产品简要
公司名称 :
艾博抗(上海)贸易有限公司
其他品牌 :
Epitomics, Ascent Scientific, MitoSciences
产品类型 :
抗体
产品名称 :
抗活性的胱氨酸-天冬氨酸蛋白酶3抗体[E83-77]
目录 :
ab32042
规格 :
10微升, 100微升
克隆性 :
单克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
克隆名称 :
E83-77
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫组化-石蜡切片, 免疫组化-冰冻切片, 其他
文章摘录数: 64
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 人类; 1:1000; 图 2c
Liu Y, Zhang Y. Hsa_circ_0134111 promotes osteoarthritis progression by regulating miR-224-5p/CCL1 interaction. Aging (Albany NY). 2021;13:20383-20394 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 1e, 3f
Liu W, Long Q, Zhang W, Zeng D, Hu B, Liu S, et al. miRNA-221-3p derived from M2-polarized tumor-associated macrophage exosomes aggravates the growth and metastasis of osteosarcoma through SOCS3/JAK2/STAT3 axis. Aging (Albany NY). 2021;13:19760-19775 pubmed 出版商
  • 免疫印迹; 小鼠; 1:500; 图 2h
Hou Z, Chen J, Yang H, Hu X, Yang F. microRNA-26a shuttled by extracellular vesicles secreted from adipose-derived mesenchymal stem cells reduce neuronal damage through KLF9-mediated regulation of TRAF2/KLF2 axis. Adipocyte. 2021;10:378-393 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 图 s3a
  • 免疫细胞化学; 小鼠; 图 s4c, s5a
Okamura T, Hashimoto Y, Mori J, Yamaguchi M, Majima S, Senmaru T, et al. ILC2s Improve Glucose Metabolism Through the Control of Saturated Fatty Acid Absorption Within Visceral Fat. Front Immunol. 2021;12:669629 pubmed 出版商
  • 免疫印迹; 人类; 1:1500; 图 7a
Chen W, Song J, Liu S, Tang B, Shen L, Zhu J, et al. USP9X promotes apoptosis in cholangiocarcinoma by modulation expression of KIF1Bβ via deubiquitinating EGLN3. J Biomed Sci. 2021;28:44 pubmed 出版商
  • 免疫印迹; 人类; 1:2500; 图 1a
Matsui H, Ito J, Matsui N, Uechi T, Onodera O, Kakita A. Cytosolic dsDNA of mitochondrial origin induces cytotoxicity and neurodegeneration in cellular and zebrafish models of Parkinson's disease. Nat Commun. 2021;12:3101 pubmed 出版商
  • 免疫印迹; 人类; 1:5000; 图 5k
Ma Y, Shi B, Lu H, Xie P, Xin R, Wu Z, et al. MicroRNA-499 serves as a sensitizer for lung cancer cells to radiotherapy by inhibition of CK2α-mediated phosphorylation of p65. Mol Ther Oncolytics. 2021;21:171-182 pubmed 出版商
  • 免疫印迹; 大鼠; 1:500; 图 2h
Cheng J, Duan X, Fu X, Jiang Y, Yang P, Cao C, et al. RIP1 Perturbation Induces Chondrocyte Necroptosis and Promotes Osteoarthritis Pathogenesis via Targeting BMP7. Front Cell Dev Biol. 2021;9:638382 pubmed 出版商
  • 免疫印迹; 人类; 图 6c
Guo J, Zhu H, Li Q, Dong J, Xiong W, Yu K. SPRY4 suppresses proliferation and induces apoptosis of colorectal cancer cells by repressing oncogene EZH2. Aging (Albany NY). 2021;13:11665-11677 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 5p
Jin D, Guo J, Wu Y, Yang L, Wang X, Du J, et al. m6A demethylase ALKBH5 inhibits tumor growth and metastasis by reducing YTHDFs-mediated YAP expression and inhibiting miR-107/LATS2-mediated YAP activity in NSCLC. Mol Cancer. 2020;19:40 pubmed 出版商
  • 免疫印迹; 人类; 1:2000; 图 5e
Huang S, Zhang C, Sun C, Hou Y, Zhang Y, Tam N, et al. Obg-like ATPase 1 (OLA1) overexpression predicts poor prognosis and promotes tumor progression by regulating P21/CDK2 in hepatocellular carcinoma. Aging (Albany NY). 2020;12:3025-3041 pubmed 出版商
  • 免疫印迹; 人类; 1:500; 图 5a
Xu S, Zhan M, Jiang C, He M, Yang L, Shen H, et al. Genome-wide CRISPR screen identifies ELP5 as a determinant of gemcitabine sensitivity in gallbladder cancer. Nat Commun. 2019;10:5492 pubmed 出版商
  • 免疫印迹; 人类; 1:3000; 图 2b
Liu X, Huang J, Xie Y, Zhou Y, Wang R, Lou J. Napabucasin Attenuates Resistance of Breast Cancer Cells to Tamoxifen by Reducing Stem Cell-Like Properties. Med Sci Monit. 2019;25:8905-8912 pubmed 出版商
  • 免疫印迹; 人类; 1:5000; 图 3d
Li R, Guo M, Song L. PAS Domain Containing Repressor 1 (PASD1) Promotes Glioma Cell Proliferation Through Inhibiting Apoptosis In Vitro. Med Sci Monit. 2019;25:6955-6964 pubmed 出版商
  • 免疫印迹; 人类; 图 2d
Xu X, Tao Y, Niu Y, Wang Z, Zhang C, Yu Y, et al. miR-125a-5p inhibits tumorigenesis in hepatocellular carcinoma. Aging (Albany NY). 2019;11:7639-7662 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 9a
Wu K, Zou J, Lin C, Jie Z. MicroRNA-140-5p inhibits cell proliferation, migration and promotes cell apoptosis in gastric cancer through the negative regulation of THY1-mediated Notch signaling. Biosci Rep. 2019;: pubmed 出版商
  • 免疫印迹; 人类; 图 5b
Chen L, Yang G, Dong H. Everolimus Reverses Palbociclib Resistance in ER+ Human Breast Cancer Cells by Inhibiting Phosphatidylinositol 3-Kinase(PI3K)/Akt/Mammalian Target of Rapamycin (mTOR) Pathway. Med Sci Monit. 2019;25:77-86 pubmed 出版商
  • 其他; 人类; 图 4c
Ng P, Li J, Jeong K, Shao S, Chen H, Tsang Y, et al. Systematic Functional Annotation of Somatic Mutations in Cancer. Cancer Cell. 2018;33:450-462.e10 pubmed 出版商
  • 免疫印迹; 人类; 图 4c
Zhang Z, Huang A, Zhang A, Zhou C. HuR promotes breast cancer cell proliferation and survival via binding to CDK3 mRNA. Biomed Pharmacother. 2017;91:788-795 pubmed 出版商
  • 免疫印迹; 人类; 图 8a
Cao L, Zhang L, Zhao X, Zhang Y. A Hybrid Chalcone Combining the Trimethoxyphenyl and Isatinyl Groups Targets Multiple Oncogenic Proteins and Pathways in Hepatocellular Carcinoma Cells. PLoS ONE. 2016;11:e0161025 pubmed 出版商
  • 免疫印迹; 人类; 1:500; 图 s3d
Maynard J, Emmas S, Blé F, Barjat H, Lawrie E, Hancox U, et al. The use of (18)F-fluorodeoxyglucose positron emission tomography ((18)F-FDG PET) as a pathway-specific biomarker with AZD8186, a PI3K?/? inhibitor. EJNMMI Res. 2016;6:62 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 4c
Shen H, Zhao L, Feng X, Xu C, Li C, Niu Y. Lin28A activates androgen receptor via regulation of c-myc and promotes malignancy of ER-/Her2+ breast cancer. Oncotarget. 2016;7:60407-60418 pubmed 出版商
  • 免疫印迹; 人类; 1:500; 图 6
Zhao X, Wang J, Xiao L, Xu Q, Zhao E, Zheng X, et al. Effects of 17-AAG on the cell cycle and apoptosis of H446 cells and the associated mechanisms. Mol Med Rep. 2016;14:1067-74 pubmed 出版商
  • 免疫细胞化学; 人类; 1:100; 图 11
  • 免疫印迹; 人类; 1:1000; 图 9
Guo Y, Sun J, Ye J, Ma W, Yan H, Wang G. Saussurea tridactyla Sch. Bip.-derived polysaccharides and flavones reduce oxidative damage in ultraviolet B-irradiated HaCaT cells via a p38MAPK-independent mechanism. Drug Des Devel Ther. 2016;10:389-403 pubmed 出版商
  • 免疫组化; 小鼠; 图 2s1
Zylicz J, Dietmann S, Günesdogan U, Hackett J, Cougot D, Lee C, et al. Chromatin dynamics and the role of G9a in gene regulation and enhancer silencing during early mouse development. elife. 2015;4: pubmed 出版商
  • 免疫印迹; 人类; 图 3
Zuazua Villar P, Ganesh A, Phear G, Gagou M, Meuth M. Extensive RPA2 hyperphosphorylation promotes apoptosis in response to DNA replication stress in CHK1 inhibited cells. Nucleic Acids Res. 2015;43:9776-87 pubmed 出版商
  • 免疫印迹; 人类; 图 4
Dong L, Yu D, Wu N, Wang H, Niu J, Wang Y, et al. Echinacoside Induces Apoptosis in Human SW480 Colorectal Cancer Cells by Induction of Oxidative DNA Damages. Int J Mol Sci. 2015;16:14655-68 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 4b
Dai W, Wang F, Lu J, Xia Y, He L, Chen K, et al. By reducing hexokinase 2, resveratrol induces apoptosis in HCC cells addicted to aerobic glycolysis and inhibits tumor growth in mice. Oncotarget. 2015;6:13703-17 pubmed
  • 免疫细胞化学; 人类; 1:200; 图 4c
Zhang R, Wang R, Chen Q, Chang H. Inhibition of autophagy using 3-methyladenine increases cisplatin-induced apoptosis by increasing endoplasmic reticulum stress in U251 human glioma cells. Mol Med Rep. 2015;12:1727-32 pubmed 出版商
  • 免疫印迹; 人类; 1:1000
Lue L, Schmitz C, Serrano G, Sue L, Beach T, Walker D. TREM2 Protein Expression Changes Correlate with Alzheimer's Disease Neurodegenerative Pathologies in Post-Mortem Temporal Cortices. Brain Pathol. 2015;25:469-80 pubmed 出版商
  • 免疫印迹; 人类; 图 1
Wang W, Catto J, Meuth M. Differential response of normal and malignant urothelial cells to CHK1 and ATM inhibitors. Oncogene. 2015;34:2887-96 pubmed 出版商
Xiao C, Zhang W, Hua M, Chen H, Yang B, Wang Y, et al. TRIM27 interacts with Iκbα to promote the growth of human renal cancer cells through regulating the NF-κB pathway. BMC Cancer. 2021;21:841 pubmed 出版商
Zeng X, Jiang S, Ruan S, Guo Z, Guo J, Liu M, et al. MAPK4 silencing together with a PARP1 inhibitor as a combination therapy in triple‑negative breast cancer cells. Mol Med Rep. 2021;24: pubmed 出版商
Zhang M, Cheng K, Chen H, Tu J, Shen Y, Pang L, et al. LncRNA AK020546 protects against cardiac ischemia-reperfusion injury by sponging miR-350-3p. Aging (Albany NY). 2021;13:14219-14233 pubmed 出版商
Zhang C, Wang L, Shen Y. Circ_0004104 knockdown alleviates oxidized low-density lipoprotein-induced dysfunction in vascular endothelial cells through targeting miR-328-3p/TRIM14 axis in atherosclerosis. BMC Cardiovasc Disord. 2021;21:207 pubmed 出版商
Sun J, Wei S, Zhang Y, Li J. Protective Effects of Astragalus Polysaccharide on Sepsis-Induced Acute Kidney Injury. Anal Cell Pathol (Amst). 2021;2021:7178253 pubmed 出版商
Hu B, Yang X, Yang X, Sang X. LncRNA CYTOR affects the proliferation, cell cycle and apoptosis of hepatocellular carcinoma cells by regulating the miR-125b-5p/KIAA1522 axis. Aging (Albany NY). 2020;13:2626-2639 pubmed 出版商
Zhu X, Han J, Lan H, Lin Q, Wang Y, Sun X. A novel circular RNA hsa_circRNA_103809/miR-377-3p/GOT1 pathway regulates cisplatin-resistance in non-small cell lung cancer (NSCLC). BMC Cancer. 2020;20:1190 pubmed 出版商
Wang Y, Zhu S, Wei W, Tu Y, Chen C, Song J, et al. Interleukin-6 knockout reverses macrophage differentiation imbalance and alleviates cardiac dysfunction in aging mice. Aging (Albany NY). 2020;12:20184-20197 pubmed 出版商
Diao W, Guo Q, Zhu C, Song Y, Feng H, Cao Y, et al. USP18 promotes cell proliferation and suppressed apoptosis in cervical cancer cells via activating AKT signaling pathway. BMC Cancer. 2020;20:741 pubmed 出版商
Du H, Chen B, Jiao N, Liu Y, Sun S, Zhang Y. Elevated Glutathione Peroxidase 2 Expression Promotes Cisplatin Resistance in Lung Adenocarcinoma. Oxid Med Cell Longev. 2020;2020:7370157 pubmed 出版商
Bi Y, Fu Y, Wang S, Chen X, Cai X. Schizandrin A exerts anti-tumor effects on A375 cells by down-regulating H19. Braz J Med Biol Res. 2019;52:e8385 pubmed 出版商
Hidalgo A, Glass N, Ovchinnikov D, Yang S, Zhang X, Mazzone S, et al. Modelling ischemia-reperfusion injury (IRI) in vitro using metabolically matured induced pluripotent stem cell-derived cardiomyocytes. APL Bioeng. 2018;2:026102 pubmed 出版商
Sun H, Gao D. Propofol suppresses growth, migration and invasion of A549 cells by down-regulation of miR-372. BMC Cancer. 2018;18:1252 pubmed 出版商
Raz Y, Cohen N, Shani O, Bell R, Novitskiy S, Abramovitz L, et al. Bone marrow-derived fibroblasts are a functionally distinct stromal cell population in breast cancer. J Exp Med. 2018;215:3075-3093 pubmed 出版商
Tian M, Yang S, Yan X. Icariin reduces human colon carcinoma cell growth and metastasis by enhancing p53 activities. Braz J Med Biol Res. 2018;51:e7151 pubmed 出版商
Liu G, Zhang W. Long non-coding RNA HOTAIR promotes UVB-induced apoptosis and inflammatory injury by up-regulation of PKR in keratinocytes. Braz J Med Biol Res. 2018;51:e6896 pubmed 出版商
Lu H, Yan J, Jin P, Zheng G, Zhang H, Bai M, et al. Mechanism of MicroRNA-708 Targeting BAMBI in Cell Proliferation, Migration, and Apoptosis in Mice With Melanoma via the Wnt and TGF-β Signaling Pathways. Technol Cancer Res Treat. 2018;17:1533034618756784 pubmed 出版商
Tran L, Kichenadasse G, Butler L, Centenera M, Morel K, Ormsby R, et al. The Combination of Metformin and Valproic Acid Induces Synergistic Apoptosis in the Presence of p53 and Androgen Signaling in Prostate Cancer. Mol Cancer Ther. 2017;16:2689-2700 pubmed 出版商
Meisenberg C, Ashour M, El Shafie L, Liao C, Hodgson A, Pilborough A, et al. Epigenetic changes in histone acetylation underpin resistance to the topoisomerase I inhibitor irinotecan. Nucleic Acids Res. 2017;45:1159-1176 pubmed 出版商
Chan T, Hsu C, Pai V, Liao W, Huang S, Tan K, et al. Metronomic chemotherapy prevents therapy-induced stromal activation and induction of tumor-initiating cells. J Exp Med. 2016;213:2967-2988 pubmed
Hayakawa K, Esposito E, Wang X, Terasaki Y, Liu Y, Xing C, et al. Transfer of mitochondria from astrocytes to neurons after stroke. Nature. 2016;535:551-5 pubmed 出版商
Zhu Z, Cai W, Wang T, Ye H, Zhu Y, Chi L, et al. bFGF-Regulating MAPKs Are Involved in High Glucose-Mediated ROS Production and Delay of Vascular Endothelial Cell Migration. PLoS ONE. 2015;10:e0144495 pubmed 出版商
Guan Z, Wang X, Dong Y, Xu L, Zhu Z, Wang J, et al. dNTP deficiency induced by HU via inhibiting ribonucleotide reductase affects neural tube development. Toxicology. 2015;328:142-51 pubmed 出版商
Wang J, Feng J, Han J, Zhang B, Mao W. The molecular mechanisms of Tanshinone IIA on the apoptosis and arrest of human esophageal carcinoma cells. Biomed Res Int. 2014;2014:582730 pubmed 出版商
Gras B, Jacqueroud L, Wierinckx A, Lamblot C, Fauvet F, Lachuer J, et al. Snail family members unequally trigger EMT and thereby differ in their ability to promote the neoplastic transformation of mammary epithelial cells. PLoS ONE. 2014;9:e92254 pubmed 出版商
Augert A, Vindrieux D, Girard C, Le Calve B, Gras B, Ferrand M, et al. PLA2R1 kills cancer cells by inducing mitochondrial stress. Free Radic Biol Med. 2013;65:969-977 pubmed 出版商
Hosoda R, Kuno A, Hori Y, Ohtani K, Wakamiya N, Oohiro A, et al. Differential cell-protective function of two resveratrol (trans-3,5,4'-trihydroxystilbene) glucosides against oxidative stress. J Pharmacol Exp Ther. 2013;344:124-32 pubmed 出版商
Gagou M, Ganesh A, Thompson R, Phear G, Sanders C, Meuth M. Suppression of apoptosis by PIF1 helicase in human tumor cells. Cancer Res. 2011;71:4998-5008 pubmed 出版商
Aguzzi M, Fortugno P, Giampietri C, Ragone G, Capogrossi M, Facchiano A. Intracellular targets of RGDS peptide in melanoma cells. Mol Cancer. 2010;9:84 pubmed 出版商
Gagou M, Zuazua Villar P, Meuth M. Enhanced H2AX phosphorylation, DNA replication fork arrest, and cell death in the absence of Chk1. Mol Biol Cell. 2010;21:739-52 pubmed 出版商
Pupure J, Isajevs S, Skapare E, Rumaks J, Svirskis S, Svirina D, et al. Neuroprotective properties of mildronate, a mitochondria-targeted small molecule. Neurosci Lett. 2010;470:100-5 pubmed 出版商
Ottewell P, Woodward J, Lefley D, Evans C, Coleman R, Holen I. Anticancer mechanisms of doxorubicin and zoledronic acid in breast cancer tumor growth in bone. Mol Cancer Ther. 2009;8:2821-32 pubmed 出版商
Myers K, Gagou M, Zuazua Villar P, Rodriguez R, Meuth M. ATR and Chk1 suppress a caspase-3-dependent apoptotic response following DNA replication stress. PLoS Genet. 2009;5:e1000324 pubmed 出版商
产品信息
目录号 :
ab32042
ItemName :
抗活性的胱氨酸-天冬氨酸蛋白酶3抗体[E83-77]
类别 :
抗体
宿主 :
克隆性 :
单克隆
共轭标签 :
未共轭
克隆名称 :
E83-77
规格 :
10微升, 100微升
物种摘要 :
Hu
应用摘要 :
ICC/IF, IHC-Fr, WB
公司信息
艾博抗(上海)贸易有限公司
上海市浦东新区伽利略路338号5幢4层5401室
cn.technical@abcam.com
http://www.abcam.cn
400-628-6880 86-21-5110 5938
公司总部: 英国
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