产品简要
公司名称 :
艾博抗(上海)贸易有限公司
其他品牌 :
Epitomics, Ascent Scientific, MitoSciences
产品类型 :
抗体
产品名称 :
抗Smad3抗体[EP568Y]
目录 :
ab40854
规格 :
10微升, 100微升
克隆性 :
单克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
克隆名称 :
EP568Y
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学, 免疫沉淀, 流式细胞仪, 免疫组化-石蜡切片, In-Cell Western, 其他, 免疫印迹基因敲除验证
文章摘录数: 41
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 大鼠; 1:1000; 图 2a
Liang L, Li S, Liu H, Mao Y, Liu L, Zhang X, et al. Blood glucose control contributes to protein stability of Ski-related novel protein N in a rat model of diabetes. Exp Ther Med. 2021;22:1341 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 10c
Ye Q, Chen H, Ma H, Xiang X, Hu S, Xia C, et al. Xiaoyu Xiezhuo Drink Protects against Ischemia-Reperfusion Acute Kidney Injury in Aged Mice through Inhibiting the TGF-β1/Smad3 and HIF1 Signaling Pathways. Biomed Res Int. 2021;2021:9963732 pubmed 出版商
  • 免疫印迹; 人类; 图 4a
Fang L, Wang W, Chen J, Zuo A, Gao H, Yan T, et al. Osthole Attenuates Bleomycin-Induced Pulmonary Fibrosis by Modulating NADPH Oxidase 4-Derived Oxidative Stress in Mice. Oxid Med Cell Longev. 2021;2021:3309944 pubmed 出版商
  • 免疫印迹; 小鼠; 0.25 ug/ml; 图 4d
Wu X, Shu L, Zhang Z, Li J, Zong J, Cheong L, et al. Adipocyte Fatty Acid Binding Protein Promotes the Onset and Progression of Liver Fibrosis via Mediating the Crosstalk between Liver Sinusoidal Endothelial Cells and Hepatic Stellate Cells. Adv Sci (Weinh). 2021;8:e2003721 pubmed 出版商
  • 免疫印迹; 大鼠; 1:1000; 图 7b
Han Y, Liu Y, Zhang B, Yin G. Exosomal circRNA 0001445 promotes glioma progression through miRNA-127-5p/SNX5 pathway. Aging (Albany NY). 2021;13:13287-13299 pubmed 出版商
  • 免疫印迹; 大鼠; 1:1000; 图 7b
Yao S, Wang L, Chen Q, Lu T, Pu X, Luo C. The effect of mild hypothermia plus rutin on the treatment of spinal cord injury and inflammatory factors by repressing TGF-β/smad pathway. Acta Cir Bras. 2021;36:e360307 pubmed 出版商
  • 免疫印迹; 人类; 图 7i
Fell S, Wang Z, Blanchard A, Nanthakumar C, Griffin M. Transglutaminase 2: a novel therapeutic target for idiopathic pulmonary fibrosis using selective small molecule inhibitors. Amino Acids. 2021;53:205-217 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 6a
Chen Y, Jhao P, Hung C, Wu Y, Lin S, Chiang W, et al. Endoplasmic reticulum protein TXNDC5 promotes renal fibrosis by enforcing TGF-β signaling in kidney fibroblasts. J Clin Invest. 2021;131: pubmed 出版商
  • 免疫印迹; 小鼠; 1:2000; 图 4a
Mehta N, Li R, Zhang D, Soomro A, He J, Zhang I, et al. miR299a-5p promotes renal fibrosis by suppressing the antifibrotic actions of follistatin. Sci Rep. 2021;11:88 pubmed 出版商
  • 免疫印迹基因敲除验证; 人类; 1:1000; 图 1c
Gori I, George R, Purkiss A, Strohbuecker S, Randall R, Ogrodowicz R, et al. Mutations in SKI in Shprintzen-Goldberg syndrome lead to attenuated TGF-β responses through SKI stabilization. elife. 2021;10: pubmed 出版商
  • 免疫印迹; 人类; 图 4c
Herberg S, McDermott A, Dang P, Alt D, Tang R, Dawahare J, et al. Combinatorial morphogenetic and mechanical cues to mimic bone development for defect repair. Sci Adv. 2019;5:eaax2476 pubmed 出版商
  • 免疫印迹; 小鼠; 图 3d
Liu F, Fan D, Yang Z, Tang N, Guo Z, Ma S, et al. TLR9 is essential for HMGB1-mediated post-myocardial infarction tissue repair through affecting apoptosis, cardiac healing, and angiogenesis. Cell Death Dis. 2019;10:480 pubmed 出版商
  • 免疫印迹; 人类; 图 3e
Guo H, Ci X, Ahmed M, Hua J, Soares F, Lin D, et al. ONECUT2 is a driver of neuroendocrine prostate cancer. Nat Commun. 2019;10:278 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 3d, 4c
Zhang X, Zhang M, Wang C. Loss of LRRC25 accelerates pathological cardiac hypertrophy through promoting fibrosis and inflammation regulated by TGF-β1. Biochem Biophys Res Commun. 2018;506:137-144 pubmed 出版商
  • 免疫印迹基因敲除验证; 小鼠; 图 s1c
Senft A, Costello I, King H, Mould A, Bikoff E, Robertson E. Combinatorial Smad2/3 Activities Downstream of Nodal Signaling Maintain Embryonic/Extra-Embryonic Cell Identities during Lineage Priming. Cell Rep. 2018;24:1977-1985.e7 pubmed 出版商
  • 免疫沉淀; 人类; 图 6a
Castanotto D, Zhang X, Alluin J, Zhang X, Rüger J, Armstrong B, et al. A stress-induced response complex (SIRC) shuttles miRNAs, siRNAs, and oligonucleotides to the nucleus. Proc Natl Acad Sci U S A. 2018;115:E5756-E5765 pubmed 出版商
  • 其他; 人类; 图 4c
Ng P, Li J, Jeong K, Shao S, Chen H, Tsang Y, et al. Systematic Functional Annotation of Somatic Mutations in Cancer. Cancer Cell. 2018;33:450-462.e10 pubmed 出版商
  • 免疫组化; 小鼠; 1:1000; 图 1c
  • 免疫组化; 人类; 1:1000; 图 3a
  • 免疫印迹; 人类; 图 4a
Sato F, Kohsaka A, Takahashi K, Otao S, Kitada Y, Iwasaki Y, et al. Smad3 and Bmal1 regulate p21 and S100A4 expression in myocardial stromal fibroblasts via TNF-?. Histochem Cell Biol. 2017;148:617-624 pubmed 出版商
  • 免疫印迹; 大鼠; 1:1000; 图 1c
Wang Y, Shen R, Han B, Li Z, Xiong L, Zhang F, et al. Notch signaling mediated by TGF-?/Smad pathway in concanavalin A-induced liver fibrosis in rats. World J Gastroenterol. 2017;23:2330-2336 pubmed 出版商
  • 免疫印迹; 人类; 图 4
Liu P, Wang C, Ma C, Wu Q, Zhang W, Lao G. MicroRNA-23a regulates epithelial-to-mesenchymal transition in endometrial endometrioid adenocarcinoma by targeting SMAD3. Cancer Cell Int. 2016;16:67 pubmed 出版商
  • 免疫印迹; 人类; 1:5000; 图 5c
Omata M, Doke Y, Yamada C, Kawashima K, Sho R, Enomoto K, et al. Hepatocyte Nuclear Factor-1β Induces Redifferentiation of Dedifferentiated Tubular Epithelial Cells. PLoS ONE. 2016;11:e0154912 pubmed 出版商
  • 免疫印迹; 人类; 1:2500; 图 4
Xu X, Tan X, Hulshoff M, Wilhelmi T, Zeisberg M, Zeisberg E. Hypoxia-induced endothelial-mesenchymal transition is associated with RASAL1 promoter hypermethylation in human coronary endothelial cells. FEBS Lett. 2016;590:1222-33 pubmed 出版商
  • 免疫印迹; 小鼠; 图 3
Li S, Wang F, Yang Y, Tiao M, Chuang J, Huang Y. Microarray Study of Pathway Analysis Expression Profile Associated with MicroRNA-29a with Regard to Murine Cholestatic Liver Injuries. Int J Mol Sci. 2016;17:324 pubmed 出版商
  • 免疫印迹; 人类; 图 1
Bartscht T, Rosien B, Rades D, Kaufmann R, Biersack H, Lehnert H, et al. Dasatinib blocks transcriptional and promigratory responses to transforming growth factor-beta in pancreatic adenocarcinoma cells through inhibition of Smad signalling: implications for in vivo mode of action. Mol Cancer. 2015;14:199 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 3
Waning D, Mohammad K, Reiken S, Xie W, Andersson D, John S, et al. Excess TGF-β mediates muscle weakness associated with bone metastases in mice. Nat Med. 2015;21:1262-1271 pubmed 出版商
  • 免疫印迹; 小鼠; 图 7b
Huang Y, Tiao M, Huang L, Chuang J, Kuo K, Yang Y, et al. Activation of Mir-29a in Activated Hepatic Stellate Cells Modulates Its Profibrogenic Phenotype through Inhibition of Histone Deacetylases 4. PLoS ONE. 2015;10:e0136453 pubmed 出版商
  • 免疫印迹; 人类; 1:500; 图 5
Aspalter I, Gordon E, Dubrac A, Ragab A, Narloch J, Vizan P, et al. Alk1 and Alk5 inhibition by Nrp1 controls vascular sprouting downstream of Notch. Nat Commun. 2015;6:7264 pubmed 出版商
  • 免疫印迹; 人类
Chen R, Xu B, Chen S, Chen S, Zhang T, Ren J, et al. Effect of oridonin-mediated hallmark changes on inflammatory pathways in human pancreatic cancer (BxPC-3) cells. World J Gastroenterol. 2014;20:14895-903 pubmed 出版商
  • In-Cell Western; 人类
Marino F, Risbridger G, Gold E. The inhibin/activin signalling pathway in human gonadal and adrenal cancers. Mol Hum Reprod. 2014;20:1223-37 pubmed 出版商
  • 免疫细胞化学; 人类
Isogaya K, Koinuma D, Tsutsumi S, Saito R, Miyazawa K, Aburatani H, et al. A Smad3 and TTF-1/NKX2-1 complex regulates Smad4-independent gene expression. Cell Res. 2014;24:994-1008 pubmed 出版商
Morice S, Danieau G, Tesfaye R, Mullard M, Brion R, Dupuy M, et al. Involvement of the TGF-β Signaling Pathway in the Development of YAP-Driven Osteosarcoma Lung Metastasis. Front Oncol. 2021;11:765711 pubmed 出版商
Sun Y, Cao B, Zhou J. Roles of DANCR/microRNA-518a-3p/MDMA ceRNA network in the growth and malignant behaviors of colon cancer cells. BMC Cancer. 2020;20:434 pubmed 出版商
Yuan Y, Wang J, Xu M, Zhang Y, Wang Z, Liang L, et al. 20(S)-ginsenoside Rh2 as agent for the treatment of LMN-CRC via regulating epithelial-mesenchymal transition. Biosci Rep. 2020;40: pubmed 出版商
Gu R, Huang Z, Liu H, Qing Q, Zhuan Z, Yang L, et al. Moracin attenuates LPS-induced inflammation in nucleus pulposus cells via Nrf2/HO-1 and NF-κB/TGF-β pathway. Biosci Rep. 2019;39: pubmed 出版商
Chen J, Yi X, Gu P, Gao S. The role of KDR in intrauterine adhesions may involve the TGF-β1/Smads signaling pathway. Braz J Med Biol Res. 2019;52:e8324 pubmed 出版商
Papoutsoglou P, Tsubakihara Y, Caja L, Morén A, Pallis P, Ameur A, et al. The TGFB2-AS1 lncRNA Regulates TGF-β Signaling by Modulating Corepressor Activity. Cell Rep. 2019;28:3182-3198.e11 pubmed 出版商
Ungefroren H, Otterbein H, Fiedler C, Mihara K, Hollenberg M, Gieseler F, et al. RAC1B Suppresses TGF-β1-Dependent Cell Migration in Pancreatic Carcinoma Cells through Inhibition of the TGF-β Type I Receptor ALK5. Cancers (Basel). 2019;11: pubmed 出版商
Yao J, Zhang X, Li J, Zhao D, Gao B, Zhou H, et al. Silencing TRIP13 inhibits cell growth and metastasis of hepatocellular carcinoma by activating of TGF-β1/smad3. Cancer Cell Int. 2018;18:208 pubmed 出版商
Kawasaki N, Miwa T, Hokari S, Sakurai T, Ohmori K, Miyauchi K, et al. Long noncoding RNA NORAD regulates transforming growth factor-β signaling and epithelial-to-mesenchymal transition-like phenotype. Cancer Sci. 2018;109:2211-2220 pubmed 出版商
Han Y, Yue L, Wei M, Ren X, Shao Z, Zhang L, et al. Mesenchymal Cell Reprogramming in Experimental MPLW515L Mouse Model of Myelofibrosis. PLoS ONE. 2017;12:e0166014 pubmed 出版商
Ungefroren H, Sebens S, Giehl K, Helm O, Groth S, Fandrich F, et al. Rac1b negatively regulates TGF-?1-induced cell motility in pancreatic ductal epithelial cells by suppressing Smad signalling. Oncotarget. 2014;5:277-90 pubmed
产品信息
目录号 :
ab40854
ItemName :
抗Smad3抗体[EP568Y]
类别 :
抗体
宿主 :
克隆性 :
单克隆
共轭标签 :
未共轭
克隆名称 :
EP568Y
规格 :
10微升, 100微升
物种摘要 :
Hu, Ms, Rat
应用摘要 :
Flow Cyt, ICC/IF, IHC-P, sELISA, WB
公司信息
艾博抗(上海)贸易有限公司
上海市浦东新区伽利略路338号5幢4层5401室
cn.technical@abcam.com
http://www.abcam.cn
400-628-6880 86-21-5110 5938
公司总部: 英国
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