产品简要
公司名称 :
艾博抗(上海)贸易有限公司
其他品牌 :
Epitomics, Ascent Scientific, MitoSciences
产品类型 :
抗体
产品名称 :
抗PSD95抗体[6G6-1C9]
目录 :
ab2723
规格 :
100微克
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
6G6-1C9
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀, 免疫组化-石蜡切片, 免疫组化-冰冻切片, proximity ligation assay, 其他
文章摘录数: 66
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 小鼠; 1:2000; 图 3
Lee S, Yang H, Sung Y, Kim Y, Park S. Region-Specific Differences in the Apoe4-dependent Response to Focal Brain Injury. Exp Neurobiol. 2021;30:285-293 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 3d
Han J, Kwon S, Kim Y, Choi J, Kim J, Lee Y, et al. Ablation of STAT3 in Purkinje cells reorganizes cerebellar synaptic plasticity in long-term fear memory network. elife. 2021;10: pubmed 出版商
  • proximity ligation assay; 大鼠; 1:20,000; 图 1b
Lundgren J, Vandermeulen L, Sandebring Matton A, Ahmed S, Winblad B, Di Luca M, et al. Proximity ligation assay reveals both pre- and postsynaptic localization of the APP-processing enzymes ADAM10 and BACE1 in rat and human adult brain. BMC Neurosci. 2020;21:6 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 3b
Zheng Y, Liu A, Wang Z, Cao Q, Wang W, Lin L, et al. Inhibition of EHMT1/2 rescues synaptic and cognitive functions for Alzheimer's disease. Brain. 2019;142:787-807 pubmed 出版商
  • 免疫印迹; 大鼠; 1:400; 图 3h
Wigerius M, Quinn D, Diab A, Clattenburg L, Kolar A, Qi J, et al. The polarity protein Angiomotin p130 controls dendritic spine maturation. J Cell Biol. 2018;217:715-730 pubmed 出版商
  • 免疫细胞化学; 人类; 1:500; 表 s1
Yasui T, Uezono N, Nakashima H, Noguchi H, Matsuda T, Noda Andoh T, et al. Hypoxia Epigenetically Confers Astrocytic Differentiation Potential on Human Pluripotent Cell-Derived Neural Precursor Cells. Stem Cell Reports. 2017;8:1743-1756 pubmed 出版商
  • 免疫细胞化学; 小鼠; 1:200; 图 1d
Ripamonti S, Ambrozkiewicz M, Guzzi F, Gravati M, Biella G, Bormuth I, et al. Transient oxytocin signaling primes the development and function of excitatory hippocampal neurons. elife. 2017;6: pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 3a
Stuart K, King A, Fernandez Martos C, Dittmann J, Summers M, Vickers J. Mid-life environmental enrichment increases synaptic density in CA1 in a mouse model of A?-associated pathology and positively influences synaptic and cognitive health in healthy ageing. J Comp Neurol. 2017;525:1797-1810 pubmed 出版商
  • 免疫印迹; 小鼠; 图 8e
Qin Y, Liu Y, Hao W, Decker Y, Tomic I, Menger M, et al. Stimulation of TLR4 Attenuates Alzheimer's Disease-Related Symptoms and Pathology in Tau-Transgenic Mice. J Immunol. 2016;197:3281-3292 pubmed
  • 免疫细胞化学; 大鼠; 1:1000; 图 7
Liu Z, Ding J, Yang Q, Song H, Chen X, Xu Y, et al. Early developmental bisphenol-A exposure sex-independently impairs spatial memory by remodeling hippocampal dendritic architecture and synaptic transmission in rats. Sci Rep. 2016;6:32492 pubmed 出版商
  • 免疫组化; 小鼠; 1:1000; 图 3c
Sakai Y, Fukai R, Matsushita Y, Miyake N, Saitsu H, Akamine S, et al. De Novo Truncating Mutation of TRIM8 Causes Early-Onset Epileptic Encephalopathy. Ann Hum Genet. 2016;80:235-40 pubmed 出版商
  • 免疫组化; 大鼠; 1:1000; 图 3
  • 免疫印迹; 大鼠; 1:1000; 图 3
Vasilev D, Dubrovskaya N, Tumanova N, Zhuravin I. Prenatal Hypoxia in Different Periods of Embryogenesis Differentially Affects Cell Migration, Neuronal Plasticity, and Rat Behavior in Postnatal Ontogenesis. Front Neurosci. 2016;10:126 pubmed 出版商
  • 免疫细胞化学; 小鼠; 1:100; 图 2
Schedin Weiss S, Caesar I, Winblad B, Blom H, Tjernberg L. Super-resolution microscopy reveals ?-secretase at both sides of the neuronal synapse. Acta Neuropathol Commun. 2016;4:29 pubmed 出版商
  • 其他; 大鼠; 1:500; 图 4
  • 免疫细胞化学; 大鼠; 1:500; 图 2
Schoen M, Reichel J, Demestre M, Putz S, Deshpande D, Proepper C, et al. Super-Resolution Microscopy Reveals Presynaptic Localization of the ALS/FTD Related Protein FUS in Hippocampal Neurons. Front Cell Neurosci. 2015;9:496 pubmed 出版商
  • 免疫印迹; 大鼠; 1:2000; 图 2
Boczek T, Lisek M, Ferenc B, Wiktorska M, Ivchevska I, Zylinska L. Region-specific effects of repeated ketamine administration on the presynaptic GABAergic neurochemistry in rat brain. Neurochem Int. 2015;91:13-25 pubmed 出版商
  • 免疫细胞化学; 大鼠; 1:500; 图 4
Brigidi G, Santyr B, Shimell J, Jovellar B, Bamji S. Activity-regulated trafficking of the palmitoyl-acyl transferase DHHC5. Nat Commun. 2015;6:8200 pubmed 出版商
  • 免疫印迹; 小鼠; 1:200
Chugh D, Ali I, Bakochi A, Bahonjic E, Etholm L, Ekdahl C. Alterations in Brain Inflammation, Synaptic Proteins, and Adult Hippocampal Neurogenesis during Epileptogenesis in Mice Lacking Synapsin2. PLoS ONE. 2015;10:e0132366 pubmed 出版商
  • 免疫细胞化学; 大鼠; 1:50; 图 1b
Laht P, Tammaru E, Otsus M, Rohtla J, Tiismus L, Veske A. Plexin-B3 suppresses excitatory and promotes inhibitory synapse formation in rat hippocampal neurons. Exp Cell Res. 2015;335:269-78 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1:500
Atkin G, Moore S, Lu Y, Nelson R, Tipper N, Rajpal G, et al. Loss of F-box only protein 2 (Fbxo2) disrupts levels and localization of select NMDA receptor subunits, and promotes aberrant synaptic connectivity. J Neurosci. 2015;35:6165-78 pubmed 出版商
  • 免疫印迹; 小鼠; 图 7
Lo S, Wang Y, Weber M, Larson J, Scearce Levie K, Sheng M. Caspase-3 deficiency results in disrupted synaptic homeostasis and impaired attention control. J Neurosci. 2015;35:2118-32 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 图 s3a
Kizuka Y, Kitazume S, Fujinawa R, Saito T, Iwata N, Saido T, et al. An aberrant sugar modification of BACE1 blocks its lysosomal targeting in Alzheimer's disease. EMBO Mol Med. 2015;7:175-89 pubmed 出版商
  • 免疫印迹; 小鼠
Maltecca F, Baseggio E, Consolato F, Mazza D, Podini P, Young S, et al. Purkinje neuron Ca2+ influx reduction rescues ataxia in SCA28 model. J Clin Invest. 2015;125:263-74 pubmed 出版商
  • 免疫细胞化学; 小鼠
Chivet M, Javalet C, Laulagnier K, Blot B, Hemming F, Sadoul R. Exosomes secreted by cortical neurons upon glutamatergic synapse activation specifically interact with neurons. J Extracell Vesicles. 2014;3:24722 pubmed 出版商
  • 免疫细胞化学; 大鼠; 1:200; 图 8a
Ferron L, Nieto Rostro M, Cassidy J, Dolphin A. Fragile X mental retardation protein controls synaptic vesicle exocytosis by modulating N-type calcium channel density. Nat Commun. 2014;5:3628 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000
Udagawa T, Farny N, Jakovcevski M, Kaphzan H, Alarcon J, Anilkumar S, et al. Genetic and acute CPEB1 depletion ameliorate fragile X pathophysiology. Nat Med. 2013;19:1473-7 pubmed 出版商
  • 免疫组化; 大鼠; 1:500
Blom H, Rönnlund D, Scott L, Westin L, Widengren J, Aperia A, et al. Spatial distribution of DARPP-32 in dendritic spines. PLoS ONE. 2013;8:e75155 pubmed 出版商
  • 免疫组化; 小鼠; 1:600
Houbaert X, Zhang C, Gambino F, Lepleux M, Deshors M, Normand E, et al. Target-specific vulnerability of excitatory synapses leads to deficits in associative memory in a model of intellectual disorder. J Neurosci. 2013;33:13805-19 pubmed 出版商
  • 免疫组化; 小鼠; 1:1000
Bleckert A, Parker E, Kang Y, Pancaroglu R, Soto F, Lewis R, et al. Spatial relationships between GABAergic and glutamatergic synapses on the dendrites of distinct types of mouse retinal ganglion cells across development. PLoS ONE. 2013;8:e69612 pubmed 出版商
Naia L, Pinho C, Dentoni G, Liu J, Leal N, Ferreira D, et al. Neuronal cell-based high-throughput screen for enhancers of mitochondrial function reveals luteolin as a modulator of mitochondria-endoplasmic reticulum coupling. BMC Biol. 2021;19:57 pubmed 出版商
Shimell J, Globa A, Sepers M, Wild A, Matin N, Raymond L, et al. Regulation of hippocampal excitatory synapses by the Zdhhc5 palmitoyl acyltransferase. J Cell Sci. 2021;134: pubmed 出版商
Shimell J, Shah B, Cain S, Thouta S, Kuhlmann N, Tatarnikov I, et al. The X-Linked Intellectual Disability Gene Zdhhc9 Is Essential for Dendrite Outgrowth and Inhibitory Synapse Formation. Cell Rep. 2019;29:2422-2437.e8 pubmed 出版商
Matsuda T, Oinuma I. Imaging endogenous synaptic proteins in primary neurons at single-cell resolution using CRISPR/Cas9. Mol Biol Cell. 2019;30:2838-2855 pubmed 出版商
Arber C, Toombs J, Lovejoy C, Ryan N, Paterson R, Willumsen N, et al. Familial Alzheimer's disease patient-derived neurons reveal distinct mutation-specific effects on amyloid beta. Mol Psychiatry. 2019;: pubmed 出版商
Dinamarca M, Raveh A, Schneider A, Fritzius T, Früh S, Rem P, et al. Complex formation of APP with GABAB receptors links axonal trafficking to amyloidogenic processing. Nat Commun. 2019;10:1331 pubmed 出版商
Durand A, Wiesner T, Gardner M, Robitaille L, Bilodeau A, Gagné C, et al. A machine learning approach for online automated optimization of super-resolution optical microscopy. Nat Commun. 2018;9:5247 pubmed 出版商
Sun H, Ma L, Zhang Y, Pan X, Wang C, Zhang J, et al. A Purinergic P2 Receptor Family-Mediated Increase in Thrombospondin-1 Bolsters Synaptic Density and Epileptic Seizure Activity in the Amygdala-Kindling Rat Model. Front Cell Neurosci. 2018;12:302 pubmed 出版商
Woodhouse A, Fernández Martos C, Atkinson R, Hanson K, Collins J, O Mara A, et al. Repeat propofol anesthesia does not exacerbate plaque deposition or synapse loss in APP/PS1 Alzheimer's disease mice. BMC Anesthesiol. 2018;18:47 pubmed 出版商
Li P, Fu X, Smith N, Ziobro J, Curiel J, Tenga M, et al. Loss of CLOCK Results in Dysfunction of Brain Circuits Underlying Focal Epilepsy. Neuron. 2017;96:387-401.e6 pubmed 出版商
Efimova N, Korobova F, Stankewich M, Moberly A, Stolz D, Wang J, et al. ?III Spectrin Is Necessary for Formation of the Constricted Neck of Dendritic Spines and Regulation of Synaptic Activity in Neurons. J Neurosci. 2017;37:6442-6459 pubmed 出版商
Cacciottolo M, Wang X, Driscoll I, Woodward N, Saffari A, Reyes J, et al. Particulate air pollutants, APOE alleles and their contributions to cognitive impairment in older women and to amyloidogenesis in experimental models. Transl Psychiatry. 2017;7:e1022 pubmed 出版商
Orr M, Garbarino V, Salinas A, Buffenstein R. Extended Postnatal Brain Development in the Longest-Lived Rodent: Prolonged Maintenance of Neotenous Traits in the Naked Mole-Rat Brain. Front Neurosci. 2016;10:504 pubmed
Waaijers S, Muñoz J, Berends C, Ramalho J, Goerdayal S, Low T, et al. A tissue-specific protein purification approach in Caenorhabditis elegans identifies novel interaction partners of DLG-1/Discs large. BMC Biol. 2016;14:66 pubmed 出版商
Belmer A, Klenowski P, Patkar O, Bartlett S. Mapping the connectivity of serotonin transporter immunoreactive axons to excitatory and inhibitory neurochemical synapses in the mouse limbic brain. Brain Struct Funct. 2017;222:1297-1314 pubmed 出版商
Cagalinec M, Liiv M, Hodurova Z, Hickey M, Vaarmann A, Mandel M, et al. Role of Mitochondrial Dynamics in Neuronal Development: Mechanism for Wolfram Syndrome. PLoS Biol. 2016;14:e1002511 pubmed 出版商
Bernstock J, Lee Y, Peruzzotti Jametti L, Southall N, Johnson K, Maric D, et al. A novel quantitative high-throughput screen identifies drugs that both activate SUMO conjugation via the inhibition of microRNAs 182 and 183 and facilitate neuroprotection in a model of oxygen and glucose deprivation. J Cereb Blood Flow Metab. 2016;36:426-41 pubmed 出版商
Roy A, Modi K, Khasnavis S, Ghosh S, Watson R, Pahan K. Enhancement of morphological plasticity in hippocampal neurons by a physically modified saline via phosphatidylinositol-3 kinase. PLoS ONE. 2014;9:e101883 pubmed 出版商
Frandemiche M, De Seranno S, Rush T, Borel E, Elie A, Arnal I, et al. Activity-dependent tau protein translocation to excitatory synapse is disrupted by exposure to amyloid-beta oligomers. J Neurosci. 2014;34:6084-97 pubmed 出版商
Jausoro I, Mestres I, Quassollo G, Masseroni L, Heredia F, Caceres A. Regulation of spine density and morphology by IQGAP1 protein domains. PLoS ONE. 2013;8:e56574 pubmed 出版商
Li M, Masugi Tokita M, Takanami K, Yamada S, Kawata M. Testosterone has sublayer-specific effects on dendritic spine maturation mediated by BDNF and PSD-95 in pyramidal neurons in the hippocampus CA1 area. Brain Res. 2012;1484:76-84 pubmed 出版商
Shapiro Reznik M, Jilg A, Lerner H, Earnest D, Zisapel N. Diurnal rhythms in neurexins transcripts and inhibitory/excitatory synapse scaffold proteins in the biological clock. PLoS ONE. 2012;7:e37894 pubmed 出版商
Jackson J, Chugh D, Nilsson P, Wood J, Carlström K, Lindvall O, et al. Altered synaptic properties during integration of adult-born hippocampal neurons following a seizure insult. PLoS ONE. 2012;7:e35557 pubmed 出版商
Cousins S, Stephenson F. Identification of N-methyl-D-aspartic acid (NMDA) receptor subtype-specific binding sites that mediate direct interactions with scaffold protein PSD-95. J Biol Chem. 2012;287:13465-76 pubmed 出版商
Ren W, Liu Y, Li B. Stimulation of ?(2A)-adrenoceptors promotes the maturation of dendritic spines in cultured neurons of the medial prefrontal cortex. Mol Cell Neurosci. 2012;49:205-16 pubmed 出版商
Joseph B, Thakali K, Pathan A, Kang E, Rusch N, Rhee S. Postsynaptic density-95 scaffolding of Shaker-type K? channels in smooth muscle cells regulates the diameter of cerebral arteries. J Physiol. 2011;589:5143-52 pubmed 出版商
Sinning A, Liebmann L, Kougioumtzes A, Westermann M, Bruehl C, Hübner C. Synaptic glutamate release is modulated by the Na+ -driven Cl-/HCO?? exchanger Slc4a8. J Neurosci. 2011;31:7300-11 pubmed 出版商
Schmitz S, Hjorth J, Joemai R, Wijntjes R, Eijgenraam S, de Bruijn P, et al. Automated analysis of neuronal morphology, synapse number and synaptic recruitment. J Neurosci Methods. 2011;195:185-93 pubmed 出版商
Oliveira T, Chan R, Tian H, Laredo M, Shui G, Staniszewski A, et al. Phospholipase d2 ablation ameliorates Alzheimer's disease-linked synaptic dysfunction and cognitive deficits. J Neurosci. 2010;30:16419-28 pubmed 出版商
Blazquez C, Chiarlone A, Sagredo O, Aguado T, Pazos M, Resel E, et al. Loss of striatal type 1 cannabinoid receptors is a key pathogenic factor in Huntington's disease. Brain. 2011;134:119-36 pubmed 出版商
Wei J, Liu W, Yan Z. Regulation of AMPA receptor trafficking and function by glycogen synthase kinase 3. J Biol Chem. 2010;285:26369-76 pubmed 出版商
Li Y, Hu J, Höfer K, Wong A, Cooper J, Birnbaum S, et al. DHHC5 interacts with PDZ domain 3 of post-synaptic density-95 (PSD-95) protein and plays a role in learning and memory. J Biol Chem. 2010;285:13022-31 pubmed 出版商
Gonçalves J, Baptista S, Martins T, Milhazes N, Borges F, Ribeiro C, et al. Methamphetamine-induced neuroinflammation and neuronal dysfunction in the mice hippocampus: preventive effect of indomethacin. Eur J Neurosci. 2010;31:315-26 pubmed 出版商
Hoon M, Bauer G, Fritschy J, Moser T, Falkenburger B, Varoqueaux F. Neuroligin 2 controls the maturation of GABAergic synapses and information processing in the retina. J Neurosci. 2009;29:8039-50 pubmed 出版商
Olah M, Jackson M, Li H, Perez Y, Sun H, Kiyonaka S, et al. Ca2+-dependent induction of TRPM2 currents in hippocampal neurons. J Physiol. 2009;587:965-79 pubmed 出版商
Steinert J, Kopp Scheinpflug C, Baker C, Challiss R, Mistry R, Haustein M, et al. Nitric oxide is a volume transmitter regulating postsynaptic excitability at a glutamatergic synapse. Neuron. 2008;60:642-56 pubmed 出版商
Haeckel A, Ahuja R, Gundelfinger E, Qualmann B, Kessels M. The actin-binding protein Abp1 controls dendritic spine morphology and is important for spine head and synapse formation. J Neurosci. 2008;28:10031-44 pubmed 出版商
Reisinger E, Zimmermann U, Knipper M, Ludwig J, Klocker N, Fakler B, et al. Cod106, a novel synaptic protein expressed in sensory hair cells of the inner ear and in CNS neurons. Mol Cell Neurosci. 2005;28:106-17 pubmed
产品信息
目录号 :
ab2723
ItemName :
抗PSD95抗体[6G6-1C9]
产品类型 :
一抗
宿主物种 :
小鼠
克隆性 :
单克隆
共轭标签 :
Not Conjugated
抗原修饰 :
No Modifications
克隆名称 :
6G6-1C9
规格 :
100微克
物种摘要 :
Ms, Rat, Zfsh
用途 :
IHC-Fr, IHC-P, IP, WB
规格说明 :
Other sizes available: 100 µl
公司信息
艾博抗(上海)贸易有限公司
上海市浦东新区伽利略路338号5幢4层5401室
cn.technical@abcam.com
http://www.abcam.cn
400-628-6880 86-21-5110 5938
公司总部: 英国
Abcam是全球知名的生命科学研究领域产品提供商,产品涵盖一抗、二抗、蛋白、多肽及ELISA kit。