产品简要
公司名称 :
艾博抗(上海)贸易有限公司
其他品牌 :
Epitomics, Ascent Scientific, MitoSciences
产品类型 :
抗体
产品名称 :
抗Cdk5抗体[EP715Y]
目录 :
ab40773
规格 :
10微升, 100微升
克隆性 :
单克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
克隆名称 :
EP715Y
反应物种 :
人类, 小鼠, 大鼠,
应用 :
免疫印迹, 免疫细胞化学, 免疫沉淀, 流式细胞仪, 免疫组化-石蜡切片, 免疫组化-冰冻切片
文章摘录数: 12
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 人类; 1:1000; 图 s4h
Hu D, Sun X, Magpusao A, Fedorov Y, Thompson M, Wang B, et al. Small-molecule suppression of calpastatin degradation reduces neuropathology in models of Huntington's disease. Nat Commun. 2021;12:5305 pubmed 出版商
  • 免疫印迹; 小鼠; 1:500; 图 2d
Yang X, Ding Y, Yang M, Yu L, Hu Y, Deng Y. Nestin Improves Preeclampsia-Like Symptoms by Inhibiting Activity of Cyclin-Dependent Kinase 5. Kidney Blood Press Res. 2018;43:616-627 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 6
Yu H, Xie J, Li B, Sun Y, Gao Q, Ding Z, et al. TIGAR regulates DNA damage and repair through pentosephosphate pathway and Cdk5-ATM pathway. Sci Rep. 2015;5:9853 pubmed 出版商
  • 免疫印迹; 大鼠; 1:2000
Liu X, Liu Y, Zhang J, Zhang W, Sun Y, Gu X, et al. Intrathecal administration of roscovitine prevents remifentanil-induced postoperative hyperalgesia and decreases the phosphorylation of N-methyl-D-aspartate receptor and metabotropic glutamate receptor 5 in spinal cord. Brain Res Bull. 2014;106:9-16 pubmed 出版商
  • 免疫组化-冰冻切片; 大鼠; 1:200
  • 免疫沉淀; 大鼠
  • 免疫印迹; 大鼠
Zhang H, Zhang X, Wang W, Xue Q, Lu H, Huang J, et al. Increased synaptophysin is involved in inflammation-induced heat hyperalgesia mediated by cyclin-dependent kinase 5 in rats. PLoS ONE. 2012;7:e46666 pubmed 出版商
Zeng P, Fang M, Zhao H, Guo J. A network pharmacology approach to uncover the key ingredients in Ginkgo Folium and their anti-Alzheimer's disease mechanisms. Aging (Albany NY). 2021;13:18993-19012 pubmed 出版商
Zhu L, Ding R, Zhang J, Zhang J, Lin Z. Cyclin-dependent kinase 5 acts as a promising biomarker in clear cell Renal Cell Carcinoma. BMC Cancer. 2019;19:698 pubmed 出版商
Xie W, Liu C, Wu D, Li Z, Li C, Zhang Y. Phosphorylation of kinase insert domain receptor by cyclin-dependent kinase 5 at serine 229 is associated with invasive behavior and poor prognosis in prolactin pituitary adenomas. Oncotarget. 2016;7:50883-50894 pubmed 出版商
Sadleir K, Vassar R. Cdk5 protein inhibition and A?42 increase BACE1 protein level in primary neurons by a post-transcriptional mechanism: implications of CDK5 as a therapeutic target for Alzheimer disease. J Biol Chem. 2012;287:7224-35 pubmed 出版商
Eggers J, Grandgenett P, Collisson E, Lewallen M, Tremayne J, Singh P, et al. Cyclin-dependent kinase 5 is amplified and overexpressed in pancreatic cancer and activated by mutant K-Ras. Clin Cancer Res. 2011;17:6140-50 pubmed 出版商
Abdullah C, Wang X, Becker D. Expression analysis and molecular targeting of cyclin-dependent kinases in advanced melanoma. Cell Cycle. 2011;10:977-88 pubmed
Coras R, Siebzehnrubl F, Pauli E, Huttner H, Njunting M, Kobow K, et al. Low proliferation and differentiation capacities of adult hippocampal stem cells correlate with memory dysfunction in humans. Brain. 2010;133:3359-72 pubmed 出版商
产品信息
目录号 :
ab40773
ItemName :
抗Cdk5抗体[EP715Y]
类别 :
抗体
宿主 :
克隆性 :
单克隆
共轭标签 :
未共轭
克隆名称 :
EP715Y
规格 :
10微升, 100微升
物种摘要 :
Chk, Hu, Ms, Rat
应用摘要 :
Flow Cyt, ICC, IHC-Fr, IHC-P, IP, WB
公司信息
艾博抗(上海)贸易有限公司
上海市浦东新区伽利略路338号5幢4层5401室
cn.technical@abcam.com
http://www.abcam.cn
400-628-6880 86-21-5110 5938
公司总部: 英国
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