出版应用/物种/样本/稀释 | 参考文献 |
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- 染色质免疫沉淀
; 人类; 图 5
- 免疫印迹; 人类; 图 s5
| VlÄková K, OndruÅ¡ová L, Vachtenheim J, Réda J, Dundr P, Zadinová M, et al. Survivin, a novel target of the Hedgehog/GLI signaling pathway in human tumor cells. Cell Death Dis. 2016;7:e2048 pubmed 出版商
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| Pan Y, Gong Y, Ruan H, Pan L, Wu X, Tang C, et al. Sonic hedgehog through Gli2 and Gli3 is required for the proper development of placental labyrinth. Cell Death Dis. 2015;6:e1653 pubmed 出版商
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| Tang C, Pan Y, Luo H, Xiong W, Zhu H, Ruan H, et al. Hedgehog signaling stimulates the conversion of cholesterol to steroids. Cell Signal. 2015;27:487-97 pubmed 出版商
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| Liu J, Bain L. Arsenic inhibits hedgehog signaling during P19 cell differentiation. Toxicol Appl Pharmacol. 2014;281:243-53 pubmed 出版商
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- 免疫沉淀; 人类; 图 3
- 免疫印迹; 人类; 图 2
| Xing Z, Lin A, Li C, Liang K, Wang S, Liu Y, et al. lncRNA directs cooperative epigenetic regulation downstream of chemokine signals. Cell. 2014;159:1110-1125 pubmed 出版商
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- 免疫印迹; 小鼠; 1:1000; 图 2
- 免疫印迹; 人类; 1:1000; 图 2
| He P, Staufenbiel M, Li R, Shen Y. Deficiency of patched 1-induced Gli1 signal transduction results in astrogenesis in Swedish mutated APP transgenic mice. Hum Mol Genet. 2014;23:6512-27 pubmed 出版商
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| Shahi M, Holt R, Rebhun R. Blocking signaling at the level of GLI regulates downstream gene expression and inhibits proliferation of canine osteosarcoma cells. PLoS ONE. 2014;9:e96593 pubmed 出版商
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| Matsumoto T, Tabata K, Suzuki T. The GANT61, a GLI inhibitor, induces caspase-independent apoptosis of SK-N-LO cells. Biol Pharm Bull. 2014;37:633-41 pubmed
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| Romani S, Illi B, De Mori R, Savino M, Gleeson J, Valente E. The ciliary proteins Meckelin and Jouberin are required for retinoic acid-dependent neural differentiation of mouse embryonic stem cells. Differentiation. 2014;87:134-146 pubmed 出版商
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| Chen Q, Xu R, Zeng C, Lu Q, Huang D, Shi C, et al. Down-regulation of Gli transcription factor leads to the inhibition of migration and invasion of ovarian cancer cells via integrin ?4-mediated FAK signaling. PLoS ONE. 2014;9:e88386 pubmed 出版商
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| Li Y, Drnevich J, Akraiko T, Band M, Li D, Wang F, et al. Gene expression profiling reveals the heterogeneous transcriptional activity of Oct3/4 and its possible interaction with Gli2 in mouse embryonic stem cells. Genomics. 2013;102:456-67 pubmed 出版商
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| Bosco Clément G, Zhang F, Chen Z, Zhou H, Li H, Mikami I, et al. Targeting Gli transcription activation by small molecule suppresses tumor growth. Oncogene. 2014;33:2087-97 pubmed 出版商
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| Cigna N, Farrokhi Moshai E, Brayer S, Marchal Sommé J, Wemeau Stervinou L, Fabre A, et al. The hedgehog system machinery controls transforming growth factor-?-dependent myofibroblastic differentiation in humans: involvement in idiopathic pulmonary fibrosis. Am J Pathol. 2012;181:2126-37 pubmed 出版商
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| Xu C, Zou C, Hussain M, Shi W, Shao Y, Jiang Z, et al. High expression of Sonic hedgehog in allergic airway epithelia contributes to goblet cell metaplasia. Mucosal Immunol. 2018;11:1306-1315 pubmed 出版商
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| Li Q, Alsaidan O, Rai S, Wu M, Shen H, Beharry Z, et al. Stromal Gli signaling regulates the activity and differentiation of prostate stem and progenitor cells. J Biol Chem. 2018;293:10547-10560 pubmed 出版商
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| Zheng X, Han H, Liu G, Ma Y, Pan R, Sang L, et al. LncRNA wires up Hippo and Hedgehog signaling to reprogramme glucose metabolism. EMBO J. 2017;36:3325-3335 pubmed 出版商
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| Phua S, Chiba S, Suzuki M, Su E, Roberson E, Pusapati G, et al. Dynamic Remodeling of Membrane Composition Drives Cell Cycle through Primary Cilia Excision. Cell. 2017;168:264-279.e15 pubmed 出版商
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| Lin Z, Li S, Sheng H, Cai M, Ma L, Hu L, et al. Suppression of GLI sensitizes medulloblastoma cells to mitochondria-mediated apoptosis. J Cancer Res Clin Oncol. 2016;142:2469-2478 pubmed
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| Li J, Wang Q, Cui Y, Yang X, Li Y, Zhang X, et al. Suppressor of Fused Is Required for Determining Digit Number and Identity via Gli3/Fgfs/Gremlin. PLoS ONE. 2015;10:e0128006 pubmed 出版商
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| Zeng C, Wang Y, Lu Q, Chen J, Zhang J, Liu T, et al. SPOP suppresses tumorigenesis by regulating Hedgehog/Gli2 signaling pathway in gastric cancer. J Exp Clin Cancer Res. 2014;33:75 pubmed 出版商
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| Jäger W, Thomas C, Fazli L, Hurtado Coll A, Li E, Janssen C, et al. DHH is an independent prognosticator of oncologic outcome of clear cell renal cell carcinoma. J Urol. 2014;192:1842-8 pubmed 出版商
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| García Zaragoza E, Pérez Tavarez R, Ballester A, Lafarga V, Jiménez Reinoso A, Ramirez A, et al. Intraepithelial paracrine Hedgehog signaling induces the expansion of ciliated cells that express diverse progenitor cell markers in the basal epithelium of the mouse mammary gland. Dev Biol. 2012;372:28-44 pubmed 出版商
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| Alexandrescu S, Tatevian N, Czerniak B, Covinsky M, Burns N, Brown R. Morphoproteomics provides support for TGF-? pathway signaling in the osteoclastogenesis and immune dysregulation of osteolytic Langerhans cell histiocytosis. Int J Clin Exp Pathol. 2012;5:503-11 pubmed
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| Alexandrescu S, Brown R, Tandon N, Bhattacharjee M. Neuron precursor features of spindle cell oncocytoma of adenohypophysis. Ann Clin Lab Sci. 2012;42:123-9 pubmed
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| Yang L, Wang L, Chen X, Gatalica Z, Qiu S, Liu Z, et al. Hedgehog signaling activation in the development of squamous cell carcinoma and adenocarcinoma of esophagus. Int J Biochem Mol Biol. 2012;3:46-57 pubmed
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| Jung I, Jung D, Park Y, Song S, Park S. Aberrant Hedgehog ligands induce progressive pancreatic fibrosis by paracrine activation of myofibroblasts and ductular cells in transgenic zebrafish. PLoS ONE. 2011;6:e27941 pubmed 出版商
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| Buczkowicz P, Ma J, Hawkins C. GLI2 is a potential therapeutic target in pediatric medulloblastoma. J Neuropathol Exp Neurol. 2011;70:430-7 pubmed 出版商
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| Malek R, Matta J, Taylor N, Perry M, Mendrysa S. The p53 inhibitor MDM2 facilitates Sonic Hedgehog-mediated tumorigenesis and influences cerebellar foliation. PLoS ONE. 2011;6:e17884 pubmed 出版商
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| Coon V, Laukert T, Pedone C, Laterra J, Kim K, Fults D. Molecular therapy targeting Sonic hedgehog and hepatocyte growth factor signaling in a mouse model of medulloblastoma. Mol Cancer Ther. 2010;9:2627-36 pubmed 出版商
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| Peacock Z, Cox D, Schmidt B. Involvement of PTCH1 mutations in the calcifying epithelial odontogenic tumor. Oral Oncol. 2010;46:387-92 pubmed 出版商
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| Youssef K, Van Keymeulen A, Lapouge G, Beck B, Michaux C, Achouri Y, et al. Identification of the cell lineage at the origin of basal cell carcinoma. Nat Cell Biol. 2010;12:299-305 pubmed 出版商
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| Nakamura K, Sasajima J, Mizukami Y, Sugiyama Y, Yamazaki M, Fujii R, et al. Hedgehog promotes neovascularization in pancreatic cancers by regulating Ang-1 and IGF-1 expression in bone-marrow derived pro-angiogenic cells. PLoS ONE. 2010;5:e8824 pubmed 出版商
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| Kim W, Wang X, Wu Y, Doble B, Patel S, Woodgett J, et al. GSK-3 is a master regulator of neural progenitor homeostasis. Nat Neurosci. 2009;12:1390-7 pubmed 出版商
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| Ho L, Stojanovski A, Whetstone H, Wei Q, Mau E, Wunder J, et al. Gli2 and p53 cooperate to regulate IGFBP-3- mediated chondrocyte apoptosis in the progression from benign to malignant cartilage tumors. Cancer Cell. 2009;16:126-36 pubmed 出版商
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| Kim J, Singh R, Cho Vega J, Drakos E, Davuluri Y, Khokhar F, et al. Sonic hedgehog signaling proteins and ATP-binding cassette G2 are aberrantly expressed in diffuse large B-cell lymphoma. Mod Pathol. 2009;22:1312-20 pubmed 出版商
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| Syn W, Witek R, Curbishley S, Jung Y, Choi S, Enrich B, et al. Role for hedgehog pathway in regulating growth and function of invariant NKT cells. Eur J Immunol. 2009;39:1879-92 pubmed 出版商
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| Gialmanidis I, Bravou V, Amanetopoulou S, Varakis J, Kourea H, Papadaki H. Overexpression of hedgehog pathway molecules and FOXM1 in non-small cell lung carcinomas. Lung Cancer. 2009;66:64-74 pubmed 出版商
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| Wall D, Mears A, McNeill B, Mazerolle C, Thurig S, Wang Y, et al. Progenitor cell proliferation in the retina is dependent on Notch-independent Sonic hedgehog/Hes1 activity. J Cell Biol. 2009;184:101-12 pubmed 出版商
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| Madison B, McKenna L, Dolson D, Epstein D, Kaestner K. FoxF1 and FoxL1 link hedgehog signaling and the control of epithelial proliferation in the developing stomach and intestine. J Biol Chem. 2009;284:5936-44 pubmed 出版商
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| Takanaga H, Tsuchida Straeten N, Nishide K, Watanabe A, Aburatani H, Kondo T. Gli2 is a novel regulator of sox2 expression in telencephalic neuroepithelial cells. Stem Cells. 2009;27:165-74 pubmed 出版商
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