产品简要
公司名称 :
艾博抗(上海)贸易有限公司
其他品牌 :
Epitomics, Ascent Scientific, MitoSciences
产品类型 :
抗体
产品名称 :
抗丙H2A.X(磷酸化S139)抗体[9F3]
目录 :
ab26350
规格 :
100微克
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
抗原修饰 :
磷酸化
克隆名称 :
9F3
反应物种 :
人类, 小鼠, 大鼠, , , , 猕猴
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀, 流式细胞仪, 免疫组化-石蜡切片, 免疫组化-冰冻切片
文章摘录数: 57
出版应用/物种/样本/稀释参考文献
  • 免疫组化; 小鼠; 1:200; 图 2a
  • 免疫细胞化学; 人类; 1:1000; 图 3d
  • 免疫组化; 人类; 1:200; 图 1a
  • 免疫印迹; 人类; 图 3c
Cao C, Tian B, Geng X, Zhou H, Xu Z, Lai T, et al. IL-17-Mediated Inflammation Promotes Cigarette Smoke-Induced Genomic Instability. Cells. 2021;10: pubmed 出版商
  • 免疫细胞化学; 人类; 图 6g
Kildey K, Gandhi N, Sahin K, Shah E, Boittier E, Duijf P, et al. Elevating CDCA3 levels in non-small cell lung cancer enhances sensitivity to platinum-based chemotherapy. Commun Biol. 2021;4:638 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 s6a
  • 免疫印迹; 小鼠; 1:1000; 图 7a
Pramanick A, Chakraborti S, Mahata T, Basak M, Das K, Verma S, et al. G protein β5-ATM complexes drive acetaminophen-induced hepatotoxicity. Redox Biol. 2021;43:101965 pubmed 出版商
  • 免疫细胞化学; 人类; 1:250; 图 2a
  • 免疫组化; 人类; 图 5c, 5d
Zhu X, Chen L, Huang B, Li X, Yang L, Hu X, et al. Efficacy and mechanism of the combination of PARP and CDK4/6 inhibitors in the treatment of triple-negative breast cancer. J Exp Clin Cancer Res. 2021;40:122 pubmed 出版商
  • 免疫印迹; 人类; 1:500; 图 2g
He S, Ma X, Zheng N, Wang G, Wang M, Xia W, et al. PRDM14 mediates chemosensitivity and glycolysis in drug‑resistant A549/cisplatin cells and their progenitor A549 human lung adenocarcinoma cells. Mol Med Rep. 2021;23: pubmed 出版商
  • 免疫组化; 人类; 图 1c
Fu E, Liu T, Yu S, Chen X, Song L, Lou H, et al. M2 macrophages reduce the radiosensitivity of head and neck cancer by releasing HB‑EGF. Oncol Rep. 2020;44:698-710 pubmed 出版商
  • 免疫细胞化学; 小鼠; 图 7a
Jansons J, Bayurova E, Skrastina D, Kurlanda A, Fridrihsone I, Kostyushev D, et al. Expression of the Reverse Transcriptase Domain of Telomerase Reverse Transcriptase Induces Lytic Cellular Response in DNA-Immunized Mice and Limits Tumorigenic and Metastatic Potential of Murine Adenocarcinoma 4T1 Cells. Vaccines (Basel). 2020;8: pubmed 出版商
  • 免疫印迹; 小鼠; 图 3e
Hastings J, González Rajal A, Latham S, Han J, McCloy R, O Donnell Y, et al. Analysis of pulsed cisplatin signalling dynamics identifies effectors of resistance in lung adenocarcinoma. elife. 2020;9: pubmed 出版商
  • 免疫细胞化学; 小鼠; 图 s8c
  • 免疫印迹; 小鼠; 1:5000; 图 s8a
Ma H, Qian W, Bambousková M, Collins P, Porter S, Byrum A, et al. Barrier-to-Autointegration Factor 1 Protects against a Basal cGAS-STING Response. MBio. 2020;11: pubmed 出版商
  • 免疫细胞化学; 人类; 1:500; 图 3b
Liu H, Liu Y, Yang F, Zhang L, Zhang F, Hu X, et al. Acetylation of MORC2 by NAT10 regulates cell-cycle checkpoint control and resistance to DNA-damaging chemotherapy and radiotherapy in breast cancer. Nucleic Acids Res. 2020;48:3638-3656 pubmed 出版商
  • 免疫细胞化学; 人类; 1:500-1:1000; 图 6c
  • 免疫印迹; 人类; 1:500-1:2000; 图 6a
Wall C, Rose C, Adrian M, Zeng Y, Kirkpatrick D, Bingol B. PPEF2 Opposes PINK1-Mediated Mitochondrial Quality Control by Dephosphorylating Ubiquitin. Cell Rep. 2019;29:3280-3292.e7 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 图 2c
  • 免疫细胞化学; 小鼠; 图 2f
Varuzhanyan G, Rojansky R, Sweredoski M, Graham R, Hess S, Ladinsky M, et al. Mitochondrial fusion is required for spermatogonial differentiation and meiosis. elife. 2019;8: pubmed 出版商
  • 免疫细胞化学; 大鼠; 1:500; 图 3a
Moreno Blas D, Gorostieta Salas E, Pommer Alba A, Muciño Hernández G, Gerónimo Olvera C, Maciel Barón L, et al. Cortical neurons develop a senescence-like phenotype promoted by dysfunctional autophagy. Aging (Albany NY). 2019;11:6175-6198 pubmed 出版商
  • 免疫细胞化学; 小鼠; 1:1000; 图 7s1b
  • 免疫组化; 小鼠; 1:1000; 图 7a
Jia Z, Nie Y, Yue F, Kong Y, Gu L, Gavin T, et al. A requirement of Polo-like kinase 1 in murine embryonic myogenesis and adult muscle regeneration. elife. 2019;8: pubmed 出版商
  • 免疫细胞化学; 小鼠; 1:500; 图 4c
Walton C, Zhang W, Patiño Parrado I, Barrio Alonso E, Garrido J, Frade J. Primary neurons can enter M-phase. Sci Rep. 2019;9:4594 pubmed 出版商
  • 免疫组化; 小鼠; 1:100; 图 6a
Bartova E, Lochmanová G, Legartova S, Suchankova J, Fedr R, Krejci J, et al. Irradiation by γ-rays reduces the level of H3S10 phosphorylation and weakens the G2 phase-dependent interaction between H3S10 phosphorylation and γH2AX. Biochimie. 2018;154:86-98 pubmed 出版商
  • 免疫细胞化学; 小鼠; 图 6e
  • 免疫细胞化学; 人类; 图 2a, 4f
Kannan A, Bhatia K, Branzei D, Gangwani L. Combined deficiency of Senataxin and DNA-PKcs causes DNA damage accumulation and neurodegeneration in spinal muscular atrophy. Nucleic Acids Res. 2018;46:8326-8346 pubmed 出版商
  • 免疫细胞化学; 人类; 图 1a
Xiang Y, Laurent B, Hsu C, Nachtergaele S, Lu Z, Sheng W, et al. RNA m6A methylation regulates the ultraviolet-induced DNA damage response. Nature. 2017;543:573-576 pubmed 出版商
  • 免疫细胞化学; 小鼠; 1:500; 图 5a
Song X, Narzt M, Nagelreiter I, Hohensinner P, Terlecki Zaniewicz L, Tschachler E, et al. Autophagy deficient keratinocytes display increased DNA damage, senescence and aberrant lipid composition after oxidative stress in vitro and in vivo. Redox Biol. 2017;11:219-230 pubmed 出版商
  • 免疫细胞化学; 人类; 图 s20
Hu M, Chen S, Wang B, Ou T, Gu L, Tan J, et al. Specific targeting of telomeric multimeric G-quadruplexes by a new triaryl-substituted imidazole. Nucleic Acids Res. 2017;45:1606-1618 pubmed 出版商
  • 免疫印迹; 犬; 1:5000; 图 4
York D, Withers S, Watson K, Seo K, Rebhun R. Enrofloxacin enhances the effects of chemotherapy in canine osteosarcoma cells with mutant and wild-type p53. Vet Comp Oncol. 2017;15:1087-1100 pubmed 出版商
  • 免疫细胞化学; 人类; 图 1b
  • 免疫印迹; 人类; 图 1a
Yang Q, Pan Q, Li C, Xu Y, Wen C, Sun F. NRAGE is involved in homologous recombination repair to resist the DNA-damaging chemotherapy and composes a ternary complex with RNF8-BARD1 to promote cell survival in squamous esophageal tumorigenesis. Cell Death Differ. 2016;23:1406-16 pubmed 出版商
  • 免疫细胞化学; 人类; 图 3
Bunch H, Lawney B, Lin Y, Asaithamby A, Murshid A, Wang Y, et al. Transcriptional elongation requires DNA break-induced signalling. Nat Commun. 2015;6:10191 pubmed 出版商
  • 免疫细胞化学; 小鼠; 1:400
Ouyang S, Song Y, Tian Y, Chen Y, Yu X, Wang D. RNF8 deficiency results in neurodegeneration in mice. Neurobiol Aging. 2015;36:2850-2860 pubmed 出版商
  • 免疫细胞化学; 犬; 1:500; 图 6
  • 免疫印迹; 犬; 1:1000; 图 5
Nadeau M, Rico C, Tsoi M, Vivancos M, Filimon S, Paquet M, et al. Pharmacological targeting of valosin containing protein (VCP) induces DNA damage and selectively kills canine lymphoma cells. BMC Cancer. 2015;15:479 pubmed 出版商
  • 免疫细胞化学; 人类; 1:100; 图 s1
Yang K, Kohler R, Landon M, Giedt R, Weissleder R. Single cell resolution in vivo imaging of DNA damage following PARP inhibition. Sci Rep. 2015;5:10129 pubmed 出版商
  • 免疫组化-石蜡切片; 大鼠; 1:100
Huang S, Cui Y, Guo X, Wang L, Li S, Lu Y, et al. 2,2',4,4'-Tetrabromodiphenyl ether disrupts spermatogenesis, impairs mitochondrial function and induces apoptosis of early leptotene spermatocytes in rats. Reprod Toxicol. 2015;51:114-24 pubmed 出版商
  • 免疫组化-石蜡切片; 猕猴; 1:250; 图 3a
Mohan M, Kumar V, Lackner A, Alvarez X. Dysregulated miR-34a-SIRT1-acetyl p65 axis is a potential mediator of immune activation in the colon during chronic simian immunodeficiency virus infection of rhesus macaques. J Immunol. 2015;194:291-306 pubmed 出版商
  • 免疫印迹; 犬
Flassig R, Maubach G, Täger C, Sundmacher K, Naumann M. Experimental design, validation and computational modeling uncover DNA damage sensing by DNA-PK and ATM. Mol Biosyst. 2014;10:1978-86 pubmed 出版商
  • 免疫细胞化学; 小鼠; 1:100
Sutherland J, Fraser B, Sobinoff A, Pye V, Davidson T, Siddall N, et al. Developmental expression of Musashi-1 and Musashi-2 RNA-binding proteins during spermatogenesis: analysis of the deleterious effects of dysregulated expression. Biol Reprod. 2014;90:92 pubmed 出版商
  • 免疫组化; 小鼠; 1:200
Di Giacomo M, Comazzetto S, Saini H, De Fazio S, Carrieri C, Morgan M, et al. Multiple epigenetic mechanisms and the piRNA pathway enforce LINE1 silencing during adult spermatogenesis. Mol Cell. 2013;50:601-8 pubmed 出版商
  • 免疫组化-冰冻切片; 鸡; 1:500
He B, Mi Y, Zhang C. Gonadotropins regulate ovarian germ cell mitosis/meiosis decision in the embryonic chicken. Mol Cell Endocrinol. 2013;370:32-41 pubmed 出版商
Zhu C, Li K, Jiang M, Chen S. RBM5-AS1 promotes radioresistance in medulloblastoma through stabilization of SIRT6 protein. Acta Neuropathol Commun. 2021;9:123 pubmed 出版商
Levone B, Lenzken S, Antonaci M, Maiser A, Rapp A, Conte F, et al. FUS-dependent liquid-liquid phase separation is important for DNA repair initiation. J Cell Biol. 2021;220: pubmed 出版商
Zhang W, Cheng W, Parlato R, Guo X, Cui X, Dai C, et al. Nucleolar stress induces a senescence-like phenotype in smooth muscle cells and promotes development of vascular degeneration. Aging (Albany NY). 2020;12:22174-22198 pubmed 出版商
Di Luigi L, Duranti G, Antonioni A, Sgrò P, Ceci R, Crescioli C, et al. The Phosphodiesterase Type 5 Inhibitor Sildenafil Improves DNA Stability and Redox Homeostasis in Systemic Sclerosis Fibroblasts Exposed to Reactive Oxygen Species. Antioxidants (Basel). 2020;9: pubmed 出版商
Xia R, Chen J, Gao J, Luo X, Ke C, Ren C, et al. Inhibition of esophageal-carcinoma cell proliferation by genistein via suppression of JAK1/2-STAT3 and AKT/MDM2/p53 signaling pathways. Aging (Albany NY). 2020;12:6240-6259 pubmed 出版商
Hua R, Wei H, Liu C, Zhang Y, Liu S, Guo Y, et al. FBXO47 regulates telomere-inner nuclear envelope integration by stabilizing TRF2 during meiosis. Nucleic Acids Res. 2019;47:11755-11770 pubmed 出版商
Kostyusheva A, Brezgin S, Bayurova E, Gordeychuk I, Isaguliants M, Goptar I, et al. ATM and ATR Expression Potentiates HBV Replication and Contributes to Reactivation of HBV Infection upon DNA Damage. Viruses. 2019;11: pubmed 出版商
Nagarajan P, Agudelo Garcia P, Iyer C, Popova L, Arnold W, Parthun M. Early-onset aging and mitochondrial defects associated with loss of histone acetyltransferase 1 (Hat1). Aging Cell. 2019;18:e12992 pubmed 出版商
Tian H, Billings T, Petkov P. CXXC1 is not essential for normal DNA double-strand break formation and meiotic recombination in mouse. PLoS Genet. 2018;14:e1007657 pubmed 出版商
Findlay S, Heath J, Luo V, Malina A, Morin T, Coulombe Y, et al. SHLD2/FAM35A co-operates with REV7 to coordinate DNA double-strand break repair pathway choice. EMBO J. 2018;37: pubmed 出版商
Zhai Q, Ge W, Wang J, Sun X, Ma J, Liu J, et al. Exposure to Zinc oxide nanoparticles during pregnancy induces oocyte DNA damage and affects ovarian reserve of mouse offspring. Aging (Albany NY). 2018;10:2170-2189 pubmed 出版商
Latorre E, Torregrossa R, Wood M, Whiteman M, Harries L. Mitochondria-targeted hydrogen sulfide attenuates endothelial senescence by selective induction of splicing factors HNRNPD and SRSF2. Aging (Albany NY). 2018;10:1666-1681 pubmed 出版商
Caridi C, D Agostino C, Ryu T, Zapotoczny G, Delabaere L, Li X, et al. Nuclear F-actin and myosins drive relocalization of heterochromatic breaks. Nature. 2018;559:54-60 pubmed 出版商
Xie Q, Li C, Song X, Wu L, Jiang Q, Qiu Z, et al. Folate deficiency facilitates recruitment of upstream binding factor to hot spots of DNA double-strand breaks of rRNA genes and promotes its transcription. Nucleic Acids Res. 2017;45:2472-2489 pubmed 出版商
McAndrew E, Lepage C, McManus K. The synthetic lethal killing of RAD54B-deficient colorectal cancer cells by PARP1 inhibition is enhanced with SOD1 inhibition. Oncotarget. 2016;7:87417-87430 pubmed 出版商
Much C, Auchynnikava T, Pavlinić D, Buness A, Rappsilber J, Benes V, et al. Endogenous Mouse Dicer Is an Exclusively Cytoplasmic Protein. PLoS Genet. 2016;12:e1006095 pubmed 出版商
Suetens A, Konings K, Moreels M, Quintens R, Verslegers M, Soors E, et al. Higher Initial DNA Damage and Persistent Cell Cycle Arrest after Carbon Ion Irradiation Compared to X-irradiation in Prostate and Colon Cancer Cells. Front Oncol. 2016;6:87 pubmed 出版商
Zhang X, Kluz T, Gesumaria L, Matsui M, Costa M, Sun H. Solar Simulated Ultraviolet Radiation Induces Global Histone Hypoacetylation in Human Keratinocytes. PLoS ONE. 2016;11:e0150175 pubmed 出版商
Fischer U, Ludwig N, Raslan A, Meier C, Meese E. Gene amplification during myogenic differentiation. Oncotarget. 2016;7:6864-77 pubmed 出版商
Monteforte R, Beilhack G, Grausenburger R, Mayerhofer B, Bittner R, Grillari Voglauer R, et al. SNEV(Prp19/PSO4) deficiency increases PUVA-induced senescence in mouse skin. Exp Dermatol. 2016;25:212-7 pubmed 出版商
Fan G, Sun L, Shan P, Zhang X, Huan J, Li D, et al. Loss of KLF14 triggers centrosome amplification and tumorigenesis. Nat Commun. 2015;6:8450 pubmed 出版商
Boysen G, Barbieri C, Prandi D, Blattner M, Chae S, Dahija A, et al. SPOP mutation leads to genomic instability in prostate cancer. elife. 2015;4: pubmed 出版商
Rastgou Talemi S, Kollarovic G, Lapytsko A, Schaber J. Development of a robust DNA damage model including persistent telomere-associated damage with application to secondary cancer risk assessment. Sci Rep. 2015;5:13540 pubmed 出版商
Di Giacomo M, Comazzetto S, Sampath S, Sampath S, O Carroll D. G9a co-suppresses LINE1 elements in spermatogonia. Epigenetics Chromatin. 2014;7:24 pubmed 出版商
Lowe D, Raj K. Premature aging induced by radiation exhibits pro-atherosclerotic effects mediated by epigenetic activation of CD44 expression. Aging Cell. 2014;13:900-10 pubmed 出版商
产品信息
目录号 :
ab26350
ItemName :
抗丙H2A.X(磷酸化S139)抗体[9F3]
产品类型 :
抗体
宿主物种 :
小鼠
克隆性 :
单克隆
共轭标签 :
未共轭
克隆名称 :
9F3
规格 :
100微克
物种摘要 :
Chk, Cow, Dog, Gpig, Hm, Hu, Mk, Ms, Pig, Rat, Rb, Shp
纯度 :
蛋白质G纯化
应用摘要 :
Flow Cyt, ICC/IF, IHC-P, IP, ISH, WB
公司信息
艾博抗(上海)贸易有限公司
上海市浦东新区伽利略路338号5幢4层5401室
cn.technical@abcam.com
http://www.abcam.cn
400-628-6880 86-21-5110 5938
公司总部: 英国
Abcam是全球知名的生命科学研究领域产品提供商,产品涵盖一抗、二抗、蛋白、多肽及ELISA kit。