Zhu X, Peng S, Wang L, Chen X, Feng C, Liu Y, et al. Identification of phosphoenolpyruvate carboxykinase 1 as a potential therapeutic target for pancreatic cancer. Cell Death Dis. 2021;12:918 pubmed 出版商

Kalogirou C, Linxweiler J, Schmucker P, Snaebjornsson M, Schmitz W, Wach S, et al. MiR-205-driven downregulation of cholesterol biosynthesis through SQLE-inhibition identifies therapeutic vulnerability in aggressive prostate cancer. Nat Commun. 2021;12:5066 pubmed 出版商

Kim Y, Lee J, Kim H, Jang J, Choung Y. Gap Junction-Mediated Intercellular Communication of cAMP Prevents CDDP-Induced Ototoxicity via cAMP/PKA/CREB Pathway. Int J Mol Sci. 2021;22: pubmed 出版商

Williams H, Wadey K, Frankow A, Blythe H, Forbes T, Johnson J, et al. Aneurysm severity is suppressed by deletion of CCN4. J Cell Commun Signal. 2021;15:421-432 pubmed 出版商

Lee J, Hsu Y, Li Y, Cheng S. Galectin-3 Inhibitors Suppress Anoikis Resistance and Invasive Capacity in Thyroid Cancer Cells. Int J Endocrinol. 2021;2021:5583491 pubmed 出版商

Cheng J, Duan X, Fu X, Jiang Y, Yang P, Cao C, et al. RIP1 Perturbation Induces Chondrocyte Necroptosis and Promotes Osteoarthritis Pathogenesis via Targeting BMP7. Front Cell Dev Biol. 2021;9:638382 pubmed 出版商

He S, Ma X, Zheng N, Wang G, Wang M, Xia W, et al. PRDM14 mediates chemosensitivity and glycolysis in drug‑resistant A549/cisplatin cells and their progenitor A549 human lung adenocarcinoma cells. Mol Med Rep. 2021;23: pubmed 出版商

Han B, Meng X, Wu P, Li Z, Li S, Zhang Y, et al. ATRX/EZH2 complex epigenetically regulates FADD/PARP1 axis, contributing to TMZ resistance in glioma. Theranostics. 2020;10:3351-3365 pubmed 出版商

Jiang L, Xu K, Li J, Zhou X, Xu L, Wu Z, et al. Nesfatin-1 suppresses interleukin-1β-induced inflammation, apoptosis, and cartilage matrix destruction in chondrocytes and ameliorates osteoarthritis in rats. Aging (Albany NY). 2020;12:1760-1777 pubmed 出版商

Li T, Li K, Zhang S, Wang Y, Xu Y, Cronin S, et al. Overexpression of apoptosis inducing factor aggravates hypoxic-ischemic brain injury in neonatal mice. Cell Death Dis. 2020;11:77 pubmed 出版商

Aldaz P, Otaegi Ugartemendia M, Sáenz Antoñanzas A, Garcia Puga M, Moreno Valladares M, Flores J, et al. SOX9 promotes tumor progression through the axis BMI1-p21CIP. Sci Rep. 2020;10:357 pubmed 出版商

Han Y, Wang Z, Sun S, Zhang Z, Liu J, Jin X, et al. Decreased DHRS2 expression is associated with HDACi resistance and poor prognosis in ovarian cancer. Epigenetics. 2019;:1-12 pubmed 出版商

Pietila M, Sahgal P, Peuhu E, Jäntti N, Paatero I, Närvä E, et al. SORLA regulates endosomal trafficking and oncogenic fitness of HER2. Nat Commun. 2019;10:2340 pubmed 出版商

Wu K, Zou J, Lin C, Jie Z. MicroRNA-140-5p inhibits cell proliferation, migration and promotes cell apoptosis in gastric cancer through the negative regulation of THY1-mediated Notch signaling. Biosci Rep. 2019;: pubmed 出版商

Liu X, Zhao P, Wang X, Wang L, Zhu Y, Song Y, et al. Celastrol mediates autophagy and apoptosis via the ROS/JNK and Akt/mTOR signaling pathways in glioma cells. J Exp Clin Cancer Res. 2019;38:184 pubmed 出版商

Chung H, Zou X, Bajar B, Brand V, Huo Y, Alcudia J, et al. A compact synthetic pathway rewires cancer signaling to therapeutic effector release. Science. 2019;364: pubmed 出版商

Chen L, Yang G, Dong H. Everolimus Reverses Palbociclib Resistance in ER+ Human Breast Cancer Cells by Inhibiting Phosphatidylinositol 3-Kinase(PI3K)/Akt/Mammalian Target of Rapamycin (mTOR) Pathway. Med Sci Monit. 2019;25:77-86 pubmed 出版商

Greenhough A, Bagley C, Heesom K, Gurevich D, Gay D, Bond M, et al. Cancer cell adaptation to hypoxia involves a HIF-GPRC5A-YAP axis. EMBO Mol Med. 2018;10: pubmed 出版商

Shao X, Lai D, Zhang L, Xu H. Induction of Autophagy and Apoptosis via PI3K/AKT/TOR Pathways by Azadirachtin A in Spodoptera litura Cells. Sci Rep. 2016;6:35482 pubmed 出版商

Yan Y, Xie M, Zhang L, Zhou X, Xie H, Zhou L, et al. Ras-related associated with diabetes gene acts as a suppressor and inhibits Warburg effect in hepatocellular carcinoma. Onco Targets Ther. 2016;9:3925-37 pubmed 出版商

Xue H, Yuan G, Guo X, Liu Q, Zhang J, Gao X, et al. A novel tumor-promoting mechanism of IL6 and the therapeutic efficacy of tocilizumab: Hypoxia-induced IL6 is a potent autophagy initiator in glioblastoma via the p-STAT3-MIR155-3p-CREBRF pathway. Autophagy. 2016;12:1129-52 pubmed 出版商

Song J, Wang Y, Teng M, Zhang S, Yin M, Lu J, et al. Cordyceps militaris induces tumor cell death via the caspase?dependent mitochondrial pathway in HepG2 and MCF?7 cells. Mol Med Rep. 2016;13:5132-40 pubmed 出版商

Zeng W, Liu Q, Chen Z, Wu X, Zhong Y, Wu J. Silencing of hERG1 Gene Inhibits Proliferation and Invasion, and Induces Apoptosis in Human Osteosarcoma Cells by Targeting the NF-?B Pathway. J Cancer. 2016;7:746-57 pubmed 出版商

Holmberg Olausson K, Elsir T, Moazemi Goudarzi K, Nistér M, Lindström M. NPM1 histone chaperone is upregulated in glioblastoma to promote cell survival and maintain nucleolar shape. Sci Rep. 2015;5:16495 pubmed 出版商

Skrzypek K, Kusienicka A, Szewczyk B, Adamus T, Lukasiewicz E, Miekus K, et al. Constitutive activation of MET signaling impairs myogenic differentiation of rhabdomyosarcoma and promotes its development and progression. Oncotarget. 2015;6:31378-98 pubmed 出版商

Zhang P, Yang X, Ma X, Ingram D, Lazar A, Torres K, et al. Antitumor effects of pharmacological EZH2 inhibition on malignant peripheral nerve sheath tumor through the miR-30a and KPNB1 pathway. Mol Cancer. 2015;14:55 pubmed 出版商

Papanikolaou V, Stefanou N, Dubos S, Papathanasiou I, Palianopoulou M, Valiakou V, et al. Synergy of leptin/STAT3 with HER2 receptor induces tamoxifen resistance in breast cancer cells through regulation of apoptosis-related genes. Cell Oncol (Dordr). 2015;38:155-64 pubmed 出版商

Steffensen M, Fenger C, Christensen J, Jørgensen C, Bassi M, Christensen J, et al. Suppressors of cytokine signaling 1 and 3 are upregulated in brain resident cells in response to virus-induced inflammation of the central nervous system via at least two distinctive pathways. J Virol. 2014;88:14090-104 pubmed 出版商

Hegde V, Vogel R, Feany M. Glia are critical for the neuropathology of complex I deficiency in Drosophila. Hum Mol Genet. 2014;23:4686-92 pubmed 出版商

Moon S, Lee H, Kim S, Hong J, Chun S, Lee H, et al. Inhibition of STAT3 enhances sensitivity to tamoxifen in tamoxifen-resistant breast cancer cells. BMC Cancer. 2021;21:931 pubmed 出版商

Cheng G, Liu Y, Liu L, Ruan H, Cao Q, Song Z, et al. LINC00160 mediates sunitinib resistance in renal cell carcinoma via SAA1 that is implicated in STAT3 activation and compound transportation. Aging (Albany NY). 2020;12:17459-17479 pubmed 出版商

Diao W, Guo Q, Zhu C, Song Y, Feng H, Cao Y, et al. USP18 promotes cell proliferation and suppressed apoptosis in cervical cancer cells via activating AKT signaling pathway. BMC Cancer. 2020;20:741 pubmed 出版商

Zhou F, Du C, Xu D, Lu J, Zhou L, Wu C, et al. Knockdown of ubiquitin‑specific protease 51 attenuates cisplatin resistance in lung cancer through ubiquitination of zinc‑finger E‑box binding homeobox 1. Mol Med Rep. 2020;22:1382-1390 pubmed 出版商

Fu D, Qin K, Yang S, Lu J, Lian H, Zhao D. Proper mechanical stress promotes femoral head recovery from steroid-induced osteonecrosis in rats through the OPG/RANK/RANKL system. BMC Musculoskelet Disord. 2020;21:281 pubmed 出版商

Qiu N, Xu X, He Y. LncRNA TUG1 alleviates sepsis-induced acute lung injury by targeting miR-34b-5p/GAB1. BMC Pulm Med. 2020;20:49 pubmed 出版商

Xu Q, Fang H, Zhao L, Zhang C, Zhang L, Tian B. Mechano growth factor attenuates mechanical overload-induced nucleus pulposus cell apoptosis through inhibiting the p38 MAPK pathway. Biosci Rep. 2019;: pubmed 出版商

Xu Y, Yang X, Gao D, Yang L, Miskimins K, Qian S. Dihomo-γ-linolenic acid inhibits xenograft tumor growth in mice bearing shRNA-transfected HCA-7 cells targeting delta-5-desaturase. BMC Cancer. 2018;18:1268 pubmed 出版商

Li Y, Gong Y, Ning X, Peng D, Liu L, He S, et al. Downregulation of CLDN7 due to promoter hypermethylation is associated with human clear cell renal cell carcinoma progression and poor prognosis. J Exp Clin Cancer Res. 2018;37:276 pubmed 出版商

Hirota T, Blakeley P, Sangrithi M, Mahadevaiah S, Encheva V, Snijders A, et al. SETDB1 Links the Meiotic DNA Damage Response to Sex Chromosome Silencing in Mice. Dev Cell. 2018;47:645-659.e6 pubmed 出版商

Gao F, Yu X, Meng R, Wang J, Jia L. STARD13 is positively correlated with good prognosis and enhances 5-FU sensitivity via suppressing cancer stemness in hepatocellular carcinoma cells. Onco Targets Ther. 2018;11:5371-5381 pubmed 出版商

Shukla R, Banerjee S, Tripathi Y. Antioxidant and Antiapoptotic effect of aqueous extract of Pueraria tuberosa (Roxb. Ex Willd.) DC. On streptozotocin-induced diabetic nephropathy in rats. BMC Complement Altern Med. 2018;18:156 pubmed 出版商

Zhang K, Chen J, Zhou H, Chen Y, Zhi Y, Zhang B, et al. PU.1/microRNA-142-3p targets ATG5/ATG16L1 to inactivate autophagy and sensitize hepatocellular carcinoma cells to sorafenib. Cell Death Dis. 2018;9:312 pubmed 出版商

Zhang Q, Yin Z, Zhang F, Cao K, Sun H. CTHRC1 mediates IL?1??induced apoptosis in chondrocytes via JNK1/2 signaling. Int J Mol Med. 2018;41:2270-2278 pubmed 出版商

Shen W, De Hoyos C, Sun H, Vickers T, Liang X, Crooke S. Acute hepatotoxicity of 2' fluoro-modified 5-10-5 gapmer phosphorothioate oligonucleotides in mice correlates with intracellular protein binding and the loss of DBHS proteins. Nucleic Acids Res. 2018;46:2204-2217 pubmed 出版商

Kolluri K, Alifrangis C, Kumar N, Ishii Y, Price S, Michaut M, et al. Loss of functional BAP1 augments sensitivity to TRAIL in cancer cells. elife. 2018;7: pubmed 出版商

Bhowmick S, D Mello V, Ponery N, Abdul Muneer P. Neurodegeneration and Sensorimotor Deficits in the Mouse Model of Traumatic Brain Injury. Brain Sci. 2018;8: pubmed 出版商

Zheng S, Koh X, Goh H, Rahmat S, Hwang L, Lane D. Inhibiting p53 Acetylation Reduces Cancer Chemotoxicity. Cancer Res. 2017;77:4342-4354 pubmed 出版商

Kollareddy M, Sherrard A, Park J, Szemes M, Gallacher K, Melegh Z, et al. The small molecule inhibitor YK-4-279 disrupts mitotic progression of neuroblastoma cells, overcomes drug resistance and synergizes with inhibitors of mitosis. Cancer Lett. 2017;403:74-85 pubmed 出版商

Li X, Kang Y, Roife D, Lee Y, Pratt M, Perez M, et al. Prolonged exposure to extracellular lumican restrains pancreatic adenocarcinoma growth. Oncogene. 2017;36:5432-5438 pubmed 出版商

Wang Y, Chen Y, Zhang X, Cai G, An S, Wang X, et al. Tricholoma matsutake Aqueous Extract Induces Hepatocellular Carcinoma Cell Apoptosis via Caspase-Dependent Mitochondrial Pathway. Biomed Res Int. 2016;2016:9014364 pubmed 出版商

Liu J, Shi H, Li X, Chen G, Larsson C, Lui W. miR‑223‑3p regulates cell growth and apoptosis via FBXW7 suggesting an oncogenic role in human testicular germ cell tumors. Int J Oncol. 2017;50:356-364 pubmed 出版商

Tornin J, Martinez Cruzado L, Santos L, Rodriguez A, N ez L, Oro P, et al. Inhibition of SP1 by the mithramycin analog EC-8042 efficiently targets tumor initiating cells in sarcoma. Oncotarget. 2016;7:30935-50 pubmed 出版商

Ganz M, Bukong T, Csak T, Saha B, Park J, Ambade A, et al. Progression of non-alcoholic steatosis to steatohepatitis and fibrosis parallels cumulative accumulation of danger signals that promote inflammation and liver tumors in a high fat-cholesterol-sugar diet model in mice. J Transl Med. 2015;13:193 pubmed 出版商

Tarin C, Fernández Laso V, Sastre C, Madrigal Matute J, Gomez M, Zaragoza C, et al. Tumor necrosis factor-like weak inducer of apoptosis or Fn14 deficiency reduce elastase perfusion-induced aortic abdominal aneurysm in mice. J Am Heart Assoc. 2014;3: pubmed 出版商

Aure M, Leivonen S, Fleischer T, Zhu Q, Overgaard J, Alsner J, et al. Individual and combined effects of DNA methylation and copy number alterations on miRNA expression in breast tumors. Genome Biol. 2013;14:R126 pubmed 出版商

Leivonen S, Sahlberg K, Mäkelä R, Due E, Kallioniemi O, Børresen Dale A, et al. High-throughput screens identify microRNAs essential for HER2 positive breast cancer cell growth. Mol Oncol. 2014;8:93-104 pubmed 出版商

Zhang P, Garnett J, Creighton C, Al Sannaa G, Igram D, Lazar A, et al. EZH2-miR-30d-KPNB1 pathway regulates malignant peripheral nerve sheath tumour cell survival and tumourigenesis. J Pathol. 2014;232:308-18 pubmed 出版商

Tahiri A, Leivonen S, Lüders T, Steinfeld I, Ragle Aure M, Geisler J, et al. Deregulation of cancer-related miRNAs is a common event in both benign and malignant human breast tumors. Carcinogenesis. 2014;35:76-85 pubmed 出版商

Sahlberg K, Hongisto V, Edgren H, Mäkelä R, Hellström K, Due E, et al. The HER2 amplicon includes several genes required for the growth and survival of HER2 positive breast cancer cells. Mol Oncol. 2013;7:392-401 pubmed 出版商

Mitra M, Kandalam M, Sundaram C, Verma R, Maheswari U, Swaminathan S, et al. Reversal of stathmin-mediated microtubule destabilization sensitizes retinoblastoma cells to a low dose of antimicrotubule agents: a novel synergistic therapeutic intervention. Invest Ophthalmol Vis Sci. 2011;52:5441-8 pubmed 出版商

Iljin K, Ketola K, Vainio P, Halonen P, Kohonen P, Fey V, et al. High-throughput cell-based screening of 4910 known drugs and drug-like small molecules identifies disulfiram as an inhibitor of prostate cancer cell growth. Clin Cancer Res. 2009;15:6070-8 pubmed 出版商

Rodrigues P, Limback D, McGinnis L, Plancha C, Albertini D. Multiple mechanisms of germ cell loss in the perinatal mouse ovary. Reproduction. 2009;137:709-20 pubmed 出版商