产品简要
公司名称 :
艾博抗(上海)贸易有限公司
其他品牌 :
Epitomics, Ascent Scientific, MitoSciences
产品类型 :
抗体
产品名称 :
抗Smad3抗体-ChIP级
目录 :
ab28379
规格 :
1毫升
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 免疫细胞化学, 免疫沉淀, 染色质免疫沉淀 , 免疫组化-石蜡切片, 免疫组化-冰冻切片, ChIP-Seq, 免疫印迹基因敲除验证
文章摘录数: 25
出版应用/物种/样本/稀释参考文献
  • 免疫细胞化学; 人类; 1:200; 图 6q
  • 免疫印迹; 人类; 图 6f
  • 免疫细胞化学; 小鼠; 1:200; 图 6c
  • 免疫印迹; 小鼠; 图 6e
Xi Y, Li Y, Xu P, Li S, Liu Z, Tung H, et al. The anti-fibrotic drug pirfenidone inhibits liver fibrosis by targeting the small oxidoreductase glutaredoxin-1. Sci Adv. 2021;7:eabg9241 pubmed 出版商
  • 免疫印迹基因敲除验证; 小鼠; 图 2c
Ge J, Burnier L, Adamopoulou M, Kwa M, Schaks M, Rottner K, et al. RhoA, Rac1, and Cdc42 differentially regulate αSMA and collagen I expression in mesenchymal stem cells. J Biol Chem. 2018;293:9358-9369 pubmed 出版商
  • 免疫印迹; 人类; 1:100; 图 s1a
Lino Cardenas C, Kessinger C, Cheng Y, MacDonald C, Macgillivray T, Ghoshhajra B, et al. An HDAC9-MALAT1-BRG1 complex mediates smooth muscle dysfunction in thoracic aortic aneurysm. Nat Commun. 2018;9:1009 pubmed 出版商
  • 免疫印迹; 小鼠; 图 s16
Wassermann Dozorets R, Rubinstein M. C/EBPβ LIP augments cell death by inducing osteoglycin. Cell Death Dis. 2017;8:e2733 pubmed 出版商
  • ChIP-Seq; 小鼠; 图 6
Eichenfield D, Troutman T, Link V, Lam M, Cho H, Gosselin D, et al. Tissue damage drives co-localization of NF-?B, Smad3, and Nrf2 to direct Rev-erb sensitive wound repair in mouse macrophages. elife. 2016;5: pubmed 出版商
  • 免疫沉淀; 小鼠; 图 6
  • 免疫印迹; 小鼠; 图 2
Hwang S, Jang S, Kim M, Kim L, Kim B, Kim H, et al. YY1 inhibits differentiation and function of regulatory T cells by blocking Foxp3 expression and activity. Nat Commun. 2016;7:10789 pubmed 出版商
  • 免疫印迹; 人类; 图 1
Micha D, Voermans E, Eekhoff M, van Essen H, Zandieh Doulabi B, Netelenbos C, et al. Inhibition of TGFβ signaling decreases osteogenic differentiation of fibrodysplasia ossificans progressiva fibroblasts in a novel in vitro model of the disease. Bone. 2016;84:169-180 pubmed 出版商
Papoutsoglou P, Tsubakihara Y, Caja L, Morén A, Pallis P, Ameur A, et al. The TGFB2-AS1 lncRNA Regulates TGF-β Signaling by Modulating Corepressor Activity. Cell Rep. 2019;28:3182-3198.e11 pubmed 出版商
Rossi M, Bucci G, Rizzotto D, Bordo D, Marzi M, Puppo M, et al. LncRNA EPR controls epithelial proliferation by coordinating Cdkn1a transcription and mRNA decay response to TGF-β. Nat Commun. 2019;10:1969 pubmed 出版商
Naciri I, Laisné M, Ferry L, Bourmaud M, Gupta N, Di Carlo S, et al. Genetic screens reveal mechanisms for the transcriptional regulation of tissue-specific genes in normal cells and tumors. Nucleic Acids Res. 2019;47:3407-3421 pubmed 出版商
Kolliopoulos C, Raja E, Razmara M, Heldin P, Heldin C, Moustakas A, et al. Transforming growth factor β (TGFβ) induces NUAK kinase expression to fine-tune its signaling output. J Biol Chem. 2019;294:4119-4136 pubmed 出版商
Fenizia C, Bottino C, Corbetta S, Fittipaldi R, Floris P, Gaudenzi G, et al. SMYD3 promotes the epithelial-mesenchymal transition in breast cancer. Nucleic Acids Res. 2019;47:1278-1293 pubmed 出版商
Fang L, Wu S, Zhu X, Cai J, Wu J, He Z, et al. MYEOV functions as an amplified competing endogenous RNA in promoting metastasis by activating TGF-β pathway in NSCLC. Oncogene. 2019;38:896-912 pubmed 出版商
Iyer D, Zhao Q, Wirka R, Naravane A, Nguyen T, Liu B, et al. Coronary artery disease genes SMAD3 and TCF21 promote opposing interactive genetic programs that regulate smooth muscle cell differentiation and disease risk. PLoS Genet. 2018;14:e1007681 pubmed 出版商
Vervoort S, Lourenço A, Tufegdzic Vidakovic A, Mocholí E, Sandoval J, Rueda O, et al. SOX4 can redirect TGF-β-mediated SMAD3-transcriptional output in a context-dependent manner to promote tumorigenesis. Nucleic Acids Res. 2018;46:9578-9590 pubmed 出版商
Tang Y, Tang L, Xu X, Li C, Deng C, Zhang Y. Generation of Smurf2 Conditional Knockout Mice. Int J Biol Sci. 2018;14:542-548 pubmed 出版商
Fueyo R, Iacobucci S, PAPPA S, Estarás C, Lois S, Vicioso Mantis M, et al. Lineage specific transcription factors and epigenetic regulators mediate TGF?-dependent enhancer activation. Nucleic Acids Res. 2018;46:3351-3365 pubmed 出版商
Shuttleworth V, Gaughan L, Nawafa L, Mooney C, Cobb S, Sheerin N, et al. The methyltransferase SET9 regulates TGFB1 activation of renal fibroblasts via interaction with SMAD3. J Cell Sci. 2018;131: pubmed 出版商
Ruetz T, Pfisterer U, Di Stefano B, Ashmore J, Beniazza M, Tian T, et al. Constitutively Active SMAD2/3 Are Broad-Scope Potentiators of Transcription-Factor-Mediated Cellular Reprogramming. Cell Stem Cell. 2017;21:791-805.e9 pubmed 出版商
Hu J, Tian J, Zhu S, Sun L, Yu J, Tian H, et al. Sox5 contributes to prostate cancer metastasis and is a master regulator of TGF-β-induced epithelial mesenchymal transition through controlling Twist1 expression. Br J Cancer. 2018;118:88-97 pubmed 出版商
Ojiaku C, Cao G, Zhu W, Yoo E, Shumyatcher M, Himes B, et al. TGF-β1 Evokes Human Airway Smooth Muscle Cell Shortening and Hyperresponsiveness via Smad3. Am J Respir Cell Mol Biol. 2017;: pubmed 出版商
Seth B, Yadav A, Agarwal S, Tiwari S, Chaturvedi R. Inhibition of the transforming growth factor-β/SMAD cascade mitigates the anti-neurogenic effects of the carbamate pesticide carbofuran. J Biol Chem. 2017;292:19423-19440 pubmed 出版商
Khalil H, Kanisicak O, Prasad V, Correll R, Fu X, Schips T, et al. Fibroblast-specific TGF-?-Smad2/3 signaling underlies cardiac fibrosis. J Clin Invest. 2017;127:3770-3783 pubmed 出版商
Tang L, Heller M, Meng Z, Yu L, Tang Y, Zhou M, et al. Transforming Growth Factor-β (TGF-β) Directly Activates the JAK1-STAT3 Axis to Induce Hepatic Fibrosis in Coordination with the SMAD Pathway. J Biol Chem. 2017;292:4302-4312 pubmed 出版商
Yamamoto K, Tateishi K, Kudo Y, Hoshikawa M, Tanaka M, Nakatsuka T, et al. Stromal remodeling by the BET bromodomain inhibitor JQ1 suppresses the progression of human pancreatic cancer. Oncotarget. 2016;7:61469-61484 pubmed 出版商
产品信息
目录号 :
ab28379
ItemName :
抗Smad3抗体-ChIP级
产品类型 :
一抗
宿主物种 :
克隆性 :
多克隆
共轭标签 :
Not Conjugated
抗原修饰 :
No Modifications
规格 :
1毫升
物种摘要 :
Hu, Ms, Rat
用途 :
ChIP, ICC/IF, IHC-Fr, IHC-P, IP, WB
规格说明 :
Other sizes available: 100 µg,100 µl,500 µl
公司信息
艾博抗(上海)贸易有限公司
上海市浦东新区伽利略路338号5幢4层5401室
cn.technical@abcam.com
http://www.abcam.cn
400-628-6880 86-21-5110 5938
公司总部: 英国
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