出版应用/物种/样本/稀释 | 参考文献 |
---|
| Wan L, Chong S, Xuan F, Liang A, Cui X, Gates L, et al. Impaired cell fate through gain-of-function mutations in a chromatin reader. Nature. 2020;577:121-126 pubmed 出版商
|
| Montaldo N, Bordin D, Brambilla A, Rösinger M, Fordyce Martin S, Bjørås K, et al. Alkyladenine DNA glycosylase associates with transcription elongation to coordinate DNA repair with gene expression. Nat Commun. 2019;10:5460 pubmed 出版商
|
| Yoshimi A, Lin K, Wiseman D, Rahman M, Pastore A, Wang B, et al. Coordinated alterations in RNA splicing and epigenetic regulation drive leukaemogenesis. Nature. 2019;574:273-277 pubmed 出版商
|
| Sun Y, Liu Z, Cao X, Lu Y, Mi Z, He C, et al. Activation of P-TEFb by cAMP-PKA signaling in autosomal dominant polycystic kidney disease. Sci Adv. 2019;5:eaaw3593 pubmed 出版商
|
| Donnio L, Lagarou A, Sueur G, Mari P, Giglia Mari G. CSB-Dependent Cyclin-Dependent Kinase 9 Degradation and RNA Polymerase II Phosphorylation during Transcription-Coupled Repair. Mol Cell Biol. 2019;39: pubmed 出版商
|
| Leoz M, Kukanja P, Luo Z, Huang F, Cary D, Peterlin B, et al. HEXIM1-Tat chimera inhibits HIV-1 replication. PLoS Pathog. 2018;14:e1007402 pubmed 出版商
|
| Stewart E, McEvoy J, Wang H, Chen X, Honnell V, Ocarz M, et al. Identification of Therapeutic Targets in Rhabdomyosarcoma through Integrated Genomic, Epigenomic, and Proteomic Analyses. Cancer Cell. 2018;34:411-426.e19 pubmed 出版商
|
| Yu F, Shi G, Cheng S, Chen J, Wu S, Wang Z, et al. SUMO suppresses and MYC amplifies transcription globally by regulating CDK9 sumoylation. Cell Res. 2018;28:670-685 pubmed 出版商
|
| Hoshii T, Cifani P, Feng Z, Huang C, Koche R, Chen C, et al. A Non-catalytic Function of SETD1A Regulates Cyclin K and the DNA Damage Response. Cell. 2018;172:1007-1021.e17 pubmed 出版商
|
| Czimmerer Z, Dániel B, Horvath A, Rückerl D, Nagy G, Kiss M, et al. The Transcription Factor STAT6 Mediates Direct Repression of Inflammatory Enhancers and Limits Activation of Alternatively Polarized Macrophages. Immunity. 2018;48:75-90.e6 pubmed 出版商
|
- 免疫组化; fruit fly ; 1:100; 表 s2
| Zenk F, Loeser E, Schiavo R, Kilpert F, Bogdanović O, Iovino N. Germ line-inherited H3K27me3 restricts enhancer function during maternal-to-zygotic transition. Science. 2017;357:212-216 pubmed 出版商
|
| Wan L, Wen H, Li Y, Lyu J, Xi Y, Hoshii T, et al. ENL links histone acetylation to oncogenic gene expression in acute myeloid leukaemia. Nature. 2017;543:265-269 pubmed 出版商
|
- 免疫细胞化学; 小鼠; 图 6ci
- 免疫印迹; 小鼠; 图 4
| Soboleva T, Parker B, Nekrasov M, Hart Smith G, Tay Y, Tng W, et al. A new link between transcriptional initiation and pre-mRNA splicing: The RNA binding histone variant H2A.B. PLoS Genet. 2017;13:e1006633 pubmed 出版商
|
| Viscarra J, Wang Y, Hong I, Sul H. Transcriptional activation of lipogenesis by insulin requires phosphorylation of MED17 by CK2. Sci Signal. 2017;10: pubmed 出版商
|
| Mathew R, Tatarakis A, Rudenko A, Johnson Venkatesh E, Yang Y, Murphy E, et al. A microRNA negative feedback loop downregulates vesicle transport and inhibits fear memory. elife. 2016;5: pubmed 出版商
|
| Harrod A, Fulton J, Nguyen V, Periyasamy M, Ramos Garcia L, Lai C, et al. Genomic modelling of the ESR1 Y537S mutation for evaluating function and new therapeutic approaches for metastatic breast cancer. Oncogene. 2017;36:2286-2296 pubmed 出版商
|
| Chung H, Xu C, Fuchs A, Mund A, Lange M, Staege H, et al. PHF13 is a molecular reader and transcriptional co-regulator of H3K4me2/3. elife. 2016;5: pubmed 出版商
|
| Onyango D, Howard S, Neherin K, Yanez D, Stark J. Tetratricopeptide repeat factor XAB2 mediates the end resection step of homologous recombination. Nucleic Acids Res. 2016;44:5702-16 pubmed 出版商
|
| Akan I, Love D, Harwood K, Bond M, Hanover J. Drosophila O-GlcNAcase Deletion Globally Perturbs Chromatin O-GlcNAcylation. J Biol Chem. 2016;291:9906-19 pubmed 出版商
|
| Boulding T, Wu F, McCuaig R, Dunn J, Sutton C, Hardy K, et al. Differential Roles for DUSP Family Members in Epithelial-to-Mesenchymal Transition and Cancer Stem Cell Regulation in Breast Cancer. PLoS ONE. 2016;11:e0148065 pubmed 出版商
|
| Ancelin K, Syx L, Borensztein M, Ranisavljevic N, Vassilev I, Briseño Roa L, et al. Maternal LSD1/KDM1A is an essential regulator of chromatin and transcription landscapes during zygotic genome activation. elife. 2016;5: pubmed 出版商
|
| Tamaoki K, Okada R, Ishihara A, Shiojiri N, Mochizuki K, Goda T, et al. Morphological, biochemical, transcriptional and epigenetic responses to fasting and refeeding in intestine of Xenopus laevis. Cell Biosci. 2016;6:2 pubmed 出版商
|
| Mortusewicz O, Evers B, Helleday T. PC4 promotes genome stability and DNA repair through binding of ssDNA at DNA damage sites. Oncogene. 2016;35:761-70 pubmed 出版商
|
| Himeda C, Jones T, Jones P. Targeted epigenetic repression by CRISPR/dSaCas9 suppresses pathogenic DUX4-fl expression in FSHD. Mol Ther Methods Clin Dev. 2021;20:298-311 pubmed 出版商
|
| Ding L, Paszkowski Rogacz M, Mircetic J, Chakraborty D, Buchholz F. The Paf1 complex positively regulates enhancer activity in mouse embryonic stem cells. Life Sci Alliance. 2021;4: pubmed 出版商
|
| Zhang M, Lai Y, Krupalnik V, Guo P, Guo X, Zhou J, et al. β-Catenin safeguards the ground state of mousepluripotency by strengthening the robustness of the transcriptional apparatus. Sci Adv. 2020;6:eaba1593 pubmed 出版商
|
| Nava M, Miroshnikova Y, Biggs L, Whitefield D, Metge F, Boucas J, et al. Heterochromatin-Driven Nuclear Softening Protects the Genome against Mechanical Stress-Induced Damage. Cell. 2020;181:800-817.e22 pubmed 出版商
|
| Apelt K, Zoutendijk I, Gout D, Wondergem A, van den Heuvel D, Luijsterburg M. Human HMGN1 and HMGN2 are not required for transcription-coupled DNA repair. Sci Rep. 2020;10:4332 pubmed 出版商
|
| Purman C, Collins P, Porter S, Saini A, Gupta H, Sleckman B, et al. Regional Gene Repression by DNA Double-Strand Breaks in G1 Phase Cells. Mol Cell Biol. 2019;39: pubmed 出版商
|
| Sato Y, Hilbert L, Oda H, Wan Y, Heddleston J, Chew T, et al. Histone H3K27 acetylation precedes active transcription during zebrafish zygotic genome activation as revealed by live-cell analysis. Development. 2019;146: pubmed 出版商
|
| Babos K, Galloway K, Kisler K, Zitting M, Li Y, Shi Y, et al. Mitigating Antagonism between Transcription and Proliferation Allows Near-Deterministic Cellular Reprogramming. Cell Stem Cell. 2019;25:486-500.e9 pubmed 出版商
|
| Wu S, Naar A. SREBP1-dependent de novo fatty acid synthesis gene expression is elevated in malignant melanoma and represents a cellular survival trait. Sci Rep. 2019;9:10369 pubmed 出版商
|
| Blake D, Vaseva A, Hodge R, Kline M, Gilbert T, Tyagi V, et al. Application of a MYC degradation screen identifies sensitivity to CDK9 inhibitors in KRAS-mutant pancreatic cancer. Sci Signal. 2019;12: pubmed 出版商
|
| Zierhut C, Yamaguchi N, Paredes M, Luo J, Carroll T, Funabiki H. The Cytoplasmic DNA Sensor cGAS Promotes Mitotic Cell Death. Cell. 2019;178:302-315.e23 pubmed 出版商
|
| Chen C, Shu J, Li C, Thapa R, Nguyen V, Yu K, et al. RNA polymerase II-independent recruitment of SPT6L at transcription start sites in Arabidopsis. Nucleic Acids Res. 2019;47:6714-6725 pubmed 出版商
|
| Miao H, Wang L, Zhan H, Dai J, Chang Y, Wu F, et al. A long noncoding RNA distributed in both nucleus and cytoplasm operates in the PYCARD-regulated apoptosis by coordinating the epigenetic and translational regulation. PLoS Genet. 2019;15:e1008144 pubmed 出版商
|
| Baluapuri A, Hofstetter J, Dudvarski Stankovic N, Endres T, Bhandare P, Vos S, et al. MYC Recruits SPT5 to RNA Polymerase II to Promote Processive Transcription Elongation. Mol Cell. 2019;74:674-687.e11 pubmed 出版商
|
| Hadzhiev Y, Qureshi H, Wheatley L, Cooper L, Jasiulewicz A, Van Nguyen H, et al. A cell cycle-coordinated Polymerase II transcription compartment encompasses gene expression before global genome activation. Nat Commun. 2019;10:691 pubmed 出版商
|
| Chen L, Lin Y, Gallegos D, Hazlett M, Gómez Schiavon M, Yang M, et al. Enhancer Histone Acetylation Modulates Transcriptional Bursting Dynamics of Neuronal Activity-Inducible Genes. Cell Rep. 2019;26:1174-1188.e5 pubmed 出版商
|
| Ma X, Yang T, Luo Y, Wu L, Jiang Y, Song Z, et al. TRIM28 promotes HIV-1 latency by SUMOylating CDK9 and inhibiting P-TEFb. elife. 2019;8: pubmed 出版商
|
| Verma S, De Jesus P, Chanda S, Verma I. SNW1, a Novel Transcriptional Regulator of the NF-κB Pathway. Mol Cell Biol. 2019;39: pubmed 出版商
|
| Zhang J, Zhang Y, Zhao L, Guo J, Yu J, Ji S, et al. Mammalian nucleolar protein DCAF13 is essential for ovarian follicle maintenance and oocyte growth by mediating rRNA processing. Cell Death Differ. 2019;26:1251-1266 pubmed 出版商
|
| Buxade M, Huerga Encabo H, Riera Borrull M, Quintana Gallardo L, López Cotarelo P, Tellechea M, et al. Macrophage-specific MHCII expression is regulated by a remote Ciita enhancer controlled by NFAT5. J Exp Med. 2018;215:2901-2918 pubmed 出版商
|
| Neueder A, Dumas A, Benjamin A, Bates G. Regulatory mechanisms of incomplete huntingtin mRNA splicing. Nat Commun. 2018;9:3955 pubmed 出版商
|
| Kistler K, Trcek T, Hurd T, Chen R, Liang F, Sall J, et al. Phase transitioned nuclear Oskar promotes cell division of Drosophila primordial germ cells. elife. 2018;7: pubmed 出版商
|
| Krause M, Love D, Ghosh S, Wang P, Yun S, Fukushige T, et al. Nutrient-Driven O-GlcNAcylation at Promoters Impacts Genome-Wide RNA Pol II Distribution. Front Endocrinol (Lausanne). 2018;9:521 pubmed 出版商
|
| Minzel W, Venkatachalam A, Fink A, Hung E, Brachya G, Burstain I, et al. Small Molecules Co-targeting CKIα and the Transcriptional Kinases CDK7/9 Control AML in Preclinical Models. Cell. 2018;175:171-185.e25 pubmed 出版商
|
| Das B, Dobrowolski C, Luttge B, Valadkhan S, Chomont N, Johnston R, et al. Estrogen receptor-1 is a key regulator of HIV-1 latency that imparts gender-specific restrictions on the latent reservoir. Proc Natl Acad Sci U S A. 2018;115:E7795-E7804 pubmed 出版商
|
| Minocha R, Popova V, Kopytova D, Misiak D, Huttelmaier S, Georgieva S, et al. Mud2 functions in transcription by recruiting the Prp19 and TREX complexes to transcribed genes. Nucleic Acids Res. 2018;46:9749-9763 pubmed 出版商
|
| Li S, Xu R, Li A, Liu K, Gu L, Li M, et al. SMA1, a homolog of the splicing factor Prp28, has a multifaceted role in miRNA biogenesis in Arabidopsis. Nucleic Acids Res. 2018;46:9148-9159 pubmed 出版商
|
| Balta E, Wittmann M, Jung M, Sock E, Haeberle B, Heim B, et al. Phosphorylation Modulates the Subcellular Localization of SOX11. Front Mol Neurosci. 2018;11:211 pubmed 出版商
|
| Parua P, Booth G, Sansó M, Benjamin B, Tanny J, Lis J, et al. A Cdk9-PP1 switch regulates the elongation-termination transition of RNA polymerase II. Nature. 2018;558:460-464 pubmed 出版商
|
| Aleksic T, Gray N, Wu X, Rieunier G, Osher E, Mills J, et al. Nuclear IGF1R Interacts with Regulatory Regions of Chromatin to Promote RNA Polymerase II Recruitment and Gene Expression Associated with Advanced Tumor Stage. Cancer Res. 2018;78:3497-3509 pubmed 出版商
|
| Cho S, Xu J, Sun R, Mumbach M, Carter A, Chen Y, et al. Promoter of lncRNA Gene PVT1 Is a Tumor-Suppressor DNA Boundary Element. Cell. 2018;173:1398-1412.e22 pubmed 出版商
|
| Sun W, Jiao S, Sun L, Zhou Z, Jin X, Wang J. SUN2 Modulates HIV-1 Infection and Latency through Association with Lamin A/C To Maintain the Repressive Chromatin. MBio. 2018;9: pubmed 出版商
|
| Shin H, He M, Yang Z, Jeon Y, Pfleger J, Sayed D, et al. Transcriptional regulation mediated by H2A.Z via ANP32e-dependent inhibition of protein phosphatase 2A. Biochim Biophys Acta Gene Regul Mech. 2018;1861:481-496 pubmed 出版商
|
| Chen L, Chen J, Huang Y, Gu Y, Qiu J, Qian H, et al. The Augmented R-Loop Is a Unifying Mechanism for Myelodysplastic Syndromes Induced by High-Risk Splicing Factor Mutations. Mol Cell. 2018;69:412-425.e6 pubmed 出版商
|
| Ray A, Katoch P, Jain N, Mehta P. Dileucine-like motifs in the C-terminal tail of connexin32 control its endocytosis and assembly into gap junctions. J Cell Sci. 2018;131: pubmed 出版商
|
| Su Y, Chen R, Wang H, Song H, Zhang Q, Chen L, et al. Novel Targeting of Transcription and Metabolism in Glioblastoma. Clin Cancer Res. 2018;24:1124-1137 pubmed 出版商
|
| Michelini F, Pitchiaya S, Vitelli V, Sharma S, Gioia U, Pessina F, et al. Damage-induced lncRNAs control the DNA damage response through interaction with DDRNAs at individual double-strand breaks. Nat Cell Biol. 2017;19:1400-1411 pubmed 出版商
|
| Whirledge S, Kisanga E, Taylor R, Cidlowski J. Pioneer Factors FOXA1 and FOXA2 Assist Selective Glucocorticoid Receptor Signaling in Human Endometrial Cells. Endocrinology. 2017;158:4076-4092 pubmed 出版商
|
| Ghosh S, Wallerath C, Covarrubias S, Hornung V, Carpenter S, Fitzgerald K. The PYHIN Protein p205 Regulates the Inflammasome by Controlling Asc Expression. J Immunol. 2017;199:3249-3260 pubmed 出版商
|
| Pae J, Cinalli R, Marzio A, Pagano M, Lehmann R. GCL and CUL3 Control the Switch between Cell Lineages by Mediating Localized Degradation of an RTK. Dev Cell. 2017;42:130-142.e7 pubmed 出版商
|
| Gates L, Shi J, Rohira A, Feng Q, Zhu B, Bedford M, et al. Acetylation on histone H3 lysine 9 mediates a switch from transcription initiation to elongation. J Biol Chem. 2017;292:14456-14472 pubmed 出版商
|
| Lu X, Batugedara G, Lee M, Prudhomme J, Bunnik E, Le Roch K. Nascent RNA sequencing reveals mechanisms of gene regulation in the human malaria parasite Plasmodium falciparum. Nucleic Acids Res. 2017;45:7825-7840 pubmed 出版商
|
| Aldiri I, Xu B, Wang L, Chen X, Hiler D, Griffiths L, et al. The Dynamic Epigenetic Landscape of the Retina During Development, Reprogramming, and Tumorigenesis. Neuron. 2017;94:550-568.e10 pubmed 出版商
|
| Lee Y, Park D, Iyer V. The ATP-dependent chromatin remodeler Chd1 is recruited by transcription elongation factors and maintains H3K4me3/H3K36me3 domains at actively transcribed and spliced genes. Nucleic Acids Res. 2017;45:7180-7190 pubmed 出版商
|
| Fuller M, Majumder K, Pintel D. Minute Virus of Mice Inhibits Transcription of the Cyclin B1 Gene during Infection. J Virol. 2017;91: pubmed 出版商
|
| He R, Kidder B. H3K4 demethylase KDM5B regulates global dynamics of transcription elongation and alternative splicing in embryonic stem cells. Nucleic Acids Res. 2017;45:6427-6441 pubmed 出版商
|
| Zaghloul E, Gissberg O, Moreno P, Siggens L, Hällbrink M, Jørgensen A, et al. CTG repeat-targeting oligonucleotides for down-regulating Huntingtin expression. Nucleic Acids Res. 2017;45:5153-5169 pubmed 出版商
|
| Shadle S, Zhong J, Campbell A, Conerly M, Jagannathan S, Wong C, et al. DUX4-induced dsRNA and MYC mRNA stabilization activate apoptotic pathways in human cell models of facioscapulohumeral dystrophy. PLoS Genet. 2017;13:e1006658 pubmed 出版商
|
| Kalinava N, Ni J, Peterman K, Chen E, Gu S. Decoupling the downstream effects of germline nuclear RNAi reveals that H3K9me3 is dispensable for heritable RNAi and the maintenance of endogenous siRNA-mediated transcriptional silencing in Caenorhabditis elegans. Epigenetics Chromatin. 2017;10:6 pubmed 出版商
|
| Lee J, Choi E, Seo H, Kang K, Gilmore J, Florens L, et al. Chromatin remodeller Fun30Fft3 induces nucleosome disassembly to facilitate RNA polymerase II elongation. Nat Commun. 2017;8:14527 pubmed 出版商
|
| Borsos B, Huliák I, Majoros H, Ujfaludi Z, Gyenis A, Pukler P, et al. Human p53 interacts with the elongating RNAPII complex and is required for the release of actinomycin D induced transcription blockage. Sci Rep. 2017;7:40960 pubmed 出版商
|
| Hang S, Gergen J. Different modes of enhancer-specific regulation by Runt and Even-skipped during Drosophila segmentation. Mol Biol Cell. 2017;28:681-691 pubmed 出版商
|
| Liu X, Gao Y, Ye H, Gerrin S, Ma F, Wu Y, et al. Positive feedback loop mediated by protein phosphatase 1α mobilization of P-TEFb and basal CDK1 drives androgen receptor in prostate cancer. Nucleic Acids Res. 2017;45:3738-3751 pubmed 出版商
|
| Park S, Jwa E, Shin S, Ju E, Park I, Pak J, et al. Ibulocydine sensitizes human hepatocellular carcinoma cells to TRAIL-induced apoptosis via calpain-mediated Bax cleavage. Int J Biochem Cell Biol. 2017;83:47-55 pubmed 出版商
|
| Hirano Y, Ihara K, Masuda T, Yamamoto T, Iwata I, Takahashi A, et al. Shifting transcriptional machinery is required for long-term memory maintenance and modification in Drosophila mushroom bodies. Nat Commun. 2016;7:13471 pubmed 出版商
|
| Anderson K, Anderson D, McAnally J, Shelton J, Bassel Duby R, Olson E. Transcription of the non-coding RNA upperhand controls Hand2 expression and heart development. Nature. 2016;539:433-436 pubmed 出版商
|
| Deshmukh A, Mitra P, Maruthi M. Cdk7 mediates RPB1-driven mRNA synthesis in Toxoplasma gondii. Sci Rep. 2016;6:35288 pubmed 出版商
|
| Ishiguro K, Monti M, Akiyama T, Kimura H, Chikazawa Nohtomi N, Sakota M, et al. Zscan4 is expressed specifically during late meiotic prophase in both spermatogenesis and oogenesis. In Vitro Cell Dev Biol Anim. 2017;53:167-178 pubmed 出版商
|
| Navarro Costa P, McCarthy A, Prudêncio P, Greer C, Guilgur L, Becker J, et al. Early programming of the oocyte epigenome temporally controls late prophase I transcription and chromatin remodelling. Nat Commun. 2016;7:12331 pubmed 出版商
|
| Saayman S, Ackley A, Burdach J, Clemson M, Gruenert D, Tachikawa K, et al. Long Non-coding RNA BGas Regulates the Cystic Fibrosis Transmembrane Conductance Regulator. Mol Ther. 2016;24:1351-7 pubmed 出版商
|
| Kos I, Patterson M, Znaidi S, Kaloriti D, da Silva Dantas A, Herrero de Dios C, et al. Mechanisms Underlying the Delayed Activation of the Cap1 Transcription Factor in Candida albicans following Combinatorial Oxidative and Cationic Stress Important for Phagocytic Potency. MBio. 2016;7:e00331 pubmed 出版商
|
| Portnoy V, Lin S, Li K, Burlingame A, Hu Z, Li H, et al. saRNA-guided Ago2 targets the RITA complex to promoters to stimulate transcription. Cell Res. 2016;26:320-35 pubmed 出版商
|
| Ni J, Kalinava N, Chen E, Huang A, Trinh T, Gu S. A transgenerational role of the germline nuclear RNAi pathway in repressing heat stress-induced transcriptional activation in C. elegans. Epigenetics Chromatin. 2016;9:3 pubmed 出版商
|
| Chou C, Pinto A, Curtis J, Persaud S, Cella M, Lin C, et al. c-Myc-induced transcription factor AP4 is required for host protection mediated by CD8+ T cells. Nat Immunol. 2014;15:884-93 pubmed 出版商
|