M, Cardin R, Bortolami M, Kotsafti A, Scarpa M, Pozza A, et al. Mucosal immune environment in colonic carcinogenesis: CD80 expression is associated to oxidative DNA damage and TLR4-NF?B signalling. Eur J Cancer. 2013;49:254-63 pubmed 出版商
He Z, Gao Y, Deng Y, Li W, Chen Y, Xing S, et al. Lipopolysaccharide induces lung fibroblast proliferation through Toll-like receptor 4 signaling and the phosphoinositide3-kinase-Akt pathway. PLoS ONE. 2012;7:e35926 pubmed 出版商
Xu S, Liu X, Bao Y, Zhu X, Han C, Zhang P, et al. Constitutive MHC class I molecules negatively regulate TLR-triggered inflammatory responses via the Fps-SHP-2 pathway. Nat Immunol. 2012;13:551-9 pubmed 出版商
Xu H, Wu Q, Dang S, Jin M, Xu J, Cheng Y, et al. Alteration of CXCR7 expression mediated by TLR4 promotes tumor cell proliferation and migration in human colorectal carcinoma. PLoS ONE. 2011;6:e27399 pubmed 出版商
Zhan Z, Li Q, Wu P, Ye Y, Tseng H, Zhang L, et al. Autophagy-mediated HMGB1 release antagonizes apoptosis of gastric cancer cells induced by vincristine via transcriptional regulation of Mcl-1. Autophagy. 2012;8:109-21 pubmed 出版商
Youssef Elabd E, McGee K, Tripathi G, Aldaghri N, Abdalla M, Sharada H, et al. Acute and chronic saturated fatty acid treatment as a key instigator of the TLR-mediated inflammatory response in human adipose tissue, in vitro. J Nutr Biochem. 2012;23:39-50 pubmed 出版商
Ghanim H, Sia C, Korzeniewski K, Lohano T, Abuaysheh S, Marumganti A, et al. A resveratrol and polyphenol preparation suppresses oxidative and inflammatory stress response to a high-fat, high-carbohydrate meal. J Clin Endocrinol Metab. 2011;96:1409-14 pubmed 出版商
Ghanim H, Sia C, Upadhyay M, Upadhyay M, Korzeniewski K, Viswanathan P, et al. Orange juice neutralizes the proinflammatory effect of a high-fat, high-carbohydrate meal and prevents endotoxin increase and Toll-like receptor expression. Am J Clin Nutr. 2010;91:940-9 pubmed 出版商
Yamawaki H, Hirohata S, Miyoshi T, Takahashi K, Ogawa H, Shinohata R, et al. Hyaluronan receptors involved in cytokine induction in monocytes. Glycobiology. 2009;19:83-92 pubmed 出版商
Ghanim H, Mohanty P, Deopurkar R, Sia C, Korzeniewski K, Abuaysheh S, et al. Acute modulation of toll-like receptors by insulin. Diabetes Care. 2008;31:1827-31 pubmed 出版商
产品信息
目录号 :
ab22048
ItemName :
抗Toll样受体4抗体[76B357.1]
类别 :
抗体
宿主 :
小鼠
克隆性 :
单克隆
共轭标签 :
未共轭
克隆名称 :
76B357.1
规格 :
100微克
物种摘要 :
Hu, Ms, Pig, Rat
应用摘要 :
ELISA, Flow Cyt, ICC, ICC/IF, IHC-Fr, IHC-P
公司信息
艾博抗(上海)贸易有限公司
上海市浦东新区伽利略路338号5幢4层5401室
cn.technical@abcam.com
http://www.abcam.cn
400-628-6880 86-21-5110 5938
公司总部: 英国
Abcam是全球知名的生命科学研究领域产品提供商,产品涵盖一抗、二抗、蛋白、多肽及ELISA kit。