产品简要
公司名称 :
艾博抗(上海)贸易有限公司
其他品牌 :
Epitomics, Ascent Scientific, MitoSciences
产品类型 :
抗体
产品名称 :
Anti-FOXP3 antibody [mAbcam 22510]
目录 :
ab22510
规格 :
25微克
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
mAbcam 22510
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫组化-石蜡切片, 免疫组化-冰冻切片
文章摘录数: 56
出版应用/物种/样本/稀释参考文献
  • 免疫组化; 人类; 1:50
Brune M, Stussi G, Lundberg P, Vela V, Heim D, Manz M, et al. Effects of lenalidomide on the bone marrow microenvironment in acute myeloid leukemia: Translational analysis of the HOVON103 AML/SAKK30/10 Swiss trial cohort. Ann Hematol. 2021;100:1169-1179 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:50; 图 7a
Hanaoka H, Nishimoto T, Okazaki Y, Takeuchi T, Kuwana M. A unique thymus-derived regulatory T cell subset associated with systemic lupus erythematosus. Arthritis Res Ther. 2020;22:88 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 表 1
Zheng C, Zheng L, Yoo J, Guo H, Zhang Y, Guo X, et al. Landscape of Infiltrating T Cells in Liver Cancer Revealed by Single-Cell Sequencing. Cell. 2017;169:1342-1356.e16 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 17.0 ug/ml; 图 1F
Ameratunga M, Asadi K, Lin X, Walkiewicz M, Murone C, Knight S, et al. PD-L1 and Tumor Infiltrating Lymphocytes as Prognostic Markers in Resected NSCLC. PLoS ONE. 2016;11:e0153954 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 20 ug/ml; 图 3b
  • 免疫印迹; 人类; 图 3f
Gao Y, Zhang M, Li J, Yang M, Liu Y, Guo X, et al. Circulating FoxP3+ Regulatory T and Interleukin17-Producing Th17 Cells Actively Influence HBV Clearance in De Novo Hepatitis B Virus Infected Patients after Orthotopic Liver Transplantation. PLoS ONE. 2015;10:e0137881 pubmed 出版商
  • 免疫印迹; 人类; 图 1a
Zhang X, Gao L, Liang X, Guo M, Wang R, Pan Y, et al. HBV preS2 transactivates FOXP3 expression in malignant hepatocytes. Liver Int. 2015;35:1087-94 pubmed 出版商
Qiu Q, Yu X, Yao C, Hao Y, Fan L, Li C, et al. FOXP3 pathogenic variants cause male infertility through affecting the proliferation and apoptosis of human spermatogonial stem cells. Aging (Albany NY). 2019;11:12581-12599 pubmed 出版商
Sun W, Wei F, Li W, Wei J, Zhong H, Wen Y, et al. A positive-feedback loop between tumour infiltrating activated Treg cells and type 2-skewed macrophages is essential for progression of laryngeal squamous cell carcinoma. Br J Cancer. 2017;117:1631-1643 pubmed 出版商
Zhang X, Yamaoka K, Sonomoto K, Kaneko H, Satake M, Yamamoto Y, et al. Local delivery of mesenchymal stem cells with poly-lactic-co-glycolic acid nano-fiber scaffold suppress arthritis in rats. PLoS ONE. 2014;9:e114621 pubmed 出版商
Magni S, Buoli Comani G, Elli L, Vanessi S, Ballarini E, Nicolini G, et al. miRNAs affect the expression of innate and adaptive immunity proteins in celiac disease. Am J Gastroenterol. 2014;109:1662-74 pubmed 出版商
Tong C, Jia X, Jia Y, He Y. Langerhans cell histiocytosis in Chinese adults: absence of BRAF mutations and increased FOXP3(+) regulatory T cells. Int J Clin Exp Pathol. 2014;7:3166-73 pubmed
Zhuo C, Li Z, Xu Y, Wang Y, Li Q, Peng J, et al. Higher FOXP3-TSDR demethylation rates in adjacent normal tissues in patients with colon cancer were associated with worse survival. Mol Cancer. 2014;13:153 pubmed 出版商
Takenaka M, Seki N, Toh U, Hattori S, Kawahara A, Yamaguchi T, et al. FOXP3 expression in tumor cells and tumor-infiltrating lymphocytes is associated with breast cancer prognosis. Mol Clin Oncol. 2013;1:625-632 pubmed
Tarhini A, Edington H, Butterfield L, Lin Y, Shuai Y, Tawbi H, et al. Immune monitoring of the circulation and the tumor microenvironment in patients with regionally advanced melanoma receiving neoadjuvant ipilimumab. PLoS ONE. 2014;9:e87705 pubmed 出版商
Cho Y, Lin J, Chen Y, Chang C, Hsiao C, Chung W, et al. Generalized bullous fixed drug eruption is distinct from Stevens-Johnson syndrome/toxic epidermal necrolysis by immunohistopathological features. J Am Acad Dermatol. 2014;70:539-48 pubmed 出版商
Li J, Wang F, She W, Yang C, Li L, Tu C, et al. Enhanced high-mobility group box 1 (HMGB1) modulates regulatory T cells (Treg)/T helper 17 (Th17) balance via toll-like receptor (TLR)-4-interleukin (IL)-6 pathway in patients with chronic hepatitis B. J Viral Hepat. 2014;21:129-40 pubmed 出版商
Migita K, Sho M, Shimada K, Yasuda S, Yamato I, Takayama T, et al. Significant involvement of herpesvirus entry mediator in human esophageal squamous cell carcinoma. Cancer. 2014;120:808-17 pubmed 出版商
Li W, Wang L, Jiang C, Li H, Zhang K, Xu Y, et al. UXT is a novel regulatory factor of regulatory T cells associated with Foxp3. Eur J Immunol. 2014;44:533-44 pubmed 出版商
Ugolini C, Elisei R, Proietti A, Pelliccioni S, Lupi C, Borrelli N, et al. FoxP3 expression in papillary thyroid carcinoma: a possible resistance biomarker to iodine 131 treatment. Thyroid. 2014;24:339-46 pubmed 出版商
Germanidis G, Argentou N, Hytiroglou P, Vassiliadis T, Patsiaoura K, Germenis A, et al. Liver FOXP3 and PD1/PDL1 Expression is Down-Regulated in Chronic HBV Hepatitis on Maintained Remission Related to the Degree of Inflammation. Front Immunol. 2013;4:207 pubmed 出版商
Droeser R, Obermann E, Wolf A, Wallner S, Wolf D, Tzankov A. Negligible nuclear FOXP3 expression in breast cancer epithelial cells compared with FOXP3-positive T cells. Clin Breast Cancer. 2013;13:264-70 pubmed 出版商
Vasilescu F, Arsene D, Cionca F, Comănescu M, Enache V, Iosif C, et al. Foxp3 and IL17 expression in tumor infiltrating lymphocytes (TIL) and tumor cells - correlated or independent factors?. Rom J Morphol Embryol. 2013;54:43-9 pubmed
Yamasaki S, Miyagi Maeshima A, Kakugawa Y, Matsuno Y, Ohara Waki F, Fuji S, et al. Diagnosis and evaluation of intestinal graft-versus-host disease after allogeneic hematopoietic stem cell transplantation following reduced-intensity and myeloablative conditioning regimens. Int J Hematol. 2013;97:421-6 pubmed 出版商
Kim M, Grimmig T, Grimm M, Lazariotou M, Meier E, Rosenwald A, et al. Expression of Foxp3 in colorectal cancer but not in Treg cells correlates with disease progression in patients with colorectal cancer. PLoS ONE. 2013;8:e53630 pubmed 出版商
Maehara T, Moriyama M, Hayashida J, Tanaka A, Shinozaki S, Kubo Y, et al. Selective localization of T helper subsets in labial salivary glands from primary Sjögren's syndrome patients. Clin Exp Immunol. 2012;169:89-99 pubmed 出版商
Yang J, Zhang J, Wang H, Wang G, Hu Q, Zheng Q. Hepatocellular carcinoma and macrophage interaction induced tumor immunosuppression via Treg requires TLR4 signaling. World J Gastroenterol. 2012;18:2938-47 pubmed 出版商
Löfdahl B, Ahlin C, Holmqvist M, Holmberg L, Zhou W, Fjällskog M, et al. Inflammatory cells in node-negative breast cancer. Acta Oncol. 2012;51:680-6 pubmed 出版商
Yuan Y, Ren J, Cao S, Zhang W, Li J. Exogenous C3 protein enhances the adaptive immune response to polymicrobial sepsis through down-regulation of regulatory T cells. Int Immunopharmacol. 2012;12:271-7 pubmed 出版商
Sterlacci W, Wolf D, Savic S, Hilbe W, Schmid T, Jamnig H, et al. High transforming growth factor ? expression represents an important prognostic parameter for surgically resected non-small cell lung cancer. Hum Pathol. 2012;43:339-49 pubmed 出版商
Speletas M, Argentou N, Germanidis G, Vasiliadis T, Mantzoukis K, Patsiaoura K, et al. Foxp3 expression in liver correlates with the degree but not the cause of inflammation. Mediators Inflamm. 2011;2011:827565 pubmed 出版商
Engelmann P, Farkas K, Kis J, Richman G, Zhang Z, Liew C, et al. Characterization of human invariant natural killer T cells expressing FoxP3. Int Immunol. 2011;23:473-84 pubmed 出版商
Sundin M, D Arcy P, Johansson C, Barrett A, Lönnies H, Sundberg B, et al. Multipotent mesenchymal stromal cells express FoxP3: a marker for the immunosuppressive capacity?. J Immunother. 2011;34:336-42 pubmed 出版商
Mansfield A, Holtan S, Grotz T, Allred J, Jakub J, Erickson L, et al. Regional immunity in melanoma: immunosuppressive changes precede nodal metastasis. Mod Pathol. 2011;24:487-94 pubmed 出版商
Ferri S, Longhi M, De Molo C, Lalanne C, Muratori P, Granito A, et al. A multifaceted imbalance of T cells with regulatory function characterizes type 1 autoimmune hepatitis. Hepatology. 2010;52:999-1007 pubmed 出版商
Minoo P, Zlobec I, Peterson M, Terracciano L, Lugli A. Characterization of rectal, proximal and distal colon cancers based on clinicopathological, molecular and protein profiles. Int J Oncol. 2010;37:707-18 pubmed
Matsumoto Y, Horiike S, Ohshiro M, Yamamoto M, Sasaki N, Tsutsumi Y, et al. Expression of master regulators of helper T-cell differentiation in peripheral T-cell lymphoma, not otherwise specified, by immunohistochemical analysis. Am J Clin Pathol. 2010;133:281-90 pubmed 出版商
Sweetenham J, Goldman B, LeBlanc M, Cook J, Tubbs R, Press O, et al. Prognostic value of regulatory T cells, lymphoma-associated macrophages, and MUM-1 expression in follicular lymphoma treated before and after the introduction of monoclonal antibody therapy: a Southwest Oncology Group Study. Ann Oncol. 2010;21:1196-202 pubmed 出版商
Richendollar B, Tsao R, Elson P, Jin T, Steinle R, Pohlman B, et al. Predictors of outcome in post-transplant lymphoproliferative disorder: an evaluation of tumor infiltrating lymphocytes in the context of clinical factors. Leuk Lymphoma. 2009;50:2005-12 pubmed 出版商
Heinze E, Baldwin S, Chan G, Hansen J, Song J, Clements D, et al. Antibody-mediated FOXP3 protein therapy induces apoptosis in cancer cells in vitro and inhibits metastasis in vivo. Int J Oncol. 2009;35:167-73 pubmed
Jang T. Prevalence of Foxp3 positive T regulatory cells is increased during progression of cutaneous squamous tumors. Yonsei Med J. 2008;49:942-8 pubmed 出版商
Li Y, Zhao X, Cheng D, Haga H, Tsuruyama T, Wood K, et al. The presence of Foxp3 expressing T cells within grafts of tolerant human liver transplant recipients. Transplantation. 2008;86:1837-43 pubmed 出版商
Kotakadi V, Jin Y, Hofseth A, Ying L, Cui X, Volate S, et al. Ginkgo biloba extract EGb 761 has anti-inflammatory properties and ameliorates colitis in mice by driving effector T cell apoptosis. Carcinogenesis. 2008;29:1799-806 pubmed 出版商
Bunnag S, Allanach K, Jhangri G, Sis B, Einecke G, Mengel M, et al. FOXP3 expression in human kidney transplant biopsies is associated with rejection and time post transplant but not with favorable outcomes. Am J Transplant. 2008;8:1423-33 pubmed 出版商
Woo Y, Sterling J, Crawford R, van der Burg S, Coleman N, Stanley M. FOXP3 immunohistochemistry on formalin-fixed paraffin-embedded tissue: poor correlation between different antibodies. J Clin Pathol. 2008;61:969-71 pubmed 出版商
Anraku M, Cunningham K, Yun Z, Tsao M, Zhang L, Keshavjee S, et al. Impact of tumor-infiltrating T cells on survival in patients with malignant pleural mesothelioma. J Thorac Cardiovasc Surg. 2008;135:823-9 pubmed 出版商
Tzankov A, Meier C, Hirschmann P, Went P, Pileri S, Dirnhofer S. Correlation of high numbers of intratumoral FOXP3+ regulatory T cells with improved survival in germinal center-like diffuse large B-cell lymphoma, follicular lymphoma and classical Hodgkin's lymphoma. Haematologica. 2008;93:193-200 pubmed 出版商
Sakaki M, Hiroishi K, Baba T, Ito T, Hirayama Y, Saito K, et al. Intrahepatic status of regulatory T cells in autoimmune liver diseases and chronic viral hepatitis. Hepatol Res. 2008;38:354-61 pubmed
Yang Z, Novak A, Ziesmer S, Witzig T, Ansell S. CD70+ non-Hodgkin lymphoma B cells induce Foxp3 expression and regulatory function in intratumoral CD4+CD25 T cells. Blood. 2007;110:2537-44 pubmed
Polak M, Borthwick N, Gabriel F, Johnson P, Higgins B, Hurren J, et al. Mechanisms of local immunosuppression in cutaneous melanoma. Br J Cancer. 2007;96:1879-87 pubmed
Eijkelkamp N, Heijnen C, Lucas A, Premont R, Elsenbruch S, Schedlowski M, et al. G protein-coupled receptor kinase 6 controls chronicity and severity of dextran sodium sulphate-induced colitis in mice. Gut. 2007;56:847-54 pubmed
Sasaki M, Ikeda H, Sawada S, Sato Y, Nakanuma Y. Naturally-occurring regulatory T cells are increased in inflamed portal tracts with cholangiopathy in primary biliary cirrhosis. J Clin Pathol. 2007;60:1102-7 pubmed
Petersen R, Campa M, Sperlazza J, Conlon D, Joshi M, Harpole D, et al. Tumor infiltrating Foxp3+ regulatory T-cells are associated with recurrence in pathologic stage I NSCLC patients. Cancer. 2006;107:2866-72 pubmed
Mahic M, Yaqub S, Johansson C, Tasken K, Aandahl E. FOXP3+CD4+CD25+ adaptive regulatory T cells express cyclooxygenase-2 and suppress effector T cells by a prostaglandin E2-dependent mechanism. J Immunol. 2006;177:246-54 pubmed
Oh U, Grant C, Griffith C, Fugo K, Takenouchi N, Jacobson S. Reduced Foxp3 protein expression is associated with inflammatory disease during human t lymphotropic virus type 1 Infection. J Infect Dis. 2006;193:1557-66 pubmed
Grant C, Oh U, Fugo K, Takenouchi N, Griffith C, Yao K, et al. Foxp3 represses retroviral transcription by targeting both NF-kappaB and CREB pathways. PLoS Pathog. 2006;2:e33 pubmed
Veldman C, Pahl A, Beissert S, Hansen W, Buer J, Dieckmann D, et al. Inhibition of the transcription factor Foxp3 converts desmoglein 3-specific type 1 regulatory T cells into Th2-like cells. J Immunol. 2006;176:3215-22 pubmed
产品信息
目录号 :
ab22510
ItemName :
Anti-FOXP3 antibody [mAbcam 22510]
产品类型 :
一抗
宿主物种 :
小鼠
克隆性 :
单克隆
共轭标签 :
Not Conjugated
抗原修饰 :
No Modifications
克隆名称 :
mAbcam 22510
规格 :
25微克
物种摘要 :
Hu, Rat
用途 :
ICC/IF, IHC-Fr, IHC-P, WB
规格说明 :
Other sizes available: 100 µg,100 µl,200 µg,200 µl
公司信息
艾博抗(上海)贸易有限公司
上海市浦东新区伽利略路338号5幢4层5401室
cn.technical@abcam.com
http://www.abcam.cn
400-628-6880 86-21-5110 5938
公司总部: 英国
Abcam是全球知名的生命科学研究领域产品提供商,产品涵盖一抗、二抗、蛋白、多肽及ELISA kit。