产品简要
公司名称 :
艾博抗(上海)贸易有限公司
其他品牌 :
Epitomics, Ascent Scientific, MitoSciences
产品类型 :
抗体
产品名称 :
抗BCRP/ATP结合转运蛋白G超家族成员2抗体[BXP-21]
目录 :
ab3380
规格 :
250微升
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
BXP-21
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 免疫细胞化学, 流式细胞仪, 免疫组化-石蜡切片, 免疫组化-冰冻切片
文章摘录数: 41
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 人类; 1:1000; 图 3a
Kitajima Y, Ishii T, Kohda T, Ishizuka M, Yamazaki K, Nishimura Y, et al. Mechanistic study of PpIX accumulation using the JFCR39 cell panel revealed a role for dynamin 2-mediated exocytosis. Sci Rep. 2019;9:8666 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:150; 图 s4
Weidner L, Kannan P, Mitsios N, Kang S, Hall M, Theodore W, et al. The expression of inflammatory markers and their potential influence on efflux transporters in drug-resistant mesial temporal lobe epilepsy tissue. Epilepsia. 2018;59:1507-1517 pubmed 出版商
  • 免疫印迹; 人类; 图 9c
  • 免疫印迹; 小鼠; 图 9c
Sekhar G, Georgian A, Sanderson L, Vizcay Barrena G, Brown R, Muresan P, et al. Organic cation transporter 1 (OCT1) is involved in pentamidine transport at the human and mouse blood-brain barrier (BBB). PLoS ONE. 2017;12:e0173474 pubmed 出版商
  • 流式细胞仪; 人类; 1:200; 图 2b
  • 免疫细胞化学; 人类; 1:200; 图 1b
  • 免疫印迹; 人类; 图 4b
Zhao W, Luo Y, Li B, Zhang T. Tumorigenic lung tumorospheres exhibit stem-like features with significantly increased expression of CD133 and ABCG2. Mol Med Rep. 2016;14:2598-606 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:500; 图 5
  • 免疫细胞化学; 人类; 1:3000; 图 2
  • 免疫印迹; 人类; 1:1000; 图 1
Cederbye C, Palshof J, Hansen T, Duun Henriksen A, Linnemann D, Stenvang J, et al. Antibody validation and scoring guidelines for ABCG2 immunohistochemical staining in formalin-fixed paraffin-embedded colon cancer tissue. Sci Rep. 2016;6:26997 pubmed 出版商
  • 免疫印迹; 人类; 图 3
Liu Z, Hu J, Liang J, Zhou A, Li M, Yan S, et al. Far upstream element-binding protein 1 is a prognostic biomarker and promotes nasopharyngeal carcinoma progression. Cell Death Dis. 2015;6:e1920 pubmed 出版商
  • 流式细胞仪; 人类; 图 2
Su Y, Chang Y, Lin W, Liang C, Lee J. An aberrant nuclear localization of E-cadherin is a potent inhibitor of Wnt/β-catenin-elicited promotion of the cancer stem cell phenotype. Oncogenesis. 2015;4:e157 pubmed 出版商
  • 免疫细胞化学; 人类; 1:1000
Mato E, Gonzalez C, Moral A, Pérez J, Bell O, Lerma E, et al. ABCG2/BCRP gene expression is related to epithelial-mesenchymal transition inducer genes in a papillary thyroid carcinoma cell line (TPC-1). J Mol Endocrinol. 2014;52:289-300 pubmed 出版商
  • 流式细胞仪; 人类
Liu H, Zhang W, Jia Y, Yu Q, Grau G, Peng L, et al. Single-cell clones of liver cancer stem cells have the potential of differentiating into different types of tumor cells. Cell Death Dis. 2013;4:e857 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:40
  • 免疫印迹; 人类; 1:50; 图 s4
Veringa S, Biesmans D, van Vuurden D, Jansen M, Wedekind L, Horsman I, et al. In vitro drug response and efflux transporters associated with drug resistance in pediatric high grade glioma and diffuse intrinsic pontine glioma. PLoS ONE. 2013;8:e61512 pubmed 出版商
  • 免疫印迹; 大鼠
Rosales R, Monte M, Blazquez A, Briz O, Marin J. ABCC2 is involved in the hepatocyte perinuclear barrier for small organic compounds. Biochem Pharmacol. 2012;84:1651-9 pubmed 出版商
Afrouzian M, Al Lahham R, Patrikeeva S, Xu M, Fokina V, Fischer W, et al. Role of the efflux transporters BCRP and MRP1 in human placental bio-disposition of pravastatin. Biochem Pharmacol. 2018;156:467-478 pubmed 出版商
Zhang Y, Wu J, Ye M, Wang B, Sheng J, Shi B, et al. ETS1 is associated with cisplatin resistance through IKKα/NF-κB pathway in cell line MDA-MB-231. Cancer Cell Int. 2018;18:86 pubmed 出版商
Nagy B, Nagaraj C, Egemnazarov B, Kwapiszewska G, Stauber R, Avian A, et al. Lack of ABCG2 Leads to Biventricular Dysfunction and Remodeling in Response to Hypoxia. Front Physiol. 2017;8:98 pubmed 出版商
Slade R, Pisaneschi F, Nguyen Q, Smith G, Carroll L, Beckley A, et al. Identification of ABC Transporter Interaction of a Novel Cyanoquinoline Radiotracer and Implications for Tumour Imaging by Positron Emission Tomography. PLoS ONE. 2016;11:e0161427 pubmed 出版商
Seo E, Kim D, Jang I, Choi E, Shin S, Lee S, et al. Hypoxia-NOTCH1-SOX2 signaling is important for maintaining cancer stem cells in ovarian cancer. Oncotarget. 2016;7:55624-55638 pubmed 出版商
Knöspel F, Jacobs F, Freyer N, Damm G, de Bondt A, van den Wyngaert I, et al. In Vitro Model for Hepatotoxicity Studies Based on Primary Human Hepatocyte Cultivation in a Perfused 3D Bioreactor System. Int J Mol Sci. 2016;17:584 pubmed 出版商
Chen W, Zhang Y, Li Y, Zhang J, Zhang T, Fu B, et al. Constitutive expression of Wnt/β‑catenin target genes promotes proliferation and invasion of liver cancer stem cells. Mol Med Rep. 2016;13:3466-74 pubmed 出版商
Huang L, Hu C, DI Benedetto M, Varin R, Liu J, Wang L, et al. Induction of multiple drug resistance in HMEC-1 endothelial cells after long-term exposure to sunitinib. Onco Targets Ther. 2014;7:2249-55 pubmed 出版商
Huang L, Perrault C, Coelho Martins J, Hu C, Dulong C, Varna M, et al. Induction of acquired drug resistance in endothelial cells and its involvement in anticancer therapy. J Hematol Oncol. 2013;6:49 pubmed 出版商
Kim B, Fatayer H, Hanby A, Horgan K, Perry S, Valleley E, et al. Neoadjuvant chemotherapy induces expression levels of breast cancer resistance protein that predict disease-free survival in breast cancer. PLoS ONE. 2013;8:e62766 pubmed 出版商
Bejjani A, Choi M, Cassidy L, Collins D, O Brien J, Murray T, et al. RB116: an RB1+ retinoblastoma cell line expressing primitive markers. Mol Vis. 2012;18:2805-13 pubmed
Malinen M, Palokangas H, Yliperttula M, Urtti A. Peptide nanofiber hydrogel induces formation of bile canaliculi structures in three-dimensional hepatic cell culture. Tissue Eng Part A. 2012;18:2418-25 pubmed 出版商
Hoffmann S, Muller Vieira U, Biemel K, Knobeloch D, Heydel S, Lübberstedt M, et al. Analysis of drug metabolism activities in a miniaturized liver cell bioreactor for use in pharmacological studies. Biotechnol Bioeng. 2012;109:3172-81 pubmed 出版商
Xiang L, Liu Z, Huan Q, Su P, Du G, Wang Y, et al. Hypoxia-inducible factor-2a is associated with ABCG2 expression, histology-grade and Ki67 expression in breast invasive ductal carcinoma. Diagn Pathol. 2012;7:32 pubmed 出版商
Watson C, Dogruel M, Mihoreanu L, Begley D, Weksler B, Couraud P, et al. The transport of nifurtimox, an anti-trypanosomal drug, in an in vitro model of the human blood-brain barrier: evidence for involvement of breast cancer resistance protein. Brain Res. 2012;1436:111-21 pubmed 出版商
Xiang L, Su P, Xia S, Liu Z, Wang Y, Gao P, et al. ABCG2 is associated with HER-2 expression, lymph node metastasis and clinical stage in breast invasive ductal carcinoma. Diagn Pathol. 2011;6:90 pubmed 出版商
Hardwick R, Fisher C, Canet M, Scheffer G, Cherrington N. Variations in ATP-binding cassette transporter regulation during the progression of human nonalcoholic fatty liver disease. Drug Metab Dispos. 2011;39:2395-402 pubmed 出版商
Kinsella P, Clynes M, Amberger Murphy V. Imatinib and docetaxel in combination can effectively inhibit glioma invasion in an in vitro 3D invasion assay. J Neurooncol. 2011;101:189-98 pubmed 出版商
Su C, Picard P, Rathbone M, Jiang S. Guanosine-induced decrease in side population of lung cancer cells: lack of correlation with ABCG2 expression. J Biol Regul Homeost Agents. 2010;24:19-25 pubmed
Holpuch A, Hummel G, Tong M, Seghi G, Pei P, Ma P, et al. Nanoparticles for local drug delivery to the oral mucosa: proof of principle studies. Pharm Res. 2010;27:1224-36 pubmed 出版商
Shi P, Liu W, Zhou Z, He Q, Jiang W. Podoplanin and ABCG2: malignant transformation risk markers for oral lichen planus. Cancer Epidemiol Biomarkers Prev. 2010;19:844-9 pubmed 出版商
Jemnitz K, Veres Z, Tugyi R, Vereczkey L. Biliary efflux transporters involved in the clearance of rosuvastatin in sandwich culture of primary rat hepatocytes. Toxicol In Vitro. 2010;24:605-10 pubmed 出版商
Mannermaa E, Vellonen K, Ryhanen T, Kokkonen K, Ranta V, Kaarniranta K, et al. Efflux protein expression in human retinal pigment epithelium cell lines. Pharm Res. 2009;26:1785-91 pubmed 出版商
Zhang P, Zhang Y, Mao L, Zhang Z, Chen W. Side population in oral squamous cell carcinoma possesses tumor stem cell phenotypes. Cancer Lett. 2009;277:227-34 pubmed 出版商
Kis E, Nagy T, Jani M, Molnar E, Janossy J, Ujhellyi O, et al. Leflunomide and its metabolite A771726 are high affinity substrates of BCRP: implications for drug resistance. Ann Rheum Dis. 2009;68:1201-7 pubmed 出版商
Glavinas H, Kis E, Pal A, Kovács R, Jani M, Vági E, et al. ABCG2 (breast cancer resistance protein/mitoxantrone resistance-associated protein) ATPase assay: a useful tool to detect drug-transporter interactions. Drug Metab Dispos. 2007;35:1533-42 pubmed
Pal A, Mehn D, Molnar E, Gedey S, Meszaros P, Nagy T, et al. Cholesterol potentiates ABCG2 activity in a heterologous expression system: improved in vitro model to study function of human ABCG2. J Pharmacol Exp Ther. 2007;321:1085-94 pubmed
Iohara K, Zheng L, Ito M, Tomokiyo A, Matsushita K, Nakashima M. Side population cells isolated from porcine dental pulp tissue with self-renewal and multipotency for dentinogenesis, chondrogenesis, adipogenesis, and neurogenesis. Stem Cells. 2006;24:2493-503 pubmed
Janneh O, Owen A, Chandler B, Hartkoorn R, Hart C, Bray P, et al. Modulation of the intracellular accumulation of saquinavir in peripheral blood mononuclear cells by inhibitors of MRP1, MRP2, P-gp and BCRP. AIDS. 2005;19:2097-102 pubmed
Xia C, Liu N, Yang D, Miwa G, Gan L. Expression, localization, and functional characteristics of breast cancer resistance protein in Caco-2 cells. Drug Metab Dispos. 2005;33:637-43 pubmed
产品信息
目录号 :
ab3380
ItemName :
抗BCRP/ATP结合转运蛋白G超家族成员2抗体[BXP-21]
产品类型 :
一抗
宿主物种 :
小鼠
克隆性 :
单克隆
共轭标签 :
Not Conjugated
抗原修饰 :
No Modifications
克隆名称 :
BXP-21
规格 :
250微升
物种摘要 :
Hu
用途 :
Flow Cyt, ICC, ICC/IF, IHC-Fr, IHC-P
公司信息
艾博抗(上海)贸易有限公司
上海市浦东新区伽利略路338号5幢4层5401室
cn.technical@abcam.com
http://www.abcam.cn
400-628-6880 86-21-5110 5938
公司总部: 英国
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