产品简要
公司名称 :
艾博抗(上海)贸易有限公司
其他品牌 :
Epitomics, Ascent Scientific, MitoSciences
产品类型 :
抗体
产品名称 :
抗MMP14抗体[EP1264Y]
目录 :
ab51074
规格 :
10微升, 100微升
克隆性 :
单克隆
宿主 :
共轭标签 :
未共轭
克隆名称 :
EP1264Y
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀, 流式细胞仪, 免疫组化-石蜡切片, 免疫组化-冰冻切片, 免疫印迹基因敲除验证
文章摘录数: 43
出版应用/物种/样本/稀释参考文献
  • 免疫组化-石蜡切片; 人类; 1:500; 图 s108
Rickelt S, Hynes R. Antibodies and methods for immunohistochemistry of extracellular matrix proteins. Matrix Biol. 2018;71-72:10-27 pubmed 出版商
  • 免疫细胞化学; 人类; 图 2e
Swayampakula M, McDonald P, Vallejo M, Coyaud E, Chafe S, Westerback A, et al. The interactome of metabolic enzyme carbonic anhydrase IX reveals novel roles in tumor cell migration and invadopodia/MMP14-mediated invasion. Oncogene. 2017;36:6244-6261 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 4d
Dourado K, Baik J, Oliveira V, Beltrame M, Yamamoto A, Theuer C, et al. Endoglin: a novel target for therapeutic intervention in acute leukemias revealed in xenograft mouse models. Blood. 2017;129:2526-2536 pubmed 出版商
  • 免疫印迹; 人类; 图 7a
Bertier L, Boucherie C, Zwaenepoel O, Vanloo B, Van Troys M, Van Audenhove I, et al. Inhibitory cortactin nanobodies delineate the role of NTA- and SH3-domain-specific functions during invadopodium formation and cancer cell invasion. FASEB J. 2017;31:2460-2476 pubmed 出版商
  • 免疫印迹; 人类; 图 1a
Bogachek M, Park J, De Andrade J, Lorenzen A, Kulak M, White J, et al. Inhibiting the SUMO Pathway Represses the Cancer Stem Cell Population in Breast and Colorectal Carcinomas. Stem Cell Reports. 2016;7:1140-1151 pubmed 出版商
  • 免疫细胞化学; 人类; 图 1c
  • 免疫印迹; 人类; 图 3c
Daubon T, Spuul P, Alonso F, Fremaux I, Genot E. VEGF-A stimulates podosome-mediated collagen-IV proteolysis in microvascular endothelial cells. J Cell Sci. 2016;129:2586-98 pubmed 出版商
  • 免疫印迹基因敲除验证; 小鼠; 1:2000; 图 3
Wong H, Jin G, Cao R, Zhang S, Cao Y, Zhou Z. MT1-MMP sheds LYVE-1 on lymphatic endothelial cells and suppresses VEGF-C production to inhibit lymphangiogenesis. Nat Commun. 2016;7:10824 pubmed 出版商
  • 免疫组化; 小鼠; 1:50; 图 4
Tsaousi A, Hayes E, Di Gregoli K, Bond A, Bevan L, Thomas A, et al. Plaque Size Is Decreased but M1 Macrophage Polarization and Rupture Related Metalloproteinase Expression Are Maintained after Deleting T-Bet in ApoE Null Mice. PLoS ONE. 2016;11:e0148873 pubmed 出版商
  • 免疫组化-石蜡切片; 大鼠; 1:200; 图 s2
  • 免疫印迹; 大鼠
Zhao W, Wang C, Liu R, Wei C, Duan J, Liu K, et al. Effect of TGF-β1 on the Migration and Recruitment of Mesenchymal Stem Cells after Vascular Balloon Injury: Involvement of Matrix Metalloproteinase-14. Sci Rep. 2016;6:21176 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 3d
Ding B, Gomi K, Rafii S, Crystal R, Walters M. Endothelial MMP14 is required for endothelial-dependent growth support of human airway basal cells. J Cell Sci. 2015;128:2983-8 pubmed 出版商
  • 免疫细胞化学; 人类; 1:200
Ho F, Zhang W, Li Y, Chan B. Mechanoresponsive, omni-directional and local matrix-degrading actin protrusions in human mesenchymal stem cells microencapsulated in a 3D collagen matrix. Biomaterials. 2015;53:392-405 pubmed 出版商
  • 免疫印迹; 人类; 图 7
Calabro S, Maczurek A, Morgan A, Tu T, Wen V, Yee C, et al. Hepatocyte produced matrix metalloproteinases are regulated by CD147 in liver fibrogenesis. PLoS ONE. 2014;9:e90571 pubmed 出版商
  • 流式细胞仪; 人类; 图 1
Havre P, Dang L, Ohnuma K, Iwata S, Morimoto C, Dang N. CD26 expression on T-anaplastic large cell lymphoma (ALCL) line Karpas 299 is associated with increased expression of versican and MT1-MMP and enhanced adhesion. BMC Cancer. 2013;13:517 pubmed 出版商
  • 免疫印迹; 人类
Kuttner V, Mack C, Rigbolt K, Kern J, Schilling O, Busch H, et al. Global remodelling of cellular microenvironment due to loss of collagen VII. Mol Syst Biol. 2013;9:657 pubmed 出版商
  • 免疫细胞化学; 小鼠
Ming X, Rajapakse A, Yepuri G, Xiong Y, Carvas J, Ruffieux J, et al. Arginase II Promotes Macrophage Inflammatory Responses Through Mitochondrial Reactive Oxygen Species, Contributing to Insulin Resistance and Atherogenesis. J Am Heart Assoc. 2012;1:e000992 pubmed 出版商
  • 免疫组化-冰冻切片; 人类; 1:200
Farahani R, Sarrafpour B, Simonian M, Li Q, Hunter N. Directed glia-assisted angiogenesis in a mature neurosensory structure: pericytes mediate an adaptive response in human dental pulp that maintains blood-barrier function. J Comp Neurol. 2012;520:3803-26 pubmed 出版商
Hoffmann C, Mao X, Brown Clay J, Moreau F, Al Absi A, Wurzer H, et al. Hypoxia promotes breast cancer cell invasion through HIF-1?-mediated up-regulation of the invadopodial actin bundling protein CSRP2. Sci Rep. 2018;8:10191 pubmed 出版商
Pekkonen P, Alve S, Balistreri G, Gramolelli S, Tatti Bugaeva O, Paatero I, et al. Lymphatic endothelium stimulates melanoma metastasis and invasion via MMP14-dependent Notch3 and β1-integrin activation. elife. 2018;7: pubmed 出版商
Sakr M, Li X, Sabeh F, Feinberg T, Tesmer J, Tang Y, et al. Tracking the Cartoon mouse phenotype: Hemopexin domain-dependent regulation of MT1-MMP pericellular collagenolytic activity. J Biol Chem. 2018;293:8113-8127 pubmed 出版商
Li T, Yi L, Hai L, Ma H, Tao Z, Zhang C, et al. The interactome and spatial redistribution feature of Ca2+ receptor protein calmodulin reveals a novel role in invadopodia-mediated invasion. Cell Death Dis. 2018;9:292 pubmed 出版商
Colombo A, Hsia H, Wang M, Kuhn P, Brill M, Canevazzi P, et al. Non-cell-autonomous function of DR6 in Schwann cell proliferation. EMBO J. 2018;37: pubmed 出版商
Majkowska I, Shitomi Y, Ito N, Gray N, Itoh Y. Discoidin domain receptor 2 mediates collagen-induced activation of membrane-type 1 matrix metalloproteinase in human fibroblasts. J Biol Chem. 2017;292:6633-6643 pubmed 出版商
DU H, Liu P. Matrix metalloproteinase 14 participates in corneal lymphangiogenesis through the VEGF-C/VEGFR-3 signaling pathway. Exp Ther Med. 2016;12:2120-2128 pubmed
Petropoulos C, Oddou C, Emadali A, Hiriart Bryant E, Boyault C, Faurobert E, et al. Roles of paxillin family members in adhesion and ECM degradation coupling at invadosomes. J Cell Biol. 2016;213:585-99 pubmed 出版商
Chen J, Chen P, Backman L, Zhou Q, Danielson P. Ciliary Neurotrophic Factor Promotes the Migration of Corneal Epithelial Stem/progenitor Cells by Up-regulation of MMPs through the Phosphorylation of Akt. Sci Rep. 2016;6:25870 pubmed 出版商
Gallardo Vara E, Blanco F, Roqué M, Friedman S, Suzuki T, Botella L, et al. Transcription factor KLF6 upregulates expression of metalloprotease MMP14 and subsequent release of soluble endoglin during vascular injury. Angiogenesis. 2016;19:155-71 pubmed 出版商
Shitomi Y, Thøgersen I, Ito N, Leitinger B, Enghild J, Itoh Y. ADAM10 controls collagen signaling and cell migration on collagen by shedding the ectodomain of discoidin domain receptor 1 (DDR1). Mol Biol Cell. 2015;26:659-73 pubmed 出版商
Hayes E, Tsaousi A, Di Gregoli K, Jenkinson S, Bond A, Johnson J, et al. Classical and Alternative Activation and Metalloproteinase Expression Occurs in Foam Cell Macrophages in Male and Female ApoE Null Mice in the Absence of T and B Lymphocytes. Front Immunol. 2014;5:537 pubmed 出版商
Wang Y, Zhang Y, Kong C, Zhang Z, Zhu Y. Loss of P53 facilitates invasion and metastasis of prostate cancer cells. Mol Cell Biochem. 2013;384:121-7 pubmed 出版商
Xiao W, Jiang M, Li H, Li C, Su R, Huang K. Knockdown of FAK inhibits the invasion and metastasis of Tca?8113 cells in vitro. Mol Med Rep. 2013;8:703-7 pubmed 出版商
Lee J, Kang J, Song K, Jeon S, Oh S, Kim Y, et al. N-Acetylglucosaminyltransferase V triggers overexpression of MT1-MMP and reinforces the invasive/metastatic potential of cancer cells. Biochem Biophys Res Commun. 2013;431:658-63 pubmed 出版商
Rezvani H, Ali N, Serrano Sanchez M, Dubus P, Varon C, Ged C, et al. Loss of epidermal hypoxia-inducible factor-1? accelerates epidermal aging and affects re-epithelialization in human and mouse. J Cell Sci. 2011;124:4172-83 pubmed 出版商
Urso M, Wang R, Zambraski E, Liang B. Adenosine A3 receptor stimulation reduces muscle injury following physical trauma and is associated with alterations in the MMP/TIMP response. J Appl Physiol (1985). 2012;112:658-70 pubmed 出版商
Bernert B, Porsch H, Heldin P. Hyaluronan synthase 2 (HAS2) promotes breast cancer cell invasion by suppression of tissue metalloproteinase inhibitor 1 (TIMP-1). J Biol Chem. 2011;286:42349-59 pubmed 出版商
Ferraro G, Morrison C, Overall C, Strittmatter S, Fournier A. Membrane-type matrix metalloproteinase-3 regulates neuronal responsiveness to myelin through Nogo-66 receptor 1 cleavage. J Biol Chem. 2011;286:31418-24 pubmed 出版商
Bialek J, Kunanuvat U, Hombach Klonisch S, Spens A, Stetefeld J, Sunley K, et al. Relaxin enhances the collagenolytic activity and in vitro invasiveness by upregulating matrix metalloproteinases in human thyroid carcinoma cells. Mol Cancer Res. 2011;9:673-87 pubmed 出版商
Miller J, Holcomb J, Al Ramahi I, de Haro M, Gafni J, Zhang N, et al. Matrix metalloproteinases are modifiers of huntingtin proteolysis and toxicity in Huntington's disease. Neuron. 2010;67:199-212 pubmed 出版商
Hawinkels L, Kuiper P, Wiercinska E, Verspaget H, Liu Z, Pardali E, et al. Matrix metalloproteinase-14 (MT1-MMP)-mediated endoglin shedding inhibits tumor angiogenesis. Cancer Res. 2010;70:4141-50 pubmed 出版商
Triantafyllopoulou A, Franzke C, Seshan S, Perino G, Kalliolias G, Ramanujam M, et al. Proliferative lesions and metalloproteinase activity in murine lupus nephritis mediated by type I interferons and macrophages. Proc Natl Acad Sci U S A. 2010;107:3012-7 pubmed 出版商
Saha A, Lee Y, Zhang Z, Chandra G, Su S, Mukherjee A. Lack of an endogenous anti-inflammatory protein in mice enhances colonization of B16F10 melanoma cells in the lungs. J Biol Chem. 2010;285:10822-31 pubmed 出版商
Agrawal V, Johnson S, Reing J, Zhang L, Tottey S, Wang G, et al. Epimorphic regeneration approach to tissue replacement in adult mammals. Proc Natl Acad Sci U S A. 2010;107:3351-5 pubmed 出版商
Barnes B, Szelenyi E, Warren G, Urso M. Alterations in mRNA and protein levels of metalloproteinases-2, -9, and -14 and tissue inhibitor of metalloproteinase-2 responses to traumatic skeletal muscle injury. Am J Physiol Cell Physiol. 2009;297:C1501-8 pubmed 出版商
Kogianni G, Walker M, Waxman J, Sturge J. Endo180 expression with cofunctional partners MT1-MMP and uPAR-uPA is correlated with prostate cancer progression. Eur J Cancer. 2009;45:685-93 pubmed 出版商
产品信息
目录号 :
ab51074
ItemName :
抗MMP14抗体[EP1264Y]
类别 :
抗体
宿主 :
克隆性 :
单克隆
共轭标签 :
未共轭
克隆名称 :
EP1264Y
规格 :
10微升, 100微升
物种摘要 :
Hu, Ms, Rat
应用摘要 :
Flow Cyt, ICC/IF, IHC-P, IP, WB
公司信息
艾博抗(上海)贸易有限公司
上海市浦东新区伽利略路338号5幢4层5401室
cn.technical@abcam.com
http://www.abcam.cn
400-628-6880 86-21-5110 5938
公司总部: 英国
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