产品简要
公司名称 :
艾博抗(上海)贸易有限公司
其他品牌 :
Epitomics, Ascent Scientific, MitoSciences
产品类型 :
抗体
产品名称 :
抗丙H2A.X(磷酸化S139)抗体-ChIP级
目录 :
ab2893
规格 :
3.5毫升
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
抗原修饰 :
磷酸化
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀, 染色质免疫沉淀 , 免疫组化-石蜡切片, ChIP-Seq
文章摘录数: 62
出版应用/物种/样本/稀释参考文献
  • 免疫细胞化学; 人类; 图 1d
  • 免疫印迹; 人类; 1:1000; 图 5g
Lei X, Cao K, Chen Y, Shen H, Liu Z, Qin H, et al. Nuclear Transglutaminase 2 interacts with topoisomerase II⍺ to promote DNA damage repair in lung cancer cells. J Exp Clin Cancer Res. 2021;40:224 pubmed 出版商
  • 免疫组化; 小鼠; 1:100; 图 5b
Martínez Vicente I, Abrisqueta M, Herraiz C, Sires Campos J, Castejón Griñán M, Bennett D, et al. Mahogunin Ring Finger 1 Is Required for Genomic Stability and Modulates the Malignant Phenotype of Melanoma Cells. Cancers (Basel). 2020;12: pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:100; 图 s19a
  • 免疫印迹; 人类; 1:1000; 图 3d
Meng X, Zhao Y, Han B, Zha C, Zhang Y, Li Z, et al. Dual functionalized brain-targeting nanoinhibitors restrain temozolomide-resistant glioma via attenuating EGFR and MET signaling pathways. Nat Commun. 2020;11:594 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 1s2a
Onn L, Portillo M, Ilic S, Cleitman G, Stein D, Kaluski S, et al. SIRT6 is a DNA double-strand break sensor. elife. 2020;9: pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 6c
Orgaz J, Crosas Molist E, Sadok A, Perdrix Rosell A, Maiques O, Rodriguez Hernandez I, et al. Myosin II Reactivation and Cytoskeletal Remodeling as a Hallmark and a Vulnerability in Melanoma Therapy Resistance. Cancer Cell. 2020;37:85-103.e9 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:200; 图 1f
Sun C, Guo E, Zhou B, Shan W, Huang J, Weng D, et al. A reactive oxygen species scoring system predicts cisplatin sensitivity and prognosis in ovarian cancer patients. BMC Cancer. 2019;19:1061 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 图 4a
Zhang J, Zhang X, Zhang Y, Zeng W, Zhao S, Liu M. Normal spermatogenesis in Fank1 (fibronectin type 3 and ankyrin repeat domains 1) mutant mice. Peerj. 2019;7:e6827 pubmed 出版商
  • 免疫印迹; 小鼠; 图 5b
Bartova E, Lochmanová G, Legartova S, Suchankova J, Fedr R, Krejci J, et al. Irradiation by γ-rays reduces the level of H3S10 phosphorylation and weakens the G2 phase-dependent interaction between H3S10 phosphorylation and γH2AX. Biochimie. 2018;154:86-98 pubmed 出版商
  • 免疫印迹; 人类; 图 7a
Xiao G, Chan L, Klemm L, Braas D, Chen Z, Geng H, et al. B-Cell-Specific Diversion of Glucose Carbon Utilization Reveals a Unique Vulnerability in B Cell Malignancies. Cell. 2018;173:470-484.e18 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 4a
Yang R, Tao Z, Huang M, Zheng Y, Dai M, Zou Y, et al. Knockout of the placenta specific 8 gene radiosensitizes nasopharyngeal carcinoma cells by activating the PI3K/AKT/GSK3β pathway. Am J Transl Res. 2018;10:455-464 pubmed
  • 染色质免疫沉淀 ; 小鼠; 图 4h
  • 免疫组化; 小鼠; 1:200; 图 5h
Fu X, Zhang C, Meng H, Zhang K, Shi L, Cao C, et al. Oncoprotein Tudor-SN is a key determinant providing survival advantage under DNA damaging stress. Cell Death Differ. 2018;25:1625-1637 pubmed 出版商
  • 免疫组化; 人类; 1:1000; 图 1a
Wang Y, Hariharan A, Bastianello G, Toyama Y, Shivashankar G, Foiani M, et al. DNA damage causes rapid accumulation of phosphoinositides for ATR signaling. Nat Commun. 2017;8:2118 pubmed 出版商
  • 免疫细胞化学; 小鼠; 1:200; 图 s4c
Tu Z, Bayazit M, Liu H, Zhang J, Busayavalasa K, Risal S, et al. Speedy A-Cdk2 binding mediates initial telomere-nuclear envelope attachment during meiotic prophase I independent of Cdk2 activation. Proc Natl Acad Sci U S A. 2017;114:592-597 pubmed 出版商
  • 免疫组化; 人类; 图 2b
Hill S, Mordes D, Cameron L, Neuberg D, Landini S, Eggan K, et al. Two familial ALS proteins function in prevention/repair of transcription-associated DNA damage. Proc Natl Acad Sci U S A. 2016;113:E7701-E7709 pubmed
  • 免疫印迹; 人类; 1:1000; 图 2a
Sundar I, Javed F, Romanos G, Rahman I. E-cigarettes and flavorings induce inflammatory and pro-senescence responses in oral epithelial cells and periodontal fibroblasts. Oncotarget. 2016;7:77196-77204 pubmed 出版商
  • 免疫组化-石蜡切片; 大鼠; 1:100; 图 14
Ta M, Schwensen K, Liuwantara D, Huso D, Watnick T, Rangan G. Constitutive renal Rel/nuclear factor-?B expression in Lewis polycystic kidney disease rats. World J Nephrol. 2016;5:339-57 pubmed 出版商
  • 染色质免疫沉淀 ; 人类; 图 7
Morales J, Richard P, Patidar P, Motea E, Dang T, Manley J, et al. XRN2 Links Transcription Termination to DNA Damage and Replication Stress. PLoS Genet. 2016;12:e1006107 pubmed 出版商
  • 免疫印迹; 人类; 图 7e
Su C, Cheng C, Tzeng T, Lin I, Hsu M. An H2A Histone Isotype, H2ac, Associates with Telomere and Maintains Telomere Integrity. PLoS ONE. 2016;11:e0156378 pubmed 出版商
  • 免疫细胞化学; 人类; 1:200; 图 4
Maillet A, TAN K, Chai X, Sadananda S, Mehta A, Ooi J, et al. Modeling Doxorubicin-Induced Cardiotoxicity in Human Pluripotent Stem Cell Derived-Cardiomyocytes. Sci Rep. 2016;6:25333 pubmed 出版商
  • 免疫细胞化学; 人类; 图 2a
Garcia C, Videla Richardson G, Dimopoulos N, Fernandez Espinosa D, Miriuka S, Sevlever G, et al. Human Pluripotent Stem Cells and Derived Neuroprogenitors Display Differential Degrees of Susceptibility to BH3 Mimetics ABT-263, WEHI-539 and ABT-199. PLoS ONE. 2016;11:e0152607 pubmed 出版商
  • 免疫细胞化学; 人类; 1:1000; 图 4c
Daly O, Gaboriau D, Karakaya K, King S, Dantas T, Lalor P, et al. CEP164-null cells generated by genome editing show a ciliation defect with intact DNA repair capacity. J Cell Sci. 2016;129:1769-74 pubmed 出版商
  • ChIP-Seq; 人类; 图 4
  • 免疫细胞化学; 人类; 图 5g
Capell B, Drake A, Zhu J, Shah P, Dou Z, Dorsey J, et al. MLL1 is essential for the senescence-associated secretory phenotype. Genes Dev. 2016;30:321-36 pubmed 出版商
  • 免疫细胞化学; 人类; 图 3b
  • 免疫印迹; 人类; 图 4a
Baude A, Aaes T, Zhai B, Al Nakouzi N, Oo H, Daugaard M, et al. Hepatoma-derived growth factor-related protein 2 promotes DNA repair by homologous recombination. Nucleic Acids Res. 2016;44:2214-26 pubmed 出版商
  • 免疫印迹; 小鼠; 1:2000; 图 4
Shapiro A, Miller Pinsler L, Wells P. Breast cancer 1 (BRCA1)-deficient embryos develop normally but are more susceptible to ethanol-initiated DNA damage and embryopathies. Redox Biol. 2016;7:30-38 pubmed 出版商
Huang W, Tang H, Wen F, Lu X, Li Q, Shu P. Jianpi-yangwei decoction inhibits DNA damage repair in the drug resistance of gastric cancer by reducing FEN1 expression. BMC Complement Med Ther. 2020;20:196 pubmed 出版商
Dhoonmoon A, Schleicher E, Clements K, Nicolae C, Moldovan G. Genome-wide CRISPR synthetic lethality screen identifies a role for the ADP-ribosyltransferase PARP14 in DNA replication dynamics controlled by ATR. Nucleic Acids Res. 2020;48:7252-7264 pubmed 出版商
Lipinski M, Muñoz Viana R, Del Blanco B, Marquez Galera A, Medrano Relinque J, Caramés J, et al. KAT3-dependent acetylation of cell type-specific genes maintains neuronal identity in the adult mouse brain. Nat Commun. 2020;11:2588 pubmed 出版商
Brenner E, Schörg B, Ahmetlić F, Wieder T, Hilke F, Simon N, et al. Cancer immune control needs senescence induction by interferon-dependent cell cycle regulator pathways in tumours. Nat Commun. 2020;11:1335 pubmed 出版商
Legartova S, Lochmanová G, Zdrahal Z, Kozubek S, Sponer J, Krepl M, et al. DNA Damage Changes Distribution Pattern and Levels of HP1 Protein Isoforms in the Nucleolus and Increases Phosphorylation of HP1β-Ser88. Cells. 2019;8: pubmed 出版商
Videla Richardson G, Furmento V, Garcia C, Morris Hanon O, Sevlever G, Romorini L, et al. Human embryonic stem cells display a pronounced sensitivity to the cyclin dependent kinase inhibitor Roscovitine. BMC Mol Cell Biol. 2019;20:40 pubmed 出版商
Miao J, Liu J, Niu J, Zhang Y, Shen W, Luo C, et al. Wnt/β-catenin/RAS signaling mediates age-related renal fibrosis and is associated with mitochondrial dysfunction. Aging Cell. 2019;18:e13004 pubmed 出版商
Li J, Dang N, Martínez López N, Jowsey P, Huang D, Lightowlers R, et al. M2I-1 disrupts the in vivo interaction between CDC20 and MAD2 and increases the sensitivities of cancer cell lines to anti-mitotic drugs via MCL-1s. Cell Div. 2019;14:5 pubmed 出版商
Turner H, Lee Y, Weber W, Melo D, Kowell A, Ghandhi S, et al. Effect of dose and dose rate on temporal γ-H2AX kinetics in mouse blood and spleen mononuclear cells in vivo following Cesium-137 administration. BMC Mol Cell Biol. 2019;20:13 pubmed 出版商
de Almeida B, Noronha R, da Costa M, Nagamachi C, Pieczarka J. Meiosis in the scorpion Tityus silvestris: new insights into achiasmatic chromosomes. Biol Open. 2019;8: pubmed 出版商
Ooi J, Langley S, Xu X, Utami K, Sim B, Huang Y, et al. Unbiased Profiling of Isogenic Huntington Disease hPSC-Derived CNS and Peripheral Cells Reveals Strong Cell-Type Specificity of CAG Length Effects. Cell Rep. 2019;26:2494-2508.e7 pubmed 出版商
Anderson R, Lagnado A, Maggiorani D, Walaszczyk A, Dookun E, Chapman J, et al. Length-independent telomere damage drives post-mitotic cardiomyocyte senescence. EMBO J. 2019;38: pubmed 出版商
Chow H, Cheng A, Song X, Swerdel M, Hart R, Herrup K. ATM is activated by ATP depletion and modulates mitochondrial function through NRF1. J Cell Biol. 2019;218:909-928 pubmed 出版商
Li X, Marshall P, Leighton L, Zajaczkowski E, Wang Z, Madugalle S, et al. The DNA Repair-Associated Protein Gadd45γ Regulates the Temporal Coding of Immediate Early Gene Expression within the Prelimbic Prefrontal Cortex and Is Required for the Consolidation of Associative Fear Memory. J Neurosci. 2019;39:970-983 pubmed 出版商
Yu T, Xue P, Cui S, Zhang L, Zhang G, Xiao M, et al. Rs3212986 polymorphism, a possible biomarker to predict smoking-related lung cancer, alters DNA repair capacity via regulating ERCC1 expression. Cancer Med. 2018;7:6317-6330 pubmed 出版商
Guha M, Srinivasan S, Johnson F, Ruthel G, Guja K, Garcia Diaz M, et al. hnRNPA2 mediated acetylation reduces telomere length in response to mitochondrial dysfunction. PLoS ONE. 2018;13:e0206897 pubmed 出版商
Zhang M, Zhao K, Xu X, Yang Y, Yan S, Wei P, et al. A peptide encoded by circular form of LINC-PINT suppresses oncogenic transcriptional elongation in glioblastoma. Nat Commun. 2018;9:4475 pubmed 出版商
Svobodová Kovaříková A, Legartova S, Krejci J, Bartova E. H3K9me3 and H4K20me3 represent the epigenetic landscape for 53BP1 binding to DNA lesions. Aging (Albany NY). 2018;10:2585-2605 pubmed 出版商
Villiger L, Grisch Chan H, Lindsay H, Ringnalda F, Pogliano C, Allegri G, et al. Treatment of a metabolic liver disease by in vivo genome base editing in adult mice. Nat Med. 2018;24:1519-1525 pubmed 出版商
Hayashi Y, Fujimura A, Kato K, Udagawa R, Hirota T, Kimura K. Nucleolar integrity during interphase supports faithful Cdk1 activation and mitotic entry. Sci Adv. 2018;4:eaap7777 pubmed 出版商
Vorhagen S, Kleefisch D, Persa O, Graband A, Schwickert A, Saynisch M, et al. Shared and independent functions of aPKCλ and Par3 in skin tumorigenesis. Oncogene. 2018;37:5136-5146 pubmed 出版商
Panneer Selvam S, Roth B, Nganga R, Kim J, Cooley M, Helke K, et al. Balance between senescence and apoptosis is regulated by telomere damage-induced association between p16 and caspase-3. J Biol Chem. 2018;293:9784-9800 pubmed 出版商
Bueno M, Baldascini M, Richard S, Lowndes N. Recruitment of lysine demethylase 2A to DNA double strand breaks and its interaction with 53BP1 ensures genome stability. Oncotarget. 2018;9:15915-15930 pubmed 出版商
Ferrer C, Alders M, Postma A, Park S, Klein M, Cetinbaş M, et al. An inactivating mutation in the histone deacetylase SIRT6 causes human perinatal lethality. Genes Dev. 2018;32:373-388 pubmed 出版商
Gregorova S, Gergelits V, Chvatalova I, Bhattacharyya T, Valiskova B, Fotopulosova V, et al. Modulation of Prdm9-controlled meiotic chromosome asynapsis overrides hybrid sterility in mice. elife. 2018;7: pubmed 出版商
D Ignazio L, Michel M, Beyer M, Thompson K, Forabosco A, Schlessinger D, et al. Lhx8 ablation leads to massive autophagy of mouse oocytes associated with DNA damage. Biol Reprod. 2018;98:532-542 pubmed 出版商
Michelini F, Pitchiaya S, Vitelli V, Sharma S, Gioia U, Pessina F, et al. Damage-induced lncRNAs control the DNA damage response through interaction with DDRNAs at individual double-strand breaks. Nat Cell Biol. 2017;19:1400-1411 pubmed 出版商
Dou Z, Ghosh K, Vizioli M, Zhu J, Sen P, Wangensteen K, et al. Cytoplasmic chromatin triggers inflammation in senescence and cancer. Nature. 2017;550:402-406 pubmed 出版商
Ju H, Lu Y, Wu Q, Liu J, Zeng Z, Mo H, et al. Disrupting G6PD-mediated Redox homeostasis enhances chemosensitivity in colorectal cancer. Oncogene. 2017;36:6282-6292 pubmed 出版商
Fu H, Zhang T, Huang R, Yang Z, Liu C, Li M, et al. Calcitonin gene-related peptide protects type II alveolar epithelial cells from hyperoxia-induced DNA damage and cell death. Exp Ther Med. 2017;13:1279-1284 pubmed 出版商
Guha M, Saare M, Maslovskaja J, Kisand K, Liiv I, Haljasorg U, et al. DNA breaks and chromatin structural changes enhance the transcription of autoimmune regulator target genes. J Biol Chem. 2017;292:6542-6554 pubmed 出版商
Xie Q, Li C, Song X, Wu L, Jiang Q, Qiu Z, et al. Folate deficiency facilitates recruitment of upstream binding factor to hot spots of DNA double-strand breaks of rRNA genes and promotes its transcription. Nucleic Acids Res. 2017;45:2472-2489 pubmed 出版商
Xu C, Zhang L, Duan L, Lu C. MicroRNA-3196 is inhibited by H2AX phosphorylation and attenuates lung cancer cell apoptosis by downregulating PUMA. Oncotarget. 2016;7:77764-77776 pubmed 出版商
Dong G, Chen Q, Jiang F, Yu D, Mao Q, Xia W, et al. Diisopropylamine dichloroacetate enhances radiosensitization in esophageal squamous cell carcinoma by increasing mitochondria-derived reactive oxygen species levels. Oncotarget. 2016;7:68170-68178 pubmed 出版商
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产品信息
目录号 :
ab2893
ItemName :
抗丙H2A.X(磷酸化S139)抗体-ChIP级
产品类型 :
一抗
宿主物种 :
克隆性 :
多克隆
共轭标签 :
Not Conjugated
抗原修饰 :
磷酸化(139S)
规格 :
3.5毫升
物种摘要 :
Hu, Ms, Rat
用途 :
ChIP, ChIP/Chip, ICC, ICC/IF, IHC-FoFr, IHC-P, IP, WB
规格说明 :
Other sizes available: 25 µg,50 µg,100 µl,200 µl,400 µl,500 µl,1000 µl
公司信息
艾博抗(上海)贸易有限公司
上海市浦东新区伽利略路338号5幢4层5401室
cn.technical@abcam.com
http://www.abcam.cn
400-628-6880 86-21-5110 5938
公司总部: 英国
Abcam是全球知名的生命科学研究领域产品提供商,产品涵盖一抗、二抗、蛋白、多肽及ELISA kit。