产品简要
公司名称 :
艾博抗(上海)贸易有限公司
其他品牌 :
Epitomics, Ascent Scientific, MitoSciences
产品类型 :
抗体
产品名称 :
抗溶酶体相关膜蛋白质1抗体[1D4B]
目录 :
ab25245
规格 :
100微克
克隆性 :
单克隆
宿主 :
大鼠
共轭标签 :
未共轭
克隆名称 :
1D4B
反应物种 :
人类, 小鼠
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀, 流式细胞仪, 免疫组化-石蜡切片, 免疫组化-冰冻切片, 其他
文章摘录数: 29
出版应用/物种/样本/稀释参考文献
  • 免疫组化; 小鼠; 1:500; 图 5d
Glajch K, Moors T, Chen Y, Bechade P, Nam A, Rajsombath M, et al. Wild-type GBA1 increases the α-synuclein tetramer-monomer ratio, reduces lipid-rich aggregates, and attenuates motor and cognitive deficits in mice. Proc Natl Acad Sci U S A. 2021;118: pubmed 出版商
  • 免疫组化; 小鼠; 1:500; 图 6g
  • 免疫印迹; 小鼠; 1:500; 图 6c
Takahashi K, Nakamura S, Otsu W, Shimazawa M, Hara H. Progranulin deficiency in Iba-1+ myeloid cells exacerbates choroidal neovascularization by perturbation of lysosomal function and abnormal inflammation. J Neuroinflammation. 2021;18:164 pubmed 出版商
  • 免疫组化; 小鼠; 1:200; 图 3h
Claes C, Danhash E, Hasselmann J, Chadarevian J, Shabestari S, England W, et al. Plaque-associated human microglia accumulate lipid droplets in a chimeric model of Alzheimer's disease. Mol Neurodegener. 2021;16:50 pubmed 出版商
  • 免疫细胞化学; 小鼠; 1:300
Birsa N, Ule A, Garone M, Tsang B, Mattedi F, Chong P, et al. FUS-ALS mutants alter FMRP phase separation equilibrium and impair protein translation. Sci Adv. 2021;7: pubmed 出版商
  • 免疫细胞化学; 人类; 图 1d
Nakatani T, Tsujimoto K, Park J, Jo T, Kimura T, Hayama Y, et al. The lysosomal Ragulator complex plays an essential role in leukocyte trafficking by activating myosin II. Nat Commun. 2021;12:3333 pubmed 出版商
  • 免疫组化; 人类; 1:100
Xu J, Wang Y, Hsu C, Negri S, Tower R, Gao Y, et al. Lysosomal protein surface expression discriminates fat- from bone-forming human mesenchymal precursor cells. elife. 2020;9: pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1:500; 图 6h
Cignarella F, Filipello F, Bollman B, Cantoni C, Locca A, Mikesell R, et al. TREM2 activation on microglia promotes myelin debris clearance and remyelination in a model of multiple sclerosis. Acta Neuropathol. 2020;140:513-534 pubmed 出版商
  • 免疫组化; 小鼠; 1:2000; 图 7a
Meilandt W, Ngu H, Gogineni A, Lalehzadeh G, Lee S, Srinivasan K, et al. Trem2 Deletion Reduces Late-Stage Amyloid Plaque Accumulation, Elevates the Aβ42:Aβ40 Ratio, and Exacerbates Axonal Dystrophy and Dendritic Spine Loss in the PS2APP Alzheimer's Mouse Model. J Neurosci. 2020;40:1956-1974 pubmed 出版商
  • 免疫细胞化学; 人类; 图 2d
Stévenin V, Chang Y, Le Toquin Y, Duchateau M, Gianetto Q, Luk C, et al. Dynamic Growth and Shrinkage of the Salmonella-Containing Vacuole Determines the Intracellular Pathogen Niche. Cell Rep. 2019;29:3958-3973.e7 pubmed 出版商
  • 免疫细胞化学; 小鼠; 图 3b
  • 免疫印迹; 小鼠; 图 4a
Ho P, Leung C, Liu H, Pang S, Lam C, Xian J, et al. Age-dependent accumulation of oligomeric SNCA/α-synuclein from impaired degradation in mutant LRRK2 knockin mouse model of Parkinson disease: role for therapeutic activation of chaperone-mediated autophagy (CMA). Autophagy. 2019;:1-24 pubmed 出版商
  • 免疫细胞化学; 小鼠; 图 3a
Losier T, Akuma M, McKee Muir O, LeBlond N, Suk Y, Alsaadi R, et al. AMPK Promotes Xenophagy through Priming of Autophagic Kinases upon Detection of Bacterial Outer Membrane Vesicles. Cell Rep. 2019;26:2150-2165.e5 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1:200; 图 6a
Pellegrini L, Hauser D, Li Y, Mamais A, Beilina A, Kumaran R, et al. Proteomic analysis reveals co-ordinated alterations in protein synthesis and degradation pathways in LRRK2 knockout mice. Hum Mol Genet. 2018;27:3257-3271 pubmed 出版商
  • 免疫组化; 人类; 1:1000; 图 8a
Lagrange B, Benaoudia S, Wallet P, Magnotti F, Provost A, Michal F, et al. Human caspase-4 detects tetra-acylated LPS and cytosolic Francisella and functions differently from murine caspase-11. Nat Commun. 2018;9:242 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 3e
Shroff A, Sequeira R, Patel V, Reddy K. Knockout of autophagy gene, ATG5 in mice vaginal cells abrogates cytokine response and pathogen clearance during vaginal infection of Candida albicans. Cell Immunol. 2018;324:59-73 pubmed 出版商
  • 免疫印迹; 小鼠; 图 s1c
Gao Y, Chen Y, Zhan S, Zhang W, Xiong F, Ge W. Comprehensive proteome analysis of lysosomes reveals the diverse function of macrophages in immune responses. Oncotarget. 2017;8:7420-7440 pubmed 出版商
  • 免疫组化; 小鼠; 图 7a
Da Ros M, Lehtiniemi T, Olotu O, Fischer D, Zhang F, Vihinen H, et al. FYCO1 and autophagy control the integrity of the haploid male germ cell-specific RNP granules. Autophagy. 2017;13:302-321 pubmed 出版商
  • 免疫细胞化学; 小鼠
  • 免疫细胞化学; 人类
Nakamura T, Furukawa A, Uchida K, Ogawa T, Tamura T, Sakonishi D, et al. Autophagy Induced by Intracellular Infection of Propionibacterium acnes. PLoS ONE. 2016;11:e0156298 pubmed 出版商
  • 免疫细胞化学; 人类; 1:300; 图 1
Pawar K, Sharbati J, Einspanier R, Sharbati S. Mycobacterium bovis BCG Interferes with miR-3619-5p Control of Cathepsin S in the Process of Autophagy. Front Cell Infect Microbiol. 2016;6:27 pubmed 出版商
  • 免疫印迹; 小鼠; 1:2000; 图 7a
Son S, Cha M, Choi H, Kang S, Choi H, Lee M, et al. Insulin-degrading enzyme secretion from astrocytes is mediated by an autophagy-based unconventional secretory pathway in Alzheimer disease. Autophagy. 2016;12:784-800 pubmed 出版商
  • 免疫印迹; 人类; 1:5000; 图 3b
O Donovan T, Rajendran S, O Reilly S, O Sullivan G, McKenna S. Lithium Modulates Autophagy in Esophageal and Colorectal Cancer Cells and Enhances the Efficacy of Therapeutic Agents In Vitro and In Vivo. PLoS ONE. 2015;10:e0134676 pubmed 出版商
Blazquez C, Ruiz Calvo A, Bajo Grañeras R, Baufreton J, Resel E, Varilh M, et al. Inhibition of striatonigral autophagy as a link between cannabinoid intoxication and impairment of motor coordination. elife. 2020;9: pubmed 出版商
Martin S, Smolders S, Van den Haute C, Heeman B, van Veen S, Crosiers D, et al. Mutated ATP10B increases Parkinson's disease risk by compromising lysosomal glucosylceramide export. Acta Neuropathol. 2020;139:1001-1024 pubmed 出版商
Pei D, Sun J, Zhu C, Tian F, Jiao K, Anderson M, et al. Contribution of Mitophagy to Cell-Mediated Mineralization: Revisiting a 50-Year-Old Conundrum. Adv Sci (Weinh). 2018;5:1800873 pubmed 出版商
Emperador Melero J, Huson V, Van Weering J, Bollmann C, Fischer von Mollard G, Toonen R, et al. Vti1a/b regulate synaptic vesicle and dense core vesicle secretion via protein sorting at the Golgi. Nat Commun. 2018;9:3421 pubmed 出版商
Lundquist M, Goncalves M, Loughran R, Possik E, Vijayaraghavan T, Yang A, et al. Phosphatidylinositol-5-Phosphate 4-Kinases Regulate Cellular Lipid Metabolism By Facilitating Autophagy. Mol Cell. 2018;70:531-544.e9 pubmed 出版商
Beckel J, Gómez N, Lu W, Campagno K, Nabet B, Albalawi F, et al. Stimulation of TLR3 triggers release of lysosomal ATP in astrocytes and epithelial cells that requires TRPML1 channels. Sci Rep. 2018;8:5726 pubmed 出版商
Chen D, Xie J, Fiskesund R, Dong W, Liang X, Lv J, et al. Chloroquine modulates antitumor immune response by resetting tumor-associated macrophages toward M1 phenotype. Nat Commun. 2018;9:873 pubmed 出版商
Sahu S, Kumar M, Chakraborty S, Banerjee S, Kumar R, Gupta P, et al. MicroRNA 26a (miR-26a)/KLF4 and CREB-C/EBPβ regulate innate immune signaling, the polarization of macrophages and the trafficking of Mycobacterium tuberculosis to lysosomes during infection. PLoS Pathog. 2017;13:e1006410 pubmed 出版商
Chen X, Clark J, Wunderlich M, Fan C, Davis A, Chen S, et al. Autophagy is dispensable for Kmt2a/Mll-Mllt3/Af9 AML maintenance and anti-leukemic effect of chloroquine. Autophagy. 2017;13:955-966 pubmed 出版商
产品信息
目录号 :
ab25245
ItemName :
抗溶酶体相关膜蛋白质1抗体[1D4B]
产品类型 :
一抗
宿主物种 :
大鼠
克隆性 :
单克隆
共轭标签 :
Not Conjugated
抗原修饰 :
No Modifications
克隆名称 :
1D4B
规格 :
100微克
物种摘要 :
Hu, Ms
用途 :
Flow Cyt, ICC/IF, IHC-Fr, IHC-P, IM, IP, Other, WB
公司信息
艾博抗(上海)贸易有限公司
上海市浦东新区伽利略路338号5幢4层5401室
cn.technical@abcam.com
http://www.abcam.cn
400-628-6880 86-21-5110 5938
公司总部: 英国
Abcam是全球知名的生命科学研究领域产品提供商,产品涵盖一抗、二抗、蛋白、多肽及ELISA kit。