产品简要
公司名称 :
艾博抗(上海)贸易有限公司
其他品牌 :
Epitomics, Ascent Scientific, MitoSciences
产品类型 :
抗体
产品名称 :
抗53BP1抗体
目录 :
ab36823
规格 :
100微升
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
反应物种 :
人类, 小鼠
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀, 流式细胞仪, 免疫组化-石蜡切片, 其他
文章摘录数: 31
出版应用/物种/样本/稀释参考文献
  • 免疫细胞化学; 人类; 1:1000; 图 5b
Baquero J, Benitez Buelga C, Rajagopal V, Zhenjun Z, Torres Ruiz R, Muller S, et al. Small molecule inhibitor of OGG1 blocks oxidative DNA damage repair at telomeres and potentiates methotrexate anticancer effects. Sci Rep. 2021;11:3490 pubmed 出版商
  • 免疫印迹; 人类
Lochab S, Singh Y, Sengupta S, Nandicoori V. Mycobacterium tuberculosis exploits host ATM kinase for survival advantage through SecA2 secretome. elife. 2020;9: pubmed 出版商
  • 免疫细胞化学; 人类; 图 2b
Tepper S, Mortusewicz O, Członka E, Bello A, Schmidt A, Jeschke J, et al. Restriction of AID activity and somatic hypermutation by PARP-1. Nucleic Acids Res. 2019;47:7418-7429 pubmed 出版商
  • 免疫印迹; 人类; 1:20,000; 图 5n
Ma S, Yang D, Liu Y, Wang Y, Lin T, Li Y, et al. LncRNA BANCR promotes tumorigenesis and enhances adriamycin resistance in colorectal cancer. Aging (Albany NY). 2018;10:2062-2078 pubmed 出版商
  • 免疫组化; 小鼠; 图 6a
Zhou Z, Wang L, Ge F, Gong P, Wang H, Wang F, et al. Pold3 is required for genomic stability and telomere integrity in embryonic stem cells and meiosis. Nucleic Acids Res. 2018;46:3468-3486 pubmed 出版商
  • 免疫细胞化学; 人类; 图 4
Pal D, Pertot A, Shirole N, Yao Z, Anaparthy N, Garvin T, et al. TGF-β reduces DNA ds-break repair mechanisms to heighten genetic diversity and adaptability of CD44+/CD24- cancer cells. elife. 2017;6: pubmed 出版商
  • 免疫细胞化学; 小鼠; 图 s5a
Kariolis M, Miao Y, Diep A, Nash S, Olcina M, Jiang D, et al. Inhibition of the GAS6/AXL pathway augments the efficacy of chemotherapies. J Clin Invest. 2017;127:183-198 pubmed 出版商
  • 其他; 人类; 图 5
  • 免疫细胞化学; 人类; 图 3
Zhang X, Ye C, Sun F, Wei W, Hu B, Wang J. Both Complexity and Location of DNA Damage Contribute to Cellular Senescence Induced by Ionizing Radiation. PLoS ONE. 2016;11:e0155725 pubmed 出版商
  • 免疫细胞化学; 人类; 图 2
  • 免疫印迹; 人类; 图 2
Onyango D, Howard S, Neherin K, Yanez D, Stark J. Tetratricopeptide repeat factor XAB2 mediates the end resection step of homologous recombination. Nucleic Acids Res. 2016;44:5702-16 pubmed 出版商
  • 免疫细胞化学; 人类; 1:500; 图 5
Ercilla A, Llopis A, Feu S, Aranda S, Ernfors P, Freire R, et al. New origin firing is inhibited by APC/CCdh1 activation in S-phase after severe replication stress. Nucleic Acids Res. 2016;44:4745-62 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:100; 图 5a
Kim S, Bozeman R, Kaisani A, Kim W, Zhang L, Richardson J, et al. Radiation promotes colorectal cancer initiation and progression by inducing senescence-associated inflammatory responses. Oncogene. 2016;35:3365-75 pubmed 出版商
  • 免疫细胞化学; 人类
Marchesini M, Matocci R, Tasselli L, Cambiaghi V, Orleth A, Furia L, et al. PML is required for telomere stability in non-neoplastic human cells. Oncogene. 2016;35:1811-21 pubmed 出版商
Xu S, Wang X, Wang T, Lin Z, Hu Y, Huang Z, et al. Flavonoids from Rosaroxburghii Tratt prevent reactive oxygen species-mediated DNA damage in thymus cells both combined with and without PARP-1 expression after exposure to radiation in vivo. Aging (Albany NY). 2020;12:16368-16389 pubmed 出版商
Sharma S, Munger K. Expression of the Long Noncoding RNA DINO in Human Papillomavirus-Positive Cervical Cancer Cells Reactivates the Dormant TP53 Tumor Suppressor through ATM/CHK2 Signaling. MBio. 2020;11: pubmed 出版商
Tsai L, Lopezcolorado F, Bhargava R, Mendez Dorantes C, Jahanshir E, Stark J. RNF8 has both KU-dependent and independent roles in chromosomal break repair. Nucleic Acids Res. 2020;48:6032-6052 pubmed 出版商
Salvador Moreno N, Liu J, Haas K, Parker L, Chakraborty C, Kron S, et al. The nuclear structural protein NuMA is a negative regulator of 53BP1 in DNA double-strand break repair. Nucleic Acids Res. 2019;47:2703-2715 pubmed 出版商
Guha M, Srinivasan S, Johnson F, Ruthel G, Guja K, Garcia Diaz M, et al. hnRNPA2 mediated acetylation reduces telomere length in response to mitochondrial dysfunction. PLoS ONE. 2018;13:e0206897 pubmed 出版商
Róna G, Roberti D, Yin Y, Pagan J, Homer H, Sassani E, et al. PARP1-dependent recruitment of the FBXL10-RNF68-RNF2 ubiquitin ligase to sites of DNA damage controls H2A.Z loading. elife. 2018;7: pubmed 出版商
Lyu G, Guan Y, Zhang C, Zong L, Sun L, Huang X, et al. TGF-β signaling alters H4K20me3 status via miR-29 and contributes to cellular senescence and cardiac aging. Nat Commun. 2018;9:2560 pubmed 出版商
Mendez Dorantes C, Bhargava R, Stark J. Repeat-mediated deletions can be induced by a chromosomal break far from a repeat, but multiple pathways suppress such rearrangements. Genes Dev. 2018;32:524-536 pubmed 出版商
Tiwari A, Addis Jones O, Chan K. 53BP1 can limit sister-chromatid rupture and rearrangements driven by a distinct ultrafine DNA bridging-breakage process. Nat Commun. 2018;9:677 pubmed 出版商
Yang Y, Lei T, Du S, Tong R, Wang H, Yang J, et al. Nuclear GSK3β induces DNA double-strand break repair by phosphorylating 53BP1 in glioblastoma. Int J Oncol. 2018;52:709-720 pubmed 出版商
Onyango D, Lee G, Stark J. PRPF8 is important for BRCA1-mediated homologous recombination. Oncotarget. 2017;8:93319-93337 pubmed 出版商
Zhao W, Steinfeld J, Liang F, Chen X, Maranon D, Jian Ma C, et al. BRCA1-BARD1 promotes RAD51-mediated homologous DNA pairing. Nature. 2017;550:360-365 pubmed 出版商
Hollingworth R, Horniblow R, Forrest C, Stewart G, Grand R. Localization of Double-Strand Break Repair Proteins to Viral Replication Compartments following Lytic Reactivation of Kaposi's Sarcoma-Associated Herpesvirus. J Virol. 2017;91: pubmed 出版商
Vidi P, Anderson K, Chen H, Anderson R, Salvador Moreno N, Mora D, et al. Personal samplers of bioavailable pesticides integrated with a hair follicle assay of DNA damage to assess environmental exposures and their associated risks in children. Mutat Res. 2017;822:27-33 pubmed 出版商
Fu Y, Zhou Z, Wang H, Gong P, Guo R, Wang J, et al. IFITM1 suppresses expression of human endogenous retroviruses in human embryonic stem cells. FEBS Open Bio. 2017;7:1102-1110 pubmed 出版商
King H, Brend T, Payne H, Wright A, Ward T, Patel K, et al. RAD51 Is a Selective DNA Repair Target to Radiosensitize Glioma Stem Cells. Stem Cell Reports. 2017;8:125-139 pubmed 出版商
Bhargava R, Carson C, Lee G, Stark J. Contribution of canonical nonhomologous end joining to chromosomal rearrangements is enhanced by ATM kinase deficiency. Proc Natl Acad Sci U S A. 2017;114:728-733 pubmed 出版商
Luebben S, Kawabata T, Johnson C, O Sullivan M, Shima N. A concomitant loss of dormant origins and FANCC exacerbates genome instability by impairing DNA replication fork progression. Nucleic Acids Res. 2014;42:5605-15 pubmed 出版商
Munoz M, Laulier C, Gunn A, Cheng A, Robbiani D, Nussenzweig A, et al. RING finger nuclear factor RNF168 is important for defects in homologous recombination caused by loss of the breast cancer susceptibility factor BRCA1. J Biol Chem. 2012;287:40618-28 pubmed 出版商
产品信息
目录号 :
ab36823
ItemName :
抗53BP1抗体
产品类型 :
一抗
宿主物种 :
克隆性 :
多克隆
共轭标签 :
Not Conjugated
抗原修饰 :
No Modifications
规格 :
100微升
物种摘要 :
Hu, Ms
用途 :
Flow Cyt, ICC/IF, IHC-P, IP, WB
公司信息
艾博抗(上海)贸易有限公司
上海市浦东新区伽利略路338号5幢4层5401室
cn.technical@abcam.com
http://www.abcam.cn
400-628-6880 86-21-5110 5938
公司总部: 英国
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