产品简要
公司名称 :
艾博抗(上海)贸易有限公司
其他品牌 :
Epitomics, Ascent Scientific, MitoSciences
产品类型 :
抗体
产品名称 :
抗IKB甲抗体[E130]
目录 :
ab32518
规格 :
10微升, 100微升
克隆性 :
单克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
克隆名称 :
E130
反应物种 :
人类, 小鼠, 大鼠, pigs
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀, 流式细胞仪, 免疫组化-石蜡切片, proximity ligation assay
文章摘录数: 66
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 人类; 图 s4d
Du Y, Zhang M, Liu X, Li Z, Hu M, Tian Y, et al. CDC20 promotes bone formation via APC/C dependent ubiquitination and degradation of p65. EMBO Rep. 2021;22:e52576 pubmed 出版商
  • 免疫印迹; 人类; 1:3000; 图 2e, 2f
Masaki T, Kodera Y, Terasaki M, Fujimoto K, Hirano T, Shichiri M. GIP_HUMAN[22-51] is a new proatherogenic peptide identified by native plasma peptidomics. Sci Rep. 2021;11:14470 pubmed 出版商
  • 免疫印迹; 小鼠; 图 6a
Fan H, Wang S, Wang H, Sun M, Wu S, Bao W. Melatonin Ameliorates the Toxicity Induced by Deoxynivalenol in Murine Ovary Granulosa Cells by Antioxidative and Anti-Inflammatory Effects. Antioxidants (Basel). 2021;10: pubmed 出版商
  • 免疫印迹; 大鼠; 图 6a
Jiang T, Xu S, Shen Y, Xu Y, Li Y. Genistein Attenuates Isoflurane-Induced Neuroinflammation by Inhibiting TLR4-Mediated Microglial-Polarization in vivo and in vitro. J Inflamm Res. 2021;14:2587-2600 pubmed 出版商
  • 免疫印迹; 人类; 图 2a
  • 免疫印迹; 小鼠; 1:1000; 图 1e
Zhang Z, Zhang L, Zhang Q, Liu B, Li F, Xin Y, et al. HO-1/CO Maintains Intestinal Barrier Integrity through NF-κB/MLCK Pathway in Intestinal HO-1-/- Mice. Oxid Med Cell Longev. 2021;2021:6620873 pubmed 出版商
  • 免疫组化-石蜡切片; 大鼠; 1:100; 图 6c
Xu H, Wang Y, Luo Y. OTULIN is a new target of EA treatment in the alleviation of brain injury and glial cell activation via suppression of the NF-κB signalling pathway in acute ischaemic stroke rats. Mol Med. 2021;27:37 pubmed 出版商
  • 免疫印迹; 小鼠; 1:500; 图 5a
Yang Y, Deng R, Chen Z, Yao L, Yang X, Xiang D. Piperazine ferulate attenuates high glucose‑induced mesangial cell injury via the regulation of p66Shc. Mol Med Rep. 2021;23: pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 4a
An J, Kerns K, Ouellette A, Robinson L, Morris H, Kaczorowski C, et al. Rapamycin rejuvenates oral health in aging mice. elife. 2020;9: pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 3d
Xu M, Ge C, Qin Y, Lou D, Li Q, Feng J, et al. Functional loss of inactive rhomboid-like protein 2 mitigates obesity by suppressing pro-inflammatory macrophage activation-triggered adipose inflammation. Mol Metab. 2020;34:112-123 pubmed 出版商
  • 免疫印迹; 人类; 图 2c
Jia Z, Huang Y, Ji X, Sun J, Fu G. Ticagrelor and clopidogrel suppress NF-κB signaling pathway to alleviate LPS-induced dysfunction in vein endothelial cells. BMC Cardiovasc Disord. 2019;19:318 pubmed 出版商
  • 免疫印迹; 大鼠; 1:1000; 图 5a
Zhang G, Liu Y, Xu L, Sha C, Zhang H, Xu W. Resveratrol alleviates lipopolysaccharide-induced inflammation in PC-12 cells and in rat model. BMC Biotechnol. 2019;19:10 pubmed 出版商
  • 免疫印迹; 人类; 图 s10a
Hu Y, Guo F, Xu Y, Li P, Lu Z, McVey D, et al. Long noncoding RNA NEXN-AS1 mitigates atherosclerosis by regulating the actin-binding protein NEXN. J Clin Invest. 2019;129:1115-1128 pubmed 出版商
  • 免疫印迹; 大鼠; 1:1000; 图 4a
Wu J, Liu Y, Liang J, Huang Q, Dou Y, Nie J, et al. Protective role of ?-patchoulene from Pogostemon cablin against indomethacin-induced gastric ulcer in rats: Involvement of anti-inflammation and angiogenesis. Phytomedicine. 2018;39:111-118 pubmed 出版商
  • 免疫印迹; 小鼠; 图 5d
Chen L, Hayden M, Gilmore E, Alexander Savino C, Oleksyn D, Gillespie K, et al. PKK deletion in basal keratinocytes promotes tumorigenesis after chemical carcinogenesis. Carcinogenesis. 2018;39:418-428 pubmed 出版商
  • 免疫印迹; 大鼠; 图 6h
Shi Y, Zhang X, Chen C, Tang M, Wang Z, Liang X, et al. Schisantherin A attenuates ischemia/reperfusion-induced neuronal injury in rats via regulation of TLR4 and C5aR1 signaling pathways. Brain Behav Immun. 2017;66:244-256 pubmed 出版商
  • 免疫印迹; 小鼠; 图 s3c
Vander Lugt B, Riddell J, Khan A, Hackney J, Lesch J, DeVoss J, et al. Transcriptional determinants of tolerogenic and immunogenic states during dendritic cell maturation. J Cell Biol. 2017;216:779-792 pubmed 出版商
  • 免疫印迹; 小鼠; 1:2500; 图 6b
Meng Z, Zhao T, Zhou K, Zhong Q, Wang Y, Xiong X, et al. A20 Ameliorates Intracerebral Hemorrhage-Induced Inflammatory Injury by Regulating TRAF6 Polyubiquitination. J Immunol. 2017;198:820-831 pubmed 出版商
  • proximity ligation assay; 人类; 图 4a
  • 免疫印迹; 人类
Turner J, Kashyap T, Dawson J, Gomez J, Bauer A, Grant S, et al. XPO1 inhibitor combination therapy with bortezomib or carfilzomib induces nuclear localization of IκBα and overcomes acquired proteasome inhibitor resistance in human multiple myeloma. Oncotarget. 2016;7:78896-78909 pubmed 出版商
  • 免疫印迹; pigs ; 1:5000; 图 1d
Yang G, Zhu Y, Zhang W, Zhou D, Zhai C, Wang J. Influence of orally fed a select mixture of Bacillus probiotics on intestinal T-cell migration in weaned MUC4 resistant pigs following Escherichia coli challenge. Vet Res. 2016;47:71 pubmed 出版商
  • 免疫印迹; 小鼠; 图 5
Ni T, Liu Y, Peng Y, Li M, Fang Y, Yao M. Substance P induces inflammatory responses involving NF-?B in genetically diabetic mice skin fibroblasts co-cultured with macrophages. Am J Transl Res. 2016;8:2179-88 pubmed
  • 免疫印迹; 人类; 1:1000; 图 4f
Zhang Y, Shen L, Stupack D, Bai N, Xun J, Ren G, et al. JMJD3 promotes survival of diffuse large B-cell lymphoma subtypes via distinct mechanisms. Oncotarget. 2016;7:29387-99 pubmed 出版商
  • 免疫印迹; pigs ; 图 3d
Sun M, Zhu S, Li Y, Lin J, Gong S, Jiao G, et al. An essential role for the intra-oocyte MAPK activity in the NSN-to-SN transition of germinal vesicle chromatin configuration in porcine oocytes. Sci Rep. 2016;6:23555 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 图 3a
  • 免疫印迹; 小鼠; 图 6e
Roy A, Rangasamy S, Kundu M, Pahan K. BPOZ-2 Gene Delivery Ameliorates Alpha-Synucleinopathy in A53T Transgenic Mouse Model of Parkinson's Disease. Sci Rep. 2016;6:22067 pubmed 出版商
  • 免疫组化; 人类; 图 8a
Gravina G, Mancini A, Sanità P, Vitale F, Marampon F, Ventura L, et al. KPT-330, a potent and selective exportin-1 (XPO-1) inhibitor, shows antitumor effects modulating the expression of cyclin D1 and survivin [corrected] in prostate cancer models. BMC Cancer. 2015;15:941 pubmed 出版商
  • 免疫印迹; 人类
Picot N, Guerrette R, Beauregard A, Jean S, Michaud P, Harquail J, et al. Mammaglobin 1 promotes breast cancer malignancy and confers sensitivity to anticancer drugs. Mol Carcinog. 2016;55:1150-62 pubmed 出版商
  • 免疫印迹; 人类; 1:1000
Nakayama T, Al Maawali A, El Quessny M, Rajab A, Khalil S, Stoler J, et al. Mutations in PYCR2, Encoding Pyrroline-5-Carboxylate Reductase 2, Cause Microcephaly and Hypomyelination. Am J Hum Genet. 2015;96:709-19 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1500; 图 5a
Tang Y, Jiang J, Wang S, Liu Z, Tang X, Peng J, et al. TLR4/NF-κB signaling contributes to chronic unpredictable mild stress-induced atherosclerosis in ApoE-/- mice. PLoS ONE. 2015;10:e0123685 pubmed 出版商
  • 免疫印迹; 人类
Cumming K, Raastad T, Holden G, Bastani N, Schneeberger D, Paronetto M, et al. Effects of vitamin C and E supplementation on endogenous antioxidant systems and heat shock proteins in response to endurance training. Physiol Rep. 2014;2: pubmed 出版商
  • 免疫印迹; 小鼠; 1:2500; 图 3
Dvoriantchikova G, Ivanov D. Tumor necrosis factor-alpha mediates activation of NF-κB and JNK signaling cascades in retinal ganglion cells and astrocytes in opposite ways. Eur J Neurosci. 2014;40:3171-8 pubmed 出版商
  • 免疫印迹; 人类; 图 4a
Benzina S, Harquail J, Jean S, Beauregard A, Colquhoun C, Carroll M, et al. Deoxypodophyllotoxin isolated from Juniperus communis induces apoptosis in breast cancer cells. Anticancer Agents Med Chem. 2015;15:79-88 pubmed
Xiao C, Zhang W, Hua M, Chen H, Yang B, Wang Y, et al. TRIM27 interacts with Iκbα to promote the growth of human renal cancer cells through regulating the NF-κB pathway. BMC Cancer. 2021;21:841 pubmed 出版商
Li Y, Wang J, Ma Y, Du W, Feng H, Feng K, et al. MicroRNA-15b shuttled by bone marrow mesenchymal stem cell-derived extracellular vesicles binds to WWP1 and promotes osteogenic differentiation. Arthritis Res Ther. 2020;22:269 pubmed 出版商
Xiao L, Zhong M, Huang Y, Zhu J, Tang W, Li D, et al. Puerarin alleviates osteoporosis in the ovariectomy-induced mice by suppressing osteoclastogenesis via inhibition of TRAF6/ROS-dependent MAPK/NF-κB signaling pathways. Aging (Albany NY). 2020;12:21706-21729 pubmed 出版商
Sirong S, Yang C, Taoran T, Songhang L, Shiyu L, Yuxin Z, et al. Effects of tetrahedral framework nucleic acid/wogonin complexes on osteoarthritis. Bone Res. 2020;8:6 pubmed 出版商
Bai Y, Li Z, Liu W, Gao D, Liu M, Zhang P. Biochanin A attenuates myocardial ischemia/reperfusion injury through the TLR4/NF-κB/NLRP3 signaling pathway. Acta Cir Bras. 2019;34:e201901104 pubmed 出版商
Gu R, Huang Z, Liu H, Qing Q, Zhuan Z, Yang L, et al. Moracin attenuates LPS-induced inflammation in nucleus pulposus cells via Nrf2/HO-1 and NF-κB/TGF-β pathway. Biosci Rep. 2019;39: pubmed 出版商
Lin Y, Huang S, Wu J, Chu T, Huang S, Lee C, et al. Novel HDGF/HIF-1α/VEGF axis in oral cancer impacts disease prognosis. BMC Cancer. 2019;19:1083 pubmed 出版商
Mayr Buro C, Schlereth E, Beuerlein K, Tenekeci U, Meier Soelch J, Schmitz M, et al. Single-Cell Analysis of Multiple Steps of Dynamic NF-κB Regulation in Interleukin-1α-Triggered Tumor Cells Using Proximity Ligation Assays. Cancers (Basel). 2019;11: pubmed 出版商
Sui H, Lou A, Li Z, Yang J. Lidocaine inhibits growth, migration and invasion of gastric carcinoma cells by up-regulation of miR-145. BMC Cancer. 2019;19:233 pubmed 出版商
Arora H, Wilcox S, Johnson L, Munro L, Eyford B, Pfeifer C, et al. The ATP-Binding Cassette Gene ABCF1 Functions as an E2 Ubiquitin-Conjugating Enzyme Controlling Macrophage Polarization to Dampen Lethal Septic Shock. Immunity. 2019;50:418-431.e6 pubmed 出版商
Huang D, Bi C, Zhao Q, Ding X, Bian C, Wang H, et al. Knockdown long non-coding RNA ANRIL inhibits proliferation, migration and invasion of HepG2 cells by down-regulation of miR-191. BMC Cancer. 2018;18:919 pubmed 出版商
Liu G, Zhang W. Long non-coding RNA HOTAIR promotes UVB-induced apoptosis and inflammatory injury by up-regulation of PKR in keratinocytes. Braz J Med Biol Res. 2018;51:e6896 pubmed 出版商
Ren K, Yong C, Yuan H, Cao B, Zhao K, Wang J. TNF-? inhibits SCF, ghrelin, and substance P expressions through the NF-?B pathway activation in interstitial cells of Cajal. Braz J Med Biol Res. 2018;51:e7065 pubmed 出版商
Yao D, Xu L, Xu O, Li R, Chen M, Shen H, et al. O-Linked ?-N-Acetylglucosamine Modification of A20 Enhances the Inhibition of NF-?B (Nuclear Factor-?B) Activation and Elicits Vascular Protection After Acute Endoluminal Arterial Injury. Arterioscler Thromb Vasc Biol. 2018;38:1309-1320 pubmed 出版商
Hernandes M, LASSEGUE B, Hilenski L, Adams J, Gao N, Kuan C, et al. Polymerase delta-interacting protein 2 deficiency protects against blood-brain barrier permeability in the ischemic brain. J Neuroinflammation. 2018;15:45 pubmed 出版商
Yang G, Li S, Li B, Cheng L, Jiang P, Tian Z, et al. Protective Effects of Garlic-Derived S-Allylmercaptocysteine on IL-1β-Stimulated Chondrocytes by Regulation of MMPs/TIMP-1 Ratio and Type II Collagen Expression via Suppression of NF-κB Pathway. Biomed Res Int. 2017;2017:8686207 pubmed 出版商
Liu Y, Wang D, Yang Y, Lei W. Effects and mechanism of dexmedetomidine on neuronal cell injury induced by hypoxia-ischemia. BMC Anesthesiol. 2017;17:117 pubmed 出版商
Zhang Z, Fan H, Yang M, Zhang Z, Liu K. Therapeutic effect of a hydroxynaphthoquinone fraction on dextran sulfate sodium-induced ulcerative colitis. World J Gastroenterol. 2014;20:15310-8 pubmed 出版商
Skalniak L, Dziendziel M, Jura J. MCPIP1 contributes to the toxicity of proteasome inhibitor MG-132 in HeLa cells by the inhibition of NF-?B. Mol Cell Biochem. 2014;395:253-63 pubmed 出版商
Wann A, Chapple J, Knight M. The primary cilium influences interleukin-1?-induced NF?B signalling by regulating IKK activity. Cell Signal. 2014;26:1735-42 pubmed 出版商
Kim S, Kim H, Lee J, Park K, Jeon G, Shon J, et al. Intermittent hypoxia can aggravate motor neuronal loss and cognitive dysfunction in ALS mice. PLoS ONE. 2013;8:e81808 pubmed 出版商
Mudaliar M, Haggart R, Miele G, Sellar G, Tan K, Goodlad J, et al. Comparative gene expression profiling identifies common molecular signatures of NF-?B activation in canine and human diffuse large B cell lymphoma (DLBCL). PLoS ONE. 2013;8:e72591 pubmed 出版商
Skalniak L, Koj A, Jura J. Proteasome inhibitor MG-132 induces MCPIP1 expression. FEBS J. 2013;280:2665-74 pubmed 出版商
Almeida M, Azevedo M, Xekouki P, Bimpaki E, Horvath A, Collins M, et al. Activation of cyclic AMP signaling leads to different pathway alterations in lesions of the adrenal cortex caused by germline PRKAR1A defects versus those due to somatic GNAS mutations. J Clin Endocrinol Metab. 2012;97:E687-93 pubmed 出版商
Akinsete J, Ion G, Witte T, Hardman W. Consumption of high ?-3 fatty acid diet suppressed prostate tumorigenesis in C3(1) Tag mice. Carcinogenesis. 2012;33:140-8 pubmed 出版商
Portugal Cohen M, Soroka Y, Frusić Zlotkin M, Verkhovsky L, Brégégère F, Neuman R, et al. Skin organ culture as a model to study oxidative stress, inflammation and structural alterations associated with UVB-induced photodamage. Exp Dermatol. 2011;20:749-55 pubmed 出版商
Stewart M, Roy P. Role of cellular caspases, nuclear factor-kappa B and interferon regulatory factors in Bluetongue virus infection and cell fate. Virol J. 2010;7:362 pubmed 出版商
Li Z, Tang Q, Wang J, Zhou L, Huang W, Liu R, et al. Hepatitis C virus core protein induces malignant transformation of biliary epithelial cells by activating nuclear factor-kappaB pathway. J Gastroenterol Hepatol. 2010;25:1315-20 pubmed 出版商
King A, Collins F, Klonisch T, Sallenave J, Critchley H, Saunders P. An additive interaction between the NFkappaB and estrogen receptor signalling pathways in human endometrial epithelial cells. Hum Reprod. 2010;25:510-8 pubmed 出版商
Zhou Y, Mohsenin A, Morschl E, Young H, Molina J, Ma W, et al. Enhanced airway inflammation and remodeling in adenosine deaminase-deficient mice lacking the A2B adenosine receptor. J Immunol. 2009;182:8037-46 pubmed 出版商
Ramadas R, Wu L, LeVine A. Surfactant protein A enhances production of secretory leukoprotease inhibitor and protects it from cleavage by matrix metalloproteinases. J Immunol. 2009;182:1560-7 pubmed
Bournazou I, Pound J, Duffin R, Bournazos S, Melville L, Brown S, et al. Apoptotic human cells inhibit migration of granulocytes via release of lactoferrin. J Clin Invest. 2009;119:20-32 pubmed 出版商
Palazzo M, Gariboldi S, Zanobbio L, Selleri S, Dusio G, Mauro V, et al. Sodium-dependent glucose transporter-1 as a novel immunological player in the intestinal mucosa. J Immunol. 2008;181:3126-36 pubmed
Turnbull C, Marcarino P, Sheldrake T, Lazzarato L, Cena C, Fruttero R, et al. A novel hybrid aspirin-NO-releasing compound inhibits TNFalpha release from LPS-activated human monocytes and macrophages. J Inflamm (Lond). 2008;5:12 pubmed 出版商
Gariboldi S, Palazzo M, Zanobbio L, Selleri S, Sommariva M, Sfondrini L, et al. Low molecular weight hyaluronic acid increases the self-defense of skin epithelium by induction of beta-defensin 2 via TLR2 and TLR4. J Immunol. 2008;181:2103-10 pubmed
Bournazos S, Rennie J, Hart S, Fox K, Dransfield I. Monocyte functional responsiveness after PSGL-1-mediated platelet adhesion is dependent on platelet activation status. Arterioscler Thromb Vasc Biol. 2008;28:1491-8 pubmed 出版商
产品信息
目录号 :
ab32518
ItemName :
抗IKB甲抗体[E130]
类别 :
抗体
宿主 :
克隆性 :
单克隆
共轭标签 :
未共轭
克隆名称 :
E130
规格 :
10微升, 100微升
物种摘要 :
Hm, Hu, Ms, Rat
应用摘要 :
Flow Cyt, ICC/IF, IHC-P, IP, WB
公司信息
艾博抗(上海)贸易有限公司
上海市浦东新区伽利略路338号5幢4层5401室
cn.technical@abcam.com
http://www.abcam.cn
400-628-6880 86-21-5110 5938
公司总部: 英国
Abcam是全球知名的生命科学研究领域产品提供商,产品涵盖一抗、二抗、蛋白、多肽及ELISA kit。