产品简要
公司名称 :
艾博抗(上海)贸易有限公司
其他品牌 :
Epitomics, Ascent Scientific, MitoSciences
产品类型 :
抗体
产品名称 :
抗HEC1抗体[9G3]
目录 :
ab3613
规格 :
100微升
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
9G3
反应物种 :
人类, 小鼠
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀, 流式细胞仪
文章摘录数: 39
出版应用/物种/样本/稀释参考文献
  • 免疫细胞化学; 人类; 1:300; 图 s6a
Platani M, Samejima I, Samejima K, Kanemaki M, Earnshaw W. Seh1 targets GATOR2 and Nup153 to mitotic chromosomes. J Cell Sci. 2018;131: pubmed 出版商
  • 免疫细胞化学; 人类; 1:500; 图 3e
Ruppert J, Samejima K, Platani M, Molina O, Kimura H, Jeyaprakash A, et al. HP1α targets the chromosomal passenger complex for activation at heterochromatin before mitotic entry. EMBO J. 2018;37: pubmed 出版商
  • 免疫细胞化学; 人类; 图 6b
Chien J, Tsen S, Chien C, Liu H, Tung C, Lin C. ?TAT1 downregulation induces mitotic catastrophe in HeLa and A549 cells. Cell Death Discov. 2016;2:16006 pubmed 出版商
  • 免疫细胞化学; 人类; 1:200; 图 2b
Fahrenkrog B, Martinelli V, Nilles N, Fruhmann G, Chatel G, Juge S, et al. Expression of Leukemia-Associated Nup98 Fusion Proteins Generates an Aberrant Nuclear Envelope Phenotype. PLoS ONE. 2016;11:e0152321 pubmed 出版商
  • 免疫细胞化学; 人类; 1:2000; 图 s7
Iimori M, Watanabe S, Kiyonari S, Matsuoka K, Sakasai R, Saeki H, et al. Phosphorylation of EB2 by Aurora B and CDK1 ensures mitotic progression and genome stability. Nat Commun. 2016;7:11117 pubmed 出版商
  • 免疫细胞化学; 人类; 1:100
Zielinska A, Holubcová Z, Blayney M, Elder K, Schuh M. Sister kinetochore splitting and precocious disintegration of bivalents could explain the maternal age effect. elife. 2015;4:e11389 pubmed 出版商
  • 免疫细胞化学; 人类; 图 1
Ohashi A, Ohori M, Iwai K, Nambu T, Miyamoto M, Kawamoto T, et al. A Novel Time-Dependent CENP-E Inhibitor with Potent Antitumor Activity. PLoS ONE. 2015;10:e0144675 pubmed 出版商
  • 免疫细胞化学; 人类; 1:2000; 图 s2
Etemad B, Kuijt T, Kops G. Kinetochore-microtubule attachment is sufficient to satisfy the human spindle assembly checkpoint. Nat Commun. 2015;6:8987 pubmed 出版商
  • 免疫细胞化学; 人类; 图 s3a
Yan K, Li L, Wang X, Hong R, Zhang Y, Yang H, et al. The deubiquitinating enzyme complex BRISC is required for proper mitotic spindle assembly in mammalian cells. J Cell Biol. 2015;210:209-24 pubmed 出版商
  • 免疫细胞化学; 人类; 图 4d
Duminuco R, Noble J, Goody J, Sharma M, Ksander B, Roskelley C, et al. Integrin-linked kinase regulates senescence in an Rb-dependent manner in cancer cell lines. Cell Cycle. 2015;14:2924-37 pubmed 出版商
  • 免疫细胞化学; 人类; 图 6d
Liu C, Chuang J, Sung C, Mao Y. A dynein independent role of Tctex-1 at the kinetochore. Cell Cycle. 2015;14:1379-88 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 2
Milev M, Hasaj B, Saint Dic D, Snounou S, Zhao Q, Sacher M. TRAMM/TrappC12 plays a role in chromosome congression, kinetochore stability, and CENP-E recruitment. J Cell Biol. 2015;209:221-34 pubmed 出版商
  • 免疫印迹; 人类
Zhu S, Jing R, Yang Y, Huang Y, Wang X, Leng Y, et al. A motif from Lys216 to Lys222 in human BUB3 protein is a nuclear localization signal and critical for BUB3 function in mitotic checkpoint. J Biol Chem. 2015;290:11282-92 pubmed 出版商
  • 免疫细胞化学; 人类; 图 2
Chen D, Ito S, Yuan H, Hyodo T, Kadomatsu K, Hamaguchi M, et al. EML4 promotes the loading of NUDC to the spindle for mitotic progression. Cell Cycle. 2015;14:1529-39 pubmed 出版商
  • 免疫组化; 人类; 1:1000; 图 3
  • 免疫印迹; 人类; 1:2000; 图 2
Iemura K, Tanaka K. Chromokinesin Kid and kinetochore kinesin CENP-E differentially support chromosome congression without end-on attachment to microtubules. Nat Commun. 2015;6:6447 pubmed 出版商
  • 免疫细胞化学; 人类; 1:600
Silva P, Reis R, Bolanos Garcia V, Florindo C, Tavares A, Bousbaa H. Dynein-dependent transport of spindle assembly checkpoint proteins off kinetochores toward spindle poles. FEBS Lett. 2014;588:3265-73 pubmed 出版商
  • 免疫细胞化学; 人类; 1:1,000
Ballister E, Riegman M, Lampson M. Recruitment of Mad1 to metaphase kinetochores is sufficient to reactivate the mitotic checkpoint. J Cell Biol. 2014;204:901-8 pubmed 出版商
  • 免疫印迹; 人类; 1:1000
Linton A, Cheng Y, Griggs K, Schedlich L, Kirschner M, Gattani S, et al. An RNAi-based screen reveals PLK1, CDK1 and NDC80 as potential therapeutic targets in malignant pleural mesothelioma. Br J Cancer. 2014;110:510-9 pubmed 出版商
  • 免疫细胞化学; 人类; 1:200
  • 免疫印迹; 人类; 1:1000
Tan E, Caro S, Potnis A, Lanza C, Slawson C. O-linked N-acetylglucosamine cycling regulates mitotic spindle organization. J Biol Chem. 2013;288:27085-99 pubmed 出版商
  • 免疫细胞化学; 人类; 1:50
  • 免疫组化; 人类; 1:100
  • 免疫印迹; 人类; 1:1000
Mo Q, Chen P, Jin X, Chen Q, Tang L, Wang B, et al. Inhibition of Hec1 expression enhances the sensitivity of human ovarian cancer cells to paclitaxel. Acta Pharmacol Sin. 2013;34:541-8 pubmed 出版商
Takenoshita Y, Hara M, Fukagawa T. Recruitment of two Ndc80 complexes via the CENP-T pathway is sufficient for kinetochore functions. Nat Commun. 2022;13:851 pubmed 出版商
Zielinska A, Bellou E, Sharma N, Frombach A, Seres K, Gruhn J, et al. Meiotic Kinetochores Fragment into Multiple Lobes upon Cohesin Loss in Aging Eggs. Curr Biol. 2019;29:3749-3765.e7 pubmed 出版商
Ye F, Kang E, Yu C, Qian X, Jacob F, Yu C, et al. DISC1 Regulates Neurogenesis via Modulating Kinetochore Attachment of Ndel1/Nde1 during Mitosis. Neuron. 2017;96:1041-1054.e5 pubmed 出版商
Mills C, Suzuki A, Arceci A, Mo J, Duncan A, Salmon E, et al. Nucleolar and spindle-associated protein 1 (NUSAP1) interacts with a SUMO E3 ligase complex during chromosome segregation. J Biol Chem. 2017;292:17178-17189 pubmed 出版商
Gangula N, Maddika S. Interplay between the phosphatase PHLPP1 and E3 ligase RNF41 stimulates proper kinetochore assembly via the outer-kinetochore protein SGT1. J Biol Chem. 2017;292:13947-13958 pubmed 出版商
Redli P, Gasic I, Meraldi P, Nigg E, Santamaria A. The Ska complex promotes Aurora B activity to ensure chromosome biorientation. J Cell Biol. 2016;215:77-93 pubmed
Zhang X, Ling Y, Guo Y, Bai Y, Shi X, Gong F, et al. Mps1 kinase regulates tumor cell viability via its novel role in mitochondria. Cell Death Dis. 2016;7:e2292 pubmed 出版商
Chozinski T, Halpern A, Okawa H, Kim H, Tremel G, Wong R, et al. Expansion microscopy with conventional antibodies and fluorescent proteins. Nat Methods. 2016;13:485-8 pubmed 出版商
Wike C, Graves H, Hawkins R, Gibson M, Ferdinand M, Zhang T, et al. Aurora-A mediated histone H3 phosphorylation of threonine 118 controls condensin I and cohesin occupancy in mitosis. elife. 2016;5:e11402 pubmed 出版商
Zhou H, Wang T, Zheng T, Teng J, Chen J. Cep57 is a Mis12-interacting kinetochore protein involved in kinetochore targeting of Mad1-Mad2. Nat Commun. 2016;7:10151 pubmed 出版商
Patel J, Tan S, Hartshorne G, McAinsh A. Unique geometry of sister kinetochores in human oocytes during meiosis I may explain maternal age-associated increases in chromosomal abnormalities. Biol Open. 2015;5:178-84 pubmed 出版商
Minocherhomji S, Ying S, Bjerregaard V, Bursomanno S, Aleliunaite A, Wu W, et al. Replication stress activates DNA repair synthesis in mitosis. Nature. 2015;528:286-90 pubmed 出版商
Zhang P, Zhang Y, Gao K, Wang Y, Jin X, Wei Y, et al. ASPP1/2-PP1 complexes are required for chromosome segregation and kinetochore-microtubule attachments. Oncotarget. 2015;6:41550-65 pubmed 出版商
Magidson V, Paul R, Yang N, Ault J, O Connell C, Tikhonenko I, et al. Adaptive changes in the kinetochore architecture facilitate proper spindle assembly. Nat Cell Biol. 2015;17:1134-44 pubmed 出版商
BURRELL R, McClelland S, Endesfelder D, Groth P, Weller M, Shaikh N, et al. Replication stress links structural and numerical cancer chromosomal instability. Nature. 2013;494:492-496 pubmed 出版商
Wandke C, Barisic M, Sigl R, Rauch V, Wolf F, Amaro A, et al. Human chromokinesins promote chromosome congression and spindle microtubule dynamics during mitosis. J Cell Biol. 2012;198:847-63 pubmed 出版商
Varma D, Chandrasekaran S, Sundin L, Reidy K, Wan X, Chasse D, et al. Recruitment of the human Cdt1 replication licensing protein by the loop domain of Hec1 is required for stable kinetochore-microtubule attachment. Nat Cell Biol. 2012;14:593-603 pubmed 出版商
Büttner Mainik A, Parsons J, Jérôme H, Hartmann A, Lamer S, Schaaf A, et al. Production of biologically active recombinant human factor H in Physcomitrella. Plant Biotechnol J. 2011;9:373-83 pubmed 出版商
Kline S, Cheeseman I, Hori T, Fukagawa T, Desai A. The human Mis12 complex is required for kinetochore assembly and proper chromosome segregation. J Cell Biol. 2006;173:9-17 pubmed
产品信息
目录号 :
ab3613
ItemName :
抗HEC1抗体[9G3]
产品类型 :
抗体
宿主物种 :
小鼠
克隆性 :
单克隆
共轭标签 :
未共轭
克隆名称 :
9G3
规格 :
100微升
物种摘要 :
AGMk, ChHm, Hu, Ms, Pig
纯度 :
蛋白质G纯化
应用摘要 :
Flow Cyt, ICC/IF, IP, WB
公司信息
艾博抗(上海)贸易有限公司
上海市浦东新区伽利略路338号5幢4层5401室
cn.technical@abcam.com
http://www.abcam.cn
400-628-6880 86-21-5110 5938
公司总部: 英国
Abcam是全球知名的生命科学研究领域产品提供商,产品涵盖一抗、二抗、蛋白、多肽及ELISA kit。