产品简要
公司名称 :
艾博抗(上海)贸易有限公司
其他品牌 :
Epitomics, Ascent Scientific, MitoSciences
产品类型 :
抗体
产品名称 :
Anti-Paxillin antibody [Y113]
目录 :
ab32084
规格 :
10微升, 100微升
克隆性 :
单克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
克隆名称 :
Y113
反应物种 :
人类, 小鼠, 大鼠, ,
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀, 流式细胞仪, 免疫组化-石蜡切片, 其他
文章摘录数: 50
出版应用/物种/样本/稀释参考文献
  • 免疫细胞化学; 小鼠; 1:250; 图 s2a
Kim J, Hwang K, Dang B, Eom M, Kong I, Gwack Y, et al. Insulin-activated store-operated Ca2+ entry via Orai1 induces podocyte actin remodeling and causes proteinuria. Nat Commun. 2021;12:6537 pubmed 出版商
  • 免疫印迹; 人类; 图 2g
Zhang L, Yao L, Zhou W, Tian J, Ruan B, Lu Z, et al. miR-497 defect contributes to gastric cancer tumorigenesis and progression via regulating CDC42/ITGB1/FAK/PXN/AKT signaling. Mol Ther Nucleic Acids. 2021;25:567-577 pubmed 出版商
  • 免疫细胞化学; 人类; 图 2s1b
Shi K, Yin X, Cai M, Yan Y, Jia C, Ma P, et al. PAX8 regulon in human ovarian cancer links lineage dependency with epigenetic vulnerability to HDAC inhibitors. elife. 2019;8: pubmed 出版商
  • 免疫印迹; 人类; 1:3000; 图 6c
Frank A, Ebersberger S, Fink A, Lampe S, Weigert A, Schmid T, et al. Apoptotic tumor cell-derived microRNA-375 uses CD36 to alter the tumor-associated macrophage phenotype. Nat Commun. 2019;10:1135 pubmed 出版商
  • 免疫细胞化学; 人类; 1:800; 图 3a
Moro A, Driscoll T, Boraas L, Armero W, Kasper D, Baeyens N, et al. MicroRNA-dependent regulation of biomechanical genes establishes tissue stiffness homeostasis. Nat Cell Biol. 2019;21:348-358 pubmed 出版商
  • 免疫细胞化学; 人类; 图 1f
Gao Q, Yang Z, Xu S, Li X, Yang X, Jin P, et al. Heterotypic CAF-tumor spheroids promote early peritoneal metastatis of ovarian cancer. J Exp Med. 2019;216:688-703 pubmed 出版商
  • 其他; 人类; 图 4c
Ng P, Li J, Jeong K, Shao S, Chen H, Tsang Y, et al. Systematic Functional Annotation of Somatic Mutations in Cancer. Cancer Cell. 2018;33:450-462.e10 pubmed 出版商
  • 免疫组化; 小鼠; 1:200; 图 s1a
Rashid M, Belmont J, Carpenter D, Turner C, Olson E. Neural-specific deletion of the focal adhesion adaptor protein paxillin slows migration speed and delays cortical layer formation. Development. 2017;144:4002-4014 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 3i, 6c
Amin E, Liu Y, Deng S, Tan K, Chudgar N, Mayo M, et al. The RNA-editing enzyme ADAR promotes lung adenocarcinoma migration and invasion by stabilizing FAK. Sci Signal. 2017;10: pubmed 出版商
  • 免疫细胞化学; 人类; 1:200; 图 7A
Wei X, Wang X, Zhan J, Chen Y, Fang W, Zhang L, et al. Smurf1 inhibits integrin activation by controlling Kindlin-2 ubiquitination and degradation. J Cell Biol. 2017;216:1455-1471 pubmed 出版商
  • 免疫组化; 人类; 图 8d
  • 免疫印迹; 人类; 图 s8a
Mekhdjian A, Kai F, Rubashkin M, Prahl L, Przybyla L, McGregor A, et al. Integrin-mediated traction force enhances paxillin molecular associations and adhesion dynamics that increase the invasiveness of tumor cells into a three-dimensional extracellular matrix. Mol Biol Cell. 2017;28:1467-1488 pubmed 出版商
  • 免疫细胞化学; 小鼠; 图 3e
  • 免疫印迹; 小鼠; 1:300; 图 3a
Shen X, Jia Z, D Alonzo D, Wang X, Bruder E, Emch F, et al. HECTD1 controls the protein level of IQGAP1 to regulate the dynamics of adhesive structures. Cell Commun Signal. 2017;15:2 pubmed 出版商
  • 免疫印迹; 人类; 图 3c
Tsai C, Lin Y, Huang C, Shih C, Tsai Y, Tsao N, et al. Thrombomodulin regulates monocye differentiation via PKC? and ERK1/2 pathway in vitro and in atherosclerotic artery. Sci Rep. 2016;6:38421 pubmed 出版商
  • 免疫细胞化学; 人类; 图 s6b
  • 免疫印迹; 人类; 图 s7b
Ross Adams H, Ball S, Lawrenson K, Halim S, Russell R, Wells C, et al. HNF1B variants associate with promoter methylation and regulate gene networks activated in prostate and ovarian cancer. Oncotarget. 2016;7:74734-74746 pubmed 出版商
  • 免疫印迹; 人类; 1:200; 图 st1
Treindl F, Ruprecht B, Beiter Y, Schultz S, Döttinger A, Staebler A, et al. A bead-based western for high-throughput cellular signal transduction analyses. Nat Commun. 2016;7:12852 pubmed 出版商
  • 免疫细胞化学; 人类; 1:100; 图 6d
Harrington K, Clevenger C. Identification of NEK3 Kinase Threonine 165 as a Novel Regulatory Phosphorylation Site That Modulates Focal Adhesion Remodeling Necessary for Breast Cancer Cell Migration. J Biol Chem. 2016;291:21388-21406 pubmed
  • 免疫细胞化学; 人类; 图 3a
Hiroyasu S, Colburn Z, Jones J. A hemidesmosomal protein regulates actin dynamics and traction forces in motile keratinocytes. FASEB J. 2016;30:2298-310 pubmed 出版商
  • 免疫细胞化学; 人类; 1:200; 图 3
Chen N, Uddin B, Voit R, Schiebel E. Human phosphatase CDC14A is recruited to the cell leading edge to regulate cell migration and adhesion. Proc Natl Acad Sci U S A. 2016;113:990-5 pubmed 出版商
  • 免疫细胞化学; 小鼠; 图 5
  • 免疫细胞化学; 人类; 1:2000; 图 1b, 5
  • 免疫印迹; 人类; 1:5000; 图 1d
Fuhrmann A, Engler A. The cytoskeleton regulates cell attachment strength. Biophys J. 2015;109:57-65 pubmed 出版商
  • 免疫细胞化学; 小鼠; 1:2000
  • 免疫细胞化学; 人类; 1:2000
Fuhrmann A, Li J, Chien S, Engler A. Cation type specific cell remodeling regulates attachment strength. PLoS ONE. 2014;9:e102424 pubmed 出版商
  • 免疫细胞化学; 人类
Holle A, Tang X, Vijayraghavan D, Vincent L, Fuhrmann A, Choi Y, et al. In situ mechanotransduction via vinculin regulates stem cell differentiation. Stem Cells. 2013;31:2467-77 pubmed 出版商
Garbett D, Bisaria A, Yang C, McCarthy D, Hayer A, Moerner W, et al. T-Plastin reinforces membrane protrusions to bridge matrix gaps during cell migration. Nat Commun. 2020;11:4818 pubmed 出版商
Pedrosa A, Murphy K, Nogueira A, Brinkworth A, Thwaites T, Aaron J, et al. A post-invasion role for Chlamydia type III effector TarP in modulating the dynamics and organization of host cell focal adhesions. J Biol Chem. 2020;295:14763-14779 pubmed 出版商
Lambert J, Makin K, Akbareian S, Johnson R, Alghamdi A, Robinson S, et al. ADAMTS-1 and syndecan-4 intersect in the regulation of cell migration and angiogenesis. J Cell Sci. 2020;133: pubmed 出版商
Panciera T, Citron A, Di Biagio D, Battilana G, Gandin A, Giulitti S, et al. Reprogramming normal cells into tumour precursors requires ECM stiffness and oncogene-mediated changes of cell mechanical properties. Nat Mater. 2020;19:797-806 pubmed 出版商
Heuzé M, Sankara Narayana G, D Alessandro J, Cellerin V, Dang T, Williams D, et al. Myosin II isoforms play distinct roles in adherens junction biogenesis. elife. 2019;8: pubmed 出版商
Sengupta S, Rothenberg K, Li H, Hoffman B, Bursac N. Altering integrin engagement regulates membrane localization of Kir2.1 channels. J Cell Sci. 2019;132: pubmed 出版商
Fourrière L, Kasri A, Gareil N, Bardin S, Bousquet H, Pereira D, et al. RAB6 and microtubules restrict protein secretion to focal adhesions. J Cell Biol. 2019;: pubmed 出版商
Tsygankova O, Keen J. A unique role for clathrin light chain A in cell spreading and migration. J Cell Sci. 2019;132: pubmed 出版商
Colburn Z, Jones J. Complexes of α6β4 integrin and vimentin act as signaling hubs to regulate epithelial cell migration. J Cell Sci. 2018;131: pubmed 出版商
Dix C, Matthews H, Uroz M, McLaren S, Wolf L, Heatley N, et al. The Role of Mitotic Cell-Substrate Adhesion Re-modeling in Animal Cell Division. Dev Cell. 2018;45:132-145.e3 pubmed 出版商
Chizhik A, Wollnik C, Ruhlandt D, Karedla N, Chizhik A, Hauke L, et al. Dual-color metal-induced and förster resonance energy transfer for cell nanoscopy. Mol Biol Cell. 2018;: pubmed 出版商
McCarthy C, Wenceslau C, Ogbi S, Szasz T, Webb R. Toll-Like Receptor 9-Dependent AMPKα Activation Occurs via TAK1 and Contributes to RhoA/ROCK Signaling and Actin Polymerization in Vascular Smooth Muscle Cells. J Pharmacol Exp Ther. 2018;365:60-71 pubmed 出版商
Cook J, Ueno N, Lodoen M. Toxoplasma gondii disrupts β1 integrin signaling and focal adhesion formation during monocyte hypermotility. J Biol Chem. 2018;293:3374-3385 pubmed 出版商
Gan Z, Ding L, Burckhardt C, Lowery J, Zaritsky A, Sitterley K, et al. Vimentin Intermediate Filaments Template Microtubule Networks to Enhance Persistence in Cell Polarity and Directed Migration. Cell Syst. 2016;3:252-263.e8 pubmed 出版商
Courtheoux T, Enchev R, Lampert F, Gerez J, Beck J, Picotti P, et al. Cortical dynamics during cell motility are regulated by CRL3(KLHL21) E3 ubiquitin ligase. Nat Commun. 2016;7:12810 pubmed 出版商
García E, Ragazzini C, Yu X, Cuesta García E, Bernardino de la Serna J, Zech T, et al. WIP and WICH/WIRE co-ordinately control invadopodium formation and maturation in human breast cancer cell invasion. Sci Rep. 2016;6:23590 pubmed 出版商
Ellison T, Atkinson S, Steri V, Kirkup B, Preedy M, Johnson R, et al. Suppression of β3-integrin in mice triggers a neuropilin-1-dependent change in focal adhesion remodelling that can be targeted to block pathological angiogenesis. Dis Model Mech. 2015;8:1105-19 pubmed 出版商
Chen D, Wang Z, Ren C, Zeng Z, Wang D, Luo H, et al. Abnormal expression of paxillin correlates with tumor progression and poor survival in patients with gastric cancer. J Transl Med. 2013;11:277 pubmed 出版商
van Leeuwen I, Higgins M, Campbell J, McCarthy A, Sachweh M, Navarro A, et al. Modulation of p53 C-terminal acetylation by mdm2, p14ARF, and cytoplasmic SirT2. Mol Cancer Ther. 2013;12:471-80 pubmed 出版商
Veith C, Marsh L, Wygrecka M, Rutschmann K, Seeger W, Weissmann N, et al. Paxillin regulates pulmonary arterial smooth muscle cell function in pulmonary hypertension. Am J Pathol. 2012;181:1621-33 pubmed 出版商
Pescatore L, Bonatto D, Forti F, Sadok A, Kovacic H, Laurindo F. Protein disulfide isomerase is required for platelet-derived growth factor-induced vascular smooth muscle cell migration, Nox1 NADPH oxidase expression, and RhoGTPase activation. J Biol Chem. 2012;287:29290-300 pubmed 出版商
Tomkiewicz C, Herry L, Bui L, Metayer C, Bourdeloux M, Barouki R, et al. The aryl hydrocarbon receptor regulates focal adhesion sites through a non-genomic FAK/Src pathway. Oncogene. 2013;32:1811-20 pubmed 出版商
Patel A, Dash P. Formation of atypical podosomes in extravillous trophoblasts regulates extracellular matrix degradation. Eur J Cell Biol. 2012;91:171-9 pubmed 出版商
Lawson C, Lim S, Uryu S, Chen X, Calderwood D, Schlaepfer D. FAK promotes recruitment of talin to nascent adhesions to control cell motility. J Cell Biol. 2012;196:223-32 pubmed 出版商
Zhu H, Riau A, Beuerman R. Epithelial microfilament regulators show regional distribution in mouse conjunctiva. Mol Vis. 2010;16:2215-24 pubmed
To W, Midwood K. Cryptic domains of tenascin-C differentially control fibronectin fibrillogenesis. Matrix Biol. 2010;29:573-85 pubmed 出版商
Curtis M, Sharma S, Desai T, Russell B. Hypertrophy, gene expression, and beating of neonatal cardiac myocytes are affected by microdomain heterogeneity in 3D. Biomed Microdevices. 2010;12:1073-85 pubmed 出版商
Chen T, Luque A, Lee S, Anderson S, Segura T, Iruela Arispe M. Anchorage of VEGF to the extracellular matrix conveys differential signaling responses to endothelial cells. J Cell Biol. 2010;188:595-609 pubmed 出版商
Goldyn A, Rioja B, Spatz J, Ballestrem C, Kemkemer R. Force-induced cell polarisation is linked to RhoA-driven microtubule-independent focal-adhesion sliding. J Cell Sci. 2009;122:3644-51 pubmed 出版商
产品信息
目录号 :
ab32084
ItemName :
Anti-Paxillin antibody [Y113]
类别 :
抗体
宿主 :
克隆性 :
单克隆
共轭标签 :
未共轭
克隆名称 :
Y113
规格 :
10微升, 100微升
物种摘要 :
Cow, Dog, Hu, Ms, Rat
应用摘要 :
Flow Cyt, ICC/IF, IHC-P, IP, WB
公司信息
艾博抗(上海)贸易有限公司
上海市浦东新区伽利略路338号5幢4层5401室
cn.technical@abcam.com
http://www.abcam.cn
400-628-6880 86-21-5110 5938
公司总部: 英国
Abcam是全球知名的生命科学研究领域产品提供商,产品涵盖一抗、二抗、蛋白、多肽及ELISA kit。