产品简要
公司名称 :
艾博抗(上海)贸易有限公司
其他品牌 :
Epitomics, Ascent Scientific, MitoSciences
产品类型 :
抗体
产品名称 :
抗FOXA1抗体-ChIP级
目录 :
ab23738
规格 :
100微克
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 免疫组化, EMSA, 染色质免疫沉淀 , 免疫组化-石蜡切片, ChIP-Seq
文章摘录数: 25
出版应用/物种/样本/稀释参考文献
  • 免疫组化-石蜡切片; 小鼠; 1:250; 图 4s1a
van Veen J, Scherzer M, Boshuizen J, Chu M, Liu A, Landman A, et al. Mutationally-activated PI3'-kinase-α promotes de-differentiation of lung tumors initiated by the BRAFV600E oncoprotein kinase. elife. 2019;8: pubmed 出版商
  • 免疫组化; 大鼠; 1:200; 图 3d
Ding L, Shunkwiler L, Harper N, Zhao Y, Hinohara K, Huh S, et al. Deletion of Cdkn1b in ACI rats leads to increased proliferation and pregnancy-associated changes in the mammary gland due to perturbed systemic endocrine environment. PLoS Genet. 2019;15:e1008002 pubmed 出版商
  • 染色质免疫沉淀 ; 人类; 图 3k
  • 免疫印迹; 人类; 1:1000; 图 4e
Harrod A, Fulton J, Nguyen V, Periyasamy M, Ramos Garcia L, Lai C, et al. Genomic modelling of the ESR1 Y537S mutation for evaluating function and new therapeutic approaches for metastatic breast cancer. Oncogene. 2017;36:2286-2296 pubmed 出版商
  • 免疫组化; 人类; 图 s3
Hatem R, El Botty R, Chateau Joubert S, Servely J, Labiod D, de Plater L, et al. Targeting mTOR pathway inhibits tumor growth in different molecular subtypes of triple-negative breast cancers. Oncotarget. 2016;7:48206-48219 pubmed 出版商
  • 免疫组化; 人类; 1:500
  • 免疫印迹; 人类
Varešlija D, McBryan J, Fagan A, Redmond A, Hao Y, Sims A, et al. Adaptation to AI Therapy in Breast Cancer Can Induce Dynamic Alterations in ER Activity Resulting in Estrogen-Independent Metastatic Tumors. Clin Cancer Res. 2016;22:2765-77 pubmed 出版商
  • ChIP-Seq; 人类; 图 1
  • 免疫印迹; 人类; 图 4
Zhao J, Fong K, Jin H, Yang Y, Kim J, Yu J. FOXA1 acts upstream of GATA2 and AR in hormonal regulation of gene expression. Oncogene. 2016;35:4335-44 pubmed 出版商
Wang Y, Zhang L, Wei N, Sun Y, Pan W, Chen Y. Silencing LINC00482 inhibits tumor-associated inflammation and angiogenesis through down-regulation of MMP-15 via FOXA1 in bladder cancer. Aging (Albany NY). 2020;13:2264-2278 pubmed 出版商
Zhang Y, Chan H, Garcia Martinez L, Karl D, Weich N, Slingerland J, et al. Estrogen induces dynamic ERα and RING1B recruitment to control gene and enhancer activities in luminal breast cancer. Sci Adv. 2020;6:eaaz7249 pubmed 出版商
Zhou S, Hawley J, Soares F, Grillo G, Teng M, Madani Tonekaboni S, et al. Noncoding mutations target cis-regulatory elements of the FOXA1 plexus in prostate cancer. Nat Commun. 2020;11:441 pubmed 出版商
Mazrooei P, Kron K, Zhu Y, Zhou S, Grillo G, Mehdi T, et al. Cistrome Partitioning Reveals Convergence of Somatic Mutations and Risk Variants on Master Transcription Regulators in Primary Prostate Tumors. Cancer Cell. 2019;36:674-689.e6 pubmed 出版商
Yuan F, Hankey W, Wu D, Wang H, Somarelli J, Armstrong A, et al. Molecular determinants for enzalutamide-induced transcription in prostate cancer. Nucleic Acids Res. 2019;47:10104-10114 pubmed 出版商
Parolia A, Cieslik M, Chu S, Xiao L, Ouchi T, Zhang Y, et al. Distinct structural classes of activating FOXA1 alterations in advanced prostate cancer. Nature. 2019;: pubmed 出版商
Cato L, De Tribolet Hardy J, Lee I, Rottenberg J, Coleman I, Melchers D, et al. ARv7 Represses Tumor-Suppressor Genes in Castration-Resistant Prostate Cancer. Cancer Cell. 2019;35:401-413.e6 pubmed 出版商
Song B, Park S, Zhao J, Fong K, Li S, Lee Y, et al. Targeting FOXA1-mediated repression of TGF-β signaling suppresses castration-resistant prostate cancer progression. J Clin Invest. 2019;129:569-582 pubmed 出版商
Michalak E, Milevskiy M, Joyce R, Dekkers J, Jamieson P, Pal B, et al. Canonical PRC2 function is essential for mammary gland development and affects chromatin compaction in mammary organoids. PLoS Biol. 2018;16:e2004986 pubmed 出版商
Takeda D, Spisak S, Seo J, Bell C, O CONNOR E, Korthauer K, et al. A Somatically Acquired Enhancer of the Androgen Receptor Is a Noncoding Driver in Advanced Prostate Cancer. Cell. 2018;174:422-432.e13 pubmed 出版商
Martin L, Ribas R, Simigdala N, Schuster E, Pancholi S, Tenev T, et al. Discovery of naturally occurring ESR1 mutations in breast cancer cell lines modelling endocrine resistance. Nat Commun. 2017;8:1865 pubmed 出版商
Whirledge S, Kisanga E, Taylor R, Cidlowski J. Pioneer Factors FOXA1 and FOXA2 Assist Selective Glucocorticoid Receptor Signaling in Human Endometrial Cells. Endocrinology. 2017;158:4076-4092 pubmed 出版商
Malinen M, Niskanen E, Kaikkonen M, Palvimo J. Crosstalk between androgen and pro-inflammatory signaling remodels androgen receptor and NF-?B cistrome to reprogram the prostate cancer cell transcriptome. Nucleic Acids Res. 2017;45:619-630 pubmed 出版商
Xu Y, Qin L, Sun T, Wu H, He T, Yang Z, et al. Twist1 promotes breast cancer invasion and metastasis by silencing Foxa1 expression. Oncogene. 2017;36:1157-1166 pubmed 出版商
Jin H, Jung S, DebRoy A, Davuluri R. Identification and validation of regulatory SNPs that modulate transcription factor chromatin binding and gene expression in prostate cancer. Oncotarget. 2016;7:54616-54626 pubmed 出版商
Yang Y, Zhao J, Fong K, Kim J, Li S, Song C, et al. FOXA1 potentiates lineage-specific enhancer activation through modulating TET1 expression and function. Nucleic Acids Res. 2016;44:8153-64 pubmed 出版商
Heckman M, Robinson J, Tzou K, Parker A, Wu K, Hilton T, et al. An Examination of the Association between FOXA1 Staining Level and Biochemical Recurrence following Salvage Radiation Therapy for Recurrent Prostate Cancer. PLoS ONE. 2016;11:e0151785 pubmed 出版商
Sunkel B, Wu D, Chen Z, Wang C, Liu X, Ye Z, et al. Integrative analysis identifies targetable CREB1/FoxA1 transcriptional co-regulation as a predictor of prostate cancer recurrence. Nucleic Acids Res. 2016;44:4105-22 pubmed 出版商
Grabowska M, Kelly S, Reese A, Cates J, Case T, Zhang J, et al. Nfib Regulates Transcriptional Networks That Control the Development of Prostatic Hyperplasia. Endocrinology. 2016;157:1094-109 pubmed 出版商
产品信息
目录号 :
ab23738
ItemName :
抗FOXA1抗体-ChIP级
产品类型 :
一抗
宿主物种 :
克隆性 :
多克隆
共轭标签 :
Not Conjugated
抗原修饰 :
No Modifications
规格 :
100微克
物种摘要 :
Hu, Ms
用途 :
ChIP, ChIP/Chip, EMSA, WB
规格说明 :
Other sizes available: 100 µl,200 µl
公司信息
艾博抗(上海)贸易有限公司
上海市浦东新区伽利略路338号5幢4层5401室
cn.technical@abcam.com
http://www.abcam.cn
400-628-6880 86-21-5110 5938
公司总部: 英国
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