Guo E, Mao X, Wang X, Guo L, An C, Zhang C, et al. Alternatively spliced ANLN isoforms synergistically contribute to the progression of head and neck squamous cell carcinoma. Cell Death Dis. 2021;12:764 pubmed 出版商

Wu S, Xiao Y, Wei J, Xu X, Jin X, Hu X, et al. MYC suppresses STING-dependent innate immunity by transcriptionally upregulating DNMT1 in triple-negative breast cancer. J Immunother Cancer. 2021;9: pubmed 出版商

Shani O, Raz Y, Monteran L, Scharff Y, Levi Galibov O, Megides O, et al. Evolution of fibroblasts in the lung metastatic microenvironment is driven by stage-specific transcriptional plasticity. elife. 2021;10: pubmed 出版商

Zhao N, Wang F, Ahmed S, Liu K, Cathcart S, Dimaio D, et al. Androgen Receptor, Although Not a Specific Marker For, Is a Novel Target to Suppress Glioma Stem Cells as a Therapeutic Strategy for Glioblastoma. Front Oncol. 2021;11:616625 pubmed 出版商

Wang K, Ding Y, Xu C, Hao M, Li H, Ding L. Cldn-7 deficiency promotes experimental colitis and associated carcinogenesis by regulating intestinal epithelial integrity. Oncoimmunology. 2021;10:1923910 pubmed 出版商

Gusyatiner O, Bady P, Pham M, Lei Y, Park J, Daniel R, et al. BET inhibitors repress expression of interferon-stimulated genes and synergize with HDAC inhibitors in glioblastoma. Neuro Oncol. 2021;23:1680-1692 pubmed 出版商

Zhu X, Chen L, Huang B, Li X, Yang L, Hu X, et al. Efficacy and mechanism of the combination of PARP and CDK4/6 inhibitors in the treatment of triple-negative breast cancer. J Exp Clin Cancer Res. 2021;40:122 pubmed 出版商

Hirano M, Imai Y, Kaito Y, Murayama T, Sato K, Ishida T, et al. Small-molecule HDAC and Akt inhibitors suppress tumor growth and enhance immunotherapy in multiple myeloma. J Exp Clin Cancer Res. 2021;40:110 pubmed 出版商

Sewastianik T, Straubhaar J, Zhao J, Samur M, Adler K, Tanton H, et al. miR-15a/16-1 deletion in activated B cells promotes plasma cell and mature B-cell neoplasms. Blood. 2021;137:1905-1919 pubmed 出版商

Jiang Y, Han Q, Zhao H, Zhang J. Promotion of epithelial-mesenchymal transformation by hepatocellular carcinoma-educated macrophages through Wnt2b/β-catenin/c-Myc signaling and reprogramming glycolysis. J Exp Clin Cancer Res. 2021;40:13 pubmed 出版商

Xi L, Carroll T, Matos I, Luo J, Polak L, Pasolli H, et al. m6A RNA methylation impacts fate choices during skin morphogenesis. elife. 2020;9: pubmed 出版商

Vatapalli R, Sagar V, Rodriguez Y, Zhao J, Unno K, Pamarthy S, et al. Histone methyltransferase DOT1L coordinates AR and MYC stability in prostate cancer. Nat Commun. 2020;11:4153 pubmed 出版商

Gu J, Zhang Y, Wang X, Xiang J, Deng S, Wu D, et al. Matrine inhibits the growth of natural killer/T-cell lymphoma cells by modulating CaMKIIγ-c-Myc signaling pathway. BMC Complement Med Ther. 2020;20:214 pubmed 出版商

Sato K, Hikita H, Myojin Y, Fukumoto K, Murai K, Sakane S, et al. Hyperglycemia enhances pancreatic cancer progression accompanied by elevations in phosphorylated STAT3 and MYC levels. PLoS ONE. 2020;15:e0235573 pubmed 出版商

Li W, Zhang N, Jin C, Long M, Rajabi H, Yasumizu Y, et al. MUC1-C drives stemness in progression of colitis to colorectal cancer. JCI Insight. 2020;5: pubmed 出版商

Rübben A, Wahl R, Eggermann T, Dahl E, Ortiz Brüchle N, Cacchi C. Mutation analysis of multiple pilomatricomas in a patient with myotonic dystrophy type 1 suggests a DM1-associated hypermutation phenotype. PLoS ONE. 2020;15:e0230003 pubmed 出版商

Dragan M, Nguyen M, Guzman S, Goertzen C, Brackstone M, Dhillo W, et al. G protein-coupled kisspeptin receptor induces metabolic reprograming and tumorigenesis in estrogen receptor-negative breast cancer. Cell Death Dis. 2020;11:106 pubmed 出版商

Ballabio C, Anderle M, Gianesello M, Lago C, Miele E, Cardano M, et al. Modeling medulloblastoma in vivo and with human cerebellar organoids. Nat Commun. 2020;11:583 pubmed 出版商

Tang L, Li J, Fu W, Wu W, Xu J. Suppression of FADS1 induces ROS generation, cell cycle arrest, and apoptosis in melanocytes: implications for vitiligo. Aging (Albany NY). 2019;11:11829-11843 pubmed 出版商

Jiang K, Zhi X, Ma Y, Zhou L. Long non-coding RNA TOB1-AS1 modulates cell proliferation, apoptosis, migration and invasion through miR-23a/NEU1 axis via Wnt/b-catenin pathway in gastric cancer. Eur Rev Med Pharmacol Sci. 2019;23:9890-9899 pubmed 出版商

Liu Y, Jiang Q, Liu X, Lin X, Tang Z, Liu C, et al. Cinobufotalin powerfully reversed EBV-miR-BART22-induced cisplatin resistance via stimulating MAP2K4 to antagonize non-muscle myosin heavy chain IIA/glycogen synthase 3β/β-catenin signaling pathway. EBioMedicine. 2019;48:386-404 pubmed 出版商

Littler S, Sloss O, Geary B, Pierce A, Whetton A, Taylor S. Oncogenic MYC amplifies mitotic perturbations. Open Biol. 2019;9:190136 pubmed 出版商

Sanghvi V, Leibold J, Mina M, Mohan P, Berishaj M, Li Z, et al. The Oncogenic Action of NRF2 Depends on De-glycation by Fructosamine-3-Kinase. Cell. 2019;178:807-819.e21 pubmed 出版商

Hovestadt V, Smith K, Bihannic L, Filbin M, Shaw M, Baumgartner A, et al. Resolving medulloblastoma cellular architecture by single-cell genomics. Nature. 2019;572:74-79 pubmed 出版商

Merve A, Zhang X, Pomella N, Acquati S, Hoeck J, Dumas A, et al. c-MYC overexpression induces choroid plexus papillomas through a T-cell mediated inflammatory mechanism. Acta Neuropathol Commun. 2019;7:2 pubmed 出版商

Weissmiller A, Wang J, Lorey S, Howard G, Martinez E, Liu Q, et al. Inhibition of MYC by the SMARCB1 tumor suppressor. Nat Commun. 2019;10:2014 pubmed 出版商

Zhu Y, Shi C, Bruins L, Wang X, Riggs D, Porter B, et al. Identification of lenalidomide resistance pathways in myeloma and targeted resensitization using cereblon replacement, inhibition of STAT3 or targeting of IRF4. Blood Cancer J. 2019;9:19 pubmed 出版商

Haikala H, Anttila J, Marques E, Raatikainen T, Ilander M, Hakanen H, et al. Pharmacological reactivation of MYC-dependent apoptosis induces susceptibility to anti-PD-1 immunotherapy. Nat Commun. 2019;10:620 pubmed 出版商

Ji Q, Xu X, Kang L, Xu Y, Xiao J, Goodman S, et al. Hematopoietic PBX-interacting protein mediates cartilage degeneration during the pathogenesis of osteoarthritis. Nat Commun. 2019;10:313 pubmed 出版商

Yang F, Fang E, Mei H, Chen Y, Li H, Li D, et al. Cis-Acting circ-CTNNB1 Promotes β-Catenin Signaling and Cancer Progression via DDX3-Mediated Transactivation of YY1. Cancer Res. 2019;79:557-571 pubmed 出版商

Urtishak K, Wang L, Culjkovic Kraljacic B, Davenport J, Porazzi P, Vincent T, et al. Targeting EIF4E signaling with ribavirin in infant acute lymphoblastic leukemia. Oncogene. 2019;38:2241-2262 pubmed 出版商

Mastromina I, Verrier L, Silva J, Storey K, Dale J. Myc activity is required for maintenance of the neuromesodermal progenitor signalling network and for segmentation clock gene oscillations in mouse. Development. 2018;145: pubmed 出版商

Nakagawa M, Shaffer A, Ceribelli M, Zhang M, Wright G, Huang D, et al. Targeting the HTLV-I-Regulated BATF3/IRF4 Transcriptional Network in Adult T Cell Leukemia/Lymphoma. Cancer Cell. 2018;34:286-297.e10 pubmed 出版商

Weniger M, Tiacci E, Schneider S, Arnolds J, Rüschenbaum S, Duppach J, et al. Human CD30+ B cells represent a unique subset related to Hodgkin lymphoma cells. J Clin Invest. 2018;128:2996-3007 pubmed 出版商

Su R, Dong L, Li C, Nachtergaele S, Wunderlich M, Qing Y, et al. R-2HG Exhibits Anti-tumor Activity by Targeting FTO/m6A/MYC/CEBPA Signaling. Cell. 2018;172:90-105.e23 pubmed 出版商

Henry K, Dilling T, Abdel Atti D, Edwards K, Evans M, Lewis J. Noninvasive 89Zr-Transferrin PET Shows Improved Tumor Targeting Compared with 18F-FDG PET in MYC-Overexpressing Human Triple-Negative Breast Cancer. J Nucl Med. 2018;59:51-57 pubmed 出版商

Chong I, Aronson L, Bryant H, Gulati A, Campbell J, Elliott R, et al. Mapping genetic vulnerabilities reveals BTK as a novel therapeutic target in oesophageal cancer. Gut. 2018;67:1780-1792 pubmed 出版商

Hu J, Guan W, Liu P, Dai J, Tang K, Xiao H, et al. Endoglin Is Essential for the Maintenance of Self-Renewal and Chemoresistance in Renal Cancer Stem Cells. Stem Cell Reports. 2017;9:464-477 pubmed 出版商

Riemer P, Rydenfelt M, Marks M, van Eunen K, Thedieck K, Herrmann B, et al. Oncogenic β-catenin and PIK3CA instruct network states and cancer phenotypes in intestinal organoids. J Cell Biol. 2017;216:1567-1577 pubmed 出版商

Zhang Q, Zhang Y, Parsels J, Lohse I, Lawrence T, Pasca di Magliano M, et al. Fbxw7 Deletion Accelerates KrasG12D-Driven Pancreatic Tumorigenesis via Yap Accumulation. Neoplasia. 2016;18:666-673 pubmed 出版商

Weng S, Matsuura S, Mowery C, Stoner S, Lam K, Ran D, et al. Restoration of MYC-repressed targets mediates the negative effects of GM-CSF on RUNX1-ETO leukemogenicity. Leukemia. 2017;31:159-169 pubmed 出版商

Takagi Y, Shimada K, Shimada S, Sakamoto A, Naoe T, Nakamura S, et al. SPIB is a novel prognostic factor in diffuse large B-cell lymphoma that mediates apoptosis via the PI3K-AKT pathway. Cancer Sci. 2016;107:1270-80 pubmed 出版商

Zheng J, Huang X, Tan W, Yu D, Du Z, Chang J, et al. Pancreatic cancer risk variant in LINC00673 creates a miR-1231 binding site and interferes with PTPN11 degradation. Nat Genet. 2016;48:747-57 pubmed 出版商

Camarda R, Zhou A, Kohnz R, Balakrishnan S, Mahieu C, Anderton B, et al. Inhibition of fatty acid oxidation as a therapy for MYC-overexpressing triple-negative breast cancer. Nat Med. 2016;22:427-32 pubmed 出版商

Cattoglio C, Zhang E, Grubisic I, Chiba K, Fong Y, Tjian R. Functional and mechanistic studies of XPC DNA-repair complex as transcriptional coactivator in embryonic stem cells. Proc Natl Acad Sci U S A. 2015;112:E2317-26 pubmed 出版商

González Prieto R, Cuijpers S, Kumar R, Hendriks I, Vertegaal A. c-Myc is targeted to the proteasome for degradation in a SUMOylation-dependent manner, regulated by PIAS1, SENP7 and RNF4. Cell Cycle. 2015;14:1859-72 pubmed 出版商

Simeone P, Trerotola M, Urbanella A, Lattanzio R, Ciavardelli D, Di Giuseppe F, et al. A unique four-hub protein cluster associates to glioblastoma progression. PLoS ONE. 2014;9:e103030 pubmed 出版商

Wang R, Wang Y, Gao Z, Qu X. The comparative study of acetyl-11-keto-beta-boswellic acid (AKBA) and aspirin in the prevention of intestinal adenomatous polyposis in APC(Min/+) mice. Drug Discov Ther. 2014;8:25-32 pubmed

Zhang X, Shetty M, Clemente V, Linder S, Bazzaro M. Targeting Mitochondrial Metabolism in Clear Cell Carcinoma of the Ovaries. Int J Mol Sci. 2021;22: pubmed 出版商

Patel A, Yoo S, Kong R, Sato T, Sinha A, Karam S, et al. Prototypical oncogene family Myc defines unappreciated distinct lineage states of small cell lung cancer. Sci Adv. 2021;7: pubmed 出版商

Chen Y, Gao H, Xie W, Guo J, Fang Q, Zhao P, et al. Genomic and transcriptomic analysis of pituitary adenomas reveals the impacts of copy number variations on gene expression and clinical prognosis among prolactin-secreting subtype. Aging (Albany NY). 2020;13:1276-1293 pubmed 出版商

Lorenzo Martín L, Fernández Parejo N, Menacho Márquez M, Rodríguez Fdez S, Robles Valero J, Zumalave S, et al. VAV2 signaling promotes regenerative proliferation in both cutaneous and head and neck squamous cell carcinoma. Nat Commun. 2020;11:4788 pubmed 出版商

Wu S, Zhang X, Dong M, Yang Z, Zhang M, Chen Q. sATP‑binding cassette subfamily G member 2 enhances the multidrug resistance properties of human nasal natural killer/T cell lymphoma side population cells. Oncol Rep. 2020;44:1467-1478 pubmed 出版商

Nie Z, Guo C, Das S, Chow C, Batchelor E, Simons S, et al. Dissecting transcriptional amplification by MYC. elife. 2020;9: pubmed 出版商

Chao X, Yi L, Lan L, Wei H, Wei D. Long-term PM2.5 exposure increases the risk of non-small cell lung cancer (NSCLC) progression by enhancing interleukin-17a (IL-17a)-regulated proliferation and metastasis. Aging (Albany NY). 2020;12:11579-11602 pubmed 出版商

Zhang D, Hu Q, Liu X, Ji Y, Chao H, Liu Y, et al. Intron retention is a hallmark and spliceosome represents a therapeutic vulnerability in aggressive prostate cancer. Nat Commun. 2020;11:2089 pubmed 出版商

Tsai M, Huang C, Wei Y, Liu T, Lin M, Yi L, et al. Combined Chibby and β-Catenin Predicts Clinical Outcomes in Patients with Hepatocellular Carcinoma. Int J Mol Sci. 2020;21: pubmed 出版商

Rohrberg J, Van de Mark D, Amouzgar M, Lee J, Taileb M, Corella A, et al. MYC Dysregulates Mitosis, Revealing Cancer Vulnerabilities. Cell Rep. 2020;30:3368-3382.e7 pubmed 出版商

Wang W, Guo P, Chen M, Chen D, Cheng Y, He L. FOXM1/LINC00152 feedback loop regulates proliferation and apoptosis in rheumatoid arthritis fibroblast-like synoviocytes via Wnt/β-catenin signaling pathway. Biosci Rep. 2020;40: pubmed 出版商

Farrington C, Yuan E, Mazhar S, Izadmehr S, Hurst L, Allen Petersen B, et al. Protein phosphatase 2A activation as a therapeutic strategy for managing MYC-driven cancers. J Biol Chem. 2020;295:757-770 pubmed 出版商

Zhang H, Christensen C, Dries R, Oser M, Deng J, Diskin B, et al. CDK7 Inhibition Potentiates Genome Instability Triggering Anti-tumor Immunity in Small Cell Lung Cancer. Cancer Cell. 2019;: pubmed 出版商

Chan K, Robert F, Oertlin C, Kapeller Libermann D, Avizonis D, Gutierrez J, et al. eIF4A supports an oncogenic translation program in pancreatic ductal adenocarcinoma. Nat Commun. 2019;10:5151 pubmed 出版商

Wang W, Zhang L, Gao W, Zhang D, Zhao Z, Bao Y. miR‑489 promotes apoptosis and inhibits invasiveness of glioma cells by targeting PAK5/RAF1 signaling pathways. Oncol Rep. 2019;42:2390-2401 pubmed 出版商

Hao Y, Lafita Navarro M, Zacharias L, Borenstein Auerbach N, Kim M, Barnes S, et al. Induction of LEF1 by MYC activates the WNT pathway and maintains cell proliferation. Cell Commun Signal. 2019;17:129 pubmed 出版商

Seo J, Agarwal E, Chae Y, Lee Y, Garlick D, Storaci A, et al. Mitochondrial fission factor is a novel Myc-dependent regulator of mitochondrial permeability in cancer. EBioMedicine. 2019;48:353-363 pubmed 出版商

Yu M, Cui R, Huang Y, Luo Y, Qin S, Zhong M. Increased proton-sensing receptor GPR4 signalling promotes colorectal cancer progression by activating the hippo pathway. EBioMedicine. 2019;48:264-276 pubmed 出版商

Da Costa E, Armaos G, McInnes G, Beaudry A, Moquin Beaudry G, Bertrand Lehouillier V, et al. Heart failure drug proscillaridin A targets MYC overexpressing leukemia through global loss of lysine acetylation. J Exp Clin Cancer Res. 2019;38:251 pubmed 出版商

Parasido E, Avetian G, Naeem A, Graham G, Pishvaian M, Glasgow E, et al. The sustained induction of c-Myc drives nab-paclitaxel resistance in primary pancreatic ductal carcinoma cells. Mol Cancer Res. 2019;: pubmed 出版商

Nowak D, Katsenelson K, Watrud K, Chen M, Mathew G, D Andrea V, et al. The PHLPP2 phosphatase is a druggable driver of prostate cancer progression. J Cell Biol. 2019;218:1943-1957 pubmed 出版商

Zhang C, Zhu Q, Gu J, Chen S, Li Q, Ying L. Down-regulation of CCNE1 expression suppresses cell proliferation and sensitizes gastric carcinoma cells to Cisplatin. Biosci Rep. 2019;39: pubmed 出版商

Benchetrit H, Jaber M, Zayat V, Sebban S, Pushett A, Makedonski K, et al. Direct Induction of the Three Pre-implantation Blastocyst Cell Types from Fibroblasts. Cell Stem Cell. 2019;24:983-994.e7 pubmed 出版商

Hu J, Guan W, Yan L, Ye Z, Wu L, Xu H. Cancer Stem Cell Marker Endoglin (CD105) Induces Epithelial Mesenchymal Transition (EMT) but Not Metastasis in Clear Cell Renal Cell Carcinoma. Stem Cells Int. 2019;2019:9060152 pubmed 出版商

Baluapuri A, Hofstetter J, Dudvarski Stankovic N, Endres T, Bhandare P, Vos S, et al. MYC Recruits SPT5 to RNA Polymerase II to Promote Processive Transcription Elongation. Mol Cell. 2019;74:674-687.e11 pubmed 出版商

Pillay N, Tighe A, Nelson L, Littler S, Coulson Gilmer C, Bah N, et al. DNA Replication Vulnerabilities Render Ovarian Cancer Cells Sensitive to Poly(ADP-Ribose) Glycohydrolase Inhibitors. Cancer Cell. 2019;35:519-533.e8 pubmed 出版商

Dong L, Reljic B, Cheung J, Ng E, Lindqvist L, Elefanty A, et al. In the absence of apoptosis, myeloid cells arrest when deprived of growth factor, but remain viable by consuming extracellular glucose. Cell Death Differ. 2019;: pubmed 出版商

He J, Deng L, Liu H, Chen T, Chen S, Xia S, et al. BCL2L10/BECN1 modulates hepatoma cells autophagy by regulating PI3K/AKT signaling pathway. Aging (Albany NY). 2019;11:350-370 pubmed 出版商

Annunziato S, de Ruiter J, Henneman L, Brambillasca C, Lutz C, Vaillant F, et al. Comparative oncogenomics identifies combinations of driver genes and drug targets in BRCA1-mutated breast cancer. Nat Commun. 2019;10:397 pubmed 出版商

Santoro A, Vlachou T, Luzi L, Melloni G, Mazzarella L, D Elia E, et al. p53 Loss in Breast Cancer Leads to Myc Activation, Increased Cell Plasticity, and Expression of a Mitotic Signature with Prognostic Value. Cell Rep. 2019;26:624-638.e8 pubmed 出版商

LI Y, Du L, Wang J, Vega R, Lee T, Miao Y, et al. Allosteric Inhibition of Ubiquitin-like Modifications by a Class of Inhibitor of SUMO-Activating Enzyme. Cell Chem Biol. 2019;26:278-288.e6 pubmed 出版商

Moon S, Huang C, Houlihan S, Regunath K, Freed Pastor W, Morris J, et al. p53 Represses the Mevalonate Pathway to Mediate Tumor Suppression. Cell. 2019;176:564-580.e19 pubmed 出版商

Sun W, Kang T, Wang Y, Sun J, Li C, Liu H, et al. Long noncoding RNA OIP5-AS1 targets Wnt-7b to affect glioma progression via modulation of miR-410. Biosci Rep. 2019;39: pubmed 出版商

Fu X, Zhang X, Yang H, Xu X, Hu Z, Yan J, et al. CUDC-907 displays potent antitumor activity against human pancreatic adenocarcinoma in vitro and in vivo through inhibition of HDAC6 to downregulate c-Myc expression. Acta Pharmacol Sin. 2019;40:677-688 pubmed 出版商

Somerville T, Xu Y, Miyabayashi K, Tiriac H, Cleary C, Maia Silva D, et al. TP63-Mediated Enhancer Reprogramming Drives the Squamous Subtype of Pancreatic Ductal Adenocarcinoma. Cell Rep. 2018;25:1741-1755.e7 pubmed 出版商

Zeng M, Kwiatkowski N, Zhang T, Nabet B, Xu M, Liang Y, et al. Targeting MYC dependency in ovarian cancer through inhibition of CDK7 and CDK12/13. elife. 2018;7: pubmed 出版商

Zhang X, Xu Y, Qian Z, Zheng W, Wu Q, Chen Y, et al. circRNA_104075 stimulates YAP-dependent tumorigenesis through the regulation of HNF4a and may serve as a diagnostic marker in hepatocellular carcinoma. Cell Death Dis. 2018;9:1091 pubmed 出版商

Wang S, Zheng Y, He Z, Zhou W, Cheng Y, Zhang C. SH2B1 promotes NSCLC cell proliferation through PI3K/Akt/mTOR signaling cascade. Cancer Cell Int. 2018;18:132 pubmed 出版商

Yakulov T, Todkar A, Slanchev K, Wiegel J, Bona A, Groß M, et al. CXCL12 and MYC control energy metabolism to support adaptive responses after kidney injury. Nat Commun. 2018;9:3660 pubmed 出版商

Mair R, Wright A, Ros S, Hu D, Booth T, Kreis F, et al. Metabolic Imaging Detects Low Levels of Glycolytic Activity That Vary with Levels of c-Myc Expression in Patient-Derived Xenograft Models of Glioblastoma. Cancer Res. 2018;78:5408-5418 pubmed 出版商

Ye Z, Ayer D. Ras Suppresses TXNIP Expression by Restricting Ribosome Translocation. Mol Cell Biol. 2018;38: pubmed 出版商

Allan L, Skowyra A, Rogers K, Zeller D, Clarke P. Atypical APC/C-dependent degradation of Mcl-1 provides an apoptotic timer during mitotic arrest. EMBO J. 2018;37: pubmed 出版商

Weltner J, Balboa D, Katayama S, Bespalov M, Krjutskov K, Jouhilahti E, et al. Human pluripotent reprogramming with CRISPR activators. Nat Commun. 2018;9:2643 pubmed 出版商

Nie X, Zheng J, Ricupero C, He L, Jiao K, Mao J. mTOR acts as a pivotal signaling hub for neural crest cells during craniofacial development. PLoS Genet. 2018;14:e1007491 pubmed 出版商

Gollavilli P, Pawar A, Wilder Romans K, Natesan R, Engelke C, Dommeti V, et al. EWS/ETS-Driven Ewing Sarcoma Requires BET Bromodomain Proteins. Cancer Res. 2018;78:4760-4773 pubmed 出版商

LI Y, Du L, Aldana Masangkay G, Wang X, Urak R, Forman S, et al. Regulation of miR-34b/c-targeted gene expression program by SUMOylation. Nucleic Acids Res. 2018;: pubmed 出版商

Cai J, Song X, Wang W, Watnick T, Pei Y, Qian F, et al. A RhoA-YAP-c-Myc signaling axis promotes the development of polycystic kidney disease. Genes Dev. 2018;32:781-793 pubmed 出版商

Chau K, Shannon M, Fame R, Fonseca E, Mullan H, Johnson M, et al. Downregulation of ribosome biogenesis during early forebrain development. elife. 2018;7: pubmed 出版商

Brandt L, Albers J, Hejhal T, Pfundstein S, Gonçalves A, Catalano A, et al. Mouse genetic background influences whether HrasG12V expression plus Cdkn2a knockdown causes angiosarcoma or undifferentiated pleomorphic sarcoma. Oncotarget. 2018;9:19753-19766 pubmed 出版商

Ji F, Zhang Z, Zhang Y, Shen S, Cao Q, Zhang L, et al. Low expression of c-Myc protein predicts poor outcomes in patients with hepatocellular carcinoma after resection. BMC Cancer. 2018;18:460 pubmed 出版商

Sun M, Sun L, Sun D, Zhang C, Li M. Targeted delivery of immuno-RNase may improve cancer therapy. Cancer Cell Int. 2018;18:58 pubmed 出版商

Hirth C, Dos Santos A, de Cerqueira J, Jamacaru F, da Cunha M, Dornelas C. PanCD44 Immunohistochemical Evaluation in Prostatectomies from Patients with Adenocarcinoma. Biomed Res Int. 2018;2018:2061268 pubmed 出版商

Zhang L, Zhou H, Li X, Vartuli R, Rowse M, Xing Y, et al. Eya3 partners with PP2A to induce c-Myc stabilization and tumor progression. Nat Commun. 2018;9:1047 pubmed 出版商

Mitchell S, Roy K, Zangle T, Hoffmann A. Nongenetic origins of cell-to-cell variability in B lymphocyte proliferation. Proc Natl Acad Sci U S A. 2018;115:E2888-E2897 pubmed 出版商

Zhao N, Cao J, Xu L, Tang Q, Dobrolecki L, Lv X, et al. Pharmacological targeting of MYC-regulated IRE1/XBP1 pathway suppresses MYC-driven breast cancer. J Clin Invest. 2018;128:1283-1299 pubmed 出版商

Xie H, Tang C, Song J, Mancuso A, Del Valle J, Cao J, et al. IRE1α RNase-dependent lipid homeostasis promotes survival in Myc-transformed cancers. J Clin Invest. 2018;128:1300-1316 pubmed 出版商

Akiyama T, Sato S, Chikazawa Nohtomi N, Soma A, Kimura H, Wakabayashi S, et al. Efficient differentiation of human pluripotent stem cells into skeletal muscle cells by combining RNA-based MYOD1-expression and POU5F1-silencing. Sci Rep. 2018;8:1189 pubmed 出版商

Liao P, Zeng S, Zhou X, Chen T, Zhou F, Cao B, et al. Mutant p53 Gains Its Function via c-Myc Activation upon CDK4 Phosphorylation at Serine 249 and Consequent PIN1 Binding. Mol Cell. 2017;68:1134-1146.e6 pubmed 出版商

Mishra P, Tang W, Putluri V, Dorsey T, Jin F, Wang F, et al. ADHFE1 is a breast cancer oncogene and induces metabolic reprogramming. J Clin Invest. 2018;128:323-340 pubmed 出版商

Monteverde T, Tait Mulder J, Hedley A, Knight J, Sansom O, Murphy D. Calcium signalling links MYC to NUAK1. Oncogene. 2017;: pubmed 出版商

Porter J, Fisher B, Baranello L, Liu J, Kambach D, Nie Z, et al. Global Inhibition with Specific Activation: How p53 and MYC Redistribute the Transcriptome in the DNA Double-Strand Break Response. Mol Cell. 2017;67:1013-1025.e9 pubmed 出版商

Chan K, Zengerle M, Testa A, Ciulli A. Impact of Target Warhead and Linkage Vector on Inducing Protein Degradation: Comparison of Bromodomain and Extra-Terminal (BET) Degraders Derived from Triazolodiazepine (JQ1) and Tetrahydroquinoline (I-BET726) BET Inhibitor Scaffolds. J Med Chem. 2018;61:504-513 pubmed 出版商

Yu P, Wilhelm K, Dubrac A, Tung J, Alves T, Fang J, et al. FGF-dependent metabolic control of vascular development. Nature. 2017;545:224-228 pubmed 出版商

Yuan H, Krawczyk E, Blancato J, Albanese C, Zhou D, Wang N, et al. HPV positive neuroendocrine cervical cancer cells are dependent on Myc but not E6/E7 viral oncogenes. Sci Rep. 2017;7:45617 pubmed 出版商

Enomoto K, Zhu X, Park S, Zhao L, Zhu Y, Willingham M, et al. Targeting MYC as a Therapeutic Intervention for Anaplastic Thyroid Cancer. J Clin Endocrinol Metab. 2017;102:2268-2280 pubmed 出版商

Altman B, Hsieh A, Gouw A, Dang C. Correspondence: Oncogenic MYC persistently upregulates the molecular clock component REV-ERB?. Nat Commun. 2017;8:14862 pubmed 出版商

Hogg S, Vervoort S, Deswal S, Ott C, Li J, Cluse L, et al. BET-Bromodomain Inhibitors Engage the Host Immune System and Regulate Expression of the Immune Checkpoint Ligand PD-L1. Cell Rep. 2017;18:2162-2174 pubmed 出版商

Malchenko S, Sredni S, Bi Y, Margaryan N, Boyineni J, Mohanam I, et al. Stabilization of HIF-1α and HIF-2α, up-regulation of MYCC and accumulation of stabilized p53 constitute hallmarks of CNS-PNET animal model. PLoS ONE. 2017;12:e0173106 pubmed 出版商

Chen M, Nowak D, Narula N, Robinson B, Watrud K, Ambrico A, et al. The nuclear transport receptor Importin-11 is a tumor suppressor that maintains PTEN protein. J Cell Biol. 2017;216:641-656 pubmed 出版商

Yahiaoui A, Meadows S, Sorensen R, Cui Z, Keegan K, Brockett R, et al. PI3Kδ inhibitor idelalisib in combination with BTK inhibitor ONO/GS-4059 in diffuse large B cell lymphoma with acquired resistance to PI3Kδ and BTK inhibitors. PLoS ONE. 2017;12:e0171221 pubmed 出版商

Marion R, Lopez de Silanes I, Mosteiro L, Gamache B, Abad M, Guerra C, et al. Common Telomere Changes during In Vivo Reprogramming and Early Stages of Tumorigenesis. Stem Cell Reports. 2017;8:460-475 pubmed 出版商

Yang C, Zhang S, Li J, Yang B, Ouyang W, Mei Z, et al. MicroRNA-320 regulates the radiosensitivity of cervical cancer cells C33AR by targeting ?-catenin. Oncol Lett. 2016;12:4983-4990 pubmed 出版商

Zhu J, Wang P, Yu Z, Lai W, Cao Y, Huang P, et al. Advanced glycosylation end product promotes forkhead box O1 and inhibits Wnt pathway to suppress capacities of epidermal stem cells. Am J Transl Res. 2016;8:5569-5579 pubmed

Chen Z, Tang C, Zhu Y, Xie M, He D, Pan Q, et al. TrpC5 regulates differentiation through the Ca2+/Wnt5a signalling pathway in colorectal cancer. Clin Sci (Lond). 2017;131:227-237 pubmed 出版商

Nowacka J, Baumgartner C, Pelorosso C, Roth M, Zuber J, Baccarini M. MEK1 is required for the development of NRAS-driven leukemia. Oncotarget. 2016;7:80113-80130 pubmed 出版商

Bond C, McKeone D, Kalimutho M, Bettington M, Pearson S, Dumenil T, et al. RNF43 and ZNRF3 are commonly altered in serrated pathway colorectal tumorigenesis. Oncotarget. 2016;7:70589-70600 pubmed 出版商

Soon G, Ow G, Chan H, Ng S, Wang S. Primary cardiac diffuse large B-cell lymphoma in immunocompetent patients: clinical, histologic, immunophenotypic, and genotypic features of 3 cases. Ann Diagn Pathol. 2016;24:40-6 pubmed 出版商

D Andrea A, Gritti I, Nicoli P, Giorgio M, Doni M, Conti A, et al. The mitochondrial translation machinery as a therapeutic target in Myc-driven lymphomas. Oncotarget. 2016;7:72415-72430 pubmed 出版商

Shen H, Zhao L, Feng X, Xu C, Li C, Niu Y. Lin28A activates androgen receptor via regulation of c-myc and promotes malignancy of ER-/Her2+ breast cancer. Oncotarget. 2016;7:60407-60418 pubmed 出版商

Shi X, Mihaylova V, Kuruvilla L, Chen F, Viviano S, Baldassarre M, et al. Loss of TRIM33 causes resistance to BET bromodomain inhibitors through MYC- and TGF-?-dependent mechanisms. Proc Natl Acad Sci U S A. 2016;113:E4558-66 pubmed 出版商

Wu Y, Bai J, Hong L, Liu C, Yu S, Yu G, et al. Low expression of secreted frizzled-related protein 2 and nuclear accumulation of ?-catenin in aggressive nonfunctioning pituitary adenoma. Oncol Lett. 2016;12:199-206 pubmed

Raina K, Lu J, Qian Y, Altieri M, Gordon D, Rossi A, et al. PROTAC-induced BET protein degradation as a therapy for castration-resistant prostate cancer. Proc Natl Acad Sci U S A. 2016;113:7124-9 pubmed 出版商

Kress T, Pellanda P, Pellegrinet L, Bianchi V, Nicoli P, Doni M, et al. Identification of MYC-Dependent Transcriptional Programs in Oncogene-Addicted Liver Tumors. Cancer Res. 2016;76:3463-72 pubmed 出版商

Swetzig W, Wang J, Das G. Estrogen receptor alpha (ERα/ESR1) mediates the p53-independent overexpression of MDM4/MDMX and MDM2 in human breast cancer. Oncotarget. 2016;7:16049-69 pubmed 出版商

Li X, Wu J, Li Q, Shigemura K, Chung L, Huang W. SREBP-2 promotes stem cell-like properties and metastasis by transcriptional activation of c-Myc in prostate cancer. Oncotarget. 2016;7:12869-84 pubmed 出版商

Franco M, Panas M, Marino N, Lee M, Buchholz K, Kelly F, et al. A Novel Secreted Protein, MYR1, Is Central to Toxoplasma's Manipulation of Host Cells. MBio. 2016;7:e02231-15 pubmed 出版商

Nakazawa M, Eisinger Mathason T, Sadri N, Ochocki J, Gade T, Amin R, et al. Epigenetic re-expression of HIF-2α suppresses soft tissue sarcoma growth. Nat Commun. 2016;7:10539 pubmed 出版商

Itkonen H, Gorad S, Duveau D, Martin S, Barkovskaya A, Bathen T, et al. Inhibition of O-GlcNAc transferase activity reprograms prostate cancer cell metabolism. Oncotarget. 2016;7:12464-76 pubmed 出版商

Chung S, Moon H, Kim D, Cho K, Ju H, Kim D, et al. Development of a transgenic mouse model of hepatocellular carcinoma with a liver fibrosis background. BMC Gastroenterol. 2016;16:13 pubmed 出版商

Silva M, Matheus W, Garcia P, Stopiglia R, Billis A, Ferreira U, et al. Characterization of reactive stroma in prostate cancer: involvement of growth factors, metalloproteinase matrix, sexual hormones receptors and prostatic stem cells. Int Braz J Urol. 2015;41:849-58 pubmed 出版商

Siegfried J, Lin Y, Diergaarde B, Lin H, Dacic S, Pennathur A, et al. Expression of PAM50 Genes in Lung Cancer: Evidence that Interactions between Hormone Receptors and HER2/HER3 Contribute to Poor Outcome. Neoplasia. 2015;17:817-25 pubmed 出版商

Monaghan M, Linneweh M, Liebscher S, Van Handel B, Layland S, Schenke Layland K. Endocardial-to-mesenchymal transformation and mesenchymal cell colonization at the onset of human cardiac valve development. Development. 2016;143:473-82 pubmed 出版商

Alexandrova S, Kalkan T, Humphreys P, Riddell A, Scognamiglio R, Trumpp A, et al. Selection and dynamics of embryonic stem cell integration into early mouse embryos. Development. 2016;143:24-34 pubmed 出版商

Pai P, Rachagani S, Lakshmanan I, Macha M, Sheinin Y, Smith L, et al. The canonical Wnt pathway regulates the metastasis-promoting mucin MUC4 in pancreatic ductal adenocarcinoma. Mol Oncol. 2016;10:224-39 pubmed 出版商

Chen J, Wang C, Lan W, Huang C, Lin M, Wang Z, et al. Gliotoxin Inhibits Proliferation and Induces Apoptosis in Colorectal Cancer Cells. Mar Drugs. 2015;13:6259-73 pubmed 出版商

Lee K, Kwak Y, Nam K, Kim D, Kang S, Choe G, et al. c-MYC Copy-Number Gain Is an Independent Prognostic Factor in Patients with Colorectal Cancer. PLoS ONE. 2015;10:e0139727 pubmed 出版商

Amaya C, Bryan B. Enrichment of the embryonic stem cell reprogramming factors Oct4, Nanog, Myc, and Sox2 in benign and malignant vascular tumors. BMC Clin Pathol. 2015;15:18 pubmed 出版商

Zou Y, Yang J, Jiang D. Resveratrol inhibits canonical Wnt signaling in human MG-63 osteosarcoma cells. Mol Med Rep. 2015;12:7221-6 pubmed 出版商

Kim S, Yang W, Min Y, Ko Y, Yoon S. The role of the polycomb repressive complex pathway in T and NK cell lymphoma: biological and prognostic implications. Tumour Biol. 2016;37:2037-47 pubmed 出版商

Boudjadi S, Carrier J, Groulx J, Beaulieu J. Integrin α1β1 expression is controlled by c-MYC in colorectal cancer cells. Oncogene. 2016;35:1671-8 pubmed 出版商

Barfeld S, Fazli L, Persson M, Marjavaara L, Urbanucci A, Kaukoniemi K, et al. Myc-dependent purine biosynthesis affects nucleolar stress and therapy response in prostate cancer. Oncotarget. 2015;6:12587-602 pubmed

Fu Q, Chen Z, Gong X, Cai Y, Chen Y, Ma X, et al. β-Catenin expression is regulated by an IRES-dependent mechanism and stimulated by paclitaxel in human ovarian cancer cells. Biochem Biophys Res Commun. 2015;461:21-7 pubmed 出版商

Chang B, Choi Y, Kim J. Collagen complexes increase the efficiency of iPS cells generated using fibroblasts from adult mice. J Reprod Dev. 2015;61:145-53 pubmed 出版商

Rogler A, Kendziorra E, Giedl J, Stoehr C, Taubert H, Goebell P, et al. Functional analyses and prognostic significance of SFRP1 expression in bladder cancer. J Cancer Res Clin Oncol. 2015;141:1779-90 pubmed 出版商

Tran D, Verma K, Ward K, Diaz D, Kataria E, Torabi A, et al. Functional genomics analysis reveals a MYC signature associated with a poor clinical prognosis in liposarcomas. Am J Pathol. 2015;185:717-28 pubmed 出版商

Huang S, Zou X, Zhu J, Fu Y, Lin Q, Liang Y, et al. Attenuation of microRNA-16 derepresses the cyclins D1, D2 and E1 to provoke cardiomyocyte hypertrophy. J Cell Mol Med. 2015;19:608-19 pubmed 出版商

Garbe J, Vrba L, Sputova K, Fuchs L, Novak P, Brothman A, et al. Immortalization of normal human mammary epithelial cells in two steps by direct targeting of senescence barriers does not require gross genomic alterations. Cell Cycle. 2014;13:3423-35 pubmed 出版商

Wiegering A, Korb D, Thalheimer A, Kämmerer U, Allmanritter J, Matthes N, et al. E7080 (lenvatinib), a multi-targeted tyrosine kinase inhibitor, demonstrates antitumor activities against colorectal cancer xenografts. Neoplasia. 2014;16:972-81 pubmed 出版商

Guo L, Shen Y, Zhao X, Guo L, Yu Z, Wang D, et al. Curcumin combined with oxaliplatin effectively suppress colorectal carcinoma in vivo through inducing apoptosis. Phytother Res. 2015;29:357-65 pubmed 出版商

Shinojima N, Nakamura H, Tasaki M, Kameno K, Anai S, Iyama K, et al. A patient with medulloblastoma in its early developmental stage. J Neurosurg Pediatr. 2014;14:615-20 pubmed 出版商

Popovic R, Martinez Garcia E, Giannopoulou E, Zhang Q, Zhang Q, Ezponda T, et al. Histone methyltransferase MMSET/NSD2 alters EZH2 binding and reprograms the myeloma epigenome through global and focal changes in H3K36 and H3K27 methylation. PLoS Genet. 2014;10:e1004566 pubmed 出版商

Diefenbacher M, Popov N, Blake S, Schülein Völk C, Nye E, Spencer Dene B, et al. The deubiquitinase USP28 controls intestinal homeostasis and promotes colorectal cancer. J Clin Invest. 2014;124:3407-18 pubmed 出版商

Kim J, Roberts J, Bingman W, Shao L, Wang J, Ittmann M, et al. The prostate cancer TMPRSS2:ERG fusion synergizes with the vitamin D receptor (VDR) to induce CYP24A1 expression-limiting VDR signaling. Endocrinology. 2014;155:3262-73 pubmed 出版商

Van Der Meer R, Song H, Park S, Abdulkadir S, Roh M. RNAi screen identifies a synthetic lethal interaction between PIM1 overexpression and PLK1 inhibition. Clin Cancer Res. 2014;20:3211-21 pubmed 出版商

Wang B, Li J, Ye Z, Li Z, Wu X. N-myc downstream regulated gene 1 acts as a tumor suppressor in ovarian cancer. Oncol Rep. 2014;31:2279-85 pubmed 出版商

Sanz Moreno A, Fuhrmann D, Wolf E, von Eyss B, Eilers M, Elsässer H. Miz1 deficiency in the mammary gland causes a lactation defect by attenuated Stat5 expression and phosphorylation. PLoS ONE. 2014;9:e89187 pubmed 出版商

Toon C, Chou A, Clarkson A, Desilva K, Houang M, Chan J, et al. Immunohistochemistry for myc predicts survival in colorectal cancer. PLoS ONE. 2014;9:e87456 pubmed 出版商

Zuo P, Ma Y, Huang Y, Ye F, Wang P, Wang X, et al. High GMFG expression correlates with poor prognosis and promotes cell migration and invasion in epithelial ovarian cancer. Gynecol Oncol. 2014;132:745-51 pubmed 出版商

Qin Y, Lu Y, Wang R, Li W, Qu X. SL1122-37, a novel derivative of sorafenib, has greater effects than sorafenib on the inhibition of human hepatocellular carcinoma (HCC) growth and prevention of angiogenesis. Biosci Trends. 2013;7:237-44 pubmed

Sanchez Arévalo Lobo V, Doni M, Verrecchia A, Sanulli S, Fagà G, Piontini A, et al. Dual regulation of Myc by Abl. Oncogene. 2013;32:5261-71 pubmed 出版商

Marzi M, Puggioni E, Dall olio V, Bucci G, Bernard L, Bianchi F, et al. Differentiation-associated microRNAs antagonize the Rb-E2F pathway to restrict proliferation. J Cell Biol. 2012;199:77-95 pubmed 出版商

Hollern D, Yuwanita I, Andrechek E. A mouse model with T58A mutations in Myc reduces the dependence on KRas mutations and has similarities to claudin-low human breast cancer. Oncogene. 2013;32:1296-304 pubmed 出版商

Neff T, Sinha A, Kluk M, Zhu N, Khattab M, Stein L, et al. Polycomb repressive complex 2 is required for MLL-AF9 leukemia. Proc Natl Acad Sci U S A. 2012;109:5028-33 pubmed 出版商

Kim C, Vo M, Kim H, Lee H, Yoon N, Lee B, et al. Ectopic over-expression of tristetraprolin in human cancer cells promotes biogenesis of let-7 by down-regulation of Lin28. Nucleic Acids Res. 2012;40:3856-69 pubmed 出版商

PAGAN B, Isidro A, Cruz M, Ren Y, Coppola D, Wu J, et al. Erlotinib inhibits progression to dysplasia in a colitis-associated colon cancer model. World J Gastroenterol. 2011;17:4858-66 pubmed 出版商

Ji H, Wu G, Zhan X, Nolan A, Koh C, De Marzo A, et al. Cell-type independent MYC target genes reveal a primordial signature involved in biomass accumulation. PLoS ONE. 2011;6:e26057 pubmed 出版商

Scholer Dahirel A, Schlabach M, Loo A, Bagdasarian L, MEYER R, Guo R, et al. Maintenance of adenomatous polyposis coli (APC)-mutant colorectal cancer is dependent on Wnt/beta-catenin signaling. Proc Natl Acad Sci U S A. 2011;108:17135-40 pubmed 出版商

Zhang X, Farrell A, Daniel C, Arnold H, Scanlan C, Laraway B, et al. Mechanistic insight into Myc stabilization in breast cancer involving aberrant Axin1 expression. Proc Natl Acad Sci U S A. 2012;109:2790-5 pubmed 出版商

Bruning U, Cerone L, Neufeld Z, Fitzpatrick S, Cheong A, Scholz C, et al. MicroRNA-155 promotes resolution of hypoxia-inducible factor 1alpha activity during prolonged hypoxia. Mol Cell Biol. 2011;31:4087-96 pubmed 出版商

Karst A, Levanon K, Drapkin R. Modeling high-grade serous ovarian carcinogenesis from the fallopian tube. Proc Natl Acad Sci U S A. 2011;108:7547-52 pubmed 出版商

Nguyen A, Albers C, Holcombe R. Differentiation of tubular and villous adenomas based on Wnt pathway-related gene expression profiles. Int J Mol Med. 2010;26:121-5 pubmed

Escamilla Powers J, Daniel C, Farrell A, Taylor K, Zhang X, Byers S, et al. The tumor suppressor protein HBP1 is a novel c-myc-binding protein that negatively regulates c-myc transcriptional activity. J Biol Chem. 2010;285:4847-58 pubmed 出版商

Rohan J, Weigel N. 1Alpha,25-dihydroxyvitamin D3 reduces c-Myc expression, inhibiting proliferation and causing G1 accumulation in C4-2 prostate cancer cells. Endocrinology. 2009;150:2046-54 pubmed 出版商