产品简要
公司名称 :
艾博抗(上海)贸易有限公司
其他品牌 :
Epitomics, Ascent Scientific, MitoSciences
产品类型 :
抗体
产品名称 :
抗Gli2抗体-ChIP级
目录 :
ab26056
规格 :
100微升
克隆性 :
多克隆
宿主 :
共轭标签 :
未共轭
反应物种 :
人类, 小鼠, 果蝇
应用 :
免疫印迹, 免疫细胞化学, 免疫沉淀, EMSA, 染色质免疫沉淀 , 免疫组化-石蜡切片
文章摘录数: 40
出版应用/物种/样本/稀释参考文献
  • 染色质免疫沉淀 ; 人类; 图 5
  • 免疫印迹; 人类; 图 s5
Vlčková K, OndruÅ¡ová L, Vachtenheim J, Réda J, Dundr P, Zadinová M, et al. Survivin, a novel target of the Hedgehog/GLI signaling pathway in human tumor cells. Cell Death Dis. 2016;7:e2048 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:100
Pan Y, Gong Y, Ruan H, Pan L, Wu X, Tang C, et al. Sonic hedgehog through Gli2 and Gli3 is required for the proper development of placental labyrinth. Cell Death Dis. 2015;6:e1653 pubmed 出版商
  • 免疫印迹; 人类; 图 5
Tang C, Pan Y, Luo H, Xiong W, Zhu H, Ruan H, et al. Hedgehog signaling stimulates the conversion of cholesterol to steroids. Cell Signal. 2015;27:487-97 pubmed 出版商
  • 免疫细胞化学; 小鼠; 1:100
Liu J, Bain L. Arsenic inhibits hedgehog signaling during P19 cell differentiation. Toxicol Appl Pharmacol. 2014;281:243-53 pubmed 出版商
  • 免疫沉淀; 人类; 图 3
  • 免疫印迹; 人类; 图 2
Xing Z, Lin A, Li C, Liang K, Wang S, Liu Y, et al. lncRNA directs cooperative epigenetic regulation downstream of chemokine signals. Cell. 2014;159:1110-1125 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 2
  • 免疫印迹; 人类; 1:1000; 图 2
He P, Staufenbiel M, Li R, Shen Y. Deficiency of patched 1-induced Gli1 signal transduction results in astrogenesis in Swedish mutated APP transgenic mice. Hum Mol Genet. 2014;23:6512-27 pubmed 出版商
  • 免疫印迹; 果蝇
Shahi M, Holt R, Rebhun R. Blocking signaling at the level of GLI regulates downstream gene expression and inhibits proliferation of canine osteosarcoma cells. PLoS ONE. 2014;9:e96593 pubmed 出版商
  • 免疫印迹; 人类
Matsumoto T, Tabata K, Suzuki T. The GANT61, a GLI inhibitor, induces caspase-independent apoptosis of SK-N-LO cells. Biol Pharm Bull. 2014;37:633-41 pubmed
  • 免疫印迹; 小鼠; 1:1000
Romani S, Illi B, De Mori R, Savino M, Gleeson J, Valente E. The ciliary proteins Meckelin and Jouberin are required for retinoic acid-dependent neural differentiation of mouse embryonic stem cells. Differentiation. 2014;87:134-146 pubmed 出版商
  • 免疫细胞化学; 人类
  • 免疫印迹; 人类
Chen Q, Xu R, Zeng C, Lu Q, Huang D, Shi C, et al. Down-regulation of Gli transcription factor leads to the inhibition of migration and invasion of ovarian cancer cells via integrin ?4-mediated FAK signaling. PLoS ONE. 2014;9:e88386 pubmed 出版商
  • 免疫细胞化学; 小鼠; 1:200
Li Y, Drnevich J, Akraiko T, Band M, Li D, Wang F, et al. Gene expression profiling reveals the heterogeneous transcriptional activity of Oct3/4 and its possible interaction with Gli2 in mouse embryonic stem cells. Genomics. 2013;102:456-67 pubmed 出版商
  • 免疫细胞化学; 人类; 1:200
Bosco Clément G, Zhang F, Chen Z, Zhou H, Li H, Mikami I, et al. Targeting Gli transcription activation by small molecule suppresses tumor growth. Oncogene. 2014;33:2087-97 pubmed 出版商
  • 免疫组化-石蜡切片; 人类
Cigna N, Farrokhi Moshai E, Brayer S, Marchal Sommé J, Wemeau Stervinou L, Fabre A, et al. The hedgehog system machinery controls transforming growth factor-?-dependent myofibroblastic differentiation in humans: involvement in idiopathic pulmonary fibrosis. Am J Pathol. 2012;181:2126-37 pubmed 出版商
Xu C, Zou C, Hussain M, Shi W, Shao Y, Jiang Z, et al. High expression of Sonic hedgehog in allergic airway epithelia contributes to goblet cell metaplasia. Mucosal Immunol. 2018;11:1306-1315 pubmed 出版商
Li Q, Alsaidan O, Rai S, Wu M, Shen H, Beharry Z, et al. Stromal Gli signaling regulates the activity and differentiation of prostate stem and progenitor cells. J Biol Chem. 2018;293:10547-10560 pubmed 出版商
Zheng X, Han H, Liu G, Ma Y, Pan R, Sang L, et al. LncRNA wires up Hippo and Hedgehog signaling to reprogramme glucose metabolism. EMBO J. 2017;36:3325-3335 pubmed 出版商
Phua S, Chiba S, Suzuki M, Su E, Roberson E, Pusapati G, et al. Dynamic Remodeling of Membrane Composition Drives Cell Cycle through Primary Cilia Excision. Cell. 2017;168:264-279.e15 pubmed 出版商
Lin Z, Li S, Sheng H, Cai M, Ma L, Hu L, et al. Suppression of GLI sensitizes medulloblastoma cells to mitochondria-mediated apoptosis. J Cancer Res Clin Oncol. 2016;142:2469-2478 pubmed
Li J, Wang Q, Cui Y, Yang X, Li Y, Zhang X, et al. Suppressor of Fused Is Required for Determining Digit Number and Identity via Gli3/Fgfs/Gremlin. PLoS ONE. 2015;10:e0128006 pubmed 出版商
Zeng C, Wang Y, Lu Q, Chen J, Zhang J, Liu T, et al. SPOP suppresses tumorigenesis by regulating Hedgehog/Gli2 signaling pathway in gastric cancer. J Exp Clin Cancer Res. 2014;33:75 pubmed 出版商
Jäger W, Thomas C, Fazli L, Hurtado Coll A, Li E, Janssen C, et al. DHH is an independent prognosticator of oncologic outcome of clear cell renal cell carcinoma. J Urol. 2014;192:1842-8 pubmed 出版商
García Zaragoza E, Pérez Tavarez R, Ballester A, Lafarga V, Jiménez Reinoso A, Ramirez A, et al. Intraepithelial paracrine Hedgehog signaling induces the expansion of ciliated cells that express diverse progenitor cell markers in the basal epithelium of the mouse mammary gland. Dev Biol. 2012;372:28-44 pubmed 出版商
Alexandrescu S, Tatevian N, Czerniak B, Covinsky M, Burns N, Brown R. Morphoproteomics provides support for TGF-? pathway signaling in the osteoclastogenesis and immune dysregulation of osteolytic Langerhans cell histiocytosis. Int J Clin Exp Pathol. 2012;5:503-11 pubmed
Alexandrescu S, Brown R, Tandon N, Bhattacharjee M. Neuron precursor features of spindle cell oncocytoma of adenohypophysis. Ann Clin Lab Sci. 2012;42:123-9 pubmed
Yang L, Wang L, Chen X, Gatalica Z, Qiu S, Liu Z, et al. Hedgehog signaling activation in the development of squamous cell carcinoma and adenocarcinoma of esophagus. Int J Biochem Mol Biol. 2012;3:46-57 pubmed
Jung I, Jung D, Park Y, Song S, Park S. Aberrant Hedgehog ligands induce progressive pancreatic fibrosis by paracrine activation of myofibroblasts and ductular cells in transgenic zebrafish. PLoS ONE. 2011;6:e27941 pubmed 出版商
Buczkowicz P, Ma J, Hawkins C. GLI2 is a potential therapeutic target in pediatric medulloblastoma. J Neuropathol Exp Neurol. 2011;70:430-7 pubmed 出版商
Malek R, Matta J, Taylor N, Perry M, Mendrysa S. The p53 inhibitor MDM2 facilitates Sonic Hedgehog-mediated tumorigenesis and influences cerebellar foliation. PLoS ONE. 2011;6:e17884 pubmed 出版商
Coon V, Laukert T, Pedone C, Laterra J, Kim K, Fults D. Molecular therapy targeting Sonic hedgehog and hepatocyte growth factor signaling in a mouse model of medulloblastoma. Mol Cancer Ther. 2010;9:2627-36 pubmed 出版商
Peacock Z, Cox D, Schmidt B. Involvement of PTCH1 mutations in the calcifying epithelial odontogenic tumor. Oral Oncol. 2010;46:387-92 pubmed 出版商
Youssef K, Van Keymeulen A, Lapouge G, Beck B, Michaux C, Achouri Y, et al. Identification of the cell lineage at the origin of basal cell carcinoma. Nat Cell Biol. 2010;12:299-305 pubmed 出版商
Nakamura K, Sasajima J, Mizukami Y, Sugiyama Y, Yamazaki M, Fujii R, et al. Hedgehog promotes neovascularization in pancreatic cancers by regulating Ang-1 and IGF-1 expression in bone-marrow derived pro-angiogenic cells. PLoS ONE. 2010;5:e8824 pubmed 出版商
Kim W, Wang X, Wu Y, Doble B, Patel S, Woodgett J, et al. GSK-3 is a master regulator of neural progenitor homeostasis. Nat Neurosci. 2009;12:1390-7 pubmed 出版商
Ho L, Stojanovski A, Whetstone H, Wei Q, Mau E, Wunder J, et al. Gli2 and p53 cooperate to regulate IGFBP-3- mediated chondrocyte apoptosis in the progression from benign to malignant cartilage tumors. Cancer Cell. 2009;16:126-36 pubmed 出版商
Kim J, Singh R, Cho Vega J, Drakos E, Davuluri Y, Khokhar F, et al. Sonic hedgehog signaling proteins and ATP-binding cassette G2 are aberrantly expressed in diffuse large B-cell lymphoma. Mod Pathol. 2009;22:1312-20 pubmed 出版商
Syn W, Witek R, Curbishley S, Jung Y, Choi S, Enrich B, et al. Role for hedgehog pathway in regulating growth and function of invariant NKT cells. Eur J Immunol. 2009;39:1879-92 pubmed 出版商
Gialmanidis I, Bravou V, Amanetopoulou S, Varakis J, Kourea H, Papadaki H. Overexpression of hedgehog pathway molecules and FOXM1 in non-small cell lung carcinomas. Lung Cancer. 2009;66:64-74 pubmed 出版商
Wall D, Mears A, McNeill B, Mazerolle C, Thurig S, Wang Y, et al. Progenitor cell proliferation in the retina is dependent on Notch-independent Sonic hedgehog/Hes1 activity. J Cell Biol. 2009;184:101-12 pubmed 出版商
Madison B, McKenna L, Dolson D, Epstein D, Kaestner K. FoxF1 and FoxL1 link hedgehog signaling and the control of epithelial proliferation in the developing stomach and intestine. J Biol Chem. 2009;284:5936-44 pubmed 出版商
Takanaga H, Tsuchida Straeten N, Nishide K, Watanabe A, Aburatani H, Kondo T. Gli2 is a novel regulator of sox2 expression in telencephalic neuroepithelial cells. Stem Cells. 2009;27:165-74 pubmed 出版商
产品信息
目录号 :
ab26056
ItemName :
抗Gli2抗体-ChIP级
类别 :
抗体
宿主 :
克隆性 :
多克隆
共轭标签 :
未共轭
规格 :
100微升
物种摘要 :
Hu
应用摘要 :
ChIP, EMSA, 免疫细胞化学, 免疫细胞化学/IF, 免疫印迹
公司信息
艾博抗(上海)贸易有限公司
上海市浦东新区伽利略路338号5幢4层5401室
cn.technical@abcam.com
http://www.abcam.cn
400-628-6880 86-21-5110 5938
公司总部: 英国
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